Orian Leitersdorf presents us with the contributions he’s made to a lab at the Hebrew University working on Organ-on-Chip technology. His talk truly embodies our TEDx’s theme of the power of youth. Orian Leitersdorf, senior at WBAIS attending the Technion next year, possess a passion for learning and problem solving that drives him to explore subjects beyond his focus of Computer Science. For the past year, Orian has been actively participating in the Organ-on-Chip project at the Bioengineering Nahmias Laboratory from the Hebrew University. The Organ-on-Chip technology aims to meet the demand of the pharmaceutical industry for the preclinical phase of development by incorporating advanced tissues cultures in order to develop environments which can better mimic the physiology of humans. The specific Organ-on-Chip variation developed at this laboratory involves spheroids with embedded oxygen sensors as measurements of metabolic stress, providing crucial information beyond live-dead analysis. Combined with Orian’s contributions through software analysis platforms, the project hopes to significantly impact drug discovery and personalized medicine going forward. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx