Especially with no fume hood and what about his chemical waste disposal?

@@gmcenroe scary scary scary dude you are mister Glen. May as well hide under the bed. God forbid you get run over by a car when you walk out of the house😳😳 It could happen🤷🏻‍♂️

@@waltersobchak7275 Well as a professional organic chemist for over 30 years just looking out for his safety. Fortunately never had too "synthesize" acetic anhydride since it is cheaply commercially available.

@@gmcenroe not just an organic chemist but a professional?? Yeah I feel ya player. We used to have to synthesize this in the back of a Pontiac Grand Am with the windows rolled up we had no choice we probably did gallons like this.

@@gmcenroe Glenn I have some phenethylamine surprise drying in the Büchner for later if you wanna come over? Also bring John👍👍

hello, please send me the method, I need acetic anhydride to obtain esters, and your method is the easiest

as a jr chemist I'm confused why is it so restricted ?

@@sgtbrown4273 its the main reagent used to convert opium into heroin

​@@mcpr5971Mostly to convert homebake morphine (from codeine) to heroin. It's a simple process so I suppose it makes sense to restrict access...so more people die from fentanyl overdose.

Sad but very true...

I don't really wanna get political on a chemistry channel, but really, what would be "the proper" way to deal with "druggies and terrorists"?

Thanks! We’re gonna make a video on producing acetyl chloride in the future.

@@THYZOID Thanks for replying! Unfortunatly almost every synthesis for acetyl involves exotic chemicals! Which most people in other countries aren't able to get. If you can determine a synthesis that is relatively otc I would be amazed to see it!

It’s gonna be otc.

@@THYZOID Awesome! Love your channel, It's great that your making hard to obtain chems accessible to the amateur! I will be watching intently!

@@noodlesoup2281 mexican chem ebay? Same place you would order acetic anhydride

It’s cheap and it works for stuff that only requires stirring :D

Right? I love them. But I would like to start supplying your channel with some chemicals and elements. A sort of sponsorship, per say. Are you interested? I could do monthly or bimonthly shipments as I am in the states and it would be costly to send them, but I am definitely willing to supply your channel with random, hard to find and useful chemicals and elements for free. I already do this for around 7 other KZfaq channels, including Poormans Chemist, ReactiveChem, DBX labs, Primordial Soup and a few others. But yeah, if you are interested in allowing me to send your channel free stuff to use in your videos just let me know and we can go from there. 😃

Damn what an offer which I am only glad to accept. If you are willing to do that I am definitely interested :D Let’s get in contact over Reddit. It’s easier (and better) to go from there than to use the KZfaq comment section.

@@THYZOID awesome! I would love to discuss it over reddit. My name on there is the same as on here and I am fairly active in the r/elementcollection community. I am also on vacation, so I am free to talk anytime for the next week. 😃

I’ve seen your nice HUGE element samples there. I’ll hit you up on Reddit now :D

Maybe cetyl- or phenyl acetate

@@THYZOID p-nitrophenyl acetate maybe? Has IRL applications too in things like enzyme kinetics and chemical tagging.

Another viable but highly dangerous route is the ketene process. Unless you know what you are doing and don’t have appropriate safety precautions and PPE you should stay far away from it.

@@THYZOID Yeah, I think Dug`s Lab has one on the ketene process. That`s some nasty fumes you`re generating while heating the acetone though. Setup needs to be close to perfect too. It`s not exactly a project for the novice chemist. Chlorine gases are a little bit easier to handle then running a ketene lamp.

if you have a hot oil bath go for it

i will still run a ketene lamp eventually. But yeah. If you can get AcCl this method here is convenient.

@@THYZOID well and if you cant get AcCl i guess you can make it yourself, if you can get whatever you need to make it, in case you cant, well just make.....

@@melangkoh4184 there´s always a way to make absolutely everything with readily available materials. if it is easy is another question though

@@THYZOID well looks easy when you make it...what would be difficult by your terms?

@@THYZOID lets take the chemical you made in that video..how dangerous was that? what must have gone wrong in order for you to get injured or spiled with that stuff?

you heat until no more liquid comes over. don´t overheat the solid stuff though

@@THYZOID ah ok thanks you ...But in midium this experience take a few hours or days 🙏

@@ayoublaamoum8236 you can finish the distillation in under an hour with the amounts i used

Yes! It must be anhydrous thoug

It’s really easy in my opinion. At least with the equipment I have it was easy

@@THYZOID is dropping of acetyl chloride necessary or I can pour it directly with bit slow

You can pour it in directly but make sure to cool the flask sufficiently so it doesn’t start to boil

@@THYZOID thank you

Neutralized by NaOH solution trough the vacuum adapter maybe?

right bruuhhh

no.... to put it into perspective it will burn even less than ethanol or gasoline. getting it to ignite is not as easy as holding a lighter on it as well.

@@THYZOID ah ok thx.

