A description of how the DLCO (diffusing capacity of carbon monoxide) is measured, and how it is used in the diagnosis of various forms of lung disease.
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@DoctorKnowDoctorKnow8 жыл бұрын
Saw your videos before a major exam...sometimes repeated them 3 or 4 times...took my test on PFTs and got a 100%....Your Video's Saved Me...
@StrongMed8 жыл бұрын
+DoctorKnow956 DoctorKnow956 I'm glad the videos helped you out!
@nickgowen77374 жыл бұрын
Great job as usual Eric. I am continuously amazed at how well you explain these concepts.
@gerryzavorsky8 жыл бұрын
At 2:37, where the instructor mentions that the DLCO is a measurement of the overall function of the alveolar-capillary membrane, this is technically is incorrect. The overall function of the alveolar-capillary membrane is DmCO, which is alveolar-membrane diffusing capacity. The Roughton and Forster equation states that 1/DLCO = 1/DmCO + 1/(thetaCO x Vc), which is the total resistance to CO transfer is equally divided into membrane resistance and red cell resistance. Thus, DLCO is a function of both alveolar-membrane diffusing capacity (DmCO, mL/min/mmHg), and the hemoglobin concentration (ThetaCO) and the pulmonary capillary blood volume (mL). ALL these things represent DLCO.
@sunving4 жыл бұрын
Thank you Dr Eric Strong. I may need to watch again to understand but as yet this might not relevant to me much since it hardly be ordered this test either.
@dionnawalton60698 жыл бұрын
Hello Brian. Thank You so much for responding to my question. Now it makes sice why the it affects the DLCO.
@AnomiEj3 жыл бұрын
Great video as always Dr. Strong! At 8:51 I would add that DLCO is used when considering surgical treatment of lung cancer (in conjunction with FEV1).
@davidzane33729 жыл бұрын
I appreciate your lectures very much. You mention that DLCO may be decreased with anemia and increased with polycythemia. Later you mention DLCO may be adjusted downward for anemia and upwards for polycythemia. I looked at abstract of Am J Respir Crit Care Med, 1997 Jan: 155 (1). 236-41 which notes DLCO may be adjusted upward for anemia. I thank you for any clarification. I'm likely not seeing something clearly. Thank you again for your efforts. I really appreciate your lectures.
@AshishSharma-bb7or3 жыл бұрын
I hope I'm interpretating this correctly - the slides refer to adjustment of 'predicted' DLCO, ie, the expected *reference* range which is patient specific. So if the patient is anemic, then the reference range/value for that specific patient will be adjusted downward and the observed DLCO value will be compared to this reference value instead of a one-size-fits-all sort of value.
@Suzan_Baddar8 жыл бұрын
Thank you Sir, it is a great presentaion, very simple and clear
@sanjd68824 жыл бұрын
Very nice video. Thank you. Would have been helpful to explain reasons for any discordance with AAO2 gradient.
@drsabitayograj45712 жыл бұрын
wonderful videos,well explained
@sunving3 жыл бұрын
Thank you Dr Strong
@MOhamedFAthi8710 жыл бұрын
جزاك الله خيرا
@rxx30813 жыл бұрын
Great video, thank you so much!!
@johnheathcote90328 жыл бұрын
Thank you for placing your presentations under the creative commons license noted.
@2100zain Жыл бұрын
Thank you that was very helpful
@afnanalnajar8653 ай бұрын
thanks!
@dianagae30249 жыл бұрын
very good explanations
@jkahn535010 жыл бұрын
Really, really useful, thank you.
@farisalshboul99810 жыл бұрын
you are genius sir , may the GOD preserve u :)
@MrSkaja001 Жыл бұрын
Marvelous
@ramshaarshad88233 жыл бұрын
THANK YOU
@ianwalker63783 жыл бұрын
You list Pulmonary HTN as a cause of Low DLCO, but I don't see how that fits into Fick's Law of Diffusion. By itself PHTN doesnt change partial pressure gradient, the thickness of membrane or surface area. Is this association due to chronic damage to the pulmonary vasculature due to PHTN?
