Steps of glycolysis | Cellular respiration | Biology

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Steps of glycolysis | Cellular respiration | Biology | Khan Academy

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Күн бұрын

Introduction to glycolysis. Role of glycolysis in producing ATPs and NADHs and converting glucose to pyruvates.
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Пікірлер: 417

@sccm100 7 жыл бұрын

Why do I feel like the more science you know, the more you realize the less you know.

@onetwoBias 7 жыл бұрын

It's a bit like if you inflate a balloon, the volume represents your knowledge, the surface area represents the things your discover that you don't know. I guess it's just that you first have to understand the basic concepts of something to realize how much there is to know about it and until you do, all of that doesn't exist to you.

@cosminbarbos4235 7 жыл бұрын

Kant has a theory about this. the more you know you are pushing your knowledge limitations further and you realize how little it represents.

@fizzakhalid3705 7 жыл бұрын

hahaha! same man!

@nikitakutakov1184 7 жыл бұрын

"As for me, all I know is that I know nothing" Socrates used to say. Humans are always the same:)

@TheCassholeJo 6 жыл бұрын

That means your learning and your way of thinking has been advised by several of my professors

@MrBones-bn7oo 6 жыл бұрын

‘mind wanders for 5 seconds’ welp time to go back 3 minutes

@deadmanperipherals 4 жыл бұрын

facts

@archstrider3509 4 жыл бұрын

That’s so true

@adelasefora 3 жыл бұрын

so true!

@gg025 3 жыл бұрын

story of my life

@luzmarinacruz7325 2 жыл бұрын

Seriously smh

@TurulHEMA 7 жыл бұрын

Cool. Now if I watch this 10 more times I might have it memorized. . . Maybe.

@onetwoBias 7 жыл бұрын

Write it down from memory instead - much more efficient

@lisab2631 4 жыл бұрын

Wow so fast?! (not even ironic)

@adelasefora 3 жыл бұрын

literally same

@TrapHut 3 жыл бұрын

@@onetwoBias I agree!

@mek2367 3 жыл бұрын

Maybe checkout a less detailed one? It's rly not tht complicated

@languageandmana9255 Жыл бұрын

Thank you for making FREE videos for PREMED students. Many intelligent students can't afford MCAT prep packages and even basic books! So you are doing a huge favor to them by making detailed videos on MCAT topics. All of the poor students are future doctors and they will be donating regularly to this amazing channel ❤ I wish a free medical school will be established one day just like Khan Academy, professional, kind and generous, in which people can study doctor of medicine for free.✨

@leeschloss4840 5 жыл бұрын

If my body was able to take my biology test for me, I would've totally aced it.

@earth6738 6 жыл бұрын

Kahn puts my $100 biology textbook to shame. He's straight up out here slaying the science game. Thanks, Kahn.

@mohamedmotaz5194 Жыл бұрын

Atleast spell his name right...

@gboy05 Жыл бұрын

@@mohamedmotaz5194 he clearly khant

@asmahaque8558 6 жыл бұрын

Stop sounding so excited, we hate glycolysis.

@ThingsUShouldLike 6 жыл бұрын

Lmao true

@fadeskywards1245 6 жыл бұрын

ahhahahahahaha This one takes the cake

@StreetDancer171 6 жыл бұрын

Nah, I enjoy learning about it, it's interesting to know what's going on in our bodies

@madhurajoshi3479 6 жыл бұрын

WaveDancer171 you do...And that's great! This is just the silly opinion of 90 percent of the people studying glycolysis..😑

@hashirrasheedhaider6508 6 жыл бұрын

WaveDancer171 you will hate it once you will see this in order to memorize it.

@aquariansage1451 7 жыл бұрын

Even if this man was speaking in Navajo, my current level of understanding would still be the same.

@caseylydon209 6 жыл бұрын

Aquarian Sage retweet

@anahiti2981 4 жыл бұрын

that is literally me 2 years later. funniest thing i read all day..

@Studley_Nilson 4 жыл бұрын

🤣🤣

@theobalatel34 3 жыл бұрын

you know it that well?

@eemiaa10 8 жыл бұрын

I have to memorize this for Tuesday. Lord help me.

@nicholasevans9490 7 жыл бұрын

May God help you.

@shkoata366 7 жыл бұрын

how did u do?

@eemiaa10 7 жыл бұрын

shko ata well I had Glycolysis down, but the rest of the exam was the beggining of my demise

@queenjazmyne 7 жыл бұрын

i need to learn al of this for this tuesday ha. Apparently tuesday is test day

@priscillacastro775 6 жыл бұрын

Aimee I have to memorize this for tomorrow...

