Dr. Ohsumi, a lot of people in the world now benefits good health freely because of your 30yrs study of Autophagy. Thank you very much sir. God bless you more!

I started autophagy and started eating healthy 3 months ago. Now I am no longer diabetic, no high blood pressure, and cancer-free. Also, lost weight (A total plus). My skin improved tremendously

He's a humble genius and represents the best part of what it means to be a human. That's what I have to say about Mr. Ohsumi.

He is in his 70s and yet he looks young and mentally alert. His skin has a glow of a young person. That is so awesome!

Yes, born 1945 world war ii was over. In japan really hard time to get food. Mom got TB and she stayed in bed for a long time - really hard time to get enough food. That time all people were poor in Japan. Everyone overcome those problems. Yes, i know about Noble prize. I was not so healthy boy, dream was to become a scientist. My father was working at the University. Not so far from University. I wanted to be a scientist. One point, I didn’t want to be in a competitive field. When i started in vacole not many people were working on that subject. That was very good for me. I wasn’t confident and not many people were working in that field. I might not do it now as many people are working on autophagy. Okay, for me i want to understand how cell is dynamic. Actually life is adjustable ..... not so many people interested in degradation. lots of people work on ... not so many on the degradation. Degradation is important. The function of the degradation process. For me, degradation must be equally important. Function of the degradation process. Almost every function of the body has degradation . Important for me autophagy so important for the cell. We only know 30% understanding of autophagy and been working on it 30 years. Autophagy is not so long history. That’s my feeling on autophagy I always showed the slide how the body makes 200 grams protein a day. But we take 70-80 grams from food. Two figures tells us that new protein comes .... important to understand. So ya, for me surprising fact all protein is replaced every two or 3 months. All protein in body replaced. Life is maintained. These days, many many casts or company or newspapers sold many people ... already 3-4 years situation happen for me. So noisy. Hard to say, several people say you will have this in 2-3 years. I not think about that. Took 3 years to publish paper. I wanted to publish 2 papers but not a good way. Took a long time for me. Something new , take that long. Probably as i said autophagy so basic a function of the cell to understand the cell or our body. Autophagy must be involved in many things. Autophagy is involved in so mnay things. Reason my work autophagy in yeast cells.... dissect yeast .... most important cell first genes. Understand autophagy. Autophagy genes in plants and showed ... not so easy to analyze... still difficult... ag genes... research you can analyze autophagy by ag genes. Completely changed research all over the world. Everyone started studying autophagy. Finding the discovery of the ag genes most important. Sorry. Hum. Still okay. Many people interested in autophagy for disease and health problems. I think it is quite reasonable. Degredation is important. Cells should be maintained clean. Very important for our cells. Autophagy one function is recycle cell... eliminates harmful material in the cell. Those kind must be very important to cells and diseases. Still don’t have special medicine to regulate autophagy but might be New science. Probably not familiar. Hum. Okay. For me, so hum. What should I say. Yeah, of course we have many serious problems. Each people have their own serious problems... important... learn a lot how our body working . How whole body is organized. Yeast cell is simple one cell. Still we have many problems to solve. Every cell has a different function. Important to know how cell communication with each other. Every cell has its autophagy function. Own cell autophagy might be the problem. How different cells have different function. Important....some simple... autophagy might not help some people’s health. We need more work on autophagy how it’s regulation in every cell in our body. Okay. I am already quite old. I don’t know how long i will continue my work. I want to have a really good measuring.... what is degradation and how much extent autophagy does in that cell. I want to have biochemistry to just use yeast cell. Improve our knowledge of how it works in Our body *********************I missed a little but maybe it will help you understand better what he is saying ************He discovered at least 15 genes involved with controlling autophagy in the yeast cell.

Such a beautiful position he takes throughout the interview, that of a Nobel prize winner but always open to learn and have his position from studies and papers challenged. What a truly humble and a beautiful human being and a scientist is Mr. Yoshinori Ohsumi ❤️

The greatest amongst us are the most humble.🙏

It's a privilege to listen to him in one to one. He is a great achiever still humble. Thanx for organising it....

