US approves first new Alzheimer's drug in 20 years - BBC News

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BBC News

BBC News

3 жыл бұрын

The first new treatment for Alzheimer's disease for nearly 20 years has been approved by regulators in the United States, paving the way for its use in the UK.
Aducanumab targets the underlying cause of Alzheimer's, the most common form of dementia, rather than its symptoms.
Charities have welcomed the news of a new therapy for the condition.
But scientists are divided over its potential impact because of uncertainty over the trial results.
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Пікірлер: 778
@noobplays-saslow2920
@noobplays-saslow2920 3 жыл бұрын
Even if the Alzheimers drug reduces lifespan I would still have it. Id much rather live 10 years less than live those 10 years not being able to remember or do anything.
@DisticTV
@DisticTV 3 жыл бұрын
Atleast you can decide if you want to have assisted death
@MapleSyrupColour
@MapleSyrupColour 3 жыл бұрын
Having worked in a care home you just become a vegetable near the end of it
@Gaeisok
@Gaeisok 3 жыл бұрын
Yup my granny can’t do anything. She can’t speak she doesn’t move unless someone makes her. I hate to say it but she has already died.
@MapleSyrupColour
@MapleSyrupColour 3 жыл бұрын
@@Gaeisok Its sad but I would rather be dead than in that state of mind
@emilybarrett464
@emilybarrett464 3 жыл бұрын
I agree. I have multiple sclerosis (I am on a DMT to slow it down), but there are certain drugs I need sometimes to help with symptoms. For example, diazepam for muscle spasms. Doctors are so hesitant to prescribe that kinda thing because of risk of addiction, but what’s the point living a longer life if it’s miserable and you’re in pain 🤦🏼‍♀️ x
@G_Silent
@G_Silent 3 жыл бұрын
Alzheimer’s, a soul destroying experience for anyone who is experiencing it or knows someone who is. Any step forward is a big relief for so many.
@legobrickabrac
@legobrickabrac 3 жыл бұрын
It's going to be very disappointing if they don't get the chance to take this medication.
@Tommy2shoe811
@Tommy2shoe811 3 жыл бұрын
Yep I still get chills down my spine whenever I think back to when my grandfather battled and died from it. One episode that sticks in my mind is when he poured piping hot coffee in a glass and severely burned his hand when he grabbed it which caused him to drop the glass which then spilled the coffee all over himself. He ended up with second degree burns on his chest stomach and groin. Immediately after that happened he forgot what happened and became distressed about why he was in so much pain and caused him to go into a mental breakdown. That whole thing wasn’t even one of the really bad episodes it sticks in my mind because I saw it happen and that’s when I realized the gravity of the disease. I was fairly young and didn’t know much about the disease at the time.
@legobrickabrac
@legobrickabrac 3 жыл бұрын
@@Tommy2shoe811 I'm going to watch that new Movie called "The Father" staring Anthony Hopkins on the 20th.
@Tommy2shoe811
@Tommy2shoe811 3 жыл бұрын
@@legobrickabrac I haven’t seen it. I don’t think I could watch it bc it hits too close to home. Alzheimer’s is the disease everyone in my family seems to get. I’ve been screened by my doctor and I’m likely to get it too eventually. Hopefully something else takes me before then bc I don’t want to suffer.
@howmathematicianscreatemat9226
@howmathematicianscreatemat9226 3 жыл бұрын
Good news is we now start to find evidence that our true soul is not only independent of the body but also indestructible. So, it can make us forget things but we keep our identity.
@_mrspanky_4587
@_mrspanky_4587 3 жыл бұрын
Just like cancer, even though the treatment is harmful it's worth it. I'd rather live a shorter life I can remember than a longer one that I forget
@MapleSyrupColour
@MapleSyrupColour 3 жыл бұрын
I completely agree
@vitorfernandes651
@vitorfernandes651 3 жыл бұрын
Once we die we won’t remember anything anyway
@_mrspanky_4587
@_mrspanky_4587 3 жыл бұрын
@@vitorfernandes651 True but our wellbeing affects the people around us too and how they view us. I'd rather be remembered as myself than a hollow shell that once was me
@YoursUntruly
@YoursUntruly Жыл бұрын
Absolutely
@legobrickabrac
@legobrickabrac 3 жыл бұрын
This can't be ignored. If people want to take it then let them.
