Paracetamol (Acetaminophen) hepatotoxicity and its management.

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Pharmacology Animation

Pharmacology Animation

Күн бұрын

This animated video illustrates the mechanisms of Paracetamol (Acetaminophen) induce hepatotoxicity.
It compares the production of toxic intermediate NAPQI under both therapeutic and toxic concentration of paracetamol.
Glutathions plays important role in transforming NAPQI into water soluble no toxic metabolite that is readily excreted by the kidney
This video also explain why paracetamol induces hepatotoxicity even under normal therapeutic doses in some unfortunate people.
lastly this video briefly explains the pharmacological bases behind using N-Acetyl Cysteine as antidote for paracetamol poisoning

Пікірлер: 65
@godzillajuvana6342
@godzillajuvana6342 4 жыл бұрын
the pace of explanation is perfect for me who keeps on forgetting what is what and very understandable.
@ajayjat1914
@ajayjat1914 3 жыл бұрын
Just incredible explanation! Huge thanks teacher!
@elizabethominde-ogaja3433
@elizabethominde-ogaja3433 3 жыл бұрын
This is the best account of paracetamol metabolism and toxicity that I have seen any where. Thank you, thank you thank you. Have you made any other videos?
@aliaub75
@aliaub75 3 жыл бұрын
Perfect explanation...barak Allahu feekum. My dua and thoughts go to the beautiful people in Gaza.
@brianchuma3152
@brianchuma3152 3 жыл бұрын
This is very good tutorial ......it makes medicine more easier
@mistykidowo
@mistykidowo 2 жыл бұрын
Love the way you explain things. Thanks
@ClassofEmergencyMedicine
@ClassofEmergencyMedicine 3 жыл бұрын
very good video. a must for exam going students
@rehanulislam2419
@rehanulislam2419 Жыл бұрын
Very nice presentation.
@nakatokaren505
@nakatokaren505 2 жыл бұрын
Thank you very much. This has helped summarise my assignment.
@samitasapkota6026
@samitasapkota6026 3 жыл бұрын
very perfectly explained..Thank you!!
@caitygart
@caitygart 2 жыл бұрын
Wonderful explanation, thank you so much!
@radhwanabdulla6806
@radhwanabdulla6806 Жыл бұрын
Jzk well done . I hope you have more videos to watch
@ahmedali-bk2rx
@ahmedali-bk2rx 5 ай бұрын
بلقرأن شرح رهيب عاشت ايدكم وربي يوفقكم ❤❤❤❤
@A2G_tricks
@A2G_tricks 3 жыл бұрын
wow its perfect so nicely explain . thanks
@shb9337
@shb9337 Жыл бұрын
Great helpful explanation
@katherineswart474
@katherineswart474 Жыл бұрын
excellent video-recommended
@monielf-7340
@monielf-7340 8 ай бұрын
Superb work 👏🏽LOVE IT ❤
@alesandrom5636
@alesandrom5636 3 жыл бұрын
Great 👍
@rusulabdalkreem9098
@rusulabdalkreem9098 Ай бұрын
عاشت ايدك دكتورة على هذا الشرح العظيم
@radhwanabdulla6806
@radhwanabdulla6806 Жыл бұрын
Great Jehad
@marwaemad7728
@marwaemad7728 7 ай бұрын
thank you so much what a beautiful explanation
@ABDULLAHMALIK
@ABDULLAHMALIK 2 жыл бұрын
excellent explanation
@smartprogramming1107
@smartprogramming1107 3 жыл бұрын
Very nice explanation madam keep it up god bless you
@rn6041
@rn6041 2 жыл бұрын
Amazing!Thank you
@nabinkumaryadav9351
@nabinkumaryadav9351 3 жыл бұрын
Thanks a lot ..it helps me a lot
@sylvesterstallone1165
@sylvesterstallone1165 3 жыл бұрын
Thank u very much for this nice explanation😊
@ghadeeradel5471
@ghadeeradel5471 3 жыл бұрын
