Uric Acid - The Acid You May Need to Drop - with Dr. Johnson

No video

Uric Acid - The Acid You May Need to Drop - with Dr. Johnson | The Empowering Neurologist EP. 138

Рет қаралды 309,857

2 жыл бұрын

Fructose and Uric Acid - What Once Helped Us Survive Now Poses an Existential Threat
The interest in uric acid, well beyond its role in gout, focusing on its pivotal role in metabolic issues, is expanding rapidly, and globally. Without question, one important reason for this new understanding is the work of Dr. Richard Johnson, professor of medicine at the University of Colorado School of Medicine.
Dr. Johnson has an exciting new book entitled, Nature Wants Us to be Fat. We will be discussing his new book today on the podcast. As many of you will note, this is Dr. Johnson’s second appearance on the program and we will consider this to be an important “part two,” picking up where we left off last time in his brilliant elucidation of this newly discovered, central player in metabolic diseases, uric acid.
On a personal note, over the past year I’ve gotten to know Rick very well, and I absolutely cherish our newfound friendship.
I also explore uric acid it in my new book, Drop Acid, but to be clear, the incredible body of research belongs to Dr. Johnson. And this is the reason that readers of my new book will note that it is dedicated to Dr. Johnson as my way of honoring him for his incredible body of research that clearly is helping, and will continue to help so many people moving forward.
====
Dr. Richard Johnson is a Professor of Medicine at the University of Colorado and is a clinician, educator, and researcher. He is board-certified in internal medicine, infectious diseases, and kidney disease and is the founding editor of Comprehensive Clinical Nephrology, one of the main textbooks on kidney disease. For more than 20 years, he has led research on the cause of obesity and diabetes, with special interest in the role of sugar (especially fructose) and uric acid. His research has been highly cited, published in top medical journals, and supported by grants from the National Institutes of Health. He is the author of The Sugar Fix and The Fat Switch. His latest work contains state-of-the-art discoveries on the cause of obesity and potential cures.
___________________________
Instagram: / davidperlmutter
Website: www.drperlmutt...
Subscribe to our channel:
/ @davidperlmuttermd

Пікірлер: 624

@DavidPerlmutterMD 2 жыл бұрын

If this material feels unapproachable, or you're interested to learn more. consider checking out Drop Acid: www.drperlmutter.com/books/drop-acid/

@mimiedwards7791 2 жыл бұрын

Hi Dr Perlmutter. I’ve followed you and young Austin for a few years now. Great discussion. I’ve preordered yr book. Can’t wait. God bless you for your work.

@juliametcalf2660 2 жыл бұрын

You seem to be normalizing the necessity for complex drugs ....drugs have become a pervasive evil in modern society ...it's ALL diet

@ronroesler7555 2 жыл бұрын

Dr Perlmutter, am I confused, but I thought uric acid is a result of eating carbohydrates and other plant products? Am I confused? It seems to me that the question is: what caused the inflammation and the excess of uric acid. Does he find giving insulin causes blood sugar to go down for a bit? How about giving other drugs that treat symptoms? Am I missing something or is this another treatment of symptoms instead of eliminating the cause?

@ronroesler7555 2 жыл бұрын

Who is this guy? He needs to do a little reading of recent research.

@ronroesler7555 2 жыл бұрын

I can’t help but wonder if Dr Johnson would be interested in knowing that there’s a correlation between elevated blood sugar and diabetes? Maybe he would suggest lowering blood sugar to help diabetes! Maybe injecting insulin could lower blood sugar this lowering diabetes?

@bellakrinkle9381 2 жыл бұрын

My mother had kidney stones later in life; she checked herself out of the hospital after reading Eba Wayland's book, on nutrition. Not sure of the correct name; she lived in Europe and now I believe her work has been banned, along with many other early and present day researchers. Mom changed her diet and within months, cured herself, and did not need surgery! This was in the 1960s. She died at age 107 years by eating healthy!

@mr.c9553 2 жыл бұрын

Any chance you can elaborate on the book you mentioned ?

@grainofsand4176 2 жыл бұрын

Id ike to know the book too. Thanks

@momzilla9491 2 жыл бұрын

Hi Bella, Like Mr. C and GrainOfSand, I would like to know anything more you can tell us about Eba Wayland's book on nutrition. Incidentally, kidney stone sufferers should buy "Chanca Piedra". I had K.S.zzz about 6 years about when I was in my mid 50s. Terrible, terrible pain. Would rather have another baby... I was told about Chanca Piedra (means Claw in Spanish?) 3 years ago, and when ever I feel "that " pain, I take two immediately. No more pain!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! You can buy it at a health food store. Bottle says 500mg, vegan, non-gmo, gluten free. "Improves urinary tract health" Now I'm wondering if Chanca Piedra lowers uric acid!

@momzilla9491 2 жыл бұрын

Bingo! Chanca Piedra has a direct effect on Uric Acid and is taken as a cheaper alternative to Uricase! See KZfaq "How This Herbal Supplement Prevents Kidney Stones" Gee I love this Dr. Johnson. I could listen to him all day. My thanks to Dr. Pearlmutter for having him as a guest on the show!

@grainofsand4176 2 жыл бұрын

@@momzilla9491 thanks

@scottporter6373 4 ай бұрын

As a physician who graduated from medical school years ago I happended upon this knowledge by accident in studying low carb/carnivore diets. This is life changing, for me and my patients. I cannot believe the studies have been around for quite awhile, yet are virually unknown. Dr. R. Johnson deserves a Nobel prize for his work. Doctors are taught nothing of nutrition in med school. Over the last two years, I have been on a quest to seek proper nutrition, metabolic health and the causes of the rampant Diabetes, HTN and CVD I see in almost every patient. This is likely THE fundamental link in the chain. Everything I was taught in med school was wrong. Now, I have found out that saturated fats are GOOD, PUFAs/Seed oils bad. Statins bad, Cholesterol good. Food pyramid...a sham and making us sick. Big pharma and the food industry has americans scammed. My journey began with the Low Carb Down Under youtube videos and Dr. Paul Mason. But this revelation on Uric Acid is the quintessential element to the basis of a new revelation on nutrition and health.

@1607rosie 2 жыл бұрын

This is very eye opening for me. I take allopurinol and for high Uric acid . Even while losing weight they check my Uric acid. I knew sugar was bad for diabetes but didn't realize the relationship between Uric acid and insulin and insulin resistance.