@lubricustheslippery5028
@lubricustheslippery5028 3 жыл бұрын
Even if we don't know if it makes more harm than good? I had relatives that died in Alzheimers if something that acually helps exists it would be huge. There is also other trials that is interesting going on like testing if herpes virus is at least sometimes a cause for Alzheimers and we have medecin that can stop herpes.
@aidannicholls5149
@aidannicholls5149 3 жыл бұрын
@@lubricustheslippery5028 you have nothing else to lose with Alzheimer’s
@qataribananahamock1495
@qataribananahamock1495 3 жыл бұрын
@@lubricustheslippery5028 how can an approved tested med be harmful? Please understand that this worked on people. Please please stop rejecting science and be an antiscience craphead
@legobrickabrac
@legobrickabrac 3 жыл бұрын
@@lubricustheslippery5028 The thing is this is medication for mostly older people who are around 65 to 75 plus years which I think it is worth the risk to take the drug even if there was some kind of massive side affect in 8 to 10 years. Life expectancy for Men is 75 anyway.
@legobrickabrac
@legobrickabrac 3 жыл бұрын
@@aidannicholls5149 Yes and the age to, the desease mostly affects 65 to 75s plus and as the average life expectancy is 75 anyway.
@mountainblanc3200
@mountainblanc3200 3 жыл бұрын
If it helps then let people decide if they want to take it, Alzheimer’s is a terminal illness anyway, having something that can somehow arrest its progress is a big step forward.
@adithyastren6218
@adithyastren6218 3 жыл бұрын
Overwhelmingly, patents are just not in a position to determine weather a drug is right for them. It is real tempting to pull out the personal freedom guns on this kinda thing, but it is not about that. It is no doubt deeply costly and patience may take it unnecessarily. If it does not work, it should not be sold.
@Sean.R
@Sean.R 3 жыл бұрын
@@adithyastren6218 👍🏻👍🏻👍🏻
@RosieAffleck
@RosieAffleck Жыл бұрын
I wasn’t very impressed with the explanation about why they changed their minds about the effectiveness of the drug. It didn’t inspire much confidence. However, I agree with your comment that if it helps, let people decide. Even if it’s only marginally effective, that can make a big difference for people. Nothing was mentioned about the safety profile for the drug, but there are plenty of drugs on the market with significant side effects that people willingly take anyway because their values as a patient are that the benefits outweigh the risk. The first doctor only cited that the original interpretation of the data was not sufficient, but he didn’t have a good argument for the new interpretation. Research results are very much subject to the method of interpretation and statistical analysis even though we try to make results as unbiased as we can. Also, after FDA approval, drugs are placed in a final phase that basically consists of monitoring and data collection on a mass usage scale. With approval of the new drug, it’s availability (and the immense number of people with Alzheimer’s disease) will allow for better data about whether or not the drug is effective enough warrant it’s adverse reactions. In addition, the new access to the drug allows for more data collection and research to be available, potentially leading to new drugs that work similarly or target the same structures. It would be more difficult to predict mechanisms and adverse drug reactions for “spin-off” drugs if there wasn’t large amounts of data from real patients using the drug. There’s also something to be said about patient individuality and how that varies the effectiveness of the drug significantly due to genetic and epigenetic differences. Large sample size attempts the mitigate these differences, but the reality is that dugs will work great for some people and not great for others. Patients should be allowed the autonomy to decide if they want to try the drug or not, with the knowledge that it might not work for them
@vilmacordero2974
@vilmacordero2974 3 жыл бұрын
If I was diagnosed with this disease, what will I lose if I decide to try this medication? Honestly, my answer will be ‘nothing’. This is hope for many who are afflicted. Whether it slows down the progression for just another year, then so be it.
@twenty2093
@twenty2093 3 жыл бұрын
To be fair I’d prefer any drug against it than no drug against it. 👍👍
@matthewsmith2787
@matthewsmith2787 3 жыл бұрын
Dementia is a horrible disease, if it can help their symptoms and their families it’s a big help
@momentumstocks3493
@momentumstocks3493 3 жыл бұрын
This and M.N.D. are the two I would dread more than anything. I hope they cure both asap.