If it is pure it is clear

watch the video again....

no

English please

What is sodium acetate or acetyl cloruro de acetilo

I’ve read numerous patents on that route. It should definitely work.

won't that cause a secondary dehidration to ketene? (and nobody wants that!)

@@SuperAngelofglory Ekzeme Production requires extremely high temperatures

@@THYZOID Patents aren't always trustworthy though, or they leave out important details. There are also patents that claim Ac2O production from hexametaphosphate and AcOH but nobody seems to have get it to work at this point.

You get another acetate from the sodium acetate and thus the volume will increase. From 1 mol of acetyl chloride (AcCl) you can get 1 mol of acetic acid when it reacts with water. When acetic anhydride (Ac2O) reacts with water you get two mol of acetic acid for each mol of anhydride

USE ACETYL CHLORIDE INSTEAD

grow some giant poppies

Just extract it from opium.

Also even though they are very nasty, if the concentration you are breathing is dangerous, you notice it pretty fast as it's far more irritating than toxic so you have time to run away. Other gases like carbon monoxide, phosgene and hydrogen cyanide are fare more dangerous as they will easily kill you without giving almost any warning sign.

Definetely not mate. I just like collecting toxic stuff.

You ideally add the acetyl chloride before beginning to heat. You want AcCl and acetate to react before heating as you would boil off unreacted acetyl chloride otherwise.

I didn't mean that / My question was when I added acetyl chloride to sodium acetate in the ice bath / What temperature should I not exceed during the addition?

@@user-hp1zx6wu3i just keep it below 30°C....

Thanks

Should be between 95-100%

@@THYZOIDHola

Yes but the ketone route is extremely dangerous

Acetyl chloride isn’t suited for every reaction. Besides that it is a burden to work with

at one of my two local lab shops. you can get them on the web but there they are often overpriced

@@THYZOID Where would you recommend? Especially for one that could include a septum... How much are they at your local shop? (Just for a point of reference)

you use the trihydrate = you don´t get anything or a REALLY bad yield. You do NOT want water to be present. If you use the trihydrate you will need 4 times as much AcCl and 3 out of 4 mol are just wasted creating acetic acid and HCl without any acetic anhydride. just dehydrate the trihydrate before using it by putting it in an oven at 250°C for two hours

​@@THYZOIDat the end of reaction completion the yellow things if come out a few drops with a charred smell to the collecting flask will there be any problem?

@@sagarikahazra9794 just don´t collect them......

@@THYZOID actually I couldn't remove the flask at once and somehow a few drops got mixed with Ac2O pdt. What's that yellow material by the way. Is it charred Ac2O with or something else. Because by smell it's similar to the product.

In Russia it’s illegal because of drug manufacture

heroin

I can´t

Aren´t these the same? Just take the second one

@@THYZOID but in this video sir you use c2h3na02 .

I search sodium acetate anhydrous Google show sodium acetate But than i search sodium acetate it show ch3coona

@@14gamer12 perhaps don’t attempt this synthesis without even basic chemistry knowledge 💀

They are the same my friend.

If you cant figure that out yourself you shouldn’t be making it in the first place. Besides that there are measurements in the video.

@@THYZOID 😂😂

Don’t

​@@THYZOIDwhy? The esterification of morphine with acetic anhydride is not a particularly dangerous reaction to run.

Can you write that comment in english? My translator doesn´t work correctly

Ja

@@THYZOID und das bekommt man einfach so? Ist ja nicht gerade ungefährlich so als Säurechlorid

Das denke ich mir auch aber es gibt darauf derzeit keinerlei Beschränkungen da es nur mit brennbar, ätzend und Achtung deklariert ist. Ich finde da gehört aufgrund der massiven HCl Entwicklung noch ein Totenkopf drauf. Gefährliches Zeug wenn jemand nicht weiß womit er gerade hantiert.

@@THYZOID Ich hätte mir jetzt weniger Sorgen wegen des Stoffes an sich gemacht, da hab ich an der Uni schon mit weitaus schlimmeren gearbeitet. Ich Frage mich eher ob man da nicht auf irgendwelche listen kommt. Ich mein, es wäre ja durchaus eine alternative für Essigsäureanhydrid bzw ein Vorläufer davon, und Essigsäureanhydrid ist ja nicht ohne Grund schwer zugänglich.

Dafür kommt man bestimmt auf listen aber da ich sowieso nichts verbotenes herstelle und aufgrund meiner KZfaq Videos den Verwendungszweck und Verbleib nachweisen kann mache ich mir da eher weniger sorgen.

Firstly the method you described would sadly not work for making Ac2O. Secondly getting acetyl chloride was cheap and easy for me. In the future we are going to explore easier methods to make Ac2O

You can make acetyl chloride from benzoyl chloride and acetate. Benzoyl chloride isn't that hard to get.

What is salt vinegar, what is hydraulic acid, what is "acetolation of salt"?

no

@@THYZOID you have one of required ingredients....

Which has multiple other uses besides making drugs

​@@THYZOIDif by that you mean making aspirin I want to remind you that acetylsalicylic acid is a drug too.