ممتاز ,بالتوفيق يارب ,thank you
@SAPANAACHARYA-gz2xm
@SAPANAACHARYA-gz2xm 5 ай бұрын
super explanation
@Call_Ins
@Call_Ins Жыл бұрын
Thanks for the video
@ghaziturki9756
@ghaziturki9756 3 жыл бұрын
Helpful🌺🌺🌺🌺
@philadelphiachr922
@philadelphiachr922 2 жыл бұрын
THANK YOU OMG MUCH NEEDED
@hi-s
@hi-s 2 жыл бұрын
Awesome
@alhumairahassan1643
@alhumairahassan1643 2 жыл бұрын
good video
@laugh_with_jenny3011
@laugh_with_jenny3011 Жыл бұрын
You are superb
@harshithcherla9521
@harshithcherla9521 2 жыл бұрын
Thank you!
@ahmedayesh3728
@ahmedayesh3728 3 жыл бұрын
very nice
@ADDZZ361
@ADDZZ361 3 жыл бұрын
Thank you very much sis !
@d-ii-b
@d-ii-b 4 ай бұрын
كل الحب لأخوتن في غزة ❤
@lauriegunn9573
@lauriegunn9573 3 жыл бұрын
Nice, but if there anyway we can take NAC orally to offset problems with proloned need for Tylenol for pain??
@sireenma98
@sireenma98 2 жыл бұрын
Thank you so much, It really helped me I'm so proud of our Palestinian doctors
@ayaaya2007
@ayaaya2007 Жыл бұрын
Thanks ❤
@itssomeone4407
@itssomeone4407 2 жыл бұрын
Amazig allah bless you
@sureshnerlekar4713
@sureshnerlekar4713 Жыл бұрын
What a fantastic way of explanation of this article ,by diagrammatic way and the speed at which it is narrated,to understand the procedure.THANQ.Sameway can you explain ,disintegration,toxicity and treatment of Ibuprofen.normal & overdose.?
@PharmacologyAnimation
@PharmacologyAnimation Жыл бұрын
Thank you so much. Regarding ibuprofen there is a detailed video in this channel titled NSAIDs which covers the side effects of ibuprofen. That video was narrated by Professor Susan Brain the former Head of Pharmacology Department at Kings College London University.
@brightizogie9734
@brightizogie9734 Жыл бұрын
Ur voice is very romantic....can't stop watching over n over again....I love u
@mohsentavakoli6319
@mohsentavakoli6319 3 жыл бұрын
thx
@susanclara6611
@susanclara6611 2 жыл бұрын
Congratulations
@eeshaumer607
@eeshaumer607 2 жыл бұрын
thank you thank you thank you thank you thank you thank you thank you thank you
@JohnSmith-ox3gy
@JohnSmith-ox3gy 2 жыл бұрын
My liver thanks you. I will be more considerate of paracetamol usage and try to limit it to use only when having high fever.
@user-ge3gt4yk6w
@user-ge3gt4yk6w 5 ай бұрын
I hop you and your doctor are still okay🥺🙏
@MuhammadAli-ml9bt
@MuhammadAli-ml9bt 3 жыл бұрын
wow
@anwark20
@anwark20 7 ай бұрын
❤❤❤
@sylvesterstallone1165
@sylvesterstallone1165 4 жыл бұрын
A veryyyy nice video I liked it But What is the usual toxic dose of paracetamol?
@grmka8623
@grmka8623 Жыл бұрын
Hocam 🧿🧿
@radhwanabdulla6806
@radhwanabdulla6806 Жыл бұрын
Salam from London
@PharmacologyAnimation
@PharmacologyAnimation Жыл бұрын
Salam Radhwan. Have we met before in london? if not I am happy to meet you at KCL.
@Ravifddccvf
@Ravifddccvf 6 ай бұрын
Paracetamol is immunosuppressive drugs?
@billiewilly401
@billiewilly401 3 жыл бұрын
will I die from taking 25 im 15
@gjzztrrettmmggrrertzhgyena4950
@gjzztrrettmmggrrertzhgyena4950 4 жыл бұрын
WwwwwwaaaaaaWWWWW 💚🧡💚🧡💚
@nozt0lgia716
@nozt0lgia716 3 жыл бұрын
Will I die from taking 4 of them
@Dr.Thalekkallan
@Dr.Thalekkallan 3 жыл бұрын
7.5 gram is toxic level
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