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The Centers for Medicare & Medicaid Services (CMS) held a webinar in July 2021 on reporting eCQMs using the Fast Healthcare Interoperability Resources® (FHIR®) standard. FHIR is the next generation standard for exchanging healthcare information electronically and the healthcare community is adopting to advance interoperability. CMS is exploring a potential transition to FHIR-based quality measurement and how it can support the sharing of standardized data electronically in clinical settings. This webinar is a technical, advanced-level session for health information technology professionals supporting Eligible Clinicians and Hospitals in reporting CMS eCQMs. This webinar assumes the attendees have prior knowledge of Health Level Seven International® and FHIR terminology and includes: a review of the Quality Measure architecture; a review of the Data Exchange for Quality Measures (DEQM) FHIR Implementation Guide; describes exchange roles and workflow steps; a review data exchange scenarios; and a review measure reporting scenarios.