Primary hemostasis | Advanced hematologic system physiology | Health & Medicine | Khan Academy

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khanacademymedicine

Күн бұрын

During primary hemostasis, a platelet plug is formed to rapidly stop the initial bleeding after injury. Learn about the different steps involved in primary hemostasis: vasoconstriction, platelet adhesion, activation and degranulation, platelet aggregation. Created by Gricelda Gomez.
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Пікірлер: 84
@MonnieMoo318
@MonnieMoo318 9 жыл бұрын
THIS VIDEO IS ABSOLUTELY AMAZING!!!! I actually am understanding!! :D THANK YOU KHAN ACADEMY!! :D
@jmoney8630
@jmoney8630 5 жыл бұрын
I don't know why people are complaining about the voice over. I thought it was perfect. She was talking like an actual person does when they are talking to you. And personally, that helps me listen better. Would people rather it be completely monotone? To each their own I suppose.
@mohamedjatte9145
@mohamedjatte9145 23 күн бұрын
Thank you for your simple explanation
@majedsaeedy1910
@majedsaeedy1910 2 жыл бұрын
Amazing explanation, clear and informative diagrams. I was watching a lecture at my university and didn't really understand primary hemostasis, but this video really cleared it up.
@safirazed7375
@safirazed7375 10 жыл бұрын
Awesome! Thank you so much!
@ALIMAX20072
@ALIMAX20072 9 жыл бұрын
i wish u were my professor :(
@naidoi1
@naidoi1 9 жыл бұрын
I absolutely love khansacademy ☺️☺️☺️
@LD-jp3iu
@LD-jp3iu 7 жыл бұрын
Great explanation. Really helped explain the details of primary hemostasis from First Aid 2017
@tonyejack2069
@tonyejack2069 7 жыл бұрын
i love this video thanks!!!!
@minhlucnguyen7614
@minhlucnguyen7614 4 жыл бұрын
Thank you so much for blowing up my mind, this video is super amazing and easy to be understood!!!!
@ahmedgamaleldeen8451
@ahmedgamaleldeen8451 9 жыл бұрын
Excellent !
@user-uu3xy5ri1p
@user-uu3xy5ri1p 5 жыл бұрын
thank you khan academy, for helping me with almost every exam TT
@cormacdoyle3435
@cormacdoyle3435 6 жыл бұрын
This video is so helpful, thank you
@noorabd5691
@noorabd5691 5 жыл бұрын
Really thank u... God bless ya❤️❤️
@a.s.america
@a.s.america 7 жыл бұрын
great! i almost got it! thank you
@maryannekastner
@maryannekastner 9 жыл бұрын
great video!!
@rahmiaziza4698
@rahmiaziza4698 4 жыл бұрын
this is really helpful! thanks a lot 😊
@demonskwirl9462
@demonskwirl9462 2 жыл бұрын
this is outstanding. very concise, understandable, easy to remember
@PinkPeony21
@PinkPeony21 9 жыл бұрын
Fantastic video! Thanks
@user-zz1qd1pe7l
@user-zz1qd1pe7l 2 жыл бұрын
Great explanation. Thank you!
@asmahaque8558
@asmahaque8558 4 жыл бұрын
YOU ARE BRILLIANT!
@yashika5006
@yashika5006 6 жыл бұрын
These are really helpful......thank you
@sarajade1322
@sarajade1322 7 жыл бұрын
great work ..
@fanvd
@fanvd 8 жыл бұрын
thank you!
@unrivaled37
@unrivaled37 9 жыл бұрын
Thankyou!
@pitiful_sentence
@pitiful_sentence 7 жыл бұрын
THANK YOU!!!
@mrcharlesjohnson
@mrcharlesjohnson 5 жыл бұрын
Str8 fantastic video thnx so much for explaining this in a simple manner
@nativedamascus8819
@nativedamascus8819 5 жыл бұрын
Great work thank you
@nikolaoskormpis3511
@nikolaoskormpis3511 3 жыл бұрын
Really good explanation, thank you
@michaelgilman4068
@michaelgilman4068 3 жыл бұрын
Thanks pretty darn good overview. My Lippincott Pharmacology text fills in some details but your narration and illustration make the concepts and substances a bit easier to latch on to...One small note of criticism, meant constructively, the "hole" in the vessel is called the lumen.