@Rachel-pz5mo
@Rachel-pz5mo 3 жыл бұрын
Watch this banned on youtube ,Dutch government tell you the Rockefeller (LOCKSTEP) dystopian instruction manual of total top down governmental control for all citizens on earth if you accept the jab. MUST SEE !! vk.com/shilldestroyer?z=video633641290_456239866%2F713dbc0f483a4127ac%2Fpl_wall_633641290
@alexstroud4665
@alexstroud4665 3 жыл бұрын
tbh even though a lot of drugs have side effects its still probably better than late Alzheimer's I heard its horrible thank god none of my family have gone through it
@thisonetime410
@thisonetime410 3 жыл бұрын
My grandma had Alzheimer’s and it crushed my soul. I always worried I would get it and my kids would feel the same pain. So glad they are making advances.
@swunt10
@swunt10 3 жыл бұрын
give people and their doctor free choice. it's their decision.
@backhandok
@backhandok 3 жыл бұрын
Well, in fairness, the best way to see if medicine works, is to have it in regular use. Of course after safety clinical trials and so on.
@lubricustheslippery5028
@lubricustheslippery5028 3 жыл бұрын
Proper statistics is only possible with randomized trails with controlls. If the effect is huge it's apparent without it if the effect is small real science is needed.
@thetruthstrangerthanfictio954
@thetruthstrangerthanfictio954 3 жыл бұрын
I disagree, because there is a financial incentive. If the drug doesn't work or worse yet is harmful, we will never know because the company that made the drug will cover up evidence to the contrary. Happens all the time.
@naysneedle5707
@naysneedle5707 3 жыл бұрын
As long as it's reasonably safe, a maybe is better than nothing at all.
@Zombieboss2002
@Zombieboss2002 3 жыл бұрын
Neurodegenerative diseases like alzeimers and dementia are heartbreakingly cruel. My grandmother has dementia and seeing first hand how quickly her memories faded and the last time I saw her was only 2 years, I doubt she would even know who I am. She is far beyond any treatment but I look to a day where this plague on humanity is controlled so that I need not fear for the same to happen to my mother.
@lubomirkubasdQw4w9WgXcQ
@lubomirkubasdQw4w9WgXcQ Жыл бұрын
wow your story is rather sad. i have heard that during the last few hours of someone's life that has dementia, they stop showing symptoms and act normally for that time, so i just want you to know that, maybe it will make you feel better.
@trust1301
@trust1301 3 жыл бұрын
U have to make a beginning somewhere sometimes even if it is risky instead of leaving the sufferers with no choice.
@trust1301
@trust1301 3 жыл бұрын
@@Channel24377 common folks are at a vulnerable position to not to control prices. It is the Govts that need to take calls
@lukemullan636
@lukemullan636 3 жыл бұрын
Made me wanna cry when the trial dude was a surgeon not able to do his job
@justdogood7413
@justdogood7413 3 жыл бұрын
Then be an advocate to eco-friendly living and save lives if you really care! It's shocking when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you have doubts on pollution, inhale some exhaust fumes for a few minutes and get back to us [Caution: Do seek medical experts advice before proceeding with this experiment]. Please share!
@zen9571
@zen9571 2 жыл бұрын
Over 20 years ago I worked with an Alzheimer patient involved in the Namenda study. Namenda gave the patient awful diarrhea, made her lethargic and unable to speak or sit up straight. After two years the drug was stopped and she was given low dose Ritalin and coffee three times a day. Her face was no longer "frozen", she once again could smile, talk and feed herself finger foods. She could hold her head up and had normal elimination. I know they spend a lot on research, and developing these drugs. I would use caution before thinking there's a new miracle drug, sometimes the side effects diminish what quality of life they have.
@kittywalker2944
@kittywalker2944 3 жыл бұрын
Perhaps what’s changed is that more of the FDA committee’s family members have been affected ... Watching my father decline and (his) struggle to accept his decline is crushing - as is losing him while he’s still physically healthy. It’s hard to appreciate until it happens to someone in ur life.