@andrewwong2605 Жыл бұрын

I use to take allopurinol. Than I started taking whole lemon 🍋 everyday some 6-7months ago. I'm 67 and can play tennis for 2-3 hours. I eat everything now and have no joint pain. I'm starting NMN from today.

@wendyhla7097 7 ай бұрын

Eating basil everyday reduces uric acid level also.

@petercyr3508 2 жыл бұрын

I was diagnosed with type 2 diabetes in 1998. My uric acid has NEVER been measured. One more failure of modern medicine. I have successfully been managing my T2D with very low carb/keto diets since diagnosed. No thanks to medicine again. I have been communicating with Dr. J. He is a sweetheart!

@jujuapple6706 2 жыл бұрын

Who is Dr J? Do u mean Dr Jason Fung?

@Absolomthecarnivore Жыл бұрын

Alopatic medicine and modern dieticians with their food pyramid are misleading. The only way I see alopatic medicine useful is in urgency

@dougsmith6635 2 жыл бұрын

Dr. Perlmutter, thank you for bringing Dr. Johnson to the attention of those of us who can't afford what Dr. Attia has to offer. This is great information!

@fignewton8690 2 жыл бұрын

Whole Foods, sunshine, fresh air and water with a little exercise is all we need.

@ridinmabike 2 жыл бұрын

You can listen to a couple of Dr Peter Attia's talks with Dr Johnson for free on The Drive podcast. Fantastic interviews!

@HEARTANDSOULOFMINE Жыл бұрын

I heard the same podcasts by Dr. Attia on THE DRIVE for free! It was jaw dropping, especially the relationship of excessive salt and its conversion to fructose, which was not addressed in this interview.

@seekerout 2 жыл бұрын

A fascinating account of true scientific enquiry. It's like a detective story, and at the heart of it is a mind full of curiosity.

@BR-hi6yt Жыл бұрын

Makes sense to me too - who'd have thought? - Uric acid increase from fructose consumption. Then high uric acid causing hypertension. Thx so much you two guys.

@CelineNoyce 2 жыл бұрын

This is absolutely a revelation. In particular... the information / theory about how your natural instinct to survive could be making you absent minded... which then becomes dementia. Of course. that does make sense. I have heard Dr Johnson before but too often the interviewer will not allow him to just spew his knowledge... you did, great info resulted.

@annethomas9302 2 жыл бұрын

I remember when I reduced sugar intake there was a huge change in my anxiety.

@abdelilahbenahmed4350 2 жыл бұрын

please what do you mean by sugar : added sugar or also whole food fruit intake ?

@beniirama4076 2 жыл бұрын

both of them

@versewriter8123 2 жыл бұрын

Did your anxiety increase or decrease when you lowered sugar in your diet?

@alexk48 2 жыл бұрын

Your blood sugar was probably more stable. Early in insulin resistance one actually becomes hypoglycemic.

@Needless2say Жыл бұрын

Beri beri is not the name of a fruit flavored candy, that would be Berry Berry. Got B vitamins? It's interesting that sugar also consumes potassium and zinc as it gets processed in the body. Thanks Dr Eric Berg and EO Nutrition.

@gerrym-cat7119 2 жыл бұрын

What an enlightening conversation (to say the least)! Thank you both 🙏

@jbwentworthe6082 2 жыл бұрын

There appears to be "fructose" added to just about all the packaged food products we have been using for years. Even the packaged high "protein" Beef Jerkey product we have considered an energy booster is flavored with "fructose".

@nancyfahey7518 2 жыл бұрын

I'm severely allergic to corn. Normally I can taste it. But if it's well hidden I feel it in my bones and joints within a half hour. Yes, it's in everything. Corn syrup.

@emh8861 2 жыл бұрын

Exactly, it raises my blood sugar and makes me itch like crazy.

@pendafen7405 Жыл бұрын

Yes, even vitamins! My last multivits contained it, for some ridiculous reason.

@catmate8358 Жыл бұрын

In 2016 I was diagnosed with osteoarthritis. Lab results showed elevated uric acid so my doctor gave me dietary instructions intended for people who suffer from gout. Basically, it was aimed at reducing intake of purines. Now, I am a meat eater and can hardly survive without meat. Otoh, I have already been on a reduced carbohydrates diet and close to zero refined sugars. No fructose syrup is used where I live. So I was directed to reduce meat intake. The food that was deemed safe was carbohydrates that I despised. In a rather short period of time I managed to reduce my uric acid by dietary measures to very low, but my rheumatic pains persisted. Now, it is very possible that I had high levels of uric acid for many years but didn't know it as it has never been measured. It is of note that I started suffering from digestion problems three years prior to developing osteoarthritis. These digestion problems were not taken seriously by the doctors who simply said it's irritable bowel syndrome. I was very puzzled and still am to this day as to what caused those digestion troubles as I didn't smoke, barely drank alcohol, avoided refined sugars and limited other carbs, ate sufficient fruits and veggies and was reasonably active. Possibly ate more protein and drank less water than necessary. So, I while I think that corn syrup is certainly bad and should be banned, it cannot be the only cause of elevated uric acid. There ought to be other factors at play.

@wandascinto6386 9 ай бұрын

There is: cAndida and sibo drive uric acid levels up.

@bethbrockman3670 6 ай бұрын

sibo??

@BL-rb7jm Жыл бұрын

when I lived on the farm in the late sixties and 70s I worked hard and walked 6 miles daily to see a friend and back. and ate from the garden and had well water. I was not fat. I had no gout. we never ate anything artificial or had sprays on our fruit trees or in our vegetable gardens. I get up early as the sun rose and went to bed when the sun sat. i never had a need to have a curtain nor did we locked our doors. we had dogs cats and pet monkeys. I always had a deep sleep. never took any medication. when i moved out of home left the garden ate at fast foods and stop living off the land and i got gout. i gained 40 lbs. i developed acne. and i got a ton of cavities even though i go to the gym and walked still and brushed my teeth. it wad coming to the city that changed my life. and yes i started to drink beer and pop etc. then i was told to eat margarine and no salt.