I watched this twice, second time with closed captioning, which was a huge help. This was a very important interview from a great man, and I wanted to understand and soak in everything he said. His quote at the end says it all about him and his accomplishments, something we can all learn from if we want to achieve any level of greatness in our lives. After achieving the highest honor in his field, this is his response, that all that has done was to open so many more questions. Words to live by. What an incredible man. For his achievements he is very humble because his focus is on his work, not himself. This was much more than an interview on the authority on autophagy. This was what greatness truly is, something we can all learn from. Thank you so very much for this interview and video.

Dr. Yoshinori Ohsumi rocks! Love, love his contributions to the body of human knowledge.....

Brilliant discovery ! Was terrified to go on fast because of prediabetes. Now I’m 36 hrs fasting and on my way to cleaning out the garbage cells.

Kind of wish the interview was in his native language and we had subtitles so he could articulate what he is saying better.

What an honor to hear Dr. Ohsumi speak about his life’s work and what drove his research! So gracious and thoughtful in his answers. Thank you Naomi! ❤️

For me it was a healing experience to watch this tender woman interviewing this humble genius, the synergy of the to of them heals me.

Thank you Naomi for sharing this amazing interview with us. Very inspiring. ❤️

What a gentle man. He is a great thinker and genius. Humble and kind.

Learning about ketones and autophagy just recently has totally changed my health. I am inspired by his work and I thank him and you for presenting him to me! Thanks, Naomi!

It was awesome to listen Autophagy from its discoverer. Good luck to him in his future work. I have so much respect for him 🙏

What an amazing man! His dedication to this complicated area of cell life and its impact is somewhat mind boggling. Like he said his work over these many years has uncovered a small part of understanding the degradation process, and now so many more questions have arisen. He is so humble. I loved watching him formulate his answers. What an amazing mind! Thank you so much for sharing this interview.

So refreshing to see such a humble genius who is worthy of praise. You can see he dont feel he deserves all this attention he dont seem to want it. Which is so amazing bc so many who have no talent no brains recieve so much attention and they eat it to right up and are the opposite not humble.

What a humble man!

Big pharma must hate this bloke...ain't no money in autophagy.

I don't know why but watching this interview makes me very emotional.

What a lovely gentle man. Glad I started being involved in fasting and autophagy about 5 years ago as well as time restricted eating. Problem is the people who would benefit the most from improving autophagy consider the whole field esoteric and for the fanatical few

what a gracious gentleman. He answered your well thought out questions in ways we could all understand. The most important thing I took out of this, is not to worry about fasting destroying our muscles, as our body will make the protein it needs to maintain them through Autophagy by using up all those degrading cells!

OH!! THANKS SO MUCH FOR THE INTERVIEW 👍

Congratulations, this term autophagy was just very new to me and I try to share as much as I can. Thank you for bringing this to us.

What a Noble Man.. Really Wonderful Thoughts of Dr. Oshumi.. Love you Sir 🙏🙏👍👍💕

Great interview. A lot of class on the part of both individuals.

Dear Naomi, I stumbled over this video one year too late but what a pleasure to see it. More than the content and the interviewee (who is very distinguished of course), the clip is enriched by your interviewing style, personal charm and demeanor. Saying, just in case you find this message in the bottle :-). I am reading your blog now.

Thank you for this interview with this Giant, the shoulders on which all those in the “autophagy arena” stand. What an incredible human. Thank you, Sir. 🙏🏽

beautiful and informative talk , gracias Naomi Mauricio

IT IS A FACT THAT EXAMPLES WORK MORE UPON THE MIND THAN PRECEPTS.I HAVE BEEN FASTING SINCE I WAS YOUNG (A MONTH EVERY YEAR) NOW THE THING IS I AM ALMOST 70 AT THE MOMENT AND STILL I FEEL (BOTH MENTALLY AND PHYSICALLY I AM STILL 25!!!)

