No video

Rexulti

  Рет қаралды 20,077

wellnowdoctor

wellnowdoctor

Күн бұрын

Rexulti improves symptoms of schizophrenia but is principally advertised as an add-on therapy for lingering symptoms of depression not satisfactorily improved with ongoing antidepressants. Rexulti appears to be a successor to Abilify - another similar atypical antipsychotic drug.
Questions exist regarding the wisdom of prescribing atypical antipsychotic drugs for treatment resistant depression. Weighing the potential benefits against the very real risks of significant harm leads some to doubt any advantage of Rexulti. The drug causes tardive dyskinesia - a movement disorder that typically persists long after discontinuing the drug. It also leads to weight gain, diabetes, increased cholesterol, falls and impulsive behaviors. Both fatal and non-fatal stroke may occur.
The Canadian health authorities appear unimpressed with Rexulti and recommend against its use in typical depression. Similarly a Veterans Administration study demonstrated relatively equivalent results with adding another antidepressant or switching to a different antidepressant.
The cash price for Rexulti exceeds $1100.00 a month compared to less than $25 for the generic versions of Abilify, Zyprexa, Resperdal or Seroquel.

Пікірлер: 88
@WoofYoungFreesoul
@WoofYoungFreesoul 4 жыл бұрын
Idec what side effects rexulti MAY cause. I'm still gonna take it cause as someone with bipolar disorder, this is honest to God the only medicine that's really helped me and I've been on almost everything
@ScaryRevenant
@ScaryRevenant 4 жыл бұрын
jennifer Palumbo it’s an amazing drug
@Mandapanda1987x
@Mandapanda1987x 2 жыл бұрын
Same
@Just_vi2
@Just_vi2 Жыл бұрын
Any side effects? I'm bp2
@SexyFord
@SexyFord Ай бұрын
@@Just_vi2weight gain, makes you tired as well. (My experience)
@sombrance
@sombrance 2 жыл бұрын
Helped me with intrusive thoughts of suicide and self harm. First time in 12 years since I was diagnosed.
@blktegs
@blktegs 11 ай бұрын
Still help?
@jaeshasway
@jaeshasway 4 жыл бұрын
Wow, my doctor gave this to me to take with Cymbalta which was prescribed for Fibromyalgia. I started getting depressed because I lost my job due to slow recovery from obstructive sleep apnea and fibromyalgia. He said that if the depression wasn’t manageable to take rexulti. He gave me a starter pack. I’m glad I saw your video before taking it.
@frankwhite7109
@frankwhite7109 3 жыл бұрын
Tried it with SSRI. Overheating body temperature binge eating insomnia
@brockkanies7001
@brockkanies7001 3 жыл бұрын
I don’t know about the accuracy of what you’re saying but the depth and detail with such fluent delivery gives me have faith in your knowledge. Thank you for such an elaborate explanation and quality video. *Consider having the microphone closer to your mouth*
@holyentropy7800
@holyentropy7800 4 жыл бұрын
You're the best doc.I love to watch your videos :D
@ScaryRevenant
@ScaryRevenant 4 жыл бұрын
Been on this a month it’s an amazing medication however for me it is fairly sedating ( 1mg dose)
@ScaryRevenant
@ScaryRevenant 4 жыл бұрын
Graeme Nunes I love being sedated 👌🏻
@AlonsoLira
@AlonsoLira 2 жыл бұрын
Lord... I appreciate the time and effort you took to try to explain this new compound, but the structure and the linearity of your explanation is anti psychotic prescription-worthy.
@PeppaPicky
@PeppaPicky 2 жыл бұрын
Getting to know how much Rexulti costs in the US is shocking. In Brazil I pay less than 50 USD for a month of the medication.
@ilaVLira
@ilaVLira Жыл бұрын
Você ainda está em tratamento com rexulti? Está gostando?
@PeppaPicky
@PeppaPicky Жыл бұрын
@@ilaVLira Eu gostei bastante, foi muito mais eficiente do que risperidona, mas tive que parar por causa do preço. Agora estou com risperidona, escitalopram e ritalina, após ter o diagnóstico te TDAH + TOC e TAG. Está sendo incrível, me sinto vivo, motivado e feliz pela primeira.