@lynlawley8903 Жыл бұрын

Margarine is a bad food that clogs arteries,,,,,

@lilydauber3147 Жыл бұрын

Dietary Guidelines for Gout Prevention and Treatment Avoid very high purine foods and limit high purine foods to not more than a serving per day (see chart below). Avoid meat extracts, broths, bouillon and gravy. Avoid rich, high-fat, meat-centered meals. Rely on plant foods as your primary sources of protein. Eat several servings of fiber-rich plant foods such as whole grains, vegetables, fruits, each day. Minimize intake of refined carbohydrates, including both starches (white flour products) and sugar. Concentrated fructose can increase uric acid levels and increase insulin resistance. Drink 2-3 L of fluids each day. Most of this should be water. Avoid alcohol, as it tends to interfere with uric acid excretion. Maintain a healthy body weight. If you are overweight, aim for a slow gradual weight loss of ½-1 kg (1-2 lbs) per week. Rapid weight loss from fasting or severely calorie-restricted diets is not recommended as this can raise uric acid levels and aggravate gout. Increase your physical activity. (Check with your doctor first if you are currently not active).

@martywilliard 6 ай бұрын

Your’s was the Garden of Eden. One we all will live like you did

@Marx1963 2 жыл бұрын

Pre orders book ! Great info - made me get Uric Acid checked immediately! 4.2 in a 4-8 range ! I’ll assume I’m good . Meat based diet -No sugar No Grain !

@DavidPerlmutterMD 2 жыл бұрын

Thanks for pre-ordering!

@andressuva3068 2 жыл бұрын

Thank you for information Dr. Richard and Dr. David. I agree with you Dr. Richard since I controled my carbs and fructose I reversed my diabetes and my uric acid is normal now. Thank you again both of you are brilliant Doctors.

@vlastafe 2 жыл бұрын

Oh my, I had a gout attack without knowing. My joints hurt constantly. Also blood pressure is higher. Listening carefully

@AlanWil2 2 жыл бұрын

My blood pressure was high for the longest time. When I changed my diet to low carb, high fat, and lots of meat, in 30 days my BP became normal...110/60. WOW!!!

@intrinsicfactor5425 2 жыл бұрын

......normally high blood pressure is simply a potassium deficiency. Potassium dumps sodium out of the body and so will being on a Keto regiment. Lack of potassium will normally retain too much salt which in turn retains too much water which in turns causes high blood pressure. If you remain on Keto you will need to monitor your salt and potassium levels. If you ever feel like you have brain fog, it is a lack of sodium when on Keto. Keto brain fog and what is called Keto flu (bacteria/fungi die-off) are different. Also, persons who are blood type O will generally do better on Keto than blood type A individuals.

@daviddebilov2301 2 жыл бұрын

Same happened to me on a whole food, plant based diet.

@nancyfahey7518 2 жыл бұрын

@@intrinsicfactor5425 I'm far from being a professional but there is something wrong with what you're saying. Keto for 4 years and all my blood work was fine. Twice as much pink Himalayan salt as potassium, magnesium plus a fair amount of calcium rich food. 110/70 is my norm. No swollen ankle anymore. No panic attacks. No more neuropathy. Something is going right for this 66 year old.

@Antipodeano 2 жыл бұрын

@@nancyfahey7518 Yeah, don't listen to internet commentators, listen to Doctors, especially specialised ones like the one in the video.

@enigmatistic8470 2 жыл бұрын

@@nancyfahey7518 As an addendum: most people are unaware the RDA for potassium was very quietly cut in greater than half from 5700mg to 2300mg. Optimal sodium range studies still place longevity between 4 to 6 grams (4000mg-6000mg). For whatever that is worth to you. 😉

@wocket42 2 жыл бұрын

Fantastic. This is the link I was missing to understand insulin resistance and when it was useful to the body.

@flowgood123 2 жыл бұрын

What does keto, carnivore,vegan and fruitarian have in common, they all stopped eating processed foods.🤔🙂

@wendycarter5718 2 жыл бұрын

How vegan ????? The vegan diet would include cakes , biscuits , pastas ,sugars ,seed oils etc!!!! Actually the vegan diet pretty much depends on crap food !!!!!

@lilydauber3147 Жыл бұрын

@@wendycarter5718 Vegan junk foods are the same as ultra-processed foods! Eat only Whole Foods plant-based to preserve health. Many scientists and doctors have performed numerous studies to support the benefits of a WFPB diet for various chronic diseases, including Type 2 diabetes and coronary artery disease.

@lilydauber3147 Жыл бұрын

@@wendycarter5718 whole food plant-based (WFPB) diet is an excellent choice to help with gout. Uric acid from purine breakdown is helped by a WFPB diet because plants have MUCH lower levels of purines.

@okeke4811 2 жыл бұрын

Thank you very much for sharing it!! I am privileged to be able to witness a conversation of such brilliant minds, for me it has an incalculable value, you have made my day. Thanks again!!

@ClassicJukeboxBand 2 жыл бұрын

I'm probably the biggest cheerleader for Dr Johnson, ever since I saw him on Mercola videos years ago. The reason I like his theory on obesity is because his is the only one that makes evolutionary sense. I have known the dangers of fructose and high uric acid for years, thanks to him. Dr Johnson is even more of an expert on fructose than Robert Lustig, and I wish I could nominate him for a Nobel prize...

@CelineNoyce 2 жыл бұрын

One of the things I hate about medicine is when they tell me something which doesn't seem to make sense with what we know about nature. I actually do think his thoughts on salt is one of those... since I don't see Bear's searching for high salt prior to the winter.

@ClassicJukeboxBand 2 жыл бұрын

@@CelineNoyce Dr Johnson says that high salt blood concentration is a problem, not just high total salt. He says that if you eat something salty to drink water to lower the concentration because high salt concentration can lead to obesity, but it's a much slower process.

@michaelthomas7178 2 жыл бұрын

CP Kelco Okmulgee Oklahoma a high fructose GMO corn syrup food additive processing factory, is directly responsible for obesity and diabetes epidemic in USA. Parent company is Monsanto, which owns Phramcia which makes drugs to treat diabetes and associated obesity conditions. A circle of human manufactured disease for profit. This is a crime against humanity.

@meman6964 2 жыл бұрын

Monsanto now owned by Bayer, a German company. Full page ads in Wall Street Journal tell how Bayer is all for helping human life.... but they stil make Round Up and engineer seed to monopolize crops. Evil

@brianebanks213 2 жыл бұрын

Such a sad state of affairs, where a set of tyrants skillfully evade prosecution, manipulate and mislead our governments which many times are a part of the blatant crime against humanity. Destruction of their fellow human beings for God sake, in the name of the all mighty dollar.

