The FDA has approved a gene therapy gel developed at Stanford Medicine. The treatment has helped improve wound healing for patients with a blistering skin disease called dystrophic epidermolysis bullosa. They often suffer from large open wounds that last for years or decades. It’s an intensely painful condition, and medical treatment for it has been limited largely to palliative care.
A double-blind, placebo-controlled clinical trial of a gene therapy gel developed at Stanford Medicine shows improved wound healing in 31 people with the disease, including 19 who were 18 years old or younger. Sixty-seven percent of wounds treated with the gel, which is applied to the skin during bandage changes, completely healed after six months of weekly applications, while only 22% of wounds treated with a placebo did so.
Read the full story: stan.md/3V5GSAh
Peter Marinkovich, MD, is an associate professor of dermatology, a faculty member of the program in epithelial biology and the Stanford Cancer Biology Program. He has an interest in inflammatory skin disease and is director of the Stanford Bullous Disease and Psoriasis Clinics.
Lisa Kim is Senior Manager of Media Relations for Stanford Medicine and Stanford Health Care. Lisa has a deep background in journalism, as she is an Emmy Award-winning journalist who has covered stories on both the national and local levels.
Gene-therapy gel shows promise for blistering skin disease in clinical trial:
stan.md/3uDMwyc
Dramatic experimental gene therapy advance for blistering disease wound care: stan.md/3Yz6is3
#EB #Dermatology #Research
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