@visneliturta0502 7 жыл бұрын

Great video, however one simple mistake: Kinases don't "dephosphorylate" molecules under physiological conditions. Enzymes for dephosphorylation reactions are called "phosphatases". The reason why the "pyruvate kinase" is called kinase is that while these metabolic reactions were being discovered, scientists tried out these reactions in vitro to see what the enzymes do and they put too much pyruvate and so turned the reaction balance in favour of phospoenolpyruvate (PEP) as product, so they thought, the enzyme phosphorylated pyruvate. But in reality, under physiological concentrations, the enzyme actually "dephosphorylates" PEP.

@kingofgames9154 2 жыл бұрын

Thank you for this nice information 👍 It can be crucial detail.

@linkh1435 4 жыл бұрын

I will always love biology the most. Chemistry, well, not so much. I mean it's quite an interesting subject but it makes me struggle so much at school. Same for Physics.

@jquizo8530 4 жыл бұрын

Weeeell, we have this topic for biology and I now only understand it more in Khan Academy than my Bio teacher.

@tomato-v8x Жыл бұрын

@@anshikasrivastava3951 Being indian has absolutely nothing to do with that

@madisonjoe1911 5 жыл бұрын

3:13 is aCtUaLLy litEraLly the epitome of expectation vs reality and I died

@marleyoo 4 жыл бұрын

best comment

@sumaiyazainab6986 3 жыл бұрын

i cant stop laughing !!!

@DJ.Harsh_Chopra 3 жыл бұрын

😭so tough for a class 10 student like me

@shay3242 7 жыл бұрын

I can's appreciate the complexity when I need to know all of this for a test lol

@Mugen_YG 4 жыл бұрын

I look away for 20 seconds and next thing you know, I'm as lost as a 3 year old in walmart by how much stuff you just put on the screen Sigh, that's biology for you

@NikNikNiken 9 жыл бұрын

Gosh this guys you'll be a voice actor; he's got such a soothing and calming voice ^_^

@madhurajoshi3479 6 жыл бұрын

Sloth no offence but to me he sounded really excited which was kind of annoying since I was breaking my brainpan to try make sense out of glycolysis....

@reemaalsweed6748 3 жыл бұрын

90% of the video: we talked about this in another video 10% of the video: actually explaining glycolysis

@shyamsharma530 2 жыл бұрын

Wish the number of your comment's likes add to your IQ

@apolloex00 6 жыл бұрын

Why is life so complicated!?

@mjeadeissa2980 5 жыл бұрын

Creativity of god

@Epopoi27 5 жыл бұрын

Yet another equation : law_of_physics x random x huge_amount_of_time x selection = complexity of life

@PhantomAyz 4 жыл бұрын

Cuz complexity makes life awesome

@thomasalberto613 3 жыл бұрын

the double meaning...👍

@shubhangnisharma6597 3 жыл бұрын

Coz we r science students✌

@ezioblazesit9017 4 жыл бұрын

This man knows everything, only rival to Johnny Sins himself.

@yassminmaher4997 5 жыл бұрын

i studied glycolysis for nearly 4 years and only that video makes me understand it

@lisagonzalez2902 4 жыл бұрын

Thanks SO much, for all the videos you provide... It's helped me a lot throughout my medical career in the Dominican Republic. I finished it, and will graduate soon. Right now, I'm studying for the USMLE and reviewing quite a bunch of knowledge gaps! I don't agree with the comments on how his speech is too excited or whatever. Precisely, that's what makes me NOT fall asleep or get bored, since the way he talks makes everything much more interesting.

@rosy5565 9 ай бұрын

You just made me understand the cycle in 12 mins that my teacher couldn’t in a 2 hours lecture. Thank you so much for putting this out for FREE

@maturename9817 5 жыл бұрын

hey, Mr. khan, Id really appreciate it if you could include printable versions of the notes that you write in the videos as a link in the video description.

@user-ui7xl9mz3w 4 жыл бұрын

me: finished the video Also me: and that's why i hate sugar.

@JunZDK 7 жыл бұрын

You really made it so much easier to understand. Thank you!

@davidadams255 4 жыл бұрын

MCAT is in one month. This is a life saver. Thank you!

@emeka3033 3 жыл бұрын

howd u do

@davidadams255 3 жыл бұрын

@@emeka3033 92 percentile! Thank you again!

