Polyol Pathway or Sorbitol Pathway

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Polyol Pathway or Sorbitol Pathway

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Күн бұрын

Polyol pathway is the metabolism of excess glucose into sorbitol. Sorbitol is a monosaccharide having all six carbon alcohol group (polyol). Sorbitol pathway (polyol pathway) partly explains the microvascular complications seen in uncontrolled diabetes mellitus patients. Osmotic activity of sorbitol is partly responsible for the metabolic changes seen in tissue cells leading to diabetic nephropathy, diabetic retinopathy, diabetic neuropathy, premature cataract.
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Пікірлер: 22

@melissaf4891 5 жыл бұрын

Hi dr Mungli, could you one day make a video on a summary of the pathways and how the come into play with each other. please and thank you. you are so amazing, I talk about your videos to anyone who will listen, how you simplify the concepts.

@kawsarahmed2507 3 жыл бұрын

So nice lecture

@jonothancrooks520 4 жыл бұрын

You're a Godsend. Thank you for taking the time to further my education.

@DrMungli 4 жыл бұрын

You are most welcome.

@yasirmohammedali Жыл бұрын

Hello and thank you for the video

@PhilWu-ie5cg 2 ай бұрын

Glucos to Sorbitol using Aldose Reductase Enzyme, do we need to heat them up at 140C?

@kawsarahmed2507 3 жыл бұрын

Does All type of cell cab make sorbitol in normal condition

@adhipmitra Жыл бұрын

Good talk

@shreyagiri694 3 жыл бұрын

Made the topic so much easier to understand! Thanks a lot doc~

@vigneshkumar8036 3 жыл бұрын

Better understanding sir

@diannecastillo15 4 жыл бұрын

You’re amazing! Thank you so much!!! This really helped me out a lot!!! 💯💯💯💯

@mukasacharles7301 6 жыл бұрын

Thank you DR.

@umesh3077 6 жыл бұрын

Always amazing.u took all topics to very high level

@sebastianjara7554 4 жыл бұрын

Thank you!!!! Great video

@nthomy8645 5 жыл бұрын

Thank you doctor!

@Jackoline6 6 жыл бұрын

a further explanation of how the sorbitol excess will create reactive oxygen species will help answer the question why retinopathy, nephropathy, and neuropathy occurs :)

@DrMungli 6 жыл бұрын

Surely, I wanted to keep the video length within 15 minutes. I will make a continued part of this video to explain underlying mechanism how sorbitol leads to diabetic complications. Thanks for the feedback.

@p.s.krishna2242 6 жыл бұрын

Thank u so much sir

@DrMungli 6 жыл бұрын

You are most welcome.

@SehrKhan 5 жыл бұрын

very helpful thank u sir

@aritrakumar5935 5 жыл бұрын

Useless topics

@pickledrick5158 4 жыл бұрын

I would disagree when 11% of the population is already diabetic and nearly 50% of American population already have a degree of metabolic syndrome obesity, insulin resistance, pre diabetes, high blood pressure or fatty liver disease. Your comment is useless.