Parkinson's Disease Drugs

  Рет қаралды 127,146

Ninja Nerd

Ninja Nerd

Күн бұрын

Official Ninja Nerd Website: ninjanerd.org
You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
www.ninjanerd.org/lecture/par...
Ninja Nerds!
In this lecture Professor Zach Murphy will be presenting on Parkinson's Disease Medications. During this lecture we will start by reviewing the Basal Ganglia Anatomy and Physiology. We will also be reviewing the direct and indirect pathway that is affected with Parkinson's disease. We will then transition into the various drug categories used to treat Parkinson's which includes Levodopa or L-Dopa, Dopamine Agonists, COMT inhibitors, MAO-B inhibitors, Amantadine, and Anticholinergics. We hope you enjoy this lecture and be sure to support us below!
Table of Contents:
0:00 Lab
0:07 Parkinson’s Disease Medications Introduction
1:20 Basal Ganglia Anatomy
4:23 Direct vs. Indirect Pathway
18:23 Pathophysiology of Parkinson’s Disease
21:26 Drug Classes for Parkinson’s Disease
24:36 Mechanism of Action
38:51 L-Dopa + Carbidopa
1:00:22 Dopamine Agonists
1:06:08 COMT-Inhibitors
1:11:39 MAO-B-Inhibitors
1:20:12 Amantadine
1:27:10 Anticholinergics
1:31:18 PD Medications - Practice Problems
1:36:13 Comment, Like, SUBSCRIBE!
Supplemental Lectures:
Basal Ganglia - • Neurology | Basal Gang...
Pharmacology Source:
Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition.
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#ninjanerd #parkinsonsdisease #pharmacology