The way you set the tone of the interview is amazing. I liked words such as "contrarian."

"We only understand about 30% of the science and working of autophagy", he says. !! That needs to be on a big banner flying across all the vids claiming ANYTHING about autophagy. Enjoyed this video very much.

Naomi, Thank you for the fantastic video.

Fantastic interview. What a lovely man. 🙏

He is a noble scientist ! My humble respects to you sir !

So fascinated I’d love to learn SO much more (reading your book Currently)

Dr. Ohsomi is such an intelligent and beautiful soul. Thank you Naomi for sharing this amazing interview with us 💗

I think she was asking another question before he finished responding. He is capable of much more information than what we got.

So interesting! I am so fond of this gentle man:) I had no idea that most of the protein that our body uses every day is from autophagy, not from our ingested protein.

You are DIVINELY guided and protected 🙏🌹😄

watched it in 2x speed with subtitles not gonna lie... despite that, great interview!

One of the best interview

What a huge debt of gratitude we owe to this beautiful Japanese man. ❤️❤️❤️❤️ Valerie Farrington 🦋🦋

Thank you @Naomi for sharing this amazing interview. Thank you so much Dr. Yoshinori for your great job, saving our life by authophagy.

❤️ Thank You ❤️

Great humble man. His face is so innocent like child. Naomi is also looking smart

Thank you so much

Hopefully in the future, my children (now less than 9yo) interested in learn and research about autophagy.

Thank you for posting! It would be so awesome if you can summarize what he said. It was not easy to understand him. I am fascinated. 😊

I like the way u are talking. U are a great advisor and interviewer.

Two thousand five hundred years ago, the Buddha, experimented with different life styles. Born into royality, he led a luxurious life, but was disillusoned by the suffering of the poor as well as that of the wealthy who suffered because of over indulgence. He thus advcated the middle path, refraining fom starvation , as well as from gluttony, by eating once a day before noon. A pratice that is followed by countless buddhist monks , at the present.

amazing to see how a genius looks and sounds, thank you for sharing!!

I sense the spirit of humor and kindness in his voice.

I am so grateful to you.. I am so thankful to you.. you are Awesome.. Thanks a Billion

Thanks for this live interview! Please let me know how to find a version with subtitles to understand perfectly...Naomi.

21:12: Aww, I think he would have been quite excited to hear more about it, and would probably have some interesting comments on it, if you could have gone into it a bit more. But keeping it on a broad level was probably the best choice. As it's an interview, and not a "reviewing science of autophagy with the initiator of the research on it" -- though that's something that'd be really exciting for me in any case! ^^ 26:45: It's amazing and great that he's still excited to do more of the basic and very essential research of improving the methodology of studying autophagy! Thank you Naomi for conducting this lovely interview! He's such a patient and humble man!

Please note: Dr Ohsumi is a scientist. His work and that of his team that won a Nobel prize, was their identification of genes which made it easier to study autophagy. As of this interview he stated they understood about 30% of autophagy IN YEAST (30 years of work). Mammalian cells (that’s us) are more complex. In this video there was no mention of fasting or a specific diet. No mention was made of any specific way to enhance human autophagy or even if that was desirable. There was mention that in future, it may be possible to develop medication that would control the autophagy processes. Research continues….

I got teary! Thank you so much for this!

Brilliant!! Since it is a rare interview, we really would have liked to understand his words. Good English, just not too understandable. Thank you for adding subtitles soon.

Turn on closed captions. Your welcome.

This is an honor he's a genius I can listen to him for hours I'm so grateful to God for this humble genius man and for Finding this video thank you thank you

What an impressing man. Btw., I like his glasses, too. :-)

Thank you Naomi 😍🌹for sharing this video with a humble but great person for his wonderful work on autophagy. 2 Questions: (1) How many hours before the process of autophagy takes place ? Would a 16/8 intermittent fasting protocol help or do we need a longer period (2) Dr Ohsumi’s comment about protein: does it mean that we should not consume too much protein as it might affect the autophagy process ?