@legobrickabrac
@legobrickabrac 3 жыл бұрын
This must be really fruustrating for the victim and family to have this hope so nere but yet so far. In My opinion they should let people take the drug At there own risk, if it turns out they are one one the unlucky ones they would rather of tried then to of faced to worst affects of the desease.
@chaosXP3RT
@chaosXP3RT 3 жыл бұрын
I'm sure the right amount of money found its way into the right people's pockets
@sacasticdata1840
@sacasticdata1840 3 жыл бұрын
Which FDA committee family members have been affected?
@emmalouize
@emmalouize 3 жыл бұрын
It’s a cruel disease. It’s stolen my grandfather away and I wish he would just go to sleep and not wake up instead of having to suffer everyday. He has to wear nappies (diapers) he falls often. He’s not there anymore but his body keeps him alive because he is still young. It’s like a form of torture and I really pray that he doesn’t ever have moments where he is aware of his situation. It’s absolutely heart breaking. He would never have wanted this ever. He would have ended things himself if he knew this was his future. It also takes a huge emotional toll on the family and it does become a burden, which is a horrible and hard thing to admit.
@strategic1710
@strategic1710 3 жыл бұрын
I like the question about what has changed with the science recently and why the accelerated approval. Someone important probably has a loved one with early stage Alzheimer’s.
@kgcotton326
@kgcotton326 3 жыл бұрын
I am very happy that Biogen and Eisai and other companies have been able to co-develop a drug to treat Alzheimer's disease. 🇯🇵🤝🇺🇸
@nelsonderrick2931
@nelsonderrick2931 3 жыл бұрын
Hello 👋 How you doing ?
@wakeandbakewithmaryjane1767
@wakeandbakewithmaryjane1767 3 жыл бұрын
THIS is such great news ! As a senior care worker, its soul breaking to watch the effects over time, the families and patients crying because they know and you are helpless. This is just wonderful !
@julia-du1eg
@julia-du1eg 2 жыл бұрын
I might have alzheimer because i dont remember asking
@maxil8988
@maxil8988 2 жыл бұрын
@@julia-du1eg stealing the joke from a comment on it's just a burning memory trap remix, cringe
@aeulia4359
@aeulia4359 3 жыл бұрын
Beautiful. Hope I grow up into developing new medicine like these people. Very inspirational
@tjvanderwalt92
@tjvanderwalt92 3 жыл бұрын
This is brilliant news. I might need it one day 😅 It seems to work. Hopefully everyone gets on board.
@timedone8502
@timedone8502 3 жыл бұрын
It seems to have very little effect if you ask me. This actually means more drugs will be approved as the FDA has set the bar so low..
@chanchan5349
@chanchan5349 3 жыл бұрын
I nursed my mother with ALZ & it is crushing, but what I've been reading is to begin a Keto diet with IMF & longer fasting to push ones body into autophagy which lets the body heal itself while you're younger. Especially those who have it in families. For me, I have begun changing my diet now, trying to heal my gut, liver, etc. Dr. Perlmutter is a good source of information
@Frivillig
@Frivillig 3 жыл бұрын
This debate is similar to the 90s HIV/AIDS medicines. Patients and families will try everything to have more time with the effected!
@cilbup
@cilbup 3 жыл бұрын
Thank u all. M so much elated to hear this.
@jackaddie7866
@jackaddie7866 3 жыл бұрын
Wow. The differences in amyloid in the scans really took me by surprise. Proof that science always wins.
@thetruthstrangerthanfictio954
@thetruthstrangerthanfictio954 3 жыл бұрын
But not everyone agrees that amyloid causes the disease, and there is evidence that the drug may do more harm than good, such as causing brain bleeds. Yes it reduces amyloid, but if amyloid is just a symptom, then this drug is no different than all the others that just treat symptoms.
@noobplays-saslow2920
@noobplays-saslow2920 3 жыл бұрын
@@thetruthstrangerthanfictio954 Its still not proven that Amyloid isn't the cause of it though, and either way if we believe it can at least help against Alzheimers then why not use it?
