For people looking for yield percentage, it is 89.15 %

she put 6 drops fml she failed the lab

thanks to quarantine this is how i "learn" now

She sounds like Jodi Foster in “Silence of the Lambs” and “Hannibal”

This is a very well equipped lab!

That was very very helpful! I have this lab tomorrow. I wish i can keep the percent yield higher than 80%. My chem teacher said it is very hard to do so.

Thank you so much for posting this lab. My organic chemistry lab at Sierra College made this and it was one of the best education lessons I've ever received. Jackie RDH

this has been so helpful, thank you

I swear when I messed up this lab in college, that was the first sign to me that "Oh, I'm not cut out for this." I don't know where I messed up, I probably left it on the heat too long, but by the time the crystals should have started formed and we're supposed to collect it using the sidearm flask and suction filter, it was a _paste._ I swear I did all the drops, all the steps, all the temp and timing and waiting. But I obviously MUST have messed up. *It was the easiest lab,* but for some reason physics just _breaks_ whenever I do any sort of chem lab, so no matter how studious, by-the-book, perfectionist I am, my results MUST be human error. Even in high school, when we were recording what melted faster, crushed ice vs cubed ice, MY CUBED ICE MELTED FASTER! THAT'S NOT POSSIBLE! but I SWEAR I didn't mess up the recording even though _I must have._ I love cooking and baking so I'd thought I'd be good in chemistry or even pre-med but HO BOY NOPE.

take a shot every time she says aspirin

Thx. Observation is a way better learning tool that reading.

Aspirin = boil benzene C6H6 + add acid acetic ( vinegar) CH3COOH +catalyser KOH until evaporated Leaving crystalline white sour powder residues which are aspirine that I had made 45 yrs ago During my pharmacy student in Cambodia

This helps a lot! Thank you for demonstrating!

thank you, you helped me alot ♥

Thanks! This helped me a lot for my science project.

Aspirin and Sprite is my favourite synthesis ✨

Above 80 °C salicylic acid esterifies the OH of a molecule with the COOH of another molecule of the same species forming a dimer and not acetylation, and this product precipitates with the acetylated species. In order to avoid this parasite reaction you should operate in hot waterbath but below 80 °C. Then basifying the crude acetylated product till solution, you can filtrate it from eventual dimer esther, then acidifying the solution you recover only the acetylated product that you can recrystallize. You can check for unreacted salicylic dissolving a drop of reaction mixture in a test tube with a Fe3+ solution, if it turn deep blue, there is unreacted salicylic.

Great!

can someone please tell me how i can get the information for the chemicals and apparatus used in this video?

Thank you for this information

This helps a lot

The liquid you have in the erlenmeyer after the last filtering is cloudy. Is that not lost aspirin? It seems you had more after the first filtering.

thanks for sharing

she added 6 drops of sulfuric acid...

awesome vid that will be my lab exam on monday

Qué buena explicación, un saludo

i will use this for my students thanks

Thank you so much

what is the concentration of the salicylic acid, acetic anhydride, H2SO4 and ethanol used?

whats the thoretical yield

Why no gloves though? Is this a situation like fuming nitric acid where no gloves is better than gloves? And a fume hood? Acetic anhydride is pretty toxic to my understanding. LC50 is 1000ppm/4H according to Fischer MSDS.

Is that tap warm water? So 40 to 50 degrees?

Hi could you perform the 2,5 Di hydroxy 1,4 diathine synthesis? I will provide the complete details

she makes it look easy.

The moles doesn't matter. It's used as a solvent. Sure it's good for very very precise experimentation, but it really doesn't matter in the end

Yay science!

what temperature was your hot plate?

it good but what i want to ask you is if there is no solution of acetic anhydride form the soild acetic anhyidide parezent how we can change to solution ? and also in which solvent we can prepare in water or hexane or what i want to ask you is we can prepare in polar or in non polar we can prepare the solution ? than you

H2so4 or h3po4 which Is best to use in this rxn

is acetic acid one of the products? what is the chemical equation for this experiment??

That was six drops lady

еее, клёво, спасибо!

Great video! Where can I find an explanation of the theory of this synthesis?

Hello PLM classmates

i need stuff like manufacturers info, model,etc

Why does it look so safe when she does it, doesn't even smoke, she pour everything at once

It's dolly parton!

very informative..thanxx for adding this... i hv a question...can v replace acetic anhydride with acetyl chloride???