@emeka3033 3 жыл бұрын

@@davidadams255 you legend, I’m studying for my first test in mid august

@davidadams255 3 жыл бұрын

@@emeka3033 best of luck my friend...make sure you work hard and make every moment of studying count. Perhaps even more important, make sure you give yourself time every week to rest and reward yourself for your hard work. Best of luck to you

@dina6177 5 жыл бұрын

“this over here was replaced with that over there”

@StreetDancer171 6 жыл бұрын

Dope video, I love how you actually enjoy what you're talking about and are enthusiastic about it!

@monaipsm 3 жыл бұрын

THIS IS THE BEST VIDEO ON GLYCOLYSIS EVER! Please do one like this on kreb cycle please!!!

@dannyawesome63 7 жыл бұрын

You just explained what my biochem professor has been trying to explain for the past 2 weeks. (and drastically failing at it) Thanks!!

@Autumnpaige19 6 жыл бұрын

DannyAwesome63 A professor had to explain this in bio chem?! Wow I am learning this in general biology. Makes me less afraid of biochemistry now!

@earth6738 6 жыл бұрын

I had to walk out of my biology lecture and just look this process up on Kahn Academy because there was no way I was going to absorb any information with the way she was teaching it.

@nicoletaylor1497 5 жыл бұрын

@@Autumnpaige19 Biochem, you learn the mechanisms and reproduce them.

@FavouredElm2 4 жыл бұрын

thanks to this academy, my grades aren't dropping like hell. love this channel

@gtarules1 7 жыл бұрын

It only took him 6 years to post the video. lol

@BereketMinisha Жыл бұрын

wow! BRILLIANT!,I am from Ethiopia East Africa and I love learning from your video!

@xdaebakxab6344 7 жыл бұрын

thank you so much for this vid! helped me so much! my biochem professor is clearly failing at explaining

@crystalkan4862 4 жыл бұрын

my teacher explained this in a way that is hard to understand, and i am soooo happy this channel exist

@Myleanne14 4 жыл бұрын

Great video, thanks for mentioning all the enzymes involved

@sirian3092 8 жыл бұрын

This video helps me a lot to understand the glycolysis process. Thanks!

@hillaryherrera2125 7 жыл бұрын

"3 cahhh bunn molecule" at 0:26 couldn't stop laughing at that part lol

@gabrielqin9687 3 жыл бұрын

Triosephosphate isomerase (TPI) is a perfect enzyme that catalyzes dihydrooxyacetone phosphate into 3-phosphoglyceric acid. There is an enol middle metabolite between these two steps. But this enol middle metabolite is easy to release phosphate group and become to malonaldehyde in a neutral cellular environment. The significance of TPI enzyme lies in that it has approximately 10 aa residues forming a loop that is designed to cover the enol middle metabolite preventing its release. In the end, as long as 3-phosphoglyceric acid is produced, this loop or cover will leave and let 3-phosphoglyceric acid go and do next reaction into 1,3- diphosphoglyceric acid.

@billcheney856 7 жыл бұрын

just for the record, the two kinase enzymes in steps 1 and 2 transfer a phosphoryl group, NOT a phosphate. It seems like splitting hairs, but it's important to account for the oxygen atom.

@lamimkader8823 7 жыл бұрын

itd be nice to have the whole page in one shot, so i could follow the reaction process

@gustavobasulto6759 8 жыл бұрын

In what Universe would anyone consider disliking this video. Thanks you 🙏🏻

@charlottedelaet5430 3 жыл бұрын

I always watch your videos if I need to study something or I need to teach it’s so well explained!

@tquathlouis2521 4 жыл бұрын

This is what I need for the exam next week 😌😌 Thanks God you are here Khan

@Leah-ep3wh 7 жыл бұрын

Had to memorize all the anabolic and catabolic processes for my upcoming test next week. Please bless my soul.

@memcore1312 Жыл бұрын

And I thought intro to microbiology was going to be easy 😂

@alyssaalcantara6739 6 жыл бұрын

I think it’s cruel that the A.P. Bio, 12u bio curriculum requires us to memorize the steps of glycolysis. Although, I do appreciate the complex process that allows us to break down sugar from food and convert into the universal energy currency, ATP.

@pouyaejtemaeimehr9352 6 жыл бұрын

Thank you so much. A wonderful review for SAT subject test for which I am preparing even though College Board requires me to know much less about Glycolysis than what this video taught me.

