from all the way in the middle east, precisely Jordan, I want to thank you with all my heart! you helped me through my second physiology exam and now tomorrow is the final one< thank you so much!

"we have no way to control smooth muscle" *morning coffee has entered the chat*

Unlike cardiac or skeletal muscle, smooth muscle is not striated because it does not consist of sarcomeres. Instead, a network of different filaments are found throughout the entire cell body and this helps the cell contract. The three types of filaments are thin filaments, thick filaments and intermediate filaments. Thin filaments are usually connected to regions called dense bodies while the thick filament is found in between thin filaments. The movement of the thick and thin filaments causes the dense bodies to move together, which in turn pulls on the intermediate filaments, which brings all the dense bodies inside the cell closer together. This ultimately causes the cell to shrink and this is known as the muscle contraction. Smooth muscles can be arranged into two ways. We have single-unit smooth muscle, also known as visceral smooth muscle and we also have multi-unit smooth muscle. Single-unit smooth muscles consist of a collection of different smooth muscle cells that are connected via gap junctions. Only a few of these muscles are actually innervated by a neuron. When a signal arrives at the innervated smooth muscle, the gap junctions cause the other cells to contract in a uniform fashion. Therefore, single-unit smooth muscles contract together, as a single unit. These smooth muscles are also capable of myogenic activity. Multi-unit smooth muscle consist of a bundle of smooth muscle cells that are all innervated by a neuron. This means that the contraction of a muscle in a multi-unit system is independent of the contract of some adjacent cell. Smooth muscles are control by the autonomic nervous system and are found in places like blood vessels, stomach, small intestine, uterus, bladder and many other places. Smooth muscles are uninucleated, which means that they have one nucleus per cell.

I don't know how but you always make things simpler and easier THANK YOU SO MUCH!!!

Thank you so much for your lectures, I study, read, re-watch my Professor's lecture and then defer to yours as back up and further foundation for my exams! I really appreciate your ability to clearly explain these extremely complex topics!!

Thanks man, Ive watched a lot of lectures online. But I have to say you are a step ahead of all. You break it down very well and articulate everything nicely, which leaves no doubt for the viewer. Thanks again!

You and the people over at crash course are the sole reason I am coping with a and p and bio xD thanks so much

Why are we paying the colleges? I should make my tuition payable to u!! Thanks for everything man!

You are making the topics easy for us👌🏻thank u for being so helpful for us. I really abhore the dislikers over here. Because these are the best presentations, even more than are delivered in our colleges 😊

Thank you for this video. It helped me out a bit.

thank you, your explanation is very clear. I want to ask permission to use this video to help my student understand the physiology of smooth muscle

Desmin and vimentin are found in all muscles, as they are part of the mesenchymal origin, that's the only correction I would make, other than that amazin. I like your videos!

you are great! greetings from an Israeli student

best lecture i have ever seen

Beautifully explained. So understandable and clear.

Thank you so much, it is so hard to find a video that explains well. Thank you

الله يعطيك العافية خوية

Thank you for this. Today is my test and man this helps alottt

So passionate. Much more informative than how my professor in General Physiology explains his lectures T--T Please be our professor lol. Thanks for this vid!

desmin and vimentin, in case anyone was wondering about the spelling

The best lecture I've listened to. Thank you for all the detailed information :)

You're the FATHER OF SCIENCE

Thank you very much for your great efforts

very good lecture you make it easier thak you

thank you so much...

Fantastic explanation. Keep up the good work man

So much police sirens in your videos, I heard them several times in different ones, what's rly happening there? :D

Hi. Why does a smooth muscle cell have only one nucleus?

Very helpful! You have beautiful handwriting!!

YOU ARE A LEGENDDDD!!!!

very nice

It is very good lecture , Thank you

Thankyou for the video, and how does relaxation occur?

Why is smooth muscle not striated?

hi, thanks for this wonderful explanation. so after i got the fundamental knowledge from here, i went to read further on the cytoplasm membrane and its compose of the caveoli, can u pls explain its function. thanks

awesome video!!

Amazing! ❤️

Thanks❤️❤️❤️❤️

Hi, I got a question. On smooth muscle cell thin filaments, do we find actine, tropomyosine and troponine? Does Calcium intervene in the same way than in skeletal and cardiac muscles? As there are no sarcomere structure, I was wondering about the other differences that can be seen. Thanks again.

thanks a ton! From Pakistan ✌

at 3:35 you can hear a siren

can the single units of smooth muscles can be ether controlled by the NS or can b under the non nervous control ?

AMAZINGGG VIDEOO!!!!!

"And what that means is..."

good though, thanks for the info!

thanks bro keep it up

Does the heart have smooth muscle ?

waww,,,,, Thank U so much... U're cooll dude ... I am agree with @chi an luu

8:16 screenshot for notes :)

U are my degree saver😭

Is that a siren?

i love you. Can i order an AK lectures tshirt to romania? :D thx

very fast

Can you really do this for a living with 27k views and staff? I mean I love your lectures, they are incredible, but how can you survive in this economy on KZfaq money?

💚💚🔥

can the single units of smooth muscles can be ether controlled by the NS or can b under the non nervous control ?