@thebiblepriest4950 Жыл бұрын

Thank you, doctors. I have tried to control my gout attacks over the past two decades by avoiding high-purine foods, with mixed success. Then three months ago my left hand suddenly swelled to three times normal size and I was forced to consult the professionals. My uric acid level was 8.7, glucose 245 (after fasting) and hemoglobin 4.6. So I submitted to a strict regime of prescribed pills and controlled diet, emphasizing liver-healthy foods. My readings last week were uric acid 4.9, glucose 108 (after not fasting) and hemoglobin 4.1 -- along with losing ten pounds. So it is amazing what improvements can be made in a short period of time with a combination of the right medications and dietary discipline. Your book Drop Acid (which I got last Fall) helped lay the groundwork of understanding what needed to be done to restore my good health. Thank you both for your lives' work.

@pdales2257 Жыл бұрын

Thank you for the good information. Did you follow the diet in drop acid book? I kind of have the same problem is that I'm not a drinker and I don't eat fast food and I have sugar on occasion. But I believe glucose levels due to eating bread pasta foods that elevate those levels are contributing to those higher uric acid levels. Did you find that to be true with specific foods that are not necessarily bad carbohydrates like pasta and bread?

@thebiblepriest4950 Жыл бұрын

@@pdales2257 It was Christmas that nearly killed me: I got a gift certificate for meats and bought side pork and pork chops: I got a several cookie platters and sampled them all. Yes, I was totally out of control at Christmas time. Do you think I could go into solitary confinement next December?

@wandascinto6386 9 ай бұрын

I’m popping 12.0 and 10.3’s

@jeffgoldsmith1679 2 жыл бұрын

This was very informative and helpful as a life long gout sufferer. I hardly ever drink, exercise all the time but have struggled with fructose. I need a daily or weekly test kit to help stay dialed in. I am severely restricting Carbs and cutting fructose and alcohol out entirely. I shall see. ? Thank You Dr. Perlmutter

@HEARTANDSOULOFMINE Жыл бұрын

Also lower salt intake. Dr. Johnson's research indicates excessive salt converts to fructose.

@waffle_chair9269 Жыл бұрын

Salt can often appear to be a problem when potassium and or magnesium are deficient. It’s not always the actual salt, but rather the imbalance of importer ratios. Think sodium potassium pump.

@shanearmstrong9618 Жыл бұрын

@@HEARTANDSOULOFMINE please help me out with salt intake ? Some of the guys I listen to say sea salt , Caltic salt , etc are not bad for us .

@pdales2257 Жыл бұрын

@@waffle_chair9269thank you great information!!!

@lolybird77 11 ай бұрын

Where do you get a test kit??. I need this!!!❤

@user-ej4us4bd3p Жыл бұрын

Now I understand why I have gout in my pinky and elevated blood pressure. Thanks for making me understand my own body.

@eshaniking4421 Жыл бұрын

Throws so much light - thank you both for an incredibly interesting discussion 🙏

@catjoo4485 2 жыл бұрын

Phenomenal story of the detective work and research that has resulted in such an important discovery that uric acid plays a key role in driving metabolic syndrome. I can't wait to read your books! Timely interview as I have been doing my own research lately for answers due to my father having greater frequency and duration of gout attacks in the last several months. Thank you so much for your groundbreaking research🙏

@snowbird6855 2 жыл бұрын

Go for celery juice and sour cherry juice (no additives) daily for gout as well as dropping red meat and red wine.

@lawannameeks4106 2 жыл бұрын

Happy

@lawannameeks4106 2 жыл бұрын

Happy

@lawannameeks4106 2 жыл бұрын

Happy

@lawannameeks4106 2 жыл бұрын

Happy

@TheKetoSurvivor 2 жыл бұрын

Fascinating and mind blowing! 🤯 Thank you both for your head work!

@bernadettebecher5668 2 жыл бұрын

Outstanding presentation- thank you for this podcast. Cannot wait to share this information.

@DavidPerlmutterMD 2 жыл бұрын

Thanks for watching! Glad to know you enjoyed.

@mptrader1620 2 жыл бұрын

A few questions, which brand Uric Acid home self test is best. How long did it take for the Uric Acid to go down when you stopped eating sardines (I also have been eating them every day). How much Quercetin to take and should you take it with anything else? Thanks

@robinengland5799 2 жыл бұрын

Preordered Dr Johnson's book! Amazing information. Dr Johnson has an amazing ability to bring the very complex to the lay person. Thank you for this lecture.

@tonyknight9912 2 жыл бұрын

Brilliant, brilliant work by an exceptional doctor and researcher !

@granitabirg7950 2 жыл бұрын

Thank you so much for sharing this conversation.It is really really interesting and very informative. God Bless you all.💖💖

@mariorodriguezjr.4960 2 жыл бұрын

Hello...... My name is Mario Rodriguez.. it will be so nice if I have you as one of my subscriber 😊... Thank you

@krustysurfer 2 жыл бұрын

Most excellent information, sorely needed and very understandable to the layman. The sugar uric acid relationship to insulin resistance is plain to see and is easy to fix, STOP eating carbohydrates and fructose and the problem will fix itself! Thank you doctors you are saving lives with your research and God bless you for sharing your wisdom and knowledge with the world.

@tommyjoe4310 2 жыл бұрын

What would be a few examples of dietary recommendations of what we should be eating to replace the carbs and fructose in the fruit

@rhondawills1123 2 жыл бұрын

@@tommyjoe4310 You don't need to replace either. Your body does not require carbohydrates to exist and fructose is sugar. Sugar is toxic to our bodies. If we were able to look back in time, we'd find a time when humans started experimenting with our fruits and criss-breeding, e.t.c. to make them more full of sugar than when God created them. The banana has been modified so much its ridiculous - and then they turn around and say ... eat bananas. They have potassium. I think it's around 343MG. Our bodies need 4700MG of potassium daily. One current day banana is a small dent in that big number, and jacks our blood sugars levels up considerably.

@tommyjoe4310 2 жыл бұрын

@@rhondawills1123 does not leave a lot left to eat. He said to avoid red meat too. What's left

@lonajensen2203 2 жыл бұрын

@@tommyjoe4310 0

@sunberry74601 2 жыл бұрын

I have been keto a year still having gout flare ups. Finally went on 300 mg of allpurinol. My number 6.7 in Jan and won’t be tested again till next Jan. But it had come down from 7.7. I keep my carbs at around 20 a day and eat no sugar .