Пікірлер: 186
@aneesazafar9646
@aneesazafar9646 Жыл бұрын
You are remarkable, I have never met a teacher like you.
@smoovlatino
@smoovlatino 6 ай бұрын
I am speechless at how gifted you are in teaching. We must protect this man.
@HarshPatel-he2vh
@HarshPatel-he2vh 2 ай бұрын
From whom? no one hates him😭
@silviamontisci6399
@silviamontisci6399 Жыл бұрын
Italian medical student here! I'm glad I found you on YT, you're such a life-saver. Thank you for sharing your passion for these subjects, you're amazing man! (and your staff too, of course)
@deerfashion
@deerfashion Жыл бұрын
Starting an assignment on PD meds for my pharmacology class today! SO perfect!😍
@Lotus-iz3ic
@Lotus-iz3ic Жыл бұрын
Actually I've been struggling with Parkinson's drugs and mechanisms as I used to hate pharmacology the first medical year in college but this video definitely make it way too easier , I am really feeling grateful, thank you a lot ❤❤❤❤ you are the greatest 💪🏻
@madisonwatt329
@madisonwatt329 8 ай бұрын
Your videos are amazing! Clears up so much information left out by professors! Thank you for everything you do.
@faiza.m9974
@faiza.m9974 Жыл бұрын
Amazing this video save me, I spend many days to read textbooks and watching my lectures and I feel so dumb but now this video is totally make sense to me and put everything I’ve read together, thank you so much 🎉
@AnnMulvihill-lt9qz
@AnnMulvihill-lt9qz 9 ай бұрын
You are Excellent. Great teacher. Thanks from retired RNBSN with Parkin sons. Still with thrist for knowledge to understand. Thanks.
@yvonnevillalba7722
@yvonnevillalba7722 Жыл бұрын
You truly are the best teacher ever! Thank you for this video.
@chinnyogbonna6506
@chinnyogbonna6506 Жыл бұрын
I love your passion and teaching, always amazed. Thank you very much.
@khalilahd.
@khalilahd. Жыл бұрын
So helpful. Thank you! ❤
@ella-meow1116
@ella-meow1116 Жыл бұрын
please please continue making pharmacology videos ,as pharmacy student i find these so helpful thank you for your effort
@niharikasaraf3506
@niharikasaraf3506 Жыл бұрын
I never bothered learning WHY we used COMT and MAO B inhibitors before this video, damn thank you!!
@steveh1460
@steveh1460 Жыл бұрын
Love your passion for teaching! Thank you!
@direxsama258
@direxsama258 Жыл бұрын
didnt watch this yet but without doubtes i know it will be a BANGER Thank you Dr
@s_l_m__
@s_l_m__ Жыл бұрын
Extraordinarily well made video. Thank you, Zach
@leticiadermith9832
@leticiadermith9832 23 күн бұрын
You have a gift and I am so grateful for your existence on this earth and time.
@kathikloeckner6118
@kathikloeckner6118 Жыл бұрын
I love your memory and your passion! ROCK STAR!
@jis2937
@jis2937 Жыл бұрын
I’m grateful for your existence, you do matter & we appreciate u
@ayanafrancis6294
@ayanafrancis6294 Жыл бұрын
You are a saviour .Thank you zach🔥
@faisalqasmi9543
@faisalqasmi9543 Жыл бұрын
Be healthy sir 🙏 we really need you
@sadiajafar5792
@sadiajafar5792 Жыл бұрын
I love the way you you teach I think your are the bestest teacher in this whole world 🌍
@mmsah30
@mmsah30 Жыл бұрын
i love u man, u made it easy on me to understand the topics
@francescacovre7526
@francescacovre7526 Жыл бұрын
You are my saver for any exam preparation
@biybimaryamjoldasbaeva506
@biybimaryamjoldasbaeva506 4 ай бұрын
Thanks a lot for the perfect lecture!
@tanveerabdullah3297
@tanveerabdullah3297 Жыл бұрын
Kindly make videos on antidepressents and anxiolytics ...plz
@mariapereiramd7173
@mariapereiramd7173 Жыл бұрын
Thank you for this video!
@mmdohhmod7622
@mmdohhmod7622 Жыл бұрын
You are awesome teacher, Man... Thanks for everything
@user-sb7rs4tp2l
@user-sb7rs4tp2l 7 ай бұрын
we need more pharmacology videos
@mohamedkhyrat7372
@mohamedkhyrat7372 5 ай бұрын
Thank you so much for everything❤
@fallenangel8785
@fallenangel8785 Жыл бұрын
you are a great human being
@katarinatysse6086
@katarinatysse6086 10 ай бұрын
Thank you so much!!
@emacroitor1053
@emacroitor1053 Жыл бұрын
thank you for your help! I am grateful! 😇
@monkearmy2216
@monkearmy2216 Жыл бұрын
I really like these videos, hope you get more recognition
@ricardor2166
@ricardor2166 11 ай бұрын
Great quality
@kda-2672
@kda-2672 2 ай бұрын
Thank you so much ninja nerd❤ you're a life saver
@sangsenglay9989
@sangsenglay9989 Жыл бұрын
thank you so much sir, may god bless u
@mariakara4848
@mariakara4848 8 ай бұрын
the best teacher ever🌹
@malikihamski4265
@malikihamski4265 Жыл бұрын
Sir I appreciate your work Thank you so much A love from TANZANIA.......!
@SH-eh6wx
@SH-eh6wx 4 ай бұрын
God bless you in the ways you do not even imagine!
@robinkaczanowski7970
@robinkaczanowski7970 4 күн бұрын
Love this❤❤❤❤Need more! Excellent Teacher.
@dindaire
@dindaire Жыл бұрын
Omg thank you!! I take my PANCE in a few weeks and your videos are so good
@vetnet100
@vetnet100 Жыл бұрын
Nice video. Helpful and informative
@irereomio1797
@irereomio1797 2 ай бұрын
Love love your videos. Thank you
@rmurthy5011
@rmurthy5011 Жыл бұрын
Very informative. Learnt a lot even as a geriatrics doctor. Perhaps include apomorphine in the drugs? Confess I love your explanation so much I don't want to go back to the books for that!
@hubb4manu
@hubb4manu Жыл бұрын
Thank you so much.
@ladydeebigandcute2681
@ladydeebigandcute2681 Ай бұрын
Let this man open his university ❤
@stephanieslay2976
@stephanieslay2976 25 күн бұрын
I can't thank you enough for this video 🙏 You're just awesome ❤
@ellionorader3219
@ellionorader3219 Жыл бұрын
