Tumor Markers: AFP, CA 125, CEA, hCG, PSA - clin chem review

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Dr. A's Clinical Lab Videos

Dr. A's Clinical Lab Videos

3 жыл бұрын

A clinical chemistry review video on the most common tumor markers, incluing AFP, CA-125, CEA, hCG and PSA. Based on information from the Larson and Bishop clinical chemistry textbooks.
PDF of slides drive.google.com/file/d/1FGd2...
The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

Пікірлер: 20
@chloepeterson1854
@chloepeterson1854 2 жыл бұрын
I keep getting positive pregnancy test while not pregnant. I’m going to for lab work on Wednesday. This is one of the only places I’ve found another reason for HGC could be present. Thank you 💕
@uazhar2013
@uazhar2013 3 жыл бұрын
Wow you explain it better than my professors!
@malikmakki9550
@malikmakki9550 2 жыл бұрын
Thank you for the valuable information. Could please clarify why CEA can be elevated in healthy individuals?
@DrAsClinicalLabVideos
@DrAsClinicalLabVideos 2 жыл бұрын
Hi. The short answer is that we know it can be elevated in non-cancerous conditions but we are not sure why. Since it is a protein produced in the embryo as it grows in the womb, once we are adults we should not have any in the blood stream. I personally wonder if it is due to conditions that cause a high cell turnover.
@gazmendggg5733
@gazmendggg5733 Жыл бұрын
My mother's CA125 increased after 6 months after receiving chemotherapy, from 10 to 180 uml, now after receiving 3 chemotherapy the value of CA125 is 28, is this good?
@DrAsClinicalLabVideos
@DrAsClinicalLabVideos Жыл бұрын
Tumor markers are used as part of the monitoring process. When the levels go up from a previous reading, it usually means the tumor or cancer is back or growing, when the levels go down, it means that the treatment or therapy is working. This is considering the patient’s whole picture of what is going on with them.
@cali_smartb5098
@cali_smartb5098 2 жыл бұрын
What do the numbers indicate even if the number is in normal range it’s confusing my Alpha fetoprotein tumor marker was 3.8 what does the number indicate?
@DrAsClinicalLabVideos
@DrAsClinicalLabVideos 2 жыл бұрын
The number is a concentration of this type of protein in your blood. If it is in the normal range, then it simply means that you have as much AFP in your blood as the average person. AFP as a cancer marker is useful in the context of monitoring cancer, treatment success, recurrences, etc. If it was present and elevated at diagnosis. AFP is also used to monitor fetal health during pregnancy as it can help detect neural tube defects and genetic conditions such as Down syndrome
@cali_smartb5098
@cali_smartb5098 2 жыл бұрын
@@DrAsClinicalLabVideos thank you for the reply I was nervous because means was higher than my cousin by 1.2 and it made me wonder like why the numbers anyways and why would one’s number be higher but still classified as normal. I was telling myself I need to watch it because 3.8 is normal but my cousin’s was 2.6 I really don’t like the normal range number chart at all.
@DrAsClinicalLabVideos
@DrAsClinicalLabVideos 2 жыл бұрын
Cali, the normal ranges attempt to capture what your average healthy person would be. But we are all different and unique, which is why it ends up being a range based on healthy population data and one person's normal can be slightly different than another person's normal.
@cali_smartb5098
@cali_smartb5098 2 жыл бұрын
@@DrAsClinicalLabVideos meaning I could be not as healthy as he next person. Can the numbers decrease and if so what can help that?
@DrAsClinicalLabVideos
@DrAsClinicalLabVideos 2 жыл бұрын
not sure that you could characterize it as "not as healthy as" but more like "not the same as". we are still unsure of the function of AFP in healthy humans, but it is useful as a tumor marker in liver cancers. So if you wanted to focus any health promoting efforts, why not focus on a healthy liver? we can all do well to have a healthy liver!
@mohammadamirulmusa4446
@mohammadamirulmusa4446 2 жыл бұрын
my CEA reading is 6.84....is it still normal?
@DrAsClinicalLabVideos
@DrAsClinicalLabVideos 2 жыл бұрын
Look at your report for the normal range for their machine/methodology. They are not standard
@mohammadamirulmusa4446
@mohammadamirulmusa4446 2 жыл бұрын
@@DrAsClinicalLabVideos what does it mean dr?😅 I'm not understand
@DrAsClinicalLabVideos
@DrAsClinicalLabVideos 2 жыл бұрын
it should indicate on the report if this is within the normal range (also known as the reference range)
@mohammadamirulmusa4446
@mohammadamirulmusa4446 2 жыл бұрын
@@DrAsClinicalLabVideos normal range 0-5...
@DrAsClinicalLabVideos
@DrAsClinicalLabVideos Жыл бұрын
Here is some more info about the CEA test. It is most helpful if you follow up with your doctor and get it checked again by the same lab to see if it changes. www.testing.com/tests/carcinoembryonic-antigen-cea/
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