This is the video on Multiple Myeloma and Bence Jones Protein
00:00 - Introduction
00:24 - Multiple Myeloma
01:44 - Clinical Features of Multiple Myeloma
02:12 - MNEMONIC to Remember Clinical Features of Multiple Myeloma
02:29 - Diagnosis of Multiple Myeloma
02:56 - M Band in Electrophoresis
03:48 - Bence Jones Proteins
05:03 - Treatment of Multiple Myeloma
Multiple myeloma (Plasma Cell Myeloma) is cancer of Plasma Cells.
Abnormal plasma cells produce abnormal antibodies which cause kidney problems and overly thick blood.
Plasma cells also form mass in the bone marrow or soft tissue.
When one tumour is present it is called plasmacytoma, more than one is called multiple myeloma
In 20% cases of MM the light chains of immunoglobulins are produced abnormally.
Being small molecular weight they are excreted in urine.
These are called Bence Jones Protein.
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