#mRNAVACCINE #mRNA #Moderna #Pfizer #Weniverse
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As interest in mRNA vaccines increases, interest in Modena and Pfizer companies is also increasing. The mRNA vaccine that came out in the world through Covid 19 has a lot of impressive stories. They had to overcome a lot of difficulties.
In this video, I will talk about the more fundamental technical difficulties of the mRNA vaccine and what efforts the scientists such as Katalin Karkco and Drew Weissman had to solve it. In the story, you will naturally find out mRNA codon, UTR, poly A tail, cap, methylation, lipid nanoparticles, etc. Let's also look into the history of Moderna and Pfizer BioNTech and find out some people like Stephen Bancel and Ugur Sahin.
Lastly, I will talk about the meaning of the success of the Covid19 vaccine in Moderna and Pfizer BioNTECH.
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00:55 Discovery of mRNA
01:39 mRNA Technology Difficulties, Immunity Response
3:15 Kataline Kariko and Drew Weissman | Methylation and modRNA
3:52 The Birth of Moderna and BioNTech | Derrick Rossi and Ugur Sahin
5:09 How mRNA works | Codon
5:52 Codon Optimization
6:59 UTR, CAP, Poly A Tail Optimization
7:40 Lipid nanoparticles and macrophages
8:28 mRNA Vaccine and Technology Potential | mRNA OS
9:30 mRNA Technology of South Korea and the United States
10:00 Weniverse Membership
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Reference
Katalin Kariko Photo by Wikipedia, Krdobyns derivative work: Innisfree987
Drew Weissman Photo by Wikipedia Nicholas D'Amico, Gallantry Media Group, LLC
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