@skyla11 2 жыл бұрын

Always had high BP (had an atrial.fibrillation issue in May probably due to stopping meds), but now back.on.meds and having a big toe joint pain. Thanks for this great advice. Will def try to reduce this uric acid. Much appreciated.

@mariorodriguezjr.4960 2 жыл бұрын

Hello...... My name is Mario Rodriguez.. it will be so nice if I have you as one of my subscriber 😊... Thank you

@JoeBizzle 10 ай бұрын

I've been saying obesity is a survival mechanism for 10+ years. Now I know more about HOW it works. Thanks Doc!

@jpridie 2 жыл бұрын

Very interesting lecture thank you for making it public I’m on a keto diet and still got gout and my blood sugar is hard to control so this lecture helps me make better choices.

@gwens5093 2 жыл бұрын

These are some natural solutions that can help you with gout: 1. It turns out that baking soda is an excellent remedy in cases of gout. Create a mixture that contains half a glass of water and ½ teaspoon of baking soda. Drink it every day. In case you are dealing with gout attacks, you can use one teaspoon in this solution. 2. If you keep your body’s environment alkalized, you will be able to protect it from the negative effects of gout. That’s why you must increase the intake of alkaline drinks and foods. One good example of a drink like this is lemon juice. It can prevent the buildup of uric acid crystals. Take half a lemon and squeeze it in one glass of lukewarm water. Drink this beverage in the morning before breakfast. 3. In addition, apple cider vinegar is a type of vinegar that can boost the alkalinity in your body mostly because of the fact that it contains malic acid. This specific type of acid dissolves uric acid and removes them from the body. Take one glass of water (200 ml.) and pour one tablespoon of organic apple cider vinegar. Use this mixture twice a day, before your main meals (dinner and lunch). When it comes to foods that prevent gout, you can rely on these three foods: Curcumin is the active ingredient of turmeric and one of the main reasons why this spice is so healthy. Curcumin protects the kidneys and comes with strong anti-inflammatory properties too. Pineapples have another active ingredient - bromelain. Bromelain provides powerful anti-inflammatory effects and acts as an analgesic agent too. Finally, flaxseeds provide numerous health benefits and they also have the ability to lower the uric acid levels in people.

@fairenough7984 2 жыл бұрын

I got a kidney stone after being on keto 4 weeks. Really not fun.

@lynnwilliams5432 2 жыл бұрын

It is your body making fructose!

@skyaboveearth6622 2 жыл бұрын

@@gwens5093 Excellent advice Thank you

@jr.6199 2 жыл бұрын

@@gwens5093 What references do you have for your medical claims? Others here- never take medical advice from the Comments section before talking with a doctor who knows your history and offer them the research before treating a disease with this info here!

@bonnieo8 2 жыл бұрын

Dr. Johnson has such important information to share! This interview was a bit of a disorganized mess compared to Peter Attia’s interview on The Drive, or even the one on HVMN.

@SibleySteve 2 жыл бұрын

This is awesome. I had gout a few years ago. I have lost 45 pounds since then and stopped drinking beer. No more gout. In trying to lower my purines I also lowered my fructose consumption. Funny thing is, when I got gout, my uric acid was not THAT high, it was around 6. Maybe it was the fructose.

@michaelthomas7178 2 жыл бұрын

It is fructose, see doctor Ken Berry you on gout.

@enigmatistic8470 2 жыл бұрын

View Dr. Robert Lustig on fructose.

@mirelladay2930 2 жыл бұрын

Don't interrupted him. He loose his thoughts of speech.

@KevinMcCaffreyfingerstyle 2 жыл бұрын

I hope this video proves instrumental and finding the real reason for my long-term hypertension I'm over 65 and it's starting to take its toll I want the problem solved I'm going to look further thank you Dr perimuter

@michaelthomas7178 2 жыл бұрын

@@KevinMcCaffreyfingerstyle I eat a lemon a day to reduce blood pressure.

@scout3444 2 жыл бұрын

very interesting. Thankfully, scientists are developing humane alternatives to animal tests. New non-animal methods are quickly and regularly becoming available. This doesn't mean halting medical progress. Instead, replacing animals and using non-animal testing methods is aimed at improving the test quality *as well as the humanity of our science*. Most people are against animal cruelty but think there's no other choice. If we can live happy healthy lives without harming others, why wouldn't we? Best to you,

@deeandrews7051 2 жыл бұрын

Totall agree. Animals are living, breathing sensient beings and feel pain and suffer. The sooner they stop doing cruel experiments on them, the better.

@alexk48 2 жыл бұрын

I am so glad you are both anti abortion.

@lynnfarley7859 2 жыл бұрын

Wow.. dealing with a kidney stone now - my ears open.

@DavidPerlmutterMD 2 жыл бұрын

Glad this information could be timely. Hope it's useful as well!

@victorlunga6743 2 жыл бұрын

I normally suffer from acute gout attacks on a background of type 2. Diabetes, I don't have high BP , sugar is controlled, what diet should I eat and what should I do to keep the uric acid at bay.

@tarikcamacho Жыл бұрын

Amazing good interview. I believe all points of my curiosity about the subject was explored here. Thank you very much Dr. David for this important work you did here with Dr. Johnson. My gratitude

@michaeljgeiselman9450 Жыл бұрын

L0RI no

@michaelrekow1507 2 жыл бұрын

I appreciate this video but this information has been shared for decades and clearly understood by Naturopaths world wide .

@ASouthernLadyinAppalachia Жыл бұрын

The problem is the general public and regular MD’s DON’T know it or see Naturopaths.

@wellnesspathforme6236 2 жыл бұрын

Mitochondrial burnout / high oxidative stress. Bio-copper, magnesium, retinol, and sunshine are key ingredients to energize mitochondrial (cellular energy) function. Metallic iron filings throw an iron monkey wrench in the system.

@levisinner2694 2 жыл бұрын

I don't understand. Brazilian doctors have been recommending lowering uric acid for ages. I thought the effects of uric acid on humans was common knowledge worldwide

@lynlawley8903 Жыл бұрын

Not here in England I dont think

@conniesmith4108 2 жыл бұрын

🤗thank you both, for sharing this very valuable information...shared with friend, family 💜💜💜

@faisal-ca 2 жыл бұрын

I have seen benefits of containing Uric acid using herbal remedies and will consider Alopurinol if it doesn't help. Planning on taking Uric Acid readings soon.