@sarikab58452 жыл бұрын
Sir my DLCO is 40 is there any thing to worry please reply 🙏
@StrongMed2 жыл бұрын
I'm very sorry, but unfortunately I cannot give specific, individualized medical advice on here. I recommend speaking with the physician who ordered the test for you about your concerns.
@shoger89 жыл бұрын
So helpful Thanks
@poojapatwal65257 жыл бұрын
Thank you so much
@ryuhyobosa246510 жыл бұрын
hello sir. would please in the future lectures use the pointer in explanation the slides and please use the light background instead the blue one because its more comfortable to the eye.
@StrongMed10 жыл бұрын
Ryu, thanks for the feedback. I know that many on-line educational videos (e.g. Khan Academy) use a pointer function during their video capture. I use different software for my videos (Adobe Premeire), which I think allows for greater readability and versatility, but unfortunately, does not have a pointer available. Regarding the background, I try to mix up the background colors such that each topic gets its own color scheme (chest X-rays are white on black, electrolytes are black on light blue, antibiotics are dark brown on beige, etc...) I understand that some viewers may have different preferences than my choices. For consistency, I'm planning on sticking with current color schemes when completing unfinished series (e.g. video #5 of PFTs, videos #8-10 of CXRs), but will consider your comment when starting new series in the future.
@kkarantanou6 жыл бұрын
6:29 when you refer to low lung volumes you mean ERV,IRV,TV and not RV? because in the case of Pseudorestrictive ERV,IRV,TV are reduced but RV is increased. In this case what should be done with DLCO adjustment?
@lizasandilands60544 жыл бұрын
Hi there, may I use this video in our training material for the company, or where can I purchase it. We train employees what the effects of CO gas are and how it works
@hereiswherethereisnt8 жыл бұрын
excellent
@Mohanj8377710 жыл бұрын
Excellent talk.. thank you
@twominuteanaesthesia2 ай бұрын
Interesting
@ryuhyobosa246510 жыл бұрын
hello sir, l wish u to be in good heath and ask the God to help u in your hard fantastic work. May i ask u where can i find lesson about FIO2 and Base deficient. regards
@StrongMed10 жыл бұрын
Ryu, in the ABG interpretation playlist, there is a video entitled "Effect of supplemental oxygen" - I think it's lesson 17. I generally don't use, or recommend use, of the base deficit, but a brief discussion of it is in a video, also in the ABG playlist, entitled "Alternate approaches to acid base analysis (Lesson 15)" at 6:45.
@facebook67716 жыл бұрын
Why is dlco increased in obesity, and during morning
@reemaz10242 ай бұрын
Love your vids but the intro music u use makes me anxious
@MyCold12 жыл бұрын
I had a PLCO test recently with 88% of predicted.....is that any good?
@StrongMed2 жыл бұрын
I'm sorry but I can't offer specific, individualized medical advice here. However, I will say that one can't conclude anything from a DLCO alone - it only helps with diagnosis or prognosis in the presence of additional data (e.g. lung volumes, spirometry, etc...)
@dionnawalton60698 жыл бұрын
hello. how exactly does Pulmonary HTN effect DLCO?
@bswgd88 жыл бұрын
+Dionna Walton Pulmonary HTN leads acutely to pulmonary edema due to increased hydrostatic pressure in the pulmonary vasculature which will inhibit diffusion, and chronically leads to thickened vascular walls which further limits the gas diffusion.
@memescometrue882 жыл бұрын
🧬
@ryuhyobosa246510 жыл бұрын
hello sir we don't have lesson 5 in PFTs. regards.
@StrongMed10 жыл бұрын
Ryu, I'm sorry I haven't completed this yet. I'm working on several series in overlapping fashion (so that subscribers who aren't interested in a specific topic don't need to wait too long for something that they might be interested in). I've got a couple of other videos in the works ahead of the last PFT lesson, but it's still coming! Thanks for watching!