@mohamedalimegahedahmedrash3822
@mohamedalimegahedahmedrash3822 7 жыл бұрын
THANK YOU
@bahiachibi895
@bahiachibi895 2 жыл бұрын
Wonderful amazing thanks
@reemalhazza4868
@reemalhazza4868 4 жыл бұрын
Thank you and love you 😍
@kv9430
@kv9430 3 жыл бұрын
thank you for your sharing ms, this is best, i really analyze the process of primary hemostasis, thank you, i hope for you response 😇
@nadeemrabi647
@nadeemrabi647 8 жыл бұрын
I love you !
@nazmaahmed1544
@nazmaahmed1544 7 жыл бұрын
Thank you
@gangsardamai8139
@gangsardamai8139 4 жыл бұрын
thankzz
@tahirakhtarvlogs5637
@tahirakhtarvlogs5637 4 жыл бұрын
Thank you 🙏
@1412Z
@1412Z 2 жыл бұрын
thank you! very helpful video, i recommend also watching the 2ndary hemostasis video by Khan Academy
@hudapediatric3492
@hudapediatric3492 8 жыл бұрын
nice helpful vedio thanks alot
@mandisangema2568
@mandisangema2568 3 жыл бұрын
You saying fibrinogen leads to platelet aggregation? Doesnt have to be cleaved to fibrin by thrombin first?
@mikeearls126
@mikeearls126 2 жыл бұрын
its cool to learn here definitely....but the high speed video and high speed talking of a person who knows everything about the topic makes learning harder (have to constantly stop video) teaching is not just spewing out stuff as fast has humanly possible....but actually considering who is watching....of course IMHO
@MrShishpal
@MrShishpal 3 жыл бұрын
Great information
@rubaali7886
@rubaali7886 Жыл бұрын
I can be clear with u guys I wouldn't make it through one day before exam without u 😭🙏
@alaaelshiekh3064
@alaaelshiekh3064 6 жыл бұрын
great vedio
@kaelashawa8305
@kaelashawa8305 7 жыл бұрын
thankyou
@amna7629
@amna7629 5 ай бұрын
Gorgeous 🤝🏻✨
@lovely-zg6di
@lovely-zg6di 5 жыл бұрын
y are amazing tnx
@abrardesrt
@abrardesrt 6 ай бұрын
pravo... thx thx thx ❤❤❤❤❤
@jowanismail1942
@jowanismail1942 4 жыл бұрын
Nice one 💕
@AIJ101
@AIJ101 3 жыл бұрын
Great video however I'm not an engineer but if a bridge falls out or half of it does it would be common sense that you don't use the bridge because the integrity of the bridge is no longer intact
@blackyrocky7438
@blackyrocky7438 3 жыл бұрын
First response to vascular injury is vascular spasm or vasoconstriction to reduce bleeding. Then platelet plug, aggregation, and thrombus form. Injured or damaged endothelial cells release endothelin which will act on smooth muscles to contract and ultimate goal will be vascular spasm. Particularly endothelin will trigger release of calcium in smooth muscles which will cause contraction
@leopoldoansantos
@leopoldoansantos 5 жыл бұрын
Great, thank you! What is the name of this software?
@alexcoreablecoreable
@alexcoreablecoreable 7 жыл бұрын
for the last part of this video, isn't it fibrin instead of fibrinogen? i thought fibrinogen needs to be converted to fibrin and then it can form cross-linked mesh?
@nbgoodiscore1303
@nbgoodiscore1303 5 жыл бұрын
I know I'm late but fibrin only exists in secondary hemostasis.
@GigglrTv
@GigglrTv 7 жыл бұрын
Hey, do u com(ment) here often?
@sharonzell2308
@sharonzell2308 8 жыл бұрын
I can get sound on other videos but not the primary and secondary hemostasis?
@sofiajadez7126
@sofiajadez7126 5 жыл бұрын
thank you!!!!