This is just tip of the ice berg.This fasting was a weekly practice in siddha and ayurveda.There will be shockwaves in this world when modern science acknowledges and properly researches about life force energy and bramacharya( advanced version of no fap)

What a lovely interviewer!!

Dear ms whittel... You made me understand why a Belgian man got the title of viscount in 1989. It was Christian de Duve. Recipiant of the Nobel Price of physiology in the seventies for his work on the lysosome and coming up with the term autophagy. Thx for that.

Humble genius

This is how you realize how your BODY IS MORE POWERFUL than you can imagine (not only your Thoughts!)! There is an enzyme in our body that can minimize aging, and is harnessed through the correct meditation and energy exercise (yoga? qi gong?...who knows!). We will wait for the next nobel prize winner to discover this! ;)

Brilliant person best part of human Astonishing research by brilliant scientist

Omg ❤ my favourite guest . Please pronunce it autophagy

Intelligence + humility makes people great!

Thank you Sr for the effor,so we anderstand,,for both,🙏😚😙🙏💞❤💪

Now that i know that hydrogen water activated autophagy, I won't forget drinking it daily.

Genius _rare and so devoted

When I look closely at the radiance of this man, I almost forget that aging is something negative. But my question is: To what extent could autophagy support or eliminate one of the seven points that make up the Aubrey de Gray theory (intracellurar junk)? Does autophagy also clean the collected garbage outside the cell? This last question seems to me to be of central importance for the appearance of a human being (speaks beauty of the skin).

Real genius. 🙏🙏🙏

In India, we have been following fasting methods for thousands of years... But because of religious reasons. In our ancient religious books/ literature/ Vedas, the long water fastings have been given lots of importance. Every where it is mentioned that in a healthy body lives a healthy mind. So when you sit for meditation ( which is way to feel/ meet/ sense the GOD), first you cure/ purifie your body with fasting, so that you could sit easily and concentrate / meditate. I think they entangled fasting with religion so that people would follow it for the sake of GOD if not otherwise.

I read a lot of comments about how much of a genius he is, and while that may be true I’m more interested in what people are taking away from his work in practical day to day applications. 1. That protein synthesis comes from autophagy of our own protein cells. Therefore we must replace that protein through diet, not just for muscle growth but for all the bodies processes that require protein. 2. The way our body synthesizes protein is also the reason why we lose muscle mass if we don’t get enough protein in our diet, as well as poor health due to the organs cell requirements.

Hatts up sir great scientist 🙏🙏🙏

That's basically Kintsugi in biology. Truly fascinating.

Came here for the IF, stayed for the Naomi hotness factor

Important interview however needed a strong introduction and orientation to better grasp the topic.

Could someone clarify what the doctor meant when he spoke about protein?

Great interview! But I wish you had asked him if he himself practices Autophagy to stay younger and healthier.

very rare and good interview.

Nice video

Would it be possible to get a transcript of this interview as I had trouble understanding? Thank you Naomi for sharing this.

🙏 I start already with 72 hours I feel super 🙏

Too difficult to understand. Would love to see a written copy of what he was saying. Thanks for this interview.

Dear Naomi, I would like to know more detail and sample of his recommendation, his diet. I'm in depression and need some way to survived.

30% understanding of autophagy can manage to get Nobel Prize. So the blue ocean is still great benefits to venture and explore.

je ne trouve pas le lien pour le lire en français. S'il te plait Guy, pourrais-tu me dire comment faire ? Merci

How to start autophagi...and how much hours i have to live in fasting situation...what could be taken during autophagi......??? Thankyou.

Hello. I watch this video in 2023

Amazing! Can someone explain more in our everyday language Regards to this interview? Thank you!

He Is my máster, Yoshinori Oshumi! (:.

Does he mention how long he recommends people fast to achieve autophagy?