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“What it's telling us is that Alzheimer's disease is now becoming optional. The bottom line here is that if everyone gets either prevention or early reversal, virtually no one needs to be concerned about this. That's a fundamental change for a major global problem...and reduces your risk to virtually zero. It's a new era with cognition. Our goal is a global reduction in the burden of dementia..” - Dr. Dale Bredesen.
Today’s guest is Dr. Dale Bredesen, Chief Science Officer At Apollo Health and a prodigious innovator in medicine, with over thirty patents to his name. His thirty-plus years of medical research have put Dr. Bredesen at the forefront of research into Alzheimer’s disease prevention and memory-loss reversal. His research and discoveries have changed our understanding of the fundamental nature of Alzheimer’s disease and led to revolutionary treatments.
In this episode, we dig deep into understanding why cognitive decline, Alzheimer's, and other neurodegenerative diseases should be treated with a 21st Century approach, namely through investigating and solving for the cause of the disease, as well as his groundbreaking protocol for reversing cognitive decline at any age, medicine for longevity, and much more!
Additional Resources:
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EPISODE NOTES:
02:33 From the get-go, Dr. Bredesen’s description of a recent clinical trial conducted at Apollo Health introduces us to the crux of his revolutionary approach to cognitive health; recognizing that Alzheimer’s disease is a complex chronic illness with several contributing factors and getting at the root cause of the illness by taking a ‘precision medicine approach’ to each individual.
08:39 What factors contribute to neurodegeneration? Dr. Bredesen discusses the role of factors such as synaptoblastic signaling, inflammation, and insulin resistance and explains how they affect the Alzheimer’s brain.
18:21 Dr. Bredesen outlines why we need to rethink what aging means. How do we tackle cognitive decline? Apollo Health’s PreCODE and ReCODE programs are a great place to start, and Dr. Bredesen even offers a suggestion for a romantic Valentine’s Day!
25:54 Dr. Bredesen tells the story, taken from his new book The First Survivors Of Alzheimer’s, of one woman’s struggles with drug trials and subsequent success in an Apollo Health protocol. How do ineffective drugs still dominate medical funding? And why is it silly to say someone died “of Alzheimer’s”?
40:03 What does the new type of physician who can make progress with neurodegenerative diseases look like? Dr. Bredesen outlines the multi-faceted, integrative approach required for this task.
48:04 Dr. Bredesen recounts his journey into studying neurodegenerative diseases, including pioneering lab work with Nobel-laureate Dr. Stan Prusiner. Is good cognitive health a matter of getting the balance right? And what single book does Dr. Bredesen credit with starting him on his journey toward studying diseases of the brain?
01:09 The true cost of aging badly is brought into stark focus. But a future that includes large datasets, quantified selves, and a global approach to the burden of dementia looks very bright.
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