Be nice to yourself, and never feel lonely. Cuz billions and billions of your cells are fighting for you and protecting you with their lives.

As a neutrophil, this was very accurate, good job. 👏

Terrific way of depicting complex systems visually, and much easier to understand than in books.

The immune system has never been so epic. Very interesting and nice animation.

What an amazing video! High quality and clearly explained without being too quick!

Oh man I didn't want it to end. That was a good video please do a part 2 thank you.

Extremely amazing!!! Wonderful animation and spectacular music and clear narration! Thank you!

Full video in comment In this animation, we want to show the human immune system with images never seen before. We will learn how macrophages, as well as other cells and mechanisms, protect our organism from death every day. Our skin, like the bark of a tree, represents valuable protection. However, the skin is also home to countless microorganisms, among other things, nourished and protected by an oily fluid called sebum, which is produced by sebaceous glands. Sebum contains antimicrobial elements that can kill harmful microbes or too many microbes on the skin, creating a harmonious coexistence between skin cells and microbes, a kind of symbiosis. Microbes also keep one another in balance and kill pathogens dangerous to our cells. The protective layer of hollow organs such as the nose, mouth, and trachea is a mucous membrane. Mucous membranes possess cilia that move mucus, to which foreign substances adhere, upward into the oral cavity. If mucociliary clearance is not sufficient, an attempt is made to achieve clearance of unwanted particles through coughing. This is done by inhalation followed by a sudden exhalation to remove foreign substances from the lungs and trachea. The bone marrow has stem cells and is the birthplace for many different immune cells, which are also called leukocytes. Stem cells divide to form daughter cells, either asymmetric or symmetric. Symmetric cell division results in either two stem cells or two progenitor cells. The progenitor cells divide again and again, so a single stem cell becomes many immune cells or leukocytes. One common immune cell is the neutrophil, and some remain in the bone marrow, while others enter the bloodstream. Our neutrophil belongs to the so-called innate immune system and moves through the blood vessels during inflammatory processes. The endothelial cells of the blood vessels have special receptors, leading to a process called diaeresis. Neutrophils follow cytokines, signal substances of other cells, in the connective tissue. Neutrophils' job is to eat bacteria through a process called phagocytosis, and they also produce certain cytokines that attract other granulocytes and cells of the innate immune system, like macrophages. Macrophages arrive on the scene before neutrophils phagocyte bacteria and produce signal substances like tumor necrosis factor, which suppresses hunger, causes fever, and stimulates leukocyte production. Another type of leukocyte is the T cell, which possesses receptors to recognize antigens presented by antigen-presenting cells like macrophages. T cells are formed in the bone marrow and mature in the thymus, where they develop antigen receptors. Some migrate to secondary lymphoid organs like lymph nodes and the spleen. Naive T cells meet dendritic cells in secondary lymphoid organs, which have already had contact with a pathogen and present antigens on their surface. T cells scan dendritic cells for antigens, and if a match is found, activation and clonal expansion occur. Cytotoxic T cells, a type of T cell, scan other cells for antigens. If they find the antigen, they induce apoptosis in the infected cell, eventually eaten by macrophages. In addition to cytotoxic T cells, there are T helper cells, memory T cells, regulatory T cells, and others. T helper cells work with B cells, which originate in the bone marrow, and search for specific antigens. B cells can activate immediately or present antigens to T helper cells, leading to clonal expansion and the production of plasma cells, memory B cells, and antibodies. Antibodies produced by plasma cells bind to antigens, rendering toxins harmless and marking antigens for phagocytosis by macrophages. This process is called opsonization. All immune cells originate from stem cells, which develop into progenitor cells and eventually immune cells. Other important immune cells include natural killer cells and platelets. Platelets, also known as thrombocytes, originate from megakaryocytes in the bone marrow and are essential for blood clotting. If an injury to a blood vessel occurs, platelets adhere to collagen fibers and each other, forming a platelet plug, followed by the formation of fibrin strands that bind more platelets and red blood cells, resulting in a strong clot.

Thank you guys for the excellent job! I'm so impressed and glad to see how this immune system works with my own eyes actually. It's hugely helpful.

The information is presented as if it's an Intel briefing before a mission. It has me on the edge of my seat. 😂

x-cell-ant.

What an outstanding presentation! Thank you sincerely for posting this video. It is excellent in refreshing my knowledge in Human Immune System Biomedicine, and I'm stoked with it.

Beautiful! Also simple enough to show and learn my kids about this! Thank you!

Just keep making these type of videos 😭❤️🙏 so that we could be eternal grateful to u for that !!