@thetruthstrangerthanfictio954
@thetruthstrangerthanfictio954 3 жыл бұрын
@@noobplays-saslow2920 my main problem with it is that if it does not work and only attacks the symptoms, then data to suggest the truth will never come out because the company that developed it will have a financial stake to make sure the truth doesn't come out. I have read a lot about corruption in pharmaceutical companies, and they have been known to cover up things that work, such as Hydroxychloroquine for COVID.
@jackaddie7866
@jackaddie7866 3 жыл бұрын
@@thetruthstrangerthanfictio954 I am not educated in medicine but I understand that point. However, If treating the symptoms improves the persons quality of life then why not use it? Also, is a bleed on the brain not treatable whilst Alzheimers has no current treatment?
@justdogood7413
@justdogood7413 3 жыл бұрын
Then be an advocate to eco-friendly living and save lives if you really care! It's shocking when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you have doubts on pollution, inhale some exhaust fumes for a few minutes and get back to us [Caution: Do seek medical experts advice before proceeding with this experiment]. Please share!
@TheRobbur
@TheRobbur 3 жыл бұрын
50k a year is what this costs. Disgusting.
@aarondingain9006
@aarondingain9006 3 жыл бұрын
If only this was around when my grandad was alive looking after him would not have been so hart breaking
@carbunkle5643
@carbunkle5643 3 жыл бұрын
I'm 64 and getting more forgetful and all that stuff. It's serious now. I would take pretty much anything that would reverse the onset of dementia and alzheimer's.
@user-worldpeaceandlove
@user-worldpeaceandlove 3 жыл бұрын
Eizai(Japanese pharmaceutical company) developed that drug . I'm proud of them .
@Victor-tl4dk
@Victor-tl4dk 3 жыл бұрын
It's a horrible disease. Especially if your loved one is a toxic and seemingly heartless person. With logic and memory torn out all of that starts to show. The whole situation just becomes 10 times worse.
@justdogood7413
@justdogood7413 3 жыл бұрын
It's even more shocking is when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you doubt, inhale some exhaust fumes for a few minutes and get back to us.
@billkeon880
@billkeon880 3 жыл бұрын
The biggest argument against the drug is that even though it does reduce amyloids, they say there’s no proof reducing amyloids will reduce cognitive decline. However, that’s what trials should be for....assess risk and evaluate effectiveness. One thing is CERTAIN.... doing nothing will cause accelerated death and it’s not pretty. My dad went through it and it was horrible
@justdogood7413
@justdogood7413 3 жыл бұрын
It's even more shocking is when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you doubt, inhale some exhaust fumes for a few minutes and get back to us.
@momentumstocks3493
@momentumstocks3493 3 жыл бұрын
@British Chap Craig has Alzhiemers...show some compassion
@XavierAway
@XavierAway 3 жыл бұрын
I don't get why the FDA are so hesitant about approving it, if there's a 1% chance it will improve outcomes for Alzheimer's sufferers it's worth approving is it not?
@767kevin
@767kevin 3 жыл бұрын
Right?! So everyone’s unique maybe it works for some or others; it’s a personal choice if the patient feels it helps them then whose to stand in their way and say no?
@XavierAway
@XavierAway 3 жыл бұрын
@@FratboyOX call me old-fashioned but I think that should be up to the patient as long as the FDA acknowledge the long-term effects are unknown I think that’s good enough if there’s a chance it stops them developing an absolutely horrific illness
@willienelsongonzalez4609
@willienelsongonzalez4609 3 жыл бұрын
I’m glad there’s been some steps forward in targeting the cause of Alzheimer’s, but I wouldn’t want anyone to come to any harm or become ill as a result of the drug. I do hope proper research has been conducted and the drug company hasn’t “fudged” the results. Here’s hoping the evidence holds up to thorough scrutiny!
@itchntohitch4143
@itchntohitch4143 3 жыл бұрын
At $56,000 per year, this will become yet another designer drug for the rich and famous. The rest of us can fade into the sunset......
@TheCaptainSplatter
@TheCaptainSplatter 3 жыл бұрын
Free health care in UK.
@michellewilson7412
@michellewilson7412 3 жыл бұрын
Canadians will be covered. Universal Healthcare must be in every country. USA needs to step up and give healthcare for all.
