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Ethylene glycol is the most common ingredient in automotive antifreeze. But for years it was used in homicidal poisonings. What made this household chemical so dangerous? And why is it no longer a viable poison?
#chemistry #poison #antifreeze
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Credits:
Executive Producer:
Matthew Radcliff
Producers:
Elaine Seward
Andrew Sobey
Darren Weaver
Host:
Alex Dainis
Scientific Consultants:
William Porter, Ph.D.
Michelle Boucher, Ph.D.
Leila Duman, Ph.D.
Executive in Charge for PBS: Maribel Lopez
Director of Programming for PBS: Gabrielle Ewing
Assistant Director of Programming for PBS: John Campbell
Reactions is a production of the American Chemical Society.
© 2022 American Chemical Society. All rights reserved.
Sources:
Intentional Ethylene Glycol Poisoning Increase after Media Coverage of Antifreeze Murders
www.ncbi.nlm.nih.gov/pmc/arti...
Woman pleads guilty to killing husband with antifreeze
www.delawareonline.com/story/...
Homicidal Ethylene Glycol Intoxication
journals.lww.com/amjforensicm...
Ethylene glycol poisoning: Quintessential clinical toxicology; analytical conundrum
www.sciencedirect.com/science...
Ethylene Glycol Toxicity
www.ncbi.nlm.nih.gov/books/NB...
Alcohol Dehydrogenases
www.sciencedirect.com/topics/...
Why Is Antifreeze So Delicious?
slate.com/news-and-politics/2...
Bitter and sweet components of ethanol taste in humans
pubmed.ncbi.nlm.nih.gov/10940...
Alcohol Metabolism: An Update
pubs.niaaa.nih.gov/publicatio...
Biochemistry, Lactate Dehydrogenase
www.ncbi.nlm.nih.gov/books/NB...
Signal transduction and information processing in mammalian taste buds
www.ncbi.nlm.nih.gov/pmc/arti...
What Are the Toxicological Effects of Ethylene Glycol Poisoning?
www.atsdr.cdc.gov/csem/ethyle...
Antifreeze and Engine Coolant Being Bittered Nationwide
web.archive.org/web/201212282...
The impact of bittering agents on pediatric ingestions of antifreeze
pubmed.ncbi.nlm.nih.gov/19571...
The impact of bittering agents on suicidal ingestions of antifreeze
pubmed.ncbi.nlm.nih.gov/18584...
Toxicology of E-Cigarette Constituents
www.ncbi.nlm.nih.gov/books/NB...
Food additive could serve as a safer, more environmentally friendly antifreeze
www.eurekalert.org/news-relea...