Click 'Show More' for a how-to, as well as skill guide for this heist.
Silent run of Framing Frame, Day 1 - complete with all 9 paintings. This earns the 'Painting Yourself Into a Corner' achievement.
Your first priority when running this job should be to take the cameras offline. This is easily accomplished if you enter through the roof - you can scout the three possible locations for the security office ahead of time, and drop in through the appropriate window. Be aware that if you do not have Cat Burglar, the only window you can drop in without dying is the one with the large exhibit covered in the sheet. Even with Cat Burglar, dropping from the window to the floor will kill you; you can circumvent this by dropping onto one of the statues on display, or onto the dividing wall, depending on which window you're dropping into.
No patrolling guard will ever enter the security office, making it an ideal place to store paintings until you're ready to carry them out, as well as bagged bodies.
There's 2 easy methods for getting the paintings out of the museum. The first is through the bathroom - you can toss them over the hedge outside and they'll never be seen, then ferry them around to the van when you've collected them all. The second is through the front door. This requires you to take out the security guard at the front desk. Beware of patrolling guards walking through the lobby if you choose this method.
There are 7 total guards on this map (someone correct me if I'm wrong) - 5 patrolling, 1 in the security office, and 1 at the front desk. While it's possible to eliminate all 5 patrolling guards and leave the cameras and front desk alone, I find it's easier to contend with 1 (or 2, if you eliminate the desk jockey) patrolling guards than deal with the cameras the entire time.
Required skills: None. This can be done at level 1 with no skills (though it's a LOT harder).
Recommended skills: Cat Burglar - allows easier and more strategic entry into the museum.
Shinobi (Ace) - Because of the high concentration of guards, silent takedowns are nice to have.
Cleaner (Ace) - If you intend to kill the guards, this should be considered essential. Not being able to move the bodies is an almost guaranteed way to fail.
ECM Specialist - Sometimes, a camera will be positioned right in front of the security office. Without this skill, it can be very difficult or impossible to get inside.
ECM Overdrive (Ace) - This is used to get into the security office.
Smooth Talker - This allows you to kill 4 guards instead of 2 without raising the alarm. This is as close to essential as it gets.
Dominator - This allows you to detain a fifth guard, making the heist easier. Note that if you run into two guards at once, you can shoot or melee one, then immediately dominate the second, then answer the pager, and you will not raise the alarm.