@ouiemfrs4373 4 жыл бұрын

I love you man come and teach in my University,:")

@linzhuo3099 8 жыл бұрын

Hi there, In the graph you drew, you only have 5 hydrogens for glyceraldehyde 3 phosphate. However, the formulate for this molecule is C3H7O6P. Just a little confused with why there are 2 missing hydrogen. Thank you so much

@farouk98kh 8 жыл бұрын

the phosphate is with or withour hydrogen atoms, since it reacts with water in an equilibrium reaction. He chose to draw it without the hydrogen; yet, we can still put the phosphate with the ti hydroxyles

@thepunlady3036 7 жыл бұрын

teacher moved test to tmrw. panicking. no time. bye

@Vic661 5 жыл бұрын

How’d it go

@Birthold 4 жыл бұрын

The people demand answers

@elissar2004 Жыл бұрын

The best! Thank you so much!!

@theblimo4747 5 жыл бұрын

Wow... I just began bio 20 and I’m already hooked on this, but I really should’ve taken Chem first!

@shyamraiyani6954 3 жыл бұрын

Superb explanation 👌👌👌🙏🙏🙏

@omarelhousseiny6155 2 жыл бұрын

Last 2 seconds of the video: "Actually makes sense" (JAW DROPS)👍

@blinbin8415 3 жыл бұрын

crying in the club rn my teacher didnt even teach us she gave us a ppt and some hw ffs

@michellegeorge1853 6 жыл бұрын

Amazing video. Very very helpful! Thank you Khan Academy!

@lili-cl1zx 3 жыл бұрын

great video, glad to know i can always come here for science help! :D

@tinashechidzambga5422 8 жыл бұрын

Thanks a bunch mate. That is exactly what I needed.

@arman8543 3 жыл бұрын

Thank you that was very helpful for me 🙏❤

@halaabdullah4168 7 жыл бұрын

Thank you very much you make my life easier !

@goshakrasovskiy7072 4 жыл бұрын

Can some one please explain where the second phosphate group that was attached on the glyceraldehyde came from

@FavouredElm2 4 жыл бұрын

just know that whenever there is formation of ch2oh in glycolysis, the h gets replaced by a phosphate group

@goshakrasovskiy7072 4 жыл бұрын

@@FavouredElm2 thank you so much I really appreciate it

@FavouredElm2 4 жыл бұрын

@@goshakrasovskiy7072 no problem

@gayathrymuthumani9946 4 жыл бұрын

Really helpful.. Thanks alot and much appreciated

@ferrariluther5910 8 жыл бұрын

majestirial,world class,sensational,brilliant,astonishing,intimate,definitive,point-wise.......

@iluvspongebob88 7 жыл бұрын

after the phosphoglycerate mutase step where does the hydrogen on the bottom of the next step come from?

@Itsme-rn1zb 3 жыл бұрын

Ur talking style and ur voice make me listen u again and again.. 😅😍

@alshorty85 6 жыл бұрын

Borrowing your brain to take the exams sounds better than this lol

@shaniw.4728 6 жыл бұрын

i thought i was the only one who thought like that

@madhurajoshi3479 6 жыл бұрын

Shani Williams I know right!!!

@normiel7135 3 жыл бұрын

Lol bet they graduated by now

@chezlise.holisticbeautyhea2012 6 жыл бұрын

This is GREAT!!! Thank you!

@juliam2070 Жыл бұрын

literally helped me SOOOOO******* MUCH thank you Khan!!!!!!!!!!!!!!!

@ghulammustafamemon3382 4 жыл бұрын

This is really appreciated. This one is the best one 😍

@xBlackShadowsZz 7 жыл бұрын

7:16 Whoa, a lil rant there you went there khan xD

@infiredpumpkins1970 3 жыл бұрын

Khan academy is a life saver

@khaleesi.1737 5 жыл бұрын

Have to freakin memorize this for report tomorrow. Wish me luck guys😭

@mickey9554 5 жыл бұрын

How was it? Gosh Amma report this next week help me

@foxy9403 2 жыл бұрын

you need to start putting adds on the videos my man.. they are so good.

@acmb364 2 жыл бұрын

To make it a bit more complex you could have drawn it in spiral instead of in circle. No, but seriously, thanks for the explanation! Very helpful.