Acetic anhydraide is banned here. Is there any alternative

I need to take 30 mg of aspirin daily, but there is no such thing as 30 mg aspirin tablet. So, I am thinking about putting ten 81 mg aspirin tablets in a bottle, adding 27 units of water, then shake it well and take one unit of the compound daily, would that work? I see some solid looking thing at the bottom of the bottle and am wondering whether that is the only aspirin because if that's the case, it's impossible to take 1/27th each time. Not even close.

Just interessiert Does anyone know the chemical equation for this reaktion?

how much acetic anhydride did she use?

can someone tell me the concentration of the acetic anhyderide????

Can you tell me the quantity of ethanol you are using?

Than you

Where's your gloves young lady!!

how many ml of ethanol was used?

hello, clarice

whats the benifit of this acid

i just learned , alcohol + aspirine working very fine

Very informational video. I would be very grateful if I could get a link to webpage where I can find the theory and complete information in documented for.:)

👌🏾

It doesn't matter. If the hot plate was 200 Centigrade the boiling water would be 100 Centigrade. If the hot plate was 500 Centrigrade, the water would still be 100 Centrigrade.

How aspirin is absorbed by the body as a treatment when it is not dissolved with water🥺

❤❤

Sir how to make anti iron . What is the chemical name.. Pls.

Hello! How much ethanol is needed to dissolve the crystals?

gloves???

what was your percent yield?

1_قم بوضع 3 جرامات من حمض الساليسيليك، ثم قم بوضعه في دورق أضف 6 مل من أنهيدريد الخل. 2_أضف من 5 إلى 6 قطرات من حمض الفوسفوريك إلى القارورة.قلب هذا الخليط جيدا، عن طريق رج القاروره. 3_ثم ضع هذه القارورة في دورق من الماء الدافئ لمدة 15 دقيقة. 4_أضف 20 قطرة من الماء البارد إلى الخليط الدافئ، وذلك حتى يتكسر روابط الأنهيدريد. أضف 20 مل من الماء إلى القارورة. 5_ضع هذه القارورة في حمام جليدي حتى تتم عملية البلورة. 6_عند ملاحظة بدء عملية البلورة، قم بصب الخليط عن طريق قمع Buknar. 7_قم بعملية الترشيح من خلال الشفرة، ثم قم بغسل البلورات المتكونة عن طريق وضع ملليمترات من الماء المثلج. قم بنقل تلك البلورات إلى دورق آخر. 8_أضف 10 مل من الإيثانول إلى الدورق ثم قم بالتقليب و التحريك حتى تذوب تلك البلورات. 9_أضف 25 مل من الماء الدافئ إلى محلول الكحول. تغطية الدورق. سيتم إصلاح البلورات عندما يبرد المحلول. تأكد من وجود حمض أسيتيل الساليسيليك عن طريق تحقيق من درجه الانصهار عند130درجه سليزيه

I'm just here to learn how to make medicines cuz of the supply shortage coming. Y'all call me crazy, and I hope I am. But 2021 is gonna be rough, and I'm gonna be prepared

Bruhhhhh where does one get so much acetic anhydride XD

Instructions unclear, I ended up creating Sky Blue crystal meth

in our class we used H3PO4, would there be any differences between the two in the final product formation?

Meryl Streep Makes Asprin

لماذا أضفنا الماء المثلج

What was the theoretical yeild?

gloves?

Where's the gloves ?!

Breaking bad 🤘🏻

Can u upload some what pilot plant method or set up?

If you get a migraine, you should try smoking some of those crystals

why you add cold water in the aspirin?

Would it be safe to ingest homemade aspirin?

Where are your gloves?

now I have to learn marketing and sales

She added six drops ;]

Great video but please no watches in a lab!

How do we get salicylic acid and how do we know that salicylic acid is really salicylic acid

Would this aspirin be safe for human consumption??

How the hell did she get her hands on AAA?

This old experiment

Wait a minute, those Are literally common pickling acids.

Seems counterintuitive to make aspirin with salicylic acid since the body turns aspirin into salicylic acid which is what nums pain.

طلاب كلية النور شونكم يابة مبين ما شاء دا تفهمون 😂😂😂

Help me

this dude really out here with no gloves smh

what's with the Neanderthal aspirator??????

why do you weight the filter paper ?

That's the reason why to study ⚗. Chemistry. In future you can create your own drugs..