Thank you very much Dear Dr. Thomas for this amazing presentation on the subject so precisely, and I have not seen a video tutorial to this depth of detail in the subject of human immune system. God Bless You..... 💐💐🙏🙏

Watching this for my immune system military can get motivation, battle strategies, and train recruit immune system soldiers

I was so deeply stucked in that animation that it became very difficult to come out of it . appreciable work .❤❤❤ Love from India 🙏🙏✌️✌️

I love being covered in sebuma and half exploded micro organisms! So comforting to know! Thanks

Very informative. Thank you! Beautiful animation too.

A beautiful journey understanding the mechanism of human immune system...thanks for the effort ❤️

Thank you for the qualitative videos

Beautiful! Thanks for this masterpiece 😄

Incredible animation! Thank you!

Wow that’s amazing, a real eye-opener! Thank you!

Great animation. I’m sure many would appreciate this.

Everything is perfect... The explanation is really impressive, the animation is meticulously done. Thank you 👍

The micro human body is so amazing!

What an incredible animation and explanation! I love it

Great video! Thank you so much!

Fantastic to get deep knowledge of immune systems and producing cells. Thanks from a pharma student.

🎉 thank you for this peace of information Dr.

Gratitude to You for your great effort!

Thank you so much for the animation!! I am self-learning immunology and this definitely helped me visualized and imagine how different leukocytes operate :)

Thank you for the beautiful and informative video🙏

Magic work amazing every thing in the video is perfectly prepared, Thank you very much

As a medical student, I think that this video is one of the most amazing I have ever seen.

Whaouh, beautiful and well made animation ! Thanks for sharing

This is an amazing video!!!! Especially for the visual learners

Sir Thom you're a genius. The best teacher. Many thanks...Keep going.....

Good job brother! I am speechless!

Thankyou for this video. Very interesting about the immune system.

Wow.. Super.. Enjoyed very well the immune system journey. 👏👏👏

Excellent production!

Thank You For Your Precise Pristine Explanation.... I Love This 💗💗💗🍏🍏🍏🥑🥑🥑

Plz keep making these types of medical videos ❤❤❤

Had fun watching this, felt like some action thriller while being very informative

THIS IS THE BEST VIDEO I'VE EVER COME ACROSS ON IMMUNE SYSTEM!!!

this is the best explanation on immune system i have watched so far. thank you for creating this masterpiece! it feels like i'm watching an action movie, and at the same time learning about my body

Excelente, muchas gracias

Wow!!!! great work it reminded me the whole hematology 😊

Amazing creations of the nature

Best animated video and very helpful and easily understood..👍 unbelievable movements

My exams next week and it's helping me to understand everything

Mind blowing presentation!!!!

Thanks very much 🥰

Inside human body looks like another world 😮

What an outstanding presentation and animation. I am studying for a nursing major, and I am visual learning; your channel helps me learn and memorize. Thank you so much

Very interesting and nice animation❤

Beautiful video!

thank you so much❤❤❤ now i can say that I understood the science lesson

I just want to say....WOW 🙌👌

Immensive immune cell representation

Thanks for making these videos 👍👍👍

It’s the power of our one only god that allows to those cells to work with this regularity and specific methods.. am speechless ALHAMDOULILLAH 🤲🏻❤️

I just can't get enough of the immune system. Wish this was taught in schools

Excellent work on the animations. Like and watched

That was really a great expalanaition with animations keep going😊

Such a great video to help learn more in depth about the immune systemin the human body thank you for sharing.

Wonderful presentation

you are the best thank you

Thanks a alot for amazing video😊😊😊

Best video hands down ….

thank you so much i AM SO MUCH GRATEFUL

Always amazing 😍 videos

Superb indeed!

Thank you

How amazing and beautiful is our immune system. ❤❤❤❤

Excellent and thank you

Thanks a lot brother.. this is very helpful for me for my exams

Awesome!!!!!!

Thanks a lot

This music is SO intense lol I feel like a super hero learning about my body getting ready for battle

Amazing piece of knowledge, right❤

incredible

Thanks i love the video u had work hard bro ❤

How did the camera survive in the body😂 Excellent explanation ❤

This is the best!!!!!!!!!❤❤❤

You deserve billion of subscriber please upload more videos about biology

Impressed

The immun systeme fonction is fantastic 😊

Amazing

subhanAllah ❤

i wish i could kiss my immune cells and say thank you for protecting my potato existence 😂🙏

Amazing 👏

Really it’s very very good thank you deeply

Amazing 🤩🤩 many thanks greetings from Egypt 🙏💖😚

Tnx alot

Amazing!!

Please make an animation about how heart and kidney work. Your video about digestive system helped me a lot.

Awesome 😊