@zabihafghan6409 7 жыл бұрын

Sir I want to learn the cell biology but my understanding power is normal but my memorizing Power is too low .what should I do to remember all the terminology

@ra1061 7 жыл бұрын

zabihullah ahmadzai Try some memory strengthening exercises

@zabihafghan6409 7 жыл бұрын

For example rayaad sir

@ra1061 7 жыл бұрын

zabihullah ahmadzai search and you will be hepled

@douglasw1545 6 жыл бұрын

Repetition

@helvinangolo2948 6 жыл бұрын

zabihullah ahmadzai .

@martinmitter5697 3 жыл бұрын

In my chemistry book and other sources there is one hydrogen less on the final pyruvate molecule. You have a full COOH group there, which one is correct ? Pyruvate with COO- or COOH ?

@JessicaMonterrubio 6 жыл бұрын

No matter how many times I watch this I still don't get it lol Lord be with me I have a test Wednesday

@jenetkolaparan7355 6 жыл бұрын

Hey girl! I found you here lol. No worries we are on the same boat.

@JessicaMonterrubio 6 жыл бұрын

Jenet Kolaparan lmao

@Nocturnal_Deity 5 жыл бұрын

I've taken chem 152, 200, and 201, and yet taking the intro bio class feels like i should've taken organic chemistry... why is organic chem not a pre req for bio 200....

@briemarie8609 6 жыл бұрын

This helped me so much, thank you.

@jbsilveradoo8788 4 жыл бұрын

You guys should run a few ads but only before and after the video. It is very profitable, and it would ensure your survival as a channel. Ads before and after the video also wouldn't interfere with the learning process in the same way that ads in the middle of the video would.

@mrsquidward9454 8 жыл бұрын

Omg thank you so much this really helped me for my freshman bio class

@maheentahseen9039 4 жыл бұрын

Lmao your voice literally made me excited when reaching the end😂 anyways, I always understand anything through your videos. Love em❤️

@needarandomname4330 7 жыл бұрын

Thanks. My text book had a description that didn't match it's diagrams. Why can't there be at least one text book in this world without errors?

@hrushikeshjani8722 5 жыл бұрын

How can we appreciate its complexity

@darrenrodrigues4486 7 жыл бұрын

2 atp for anaerobic and 38atp for aerobic respiration energetics.

@stephenstralka6391 5 жыл бұрын

I real appreciate this video. Helps too much

@marielabandero846 4 жыл бұрын

Its our exam day and im watching , cramming is life

@eden5695 2 жыл бұрын

thank you for the vidya, you got a fire voice

@wazatojanaiyo 7 жыл бұрын

I often hear Sal or other presenters make reference to other videos that they've already made that cover topics that come up in this video. Since I occasionally am just happening to come across thee vids while browsing KZfaq, it would be helpful if they could provide links to the videos they're referencing. I'd after all like to watch those too, and it would save me some time from searching through Khan Academy's library. Just an idea.

@robinporter8725 6 жыл бұрын

FYI your arrow in step two is a resonance arrow, not a reaction equilibrium arrow!

@SirreTV 8 жыл бұрын

Nice video! Actually the enzyme hexokinase is accompanied by the enzyme glukokinase which works at higher glucose concentrations. Otherwise, pretty cool!

@Nidacolada Жыл бұрын

Haha, gotta love the excitement :D Thank you

@donmaanao7279 5 жыл бұрын

The magnesium coupled atp is to make sure as you break atp to adp you dont go throwing energy grenades all around the cell. So the magnesium is used to stabilize the phosphate offloading.

@donmaanao7279 5 жыл бұрын

Hexokinase is also deliberately used to trap the glucose in the cell. To create a negative charge on glucose and allow for repulsion to the cell membrane.

@georgemutale5298 5 жыл бұрын

i find everything about this so simple

@roxanazelaya2113 4 жыл бұрын

We are so ungrateful sometimes for the opportunity we have to learn this in school. I still don't get it though.

@shummu1458 4 жыл бұрын

Now glycolysis sat in my mind😍

@khushidogra4677 7 жыл бұрын

Thnxs this is very helpful of my study

@maybenikhil 7 жыл бұрын

I learned this at the start of my school year. Forgot it by the end

@ashleyplease7479 6 жыл бұрын

Hi there, during the cleavage phase, what molecule or enzyme splits the p-c3-p into the G-3-p?

@satellitesage2487 7 жыл бұрын

Step 6 of glycolysis is converting glyceraldehyde 3 phosphate to 1, 3-bisphosphoglycerate which has a chemical formula of C3H7O6P and C3H8O10 respectively. G3P gives one of its hydrogen to NAD+. I don't understand where did 1, 3-bisphosphoglycerate get its 2 hydrogen and 4 oxygen.