@ilaVLira
@ilaVLira Жыл бұрын
@@PeppaPicky que bom, Pedro. Não sei meu diagnóstico ainda. Talvez seja distimia com ansiedade. Comecei pela primeira vez um tratamento medicamentoso há 25 dias: 10mg de escitalopram e 50mg de quetiapina. Não sei se estou melhorando. Estou pesquisando opções. Acho que o Rexulti pode potencializar o antidepressivo.
@ilaVLira
@ilaVLira Жыл бұрын
@@PeppaPicky você teve algum efeito colateral?
@PeppaPicky
@PeppaPicky Жыл бұрын
@@ilaVLira Que bom que você começou o tratamento, Ila! Minha adaptação ao escitalopram foi muito difícil, piorou muito a ansiedade, mas depois de três meses cheguei na dose adequada para mim e agora tô ótimo. Meu marido tem distimia e respondeu muito rápido ao tratamento (Venlafaxina e Bup). Desejo uma melhora rápida no seu quadro. Nunca desista. A psiquiatria é muito artesanal e é baseada em tentativa e erro, mas quando bem feita ela muda a vida da gente.
@thepudge6953
@thepudge6953 2 жыл бұрын
rexulti was a good drug no cap
@user-fs1jl7zc5v
@user-fs1jl7zc5v 2 жыл бұрын
Many thanks for the thorough video.
@MrDcrules
@MrDcrules 4 жыл бұрын
Fantastic video. thank you!
@wellnowdoctor5976
@wellnowdoctor5976 4 жыл бұрын
Glad you liked it!
@JohnSmith-oh5zp
@JohnSmith-oh5zp 4 жыл бұрын
I experienced fairly significant impulse control issues while on Rexulti and needed to stop the medication. What is the underlying mechanism of this as I know it is an adverse side effect of its close cousin, abilify
@Kris_USA90
@Kris_USA90 8 ай бұрын
Not sure if you're still interested in this, but it's because of the activation that the Dopamine D2 receptor, we'll just heavily involved in pleasure seeking and enjoying activities. Abilify and Rexulti both act as Partial Agonists at this site, unlike almost every other antipsychotic which are D2 antagonists. Antagonists bind to and fully block the action at a receptor site. Agonists Will bind to and stimulate action at receptors similar to the way free floating dopamine well touch that detail receptor and give you the "feel goods". These medications have the Goldilocks Effect because they are partial agonists meaning that they can theoretically lift low dopamine levels and reduce overabundant dopamine levels. They bind to the site and in the presence of low dopamine transmission (depression), will boost dopamine activity in their own right. In high concentrations of free androgenous dopamine floating in the synapse (schizophrenia), you are still getting some activation because the medication is sitting on the receptor and causing some sort of intrinsic activity, but still blocking/reducing levels overall. All that being said, typically it tends to be very balancing for many, but for those sensitive to the acts of dopamine and dopaminergic transmission, in both control and dopaminergic transmission, impulsivity and hedonistic activity can increase. Hope that helps! :)
@yearofthecat5995
@yearofthecat5995 Ай бұрын
Made me feel like uncomfortable and had negative impacts on my eyesight
@corymodzeleski7191
@corymodzeleski7191 4 жыл бұрын
I was on it for 2 years for Schizoaffective disorder. I loved it because it was the only anti-psychotic I've been on that didn't have any side effects on me. But unfortunately it stopped working after a couple years. Now I take Invega, which has it's pros and cons. Do you by chance have a video on Invega?
@Burevestnik9M730
@Burevestnik9M730 3 жыл бұрын