@andyt3789
@andyt3789 3 жыл бұрын
Yes with a disease such as this, those that need it should have it.
@TheGregcawthorne
@TheGregcawthorne 3 жыл бұрын
At the end of the day if I have the beginning of Alzheimer’s, I'd take this regardless. Maybe not if it causes immense pain, which it seems it doesn't.
@Phenomenal36
@Phenomenal36 3 жыл бұрын
Fortunately ive never experienced first hand Alzheimer’s with family or whatnot, but I can imagine it’s devastating effect. Hopefully the treatment shows some positivity
@justdogood7413
@justdogood7413 3 жыл бұрын
Then be an advocate to eco-friendly living and save lives if you really care! It's shocking when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you have doubts on pollution, inhale some exhaust fumes for a few minutes and get back to us [Caution: Do seek medical experts advice before proceeding with this experiment]. Please share!
@marinamccleery2683
@marinamccleery2683 3 жыл бұрын
It’s great to see good positive headlines!
@justdogood7413
@justdogood7413 3 жыл бұрын
It's even more shocking is when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you doubt, inhale some exhaust fumes for a few minutes and get back to us.
@momentumstocks3493
@momentumstocks3493 3 жыл бұрын
@@justdogood7413 $$$...it is all about $$$ and nothing else
@HalfEatenMushroom
@HalfEatenMushroom 3 жыл бұрын
Its quite interesting that the major determinant of debate around this drug is the various theoreticians who either buy the Tau or AB theory of Alzheimer's. Likely they aren't mutually exclusive, but some top researchers treat them as so.
@shashipancholi
@shashipancholi 3 жыл бұрын
The significance here is that current treatments can only slow the progression of the disease (eg memantine) however this sounds like it can restore cognitive function
@dollywasher
@dollywasher 2 жыл бұрын
Very encouraging
@MrBuddy-r8w
@MrBuddy-r8w 3 жыл бұрын
Please don't let big "Pharma" quash this treatment. I watched my grandma go through and die from Alzheimer's. This is Amazing news!!
@thetruthstrangerthanfictio954
@thetruthstrangerthanfictio954 3 жыл бұрын
I have been following the story of this drug. It is big pharma that came out with it. It doesn't cure it, and it is questionable if it actually does anything at all. Big pharma will make big money because people will take this drug for the rest of their lives.
@SI-ln6tc
@SI-ln6tc 3 жыл бұрын
@@thetruthstrangerthanfictio954 Not necessarily. Cure for polio. Cure for hepatitis now. Vaccine for HPV (instead of long treatments). Drugs like Ivermectin has completely cured a number of diseases in Africa. As for Big Pharma in this case it was a cooperation between American and Japanese scientists. Which normally would be competing with each other. Does the amyloid MRI brain scans lie?
@thetruthstrangerthanfictio954
@thetruthstrangerthanfictio954 3 жыл бұрын
@@SI-ln6tc actually, from what I have read, the two companies are huge donors to the Alzheimer's Association, and the Alzheimer's Association is one of the reasons the drug got approved (they "begged" the FDA to do it on behalf of patients without disclosing the money from Biogen and the other company). The Alzheimer's association deleted a rough draft from scientists suggesting that the drug didn't work. Something seems fishy to me.
@danielwhyatt3278
@danielwhyatt3278 3 жыл бұрын
This is absolutely terrific news. So glad that the new piece of pioneering medicine has finally actually been approved. It may not be 100% effective, but any treatment is better than none, and those who say otherwise they’re just standing in the way of people actually having a better quality of life. It’s been way too long in the making but now people can at least start to benefit, even if it is for some only in small ways, in getting their lives back.
@mrsanchez256
@mrsanchez256 Жыл бұрын
I hope it gets approved and studied more. Watching my father pass away slowly because of this disease has crushed my soul and broken the hearts of my entire family.
@googleuser4177
@googleuser4177 Жыл бұрын
How many years he spend after diagnosis?