@rustybolts8953 2 жыл бұрын

If KZfaq had a slider instead of a like button, I would give this video a 10.+

@jondor654 Жыл бұрын

Not so rusty. Good idea

@bevcoyne6632 2 жыл бұрын

Clever title ! Many thanks for this wealth of knowledge ,

@tomhennessy7276 2 жыл бұрын

"Uric Acid as a potential cue to screen for iron overload"

@1607rosie 2 жыл бұрын

I was real curious on what things I should eat ti lower my Uric acid. And not to eat.

@lilydauber3147 Жыл бұрын

@golflouis52 2 жыл бұрын

Great video, thank's a lot... very educational and entertaining in a paleo point of view of the human genome mutation in regard to uric acid.. 👍🙋‍♂️🎈

@alvinrussell9747 2 жыл бұрын

my uric acid has been lowered it had no effect on my blood pressure at all,i have 3 doctors on this did have gout it has taken them 2 years too get gout down did all they said to do my uric acid was around 6 i do not consume alcohol at all for over 25 years at all !!!!! what do you say about this ?

@lizardfirefighter110 2 жыл бұрын

Damn two more books to add to my reading list. I am looking forward to the new book “Super Gut” by William Davis MD, as well.

@DavidPerlmutterMD 2 жыл бұрын

Lots of great material out there, yes!

@waffle_chair9269 Жыл бұрын

Ikr !! 😂 the lists just keep getting longer😂

@T-aka-T 2 жыл бұрын

Fabulous interview. Better if Dr P doesn't interrupt the flow to superimpose a question/restatement of what he is saying. The story is complex but RJ is very clear indeed. Just let him go. He doesn't need clarification.

@christylumpa4357 Жыл бұрын

I totally agree about the interruptions.....not good.

@allenjames6743 2 жыл бұрын

Knowing the hypothesis concerning lack of uricase in gout patients, why can’t medical experts develop treatments that address the issue, aside from using alliopuirinol ?

@lynlawley8903 Жыл бұрын

I was told that cherry helps

@doriscastillo2232 Жыл бұрын

Allopurinol is toxic to your liver and kidneys. The antidote to your high uric acid is to hot compress while drinking coconut water or lemon grass tea.. Greetings all the way from Republic of Ireland filipino

@jaygamilwatson8529 Жыл бұрын

Lemongrass will exacerbate a gout attack 😢

@richardcates8605 Жыл бұрын

The treatment is correct diet.

@WeighedWilson Жыл бұрын

Doctors don't make kickbacks on spinach.

@7aloha7 2 жыл бұрын

I have Stage 5 CKD. If I have sugar in the form of cookies, cake, soda!, Etc. I am guaranteed to have a gout attack. I am normal weight with normal blood pressure but tend to have high uric acid.

@lynlawley8903 Жыл бұрын

Oh so not sure wish we could ,,sort things out for every one

@marzymarrz5172 Жыл бұрын

I love the description of his process of inquiry.

@liwallace4867 2 жыл бұрын

I wonder aside from changing diet, what available supplements and/ or medications can give you a kick start blocking Uric Acid formation, may be available to general public..

@bluelotus7824 2 жыл бұрын

Bicarb soda, apple cider vinegar, quercetin.

@lynlawley8903 Жыл бұрын

One person said qwertacine I'm not sure

@jillmareetawhai6041 Жыл бұрын

I have given my husband who gets gout from sucrose java tea, have had amazing success, his uric acid levels have dropped dramatically

@ricgordon6627 2 жыл бұрын

Go immediately to 1:10 to hear practical dietary advice.

@bernardlunn 2 жыл бұрын

Thanks

@edmundjordan 2 жыл бұрын

So my takeaway is sugar, fructose, yeast in beer raise uric acid. Uric acid contributes to obesity, high blood pressure, high blood sugar, gout, and metabolic syndrome. The cure was not mentioned other than dont eat fructose, sugar, drink beer. But I know tart cherry juice or capsules is one treatment. Tks for the info.

@ekraszewski 2 жыл бұрын

@Taiwo Omotosho R.W. Knudsen makes an organic tart cherry juice with no added sugar. Trader Joe’s also carries tart cherry juice that has no added sugar. I have seen the juices of which you speak. They are not the juices once should drink for gout or anything else for that matter.

@TexasRain45 2 жыл бұрын

Thank you for the run down didn’t have time to listen.

@lynlawley8903 Жыл бұрын

That makes me wonder they are now saying that cancer is a metabolic disease,,,,I've been doing everything wrong now have breast cancer,, also had ,,d and sleep probs,,lots of illness can be interlinked,, but missed ,,,

@dagmarvandoren9364 10 ай бұрын

No beer....oh lord...no beer. No wine...nononono

@pepper24able 2 жыл бұрын

Just had my first gout attack aged 70. Horrible. Thanks for your insight.

@skyla11 2 жыл бұрын

Yes me too. Drinking list of R.O. water. No tap water.

@pepper24able 2 жыл бұрын

@nigwasme So I got rid of the evil gout in two days (well the worst of it). Drank loads of water with a pinch of baking soda in it. I have read that making tea out of blackcurrant leaves is good for removing uric acid. Also soaking feet in a brew of the leaves. Plenty of that on the farm so we will try to incorporate that in my future days. I figure I had been working hard for two straight days with only a coffee in the morning for hydration. That probably set the thing off!

@pepper24able 2 жыл бұрын

Okay, so the black currant leaves are a go. Love the tea. I take 12 leaves, wash them and break them up. Put them into a two cup mug. Pour over boiling water and let it sit until cool. This has helped my aching feet and toes a lot. If I feel stiff and sore in my body, this tea helps a lot. Looking at adding devils claw. Also vitamin C and msm. I am never taking pharmaceutical help. That is is a downward spiral.

@lynlawley8903 Жыл бұрын

@@pepper24able can you put the leaves to freeze so you have some left

@pepper24able Жыл бұрын

@@lynlawley8903 Easier if you dry them. Apparently, nettles and holy basil also help. I also had very high blood pressure so drink a tea of celery seeds and juniper berries. Blood pressure is down to normal. Celery seeds also help with gout.