It is interesting that you had a severe akathisia reaction while on Abilify and 2yrs on Rexulti no such reaction although it is supposedly the same chemical formula. What if this drug gives its specific positives only to a subset of patients (like all APs), but who would otherwise have a bad reaction on Abilify (1 in 4 patients on 15mg Abilify ends up in emergency for akathisia). Maybe only those patients are the target for Rexulti: try Abilify first, but severe reaction => try Rexulti. While on Rexulti for 2yrs, what was your LDL, HDL, Total, Triglycerides, HbA1c (ideal HbA1c level is 48mmol/mol (6.5%) or below. If you're at risk of developing type 2 diabetes, your target HbA1c level should be below 42mmol/mol (6%)) at the end of 2yr period?
@corymodzeleski7191
@corymodzeleski7191 3 жыл бұрын
@@Burevestnik9M730 Yeah that is a good possibility.
@Burevestnik9M730
@Burevestnik9M730 2 жыл бұрын
@@corymodzeleski7191 When it stopped working, did you increase the dosage or you were already on the highest dosage?
@Wowzersdude-k5c
@Wowzersdude-k5c 5 жыл бұрын
Damn it Dr. Landow. Just got prescribed Rexalti today and am scared to take it now.
@AlchemyOfInteraction
@AlchemyOfInteraction 2 жыл бұрын
same, any update for us lol
@nancyorkeithm1518
@nancyorkeithm1518 2 жыл бұрын
Thank you! I
@SurgeCess
@SurgeCess 2 жыл бұрын
Help, I just just 0.5mg for the first time (prescribed by a psychiatrist) and I CANNOT stop crying! I am just in a frenzy now, I flushed the rest of the pills down the toilet, I don't know what to do, this is scary
@timcepin3386
@timcepin3386 4 ай бұрын
How long did you take it for?
@kellyjackson5693
@kellyjackson5693 5 жыл бұрын
This medication caused uncommon events of rage. I stopped it after about 2-4 weeks.
@kellyjackson5693
@kellyjackson5693 5 жыл бұрын
@Anthony Supar I experienced feelings of anger and rage on a level that was not customary to my personality while taking this medication. I responded to people around me more aggressively and just overall felt more angry than usual. Also my anger was more difficult to control. This wasn't the intended purpose for the medication so I called my doctor and stopped taking it.
@kellyjackson5693
@kellyjackson5693 5 жыл бұрын
@Anthony Supar In my case, it was prescribed as a mood stablizer in conjuction with an antidepressant, but it didn't work well for me at all.
@kellyjackson5693
@kellyjackson5693 5 жыл бұрын
@Anthony Supar It was crazy! lol It was a bad fit for me it may be different for you. Talk with your doctor right away about any concerns you have. Good luck.
@Burevestnik9M730
@Burevestnik9M730 3 жыл бұрын
This intro "music" is really irritating. How about attenuate it and then whoever longs for it, he can increase the volume?
@DrAdrianRobichaud
@DrAdrianRobichaud Ай бұрын
I stopped it about 6 weeks ago reducing over about two months. I was on Latuda for many years then brexpiprazole for about 6 months. I started getting some blepharospasm and the was one of the reasons I went off of it. I am still getting blepharospasm. Can withdrawal from brexpiprazole cause this?
@shadyelnaggar
@shadyelnaggar Жыл бұрын
I love his voice tone, looks like professor McGonagall
@shericriswell79
@shericriswell79 9 ай бұрын
I just started it, my anxiety is spiking. I'm stopping
@karenm6451
@karenm6451 2 жыл бұрын
I have peptic ulcers is this viable to use
@jamiephillips9239
@jamiephillips9239 3 жыл бұрын
Can you do a video on trileptal?
@dixonyamowthe6087
@dixonyamowthe6087 5 жыл бұрын
I was prescribed this for the low price of $1400 a month. I said hell no.
@rexbenten8309
@rexbenten8309 5 жыл бұрын
My husband's taking 40mg of this. It's been working for him so far. There was an adjustment period though. With our insurance, we pay $15 for a month's supply.
@ScaryRevenant
@ScaryRevenant 4 жыл бұрын
Rex Benten 40 mg ?! 😳 I’m on 1mg and get it from my doctor for free
@tagaway6173
@tagaway6173 3 жыл бұрын
@@rexbenten8309 don't you mean 4mg no 40mg?
@LauraRicarte
@LauraRicarte 7 ай бұрын
Pobably ​@@tagaway6173
@alcam14
@alcam14 4 жыл бұрын
Bad drug in my opinion.
@user-hs3pk4bk5l
@user-hs3pk4bk5l Жыл бұрын
