NASA astronauts Matthew Dominick, Michael Barratt, and Jeanette Epps, and Roscosmos cosmonaut Alexander Grebenkin arrived at the International Space Station when their Dragon spacecraft autonomously docked to the forward-facing port of the Harmony module at 2:28 a.m. Eastern Standard Time on March 5 following a launch on March 3 on the Endeavour spacecraft aboard a Falcon 9 rocket from Launch Complex 39A at the agency’s Kennedy Space Center in Florida. Following docking, the quartet opened the hatch and floated onboard the orbital outpost before providing welcoming remarks as its mission aboard the space station began. The four crew members will conduct a long-duration science mission living and working aboard the microgravity laboratory to advance scientific knowledge and demonstrate new technologies for future human and robotic exploration missions. Such research benefits people on Earth and lays the groundwork for future human exploration through the agency’s Artemis missions, which will send astronauts to the Moon to prepare for future expeditions to Mars.