@versewriter8123 2 жыл бұрын

Does this mean fruits are contraindicated whilst eating a healthy diet? I love fresh fruit - I eat tons if it!🤯

@lynlawley8903 Жыл бұрын

Think it's how much too much is bad,,,it turns to sugar and triggers isulin resistance is that ah I'm not totaly sure this can cause knock on affects,,,like gout ,,its all difficult

@lilydauber3147 Жыл бұрын

Fructose is a sugar found naturally in fruits, fruit juices, some vegetables and honey. Fructose is also a basic component in table sugar (sucrose), and high-fructose corn syrup is used to sweeten many processed foods and beverages. High-Dose Fructose Can Cause or Worsen Insulin Resistance (But Fruit Is Okay) High-dose fructose can cause or worsen insulin resistance, abdominal weight gain, fatty liver, heavy periods, and PCOS. What foods increase insulin resistance? These include: Sweetened beverages like soda, regular fruit juices, sweet tea or lemonade. Foods high in saturated fats like whole milk, butter, coconut oil and red meat. Sugary sweets such as candy, cookies, cake and ice cream. White bread, rice, pasta and flour-based foods. Packaged, highly processed foods and snacks.

@lilydauber3147 Жыл бұрын

@@lynlawley8903 What foods increase insulin resistance? These include: Sweetened beverages like soda, regular fruit juices, sweet tea or lemonade. Foods high in saturated fats like whole milk, butter, coconut oil and red meat. Sugary sweets such as candy, cookies, cake and ice cream. White bread, rice, pasta and flour-based foods. Packaged, highly processed foods and snacks.

@jefffrederick8648 2 жыл бұрын

Very enlightening conversation. So grateful for having listened. Is there a home Uric acid testing kit that you would recommend? Also, would you recommend taking Allopurinol for someone who suffers with gout attacks 4-5 times per year?

@truthjoypeace 2 жыл бұрын

Cucumber juice n raw papaya leaf few leaves helps dissolve the uric acid build up.

@lynlawley8903 Жыл бұрын

@@truthjoypeace ooooh where can I check that sj n thanks a thousand it's so help full I eat cellerie and thinking back it seemed to help ,,,, do you know why !!!? Lots of informed people ,,,

@enemchukwunonso4299 2 жыл бұрын

Thank you immensely Dr. Perlmutter and Dr. Richard.

@athenaramirez3546 2 жыл бұрын

No one ever mentions build up oxalates Huge issue for plant based diet consumers

@HammyGirl999 2 жыл бұрын

I agree. This is huge and most overlooked.

@espianmashias9565 2 жыл бұрын

I was a vegan for 6 months and it nearly damaged my body. Never ever again!!!!

@athenaramirez3546 2 жыл бұрын

@@espianmashias9565 I am still going strong I make my own ghee and so I am not a complete vegan I think we need to be flexible And I would like to see less reliance upon meat and dairy for sustenance Once you realize that you have to plan your meals ahead and buy fresh every couple days your circumstances will improve in my opinion Been without meat for 45 years Still going strong

@dmackle3849 2 жыл бұрын

@Athena Ramirez see Sally Norton or Elliot Overton.

@athenaramirez3546 2 жыл бұрын

@@dmackle3849 . On you tube?

@AlexHop1 10 ай бұрын

Thank you for this informative interview.

@user-ie9ij3zk4u 10 ай бұрын

One of the big challenges about uric acid is that it is a by product of many processes. So it may not be the CAUSE of diseases like gout I get, it may be just a disease 'indicator'

@reporter2078 2 жыл бұрын

Please sum up with bullet points at the end for those of us with little time and less patience.

@carmelgrace6402 2 жыл бұрын

excellent!.. i will surely order the book!

@benikramer5115 2 жыл бұрын

Your research must be true.. I had cold hands, feets , ears and nose,,,high blood pressure..weakness, and. i went to the lab the next morning surprise?? Uric acid at 95% of the range , and I felt already better at that time. Probably it was even higher at nighttime, when the crisis was at its peak. It is related with high CK (Creatine Kinase, probably from my legs, from a hike), maybe it is insuline resistance of the sceletal muscles, in combination with high lactic acid due to the blocking of eNOS in arteries and capillaries , and as a result of the muscle has broken down glutamine for fuel. Thank you, to bring my attention to uric acid!!

@Peter-gu4zc 7 ай бұрын

in January/22 at the end of my 14 days total water fast my Uric Acid went up from 340 to 743. After a month stabilized at 260-300 range. Then, at the end of my 7 days water fast, Uric Acid went up again to 614. Now, with OMAD, it stays at 356. Any comments? Thx.

@Peter-gu4zc 7 ай бұрын

69 y.o. generally healthy, got rid of fat in the liver and pancreas + got rid of IR, lost weight to healthy BMI, no HBP (never), no meds (never), healthy diet OMAD. NMR: High LDL-C large buoyant pattern noticed especially at the end of my prolong total water fast. It looks like LDL-C and Uric Acid go in the same direction during my prolong total water fast. Just finished my 5 days total water fast before Christmas. Will check blood LDL-C and Uric Acid after New Year. I feel very healthy. Big improvement in body strength over last 2 yrs of improved life style. Should I be concerned about Uric Acid spikes - good/bad/indifferent? Thank you Dr. Johnson for you great work and Dr. Perlmutter for providing this great platform. Happy New Year 2024!

@Peter-gu4zc 7 ай бұрын

Very interesting concept of seeing Uric Acid as a signaling molecule. Great information about it in your other podcast Dr. Perlmutter (Distressing Effects of High Uric Acid in Human Body | Align Podcast w/ Dr. David Perlmutter M.D) It helps me to understand behaviour of Uric Acid in my body.

@jimbeaver27 2 жыл бұрын

healthy keto is the way to go, eat the highest quality you can afford, eat a variety of real foods, you will get healthy, the human body is amazing

@lilydauber3147 Жыл бұрын

@jimbeaver27 Жыл бұрын

@@lilydauber3147 I do not believe the dietary guidlines sorry

@demotkt2357 2 жыл бұрын

4:48 people with high blood pressure has low grade inflammation in their *kidney*

@darrylknight2675 2 жыл бұрын

I have a parathyroid problem which means that the calcium in my blood is very high. I have read recently that a malfunctioning parathyroid gland can also cause high Uric Acid. Has anyone else read about this link ?

@sandilobianco6734 2 жыл бұрын

Daryl Knight, I have skimmed some articles on this but I need to research more. I have gout. What test did you get to find out about your thyroid? Did you ask for this test? Or did the Dr recommend it?