I use this for schizoaffectice disorder. Does anyone have any opinions on Rexulti?
@evacameron8670
@evacameron8670 6 ай бұрын
Rexulti is not Abilify, use Rexulti not Abilify for less side effects. College of Pharmacy UICC, Chicagoland.
@evacameron8670
@evacameron8670 6 ай бұрын
per month Rexulti costs. 1480-dollars 1700 at Walgreens
@rexbenten8309
@rexbenten8309 5 жыл бұрын
Thank you. Have you done a video on Latuda?
@gwenwood4651
@gwenwood4651 5 жыл бұрын
Lutruda did me no good plus you have to eat with it just saying
@gwenwood4651
@gwenwood4651 5 жыл бұрын
Latuda I meant
@TheMsf111
@TheMsf111 4 жыл бұрын
Latuda is the best for me
@markjones5807
@markjones5807 4 жыл бұрын
kzfaq.info/get/bejne/ndSnd6pjpsybZmg.html
@laurenschultz9781
@laurenschultz9781 Жыл бұрын
Wow way to scare people from trying this drug….guess it’s better to just stay depressed 😮
@MaRu-ui3ug
@MaRu-ui3ug Жыл бұрын
Add weed to it. Might as well go all the way. Glory to meds.
@RealtimeReviews613
@RealtimeReviews613 2 жыл бұрын
Terrible drug!!!!! Made me figety, made anxiety worse! Headache since i started taking it. I had to stop it. Just remember everyone is different
@jacob2431992
@jacob2431992 2 жыл бұрын
Did your symptoms go away?
@osamazynladen_
@osamazynladen_ Жыл бұрын
why would you claim it is a terrible drug if you acknowledge that everyone reacts differently?
@JayOh-
@JayOh- 8 ай бұрын
Sounds like side effects
@timcepin3386
@timcepin3386 4 ай бұрын
Me, too. After two doses, too!
@dv_vid
@dv_vid Жыл бұрын
It's just a waste of time and money.
@TheYogimind
@TheYogimind 2 жыл бұрын
This is all complete insanity. Just stay with the depression, sit with it, and see it. Take your time and you can overcome.
@coltonmoore6574
@coltonmoore6574 2 жыл бұрын
That’s like saying Just simply sit with being diabetic, you can overcome.
@PeppaPicky
@PeppaPicky 2 жыл бұрын
This is simply stupid.
@jordandahm9586
@jordandahm9586 Жыл бұрын
I used to be this ignorant as well. Now I'm 32 and was just diagnosed bi-polar after trying to just "deal with it" for 17+ years.
@TheYogimind
@TheYogimind Жыл бұрын
@@jordandahm9586 Trying to help here ok? Do you have any idea what could be causing the bipolar with the up and down mood if that’s what you’re experiencing?
@tofuindulger8087
@tofuindulger8087 Жыл бұрын
@@TheYogimind they’re literally telling you it’s chemical. Just because you don’t have clinical depression or mood swings that deal with hormonal imbalances doesn’t mean they don’t. I’m glad you were able to work out whatever life events that were causing your depression but other people may not be in the same boat and choosing to ignore it because it’s not your experience is ignorant my guy.
Depression The Basics
26:56
wellnowdoctor
Рет қаралды 17 М.
Mirtazapine
23:52
wellnowdoctor
Рет қаралды 126 М.
❌Разве такое возможно? #story
01:00
Кэри Найс
Рет қаралды 3,7 МЛН
Мы сделали гигантские сухарики!  #большаяеда
00:44
WILL IT BURST?
00:31
Natan por Aí
Рет қаралды 28 МЛН
I Took a LUNCHBAR OFF A Poster 🤯 #shorts
00:17
Wian
Рет қаралды 6 МЛН
Everything you NEED to Know about Rexulti (Brexpiprazole)
16:10
Levelheaded Mind
Рет қаралды 10 М.
Klonopin
21:05
wellnowdoctor
Рет қаралды 106 М.
How To Use DOPAMINE As A Superpower To TREAT ADDICTION! | Anna Lembke
1:31:48
Dr Rangan Chatterjee
Рет қаралды 335 М.
How is BREXPIPRAZOLE different from ARIPIPRAZOLE? | Mechanism of action of REXULTI | Dr Rege
14:03
Psychiatry Simplified - Dr Sanil Rege
Рет қаралды 14 М.
What is Schizoaffective Disorder- Is It Worse Than Bipolar Disorder?
9:21
Brexpiprazole/Rexulti is it The New Aripiprazole?
13:39
Shrinks In Sneakers
Рет қаралды 10 М.
Heroin
32:56
wellnowdoctor
Рет қаралды 15 М.
Latuda
34:22
wellnowdoctor
Рет қаралды 28 М.
How to recover from depression
1:02:36
Psychlopaedia.org
Рет қаралды 5 МЛН
❌Разве такое возможно? #story
01:00
Кэри Найс
Рет қаралды 3,7 МЛН