@priyankamidha5071
@priyankamidha5071 4 жыл бұрын
Thank you so much, amazing video. I have a question if someone can help me with it - When an injury occurs, why do we only lose NO and prostacyclin (vasodilators) with the blood and not the vasoconstrictor, endothelin?
@rahmiaziza4698
@rahmiaziza4698 4 жыл бұрын
because the winner is endothelin :) I mean like vasoconstrictor more stronger while injured, so the vasodilators gonna fail with it. Hope it's gonna help u,guys😊
@laboniroy-ed8qp
@laboniroy-ed8qp Жыл бұрын
Best
@sandervdcp3513
@sandervdcp3513 2 жыл бұрын
what is the program for the drawings?
@davidt8274
@davidt8274 8 жыл бұрын
The alpha granules contain fibronectin, not fibrinogen - fibrinogen itself has to be activated by thrombin to become FIBRIN and is stickier - it polymerises with other fibrins and stuff, and only binds to fibronectin when mediated by factor VIII. Fibronectin... don't polymerise, they bind to fibrin when Factor VIII comes into play and catalyse the process (factor VIII stabilises fibrin and 'contracts' it, closing up wounds), Fibronectin mainly binds cell membranes through connecting with integrin molecules, which means it binds cells to cells. Platelets basically start working on long term healing the moment the are activated, but is relatively inefficient until fibroblast cells come in and form huge amounts of connective tissue etc.
@sofiamosca2714
@sofiamosca2714 6 жыл бұрын
Alpha granules contain both: fibronectin AND fibrinogen
@firstnamelastname5474
@firstnamelastname5474 3 жыл бұрын
They have both, actually.
@gabrielsanchez8501
@gabrielsanchez8501 7 жыл бұрын
Fibrinogen is produced by the liver. I think you meant to say "Fibronectin".
@Dr.Ankesh
@Dr.Ankesh 7 жыл бұрын
fibrinogen and fibronectin both are present in alpha granules of platelets
@micahrapata5085
@micahrapata5085 8 жыл бұрын
So just to clarify, does fibrinogen not fibrin aggregate platelets via their activated 2b/3a receptors?
@mohammedabdullah5989
@mohammedabdullah5989 2 жыл бұрын
Fibrinogen aggregates the platelets via their receptors. Fibrin is formed from fibrinogen by thrombin.
@dhooy7150
@dhooy7150 8 жыл бұрын
I don't understand the purpose if vasoconstriction as a result of damage to collagen. Wouldn't this cause more blood to be lost?
@AssassinNasa16
@AssassinNasa16 8 жыл бұрын
Vasoconstriction will increase the flow resistance therefore reducing the flow of blood to the wound site.
@jannasalam
@jannasalam 7 жыл бұрын
the content is good but the voice over is so poor!
@abdullahmohammad6803
@abdullahmohammad6803 6 ай бұрын
No its not
@lisadonayre6654
@lisadonayre6654 6 жыл бұрын
The voiceover/dictation of the topic is SO distracting... still, helpful information..
@muriellejean-baptiste7511
@muriellejean-baptiste7511 9 жыл бұрын
too fast, too fast! lol but still helpful
@ramzehythmoni1777
@ramzehythmoni1777 6 жыл бұрын
I think ..stop saying that .. Plz .
@graciechandlee8879
@graciechandlee8879 8 жыл бұрын
your constant pausing in your sentences is killing me.
@alaaelshiekh3064
@alaaelshiekh3064 6 жыл бұрын
no she is cute u fuck
@Mrscarfire1
@Mrscarfire1 6 жыл бұрын
It is a very good video but please, please, please stop moving the cursor around when you are not writing! You wiggle it around and shake it constantly, it is distracting and annoying. I would quit watching this video except it was assigned by my instructor.
@anglcasncn
@anglcasncn 6 жыл бұрын
You're so hard to understand it makes me sleepy. Prolly because of how you talk. But thanks for the effort
@BrunaNathaly
@BrunaNathaly 8 жыл бұрын
thank you!
@Marlencheeen
@Marlencheeen 7 жыл бұрын
very good job !!!
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