Michael Lidsky, MD, Associate Professor of Surgery at Duke Health, and Cathy Eng, MD, FACP, FASCO, David H. Johnson Endowed Chair of Surgical and Medical Oncology at Vanderbilt-Ingram Cancer Center, discus the PUMP trial - an open phase 3 comparison of hepatic arterial infusion in addition to standard-of-care chemotherapy versus standard-of-care chemotherapy alone in treating patients with colorectal cancer and unresectable liver metastases.