How 10 mins made me understand a whole concept 👏🏻👏🏻👏🏻

This video is so important for Internal Medicine rotations

thank you ver much, i personally prefere fast and short explanations, and u nailed it .

AWESOME> I teach shock to my nursing students and I'm going to watch this with them (says things better than I can in many ways)

Great video! Super helpful! Thank you so much!

This is an excellent beginner's guide to shock ! Thank you!

Excellent overview!! Thank you!

You are a magician...how you clear all concepts in just 10 min😮❤

Thanks sir, such a best video

The best video for shock ❤️❤️❤️

Thank you, much appreciated

You are my life saver!

never seen it that well explained!

ı always understand the mechansims in this channel. thanks a lot from Türkiye !

Awesome 👍

Worth watching ur video

You really explained the whole concept in 10 minutes, thank you very much 🔥❤

Great!

Thank you so much ❤️

DAMN !!you guys are great

Speechless

OMG THANK YOU VERY MUCH 🙏🙏

Thank u😊

Thanks.

Thank you so much 💕💕

Thank you 🙌

Thank you♡

Excellent♡

Thank you so much

So helpful

Pretty amazing

Thank yooooouu❤

Awesome

Thanks

can u.load all.osnosis video

around 7:34- 8:22 - if we have microvasculature blockage - doesn't this increase resistance and therefore make it harder for blood to move around the body? If not why? Is it because blood gets shunted away from the capillaries via collaterals? and I'm assuming this has the added benefit of bypassing tissue perfusion?

They never teach me like this during my college time, i spent 48 month in college, but here just 10min i learned a lot. My point is why should i spend my time for 4years in college if there's a way just only 24hrs i already finished my medical degree in college. It could be a lot of money that i saved in my bank account .

Like genuilyyyy besttttt

How there is increase in blood flow during distributive shock?? As BP in increased?

Can anyone tell from where the content is taken i mean which book

💎

👌👌👌👌🙌🙌🙌🙌

🤩

Bruhh ❤

👍

بسم الله ماشاء الله

How is blood flow increased in distributive shock when blood pressure is decreased ?

Ischemia: lack of blood flow to tissue (circulatory failure) --> lack of oxygen and nutrition --> cellular damage --> organ failure Shock: body-scale ischemia --> multiple organ failure Blood pressure determines perfusion of oxygen and nutrition to tissue Blood pressure = resistance x cardiac output = resistance x (heart rate x stroke volume) = resistance x heart rate x (end diastolic volume - end systolic volume) : low cardiac output --> low blood pressure --> low perfusion + Low blood flow --> low tissue's heat --> cool and clammy skin + Low mixed venous oxygen saturation Regulation (goal: normal perfusion): low cardiac output --> release of catecholamines, ADH and angiotensin II --> vasoconstriction --> increases resistance and heart rate --> increase blood pressure (low-volume-blood) SHOCK 1. Non-hemorrhagic (not-from-bleeding) --> occurs when suffering severe dehydration --> low blood volume --> low stroke volume --> ... 2. Hemorrhagic (from-bleeding): starts when loss of about 1 liter of blood (20%) --> low blood volume --> low stroke volume --> ... (heart-produced-by) SHOCK Trauma (usually heart attack) --> damage of heart muscle cell --> weak contraction --> low stroke volume --> ... Obstruction in heart (fluid or blood in pericardial sac) --> constriction of heart muscle from expanding --> low stroke volume --> ... : low resistance --> low blood pressure --> low distribution to (some) tissues + High blood flow --> high tissue's heat --> warm and flushed skin + Normal or high mixed venous oxygen saturation SHOCK: caused by leaky blood vessels or excessive vasodilation 2 subtypes: anaphylactic shock (allergic reaction) and neurogenic shock (damage of CNS --> can't control blood pressure) Most common: SHOCK (from pathogens in blood): endotoxins --> low perfusion --> direct damage of endothelial cells --> release of vasodilators --> activation of complement pathway --> activation of mast cells --> release of histamine (vasodilator) Pathogens --> activation of macrophages and neutrophils --> release of cytokines --> release of inflammatory molecules by endothelial cells --> damage of endothelial cells (again!) --> leaky blood vessel and more blood clotting --> low perfusion (more!) TREATMENT Goal: stabilize blood pressure --> vital organs can be perfused with blood --> fluid replacement and medications Often: supplemental oxygen and airway protection

💜❤️

1:48 , gave Chubbyemu vibes

Osmosis it is!

🤗👍🙏🙏

Basically, I should be drinking more water.

I want to make some videos on medical topics by collaborating with you... Will u collaborate??

First reaction, shock! Shock bæcaus...

Do uncosiosness

Interpretion of my dad’s immune system

Did you steal the video from osmosis? This video is good but I hope osmosis is nice to you. Give credit to them.

they have dleted

I cant understand

Arabic caption?!

Thank you so much