@lynlawley8903 Жыл бұрын

No but hope they can give you info to help

@lynlawley8903 Жыл бұрын

@@sandilobianco6734 yes as our doctors dont want to follow and we can say we dont know why we have these symptoms then 3,,4 yrs we have major probs

@87solarsky 2 жыл бұрын

A great addition would be differentiating between the gout risks from an animal protein diet vs. the absent risk for gout from consuming plant protein (e.g. chick pea-based produce).

@krzysztofh6308 2 жыл бұрын

It is probably purines they talked about, that you are referring to. And this is basically the amount of cells and nucleic acid which can cause uric acid to go up. Plant protein isolates have few nucleic acids, but so do some animal protein sources like chicken breasts.

@87solarsky 2 жыл бұрын

@@krzysztofh6308 Yes, I meant purines, good point, and thank you for explaining further. Of course there's always the issue of inflammatory potential inherent to the diet, on top of the uric acid level impact, which may then call into question whether a diet incorporating animal protein wouldn't end up being challenged to match those very low inflammatory potential levels commonly found in a gluten-free organic (and ideally fresh) plant-based diet.

@krzysztofh6308 2 жыл бұрын

@@87solarsky if your theory was correct most if not all humans throughout the human history would experience gout😕. We are animal eaters, not plant protein isolates eaters. And if you want to eat anything organic, eat organic meat.

@87solarsky 2 жыл бұрын

@@krzysztofh6308 Well, I do acknowledge that there's a broad-ranging variety of individual dietary choices, all leading to individually different outcomes, based on a variety of internal and external factors, some of which leave little to discuss, with others remaining largely open to interpretation and/or suggestion.

@k8eekatt 2 жыл бұрын

@@87solarsky Yes, my dad had high blood pressure as a side effect of kidney disease and his doctor put him on a low protein diet to protect his kidneys.

@cyclist5000 2 жыл бұрын

What is the difference between high uric acid, and high BUN (blood urea nitrogen)?

@fignewton8690 2 жыл бұрын

Uric acid is formed from the breakdown of purines, some food stuff high in purines could be beer, peas, asparagus, liver and sweet breads. BUN is a waste product produced by the breakdown of proteins thusly called urea nitrogen.

@lynlawley8903 Жыл бұрын

Not heard that befor need to find That info

@lilydauber3147 Жыл бұрын

Serum uric acid was significantly correlated with blood urea nitrogen and serum creatinine. Groups with a higher serum uric acid level had an increased risk of impaired renal function. Urea is the major byproduct of ammonia metabolism in vertebrate animals. Uric acid is the major byproduct of ammonia metabolism in birds, terrestrial arthropods, and reptiles.

@martinlang9615 11 ай бұрын

55:52 just answered my question as to why it’s a good thing to take 500mg Vitamin C per day. I asked this question on another Uric Acid YT video I saw. It all makes sense. Cheers

@elizeleroux6388 Жыл бұрын

I find this topic of great value thankyou

@ryanwolfe7041 6 ай бұрын

What about medications like ace inhibitors raising uric acid? Or niacin?

@MrRainrunner 2 жыл бұрын

Great guest! Thanks!

@DutchmanAmsterdam 2 жыл бұрын

Fantastic conversation. Thank you so much!

@Davidkxf 2 жыл бұрын

Uric Acid is a significant antioxidant. High Uric acid is a symptom not a cause.

@karlawoods2098 2 жыл бұрын

Fascinating. Thank you for your good work.

@elizeleroux6388 Жыл бұрын

a doctor told a man in SA , for his gout , he should take citro soda every morning , at least 2 or 3 times a week , i would in the morning on an empty stomach , to lower uric acid in the blood🎉

@BL-rb7jm Жыл бұрын

Vitamin D deficiency can activate the parathyroid to induce the release of parathyroid hormone, which was thought to increase serum uric acid level, and low vitamin D status may also be associated with risk of CVD. working outside as a kid I got a lot of sun everyday. I also built a ton of muscles. we all should live off the land if possible and stay away from watching t.v. all day like a lot of people do . if you go to bed 2 hours earlier than normal I think that your uric acid will be lowered. we do not live long because we live in the city. our life has changed so much in the last 40 years.

@PJ-xs3jx 2 жыл бұрын

What could be happening with uric acid when the person is in a starvation state due to malabsorbtion and cannot maintain weight, and a tendancy to low blood pressure?

@videnz2664 2 жыл бұрын

i heard many modern fruit is human made and have way more sugar than its natural equivalents in nature back then... i heard the most sweet fruit was as sweet as a carrote

@myteep 11 ай бұрын

Hi, doc.. I suffering from gout attack every 2 weeks. My doctor told just to drink my meds like colchicine once a day. But i dont want to drink meds anymore, or make it less..what is the best way to make my uric acid lower.. And watching your video i supposed that your right that diabetes is also bad for gout sufferers. Is the key here only fruits? How about vitamins C. Can barley grass helps, without taking colchicine? Thank you very much and God bless to both of you doctors..

@TheBhannah 2 жыл бұрын

this is fascinating !

@wandascinto6386 9 ай бұрын

I was doing a detox. My uric acid went up. I got gout in my thumbs which was painful. I had kidney pain and said aaahah it’s. So I started on uric acid pills and drinking a lot of lemon water. Than my kidney felt better but peeing hurt. I’m guessing I had crystals in my urine. I’m 60 have arthritis and I can’t loose weight even on just eating 1 cup of food a day. I’m guessing I’ve had an uric acid and gout my whole life but no dr diagnosed. My brothers autopsy showed gout. My 2 brothers and father died at 50 and 52 of heart attacks.

@TriciaRae 6 ай бұрын

I was diagnosed with gout after a flu shot in 2020. I've also had kidney pain and pain when urinating. Dr. treated me for a UTI. I get it every few months. I was given a free medical reading for Christmas 2023 by a psychic. She informed me that I had crystals in my right kidney. She asked if I had gout! It explained everything! Now I'm going to talk to my doctor the end of the month!

@karadevereux1049 2 жыл бұрын

Excellent information, thank you.

@qingyuhu Жыл бұрын

Amazing information and truly explained the source of our fat epidemic.

@davidg.johnson7574 7 ай бұрын

Doesn't narrowing of the arteries cause hypertension? Maybe there are different hypertensions and uric acid raising blood pressure is another one. Uric Acid also causes problems with erectile dysfunction/ nitric oxide so there is a relation to the blood flow, the same as the narrowing arteries near the heart.