Toxic by Britney Spears is featured in 100, the twelfth episode of Season Five. It is sung by Quinn, Brittany, and Santana. They re-did the song previously sung in Britney/Brittany, the second episode of Season Two, as part of the show's special hundredth episode.
Brittany is in the process of telling Santana what her life at MIT is like. She tells her ex-girlfriend how they keep her occupied with answering difficult calculations most of the time, and that she has next to no free-time. To make Brittany enjoy herself, Santana suggests they reunite their friendship with Quinn. The threesome thus sings Toxic together. They start out dancing in the cheerleading uniforms they wore in high school. This is shown intercut with them dancing in the auditorium on an elaborate set wearing exotic costumes.
Quinn's new boyfriend Biff barely pays attention to the performance, foreshadowing his nature.
LYRICS:
Brittany, Quinn, and Santana:
Ah, ah, ah ah ah ah
Ah, ah, ah ah ah ah
Quinn:
Baby, can't you see
I'm calling
A guy like you
Should wear a warning
It's dangerous
I'm fallin'
Brittany:
There's no escape
I can't wait
I need a hit
Baby, give me it
You're dangerous
I'm lovin' it
Quinn with Brittany and Santana:
Too high
Can't come down
Losing my head
Spinning 'round and 'round
Do you feel me now
Santana with Brittany and Quinn:
With a taste of your lips
I'm on a ride
You're toxic I'm slipping (Santana and Brittany: under)
(Quinn: With a taste) of a poison paradise
Brittany with Quinn and Santana:
I'm addicted to you
Don't you know that you're toxic
And I love what you do
Don't you know that you're toxic
Ah ah ah ah
Santana:
It's getting late
To give you up
I took a sip
From my devil's cup
Slowly
It's taking over me
Quinn and Brittany with Santana:
Too high
Can't come down
It's in the air
And it's all around
Can you feel me now
Santana with Brittany and Quinn:
With a taste of your lips
I'm on a ride
You're toxic I'm slipping (Brittany and Santana: under)
(Quinn: With a taste) of a poison paradise
Brittany with Quinn and Santana:
I'm addicted to you
Don't you know that you're toxic
And I love what you do
Don't you know that you're toxic
Brittany:
Don't you know that you're toxic (Quinn and Santana: Ah ah ah ah)
Brittany, Quinn and Santana:
Oh, o-oh, ah ah ah
Oh, o-oh, ah ah ah
Quinn with Brittany (and Santana):
With a taste of your lips
(I'm on a ride)
(You're toxic I'm slipping) (Brittany and Santana: under)
(Quinn: With a taste) of a poison paradise (Santana: Oohh)
I'm addicted to (you)
Don't you (know that you're toxic)
With a taste of your lips
I'm on a (ride)
You're toxic (Quinn and Santana: I'm slipping) (Santana: under) (Brittany: Toxic)
(Quinn: With a taste) of a poison paradise
Brittany with Quinn (and Santana):
(I'm addicted to you)
Don't you (know that you're toxic)
Brittany with Quinn (Santana):
Intoxicate me now (Ooh)
With your lovin' now (Ooh)
I think I'm ready now
Quinn (Santana):
I think I'm ready now (Ooh)
Brittany with Quinn (Santana):
Intoxicate me now (Ooh)
With your lovin' now (Ooh)
I think I'm ready now
Brittany, Quinn, and Santana:
Ah ah ah ah