Thank uuuuu best teacher ever I used to follow You when the channel has some 70k so soproud that you ve reached the M You deserve mooooore
@ahmedfathi3217
@ahmedfathi3217 Жыл бұрын
I love your videos. Definitely one of the best out there. Also, nice glasses 🤓
@laureenl6840
@laureenl6840 Жыл бұрын
Great video! It answered almost all of my questions. The only question remaining is, why is it so important for Parkinson’s disease drugs to be giving at specific times with little to no goodwill time? Does it have to do with the effective time?
@tolika7979
@tolika7979 Жыл бұрын
Hello, I admire your job well done, it is very helpful for all of us! I watch you regularly and learn new things! Thanks! I'm doing a doctorate! I am looking for a connection between impaired understanding of human language, more precisely decoding, in patients with Parkinson's syndrome! What can it be, and where does it come from? Help!!! Be healthy and happy 🙂
@universeusa
@universeusa Жыл бұрын
You are one of a kind 👏👍
@wombat2379
@wombat2379 Жыл бұрын
great job!! Thank YOu!!
@amine6005
@amine6005 Жыл бұрын
You are the best of all the time in saving med students life we are craving for more pharmacology
@armelagjini
@armelagjini Жыл бұрын
you are the best! god bless you
@chipochuumpu6602
@chipochuumpu6602 9 ай бұрын
Thank you!
@oscarpaz6162
@oscarpaz6162 2 ай бұрын
thank u so much for this video zach 🥰
@ranlove47
@ranlove47 Жыл бұрын
As always another great video. Wife recently diagnosed with Parkinson’s. Been doin a deep dive into high does of B1 (thiamine) for treatment. After adding it to the treatment made a huge improvement over the meds (Rytary $$$$$). Would love to see a deep dive into why/how this mechanism might work. Most doctors don’t know or haven’t heard of this treatment. Obviously no money to be made on a vitamin. Thanks again for you dedication.
@steveh1460
@steveh1460 Жыл бұрын
That would be a great topic to cover!
@kirandeepkaur6265
@kirandeepkaur6265 2 ай бұрын
Great teaching process👍🏻👍🏻👍🏻👍🏻
@iulianaandra9699
@iulianaandra9699 Жыл бұрын
Thank you!❤
@goosey1055
@goosey1055 5 ай бұрын
Excellent video.
@maalusn934
@maalusn934 10 ай бұрын
Thank you so much❤
@ashutoshsahoo1013
@ashutoshsahoo1013 8 ай бұрын
Finally All concept clear 😌Salute to your Passion and Strength. Love from Odisha.
@mohsward4708
@mohsward4708 Жыл бұрын
just superb
@jesuschaudhary5458
@jesuschaudhary5458 Ай бұрын
Really amazing ❤❤!!
@buombothmut
@buombothmut 6 ай бұрын
A great scientist ever❤
@nidallkl8559
@nidallkl8559 Жыл бұрын
keep doing this thank youu helps a looot
@banub3111
@banub3111 Жыл бұрын
Thank you ❤
@obvankinndy7063
@obvankinndy7063 Жыл бұрын
Antiparkinson's drugs and hypnotics vids are on time, if only the antipsychotic drugs are on the list it would have been just geeat
@solomebihon2218
@solomebihon2218 8 ай бұрын
you are great God bless you the best teacher ever am medical student in east Africa Ethiopia
@hilinatakele5021
@hilinatakele5021 4 ай бұрын
Thank you so much
@user-hq2xw3dp7f
@user-hq2xw3dp7f Жыл бұрын
Thank you so much ❤❤❤❤
@Gandalf-DZ
@Gandalf-DZ 11 ай бұрын
Gotta love this dude
@virginiabruno624
@virginiabruno624 Жыл бұрын
You are intelligent you go deep into it
@moloreanm1657
@moloreanm1657 Жыл бұрын
Nice vid! Now one about Huntington’s 😊
@NishitaKinger-hr4ec
@NishitaKinger-hr4ec 5 ай бұрын
Great Work!
@johntom2362
@johntom2362 7 ай бұрын
Thank you sir
@mrsamandabernier
@mrsamandabernier Жыл бұрын
Amazing 👏
@zainabfarooq5263
@zainabfarooq5263 Жыл бұрын
I comment for you before I watch the lesson because I’m sure you are great
@owaisahmed7653
@owaisahmed7653 Жыл бұрын
outstanding all the time best teacher❤
@norasaf7838
@norasaf7838 Жыл бұрын
The best Ph of medicine
@hosseinnikbakht7732
@hosseinnikbakht7732 Жыл бұрын
Thank you for this lecture.please say us lecture about Multipe sclerosis
@dailydoseofmedicinee
@dailydoseofmedicinee Жыл бұрын
Thanks
@jessicasmith6873
@jessicasmith6873 Жыл бұрын
I remember voting for pharmacology videos many months ago. I don't want to complain but I relied heavily on you to passing anatomy and now that I'm in pharmacology I'm gonna need you to hurry up 😜 . We did Parkinson medications last week 😞
@Abdullah_DS
@Abdullah_DS Ай бұрын
You know Zach that your vids are kind of entertainment!
@PranamyaPednekar
@PranamyaPednekar 2 ай бұрын
thank you so much
@sawantiparang6660
@sawantiparang6660 Жыл бұрын
thanks you sir,,,please upload analgesic also ASAP🙏
@yosun_job
@yosun_job 2 ай бұрын
Thanks doc
@zainabmaan5330
@zainabmaan5330 Жыл бұрын
You are amazing and vibrating
@lucaspreafico7298
@lucaspreafico7298 8 ай бұрын
Thanks a lot for your work! What’s confusing to me is that i thought colinergic neurons were interneurons in the striatum
@michaelibrahim7190
@michaelibrahim7190 2 ай бұрын
The reason i will be a Pharmacist will be bc you exist! You are much loved in England
@ampala-oc3zt
@ampala-oc3zt Жыл бұрын
Perfect
@azielmalili6516
@azielmalili6516 Жыл бұрын
You are a hero
@sumeraqasim7197
@sumeraqasim7197 8 ай бұрын
Please make a video on anyipsychotic and anyidepressants
@deegallarupananda6927
@deegallarupananda6927 Жыл бұрын
Very useful
@karyllemaecaldera4627
@karyllemaecaldera4627 Жыл бұрын
hoping and waiting that you could upload more videos relating to pharmacology
@drravikumar8122
@drravikumar8122 Жыл бұрын
amazing
@zozoabdulkadir9642
@zozoabdulkadir9642 7 ай бұрын
You are amazing ❤
@timwillebrand2001
@timwillebrand2001 3 күн бұрын
amazing video
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