@matthewcox1948
@matthewcox1948 3 жыл бұрын
Some how I don't think this is safe to us for now Because of the economic crisis and the rate of unemployment now is the best time to invest and make money 💯
@prestonblackburn2701
@prestonblackburn2701 3 жыл бұрын
Exactly....nice words
@team-stockmarketcommando2035
@team-stockmarketcommando2035 3 жыл бұрын
@Eddie Bentley Crypto is the future 🚀
@jullinjohn1351
@jullinjohn1351 3 жыл бұрын
@@team-stockmarketcommando2035 Buy gold and crypto
@gulliblejolly5877
@gulliblejolly5877 3 жыл бұрын
I wanted to trade crypto but got confused by the fluctuations in price
@gomesboston9059
@gomesboston9059 3 жыл бұрын
@@gulliblejolly5877 That won't bother you if you trade with a Professional like Mr Ronald Dickson
@Liuhuayue
@Liuhuayue 3 жыл бұрын
Maybe they just need to put them on the highest doses to see any efficacy. It's better than just allowing them to waste away, it seems.
@cris001kay
@cris001kay 3 жыл бұрын
We've seen this time and again with other drugs, where approval is rushed through, and then potentially millions of people are harmed at the cost of billions - Rofecoxib, for example. Aducanumab hasn't been proven to be both safe and effective, but I don't think that's important for the manufacturer, which is ultimately interested in its bottom line and shareholder dividends.
@darjatargetedwoman-straigh8364
@darjatargetedwoman-straigh8364 3 жыл бұрын
In consideration: whatever is "approved" today, it doesn't mean it's good. Mostly it's not, at least not for me. They're playing games with us on a daily basis.
@nata357
@nata357 3 жыл бұрын
If the accumulated amyloid protein can be reduced, it is possible to treat dementia as well as suppress its progression. This is a very desirable drug. I hope that the drug will be approved quickly in Japan, where the aging of the population is a problem, and that research will proceed.
@waynechurch9158
@waynechurch9158 3 жыл бұрын
Please let this work so many people suffering all around the world horrible to see a loved one go throu this
@justdogood7413
@justdogood7413 3 жыл бұрын
Only effective in the early stages of the onset
@justdogood7413
@justdogood7413 3 жыл бұрын
Be an advocate to eco-friendly living and save lives if you really care! It's shocking when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you have doubts on pollution, inhale some exhaust fumes for a few minutes and get back to us [Caution: Do seek medical experts advice before proceeding with this experiment]. Please share!
@thetruthstrangerthanfictio954
@thetruthstrangerthanfictio954 3 жыл бұрын
I wish it did work but I am very skeptical. The original pilot study showed that it didn't work, and likely did more harm than good. It wasn't new data that lead to the approval of the drug, but simply a "re-interpretation" of it. The company that developed the drug did invest lots of money in that type of research. If you ask me, it is more to help big pharma than patients. Also, there is new evidence since 2018 that Alzheimer's is caused by bacteria and not by amyloid.
@LordSolidusI
@LordSolidusI 3 жыл бұрын
Approved for people with Alzheimers, by people with Alzheimers.
@V01DIORE
@V01DIORE 3 жыл бұрын
Calling the drug “this product” kinda sounds like he has pockets elsewhere.
@ab-ll7dv
@ab-ll7dv 3 жыл бұрын
Yeah and he looks like a dirty lawyer too
@cameronf3343
@cameronf3343 3 жыл бұрын
I’ll say that at 21.5 and a family history on both sides of Alzheimer’s, I’m glad stuff’s probably going to be better by my 80s.
@Channel24377
@Channel24377 3 жыл бұрын
True but anyone can get it by their 50s I used to think only old people got it but many get it super young let’s hope things improve by then also I encourage you to find this organizations researching for alz and fund them after doing your research.
@TheCaptainSplatter
@TheCaptainSplatter 3 жыл бұрын
@@Channel24377 I got about 20 years before I hit my 50s.
@Channel24377
@Channel24377 3 жыл бұрын
@@TheCaptainSplatter lol ok what about it I got like 30 years before I hit my 50s doesn’t mean their will be a cure by then although I hope so.
@nomoremrniceguy8106
@nomoremrniceguy8106 3 жыл бұрын
A special treat for Boe Jiden.
@rudyyu5279
@rudyyu5279 3 жыл бұрын
How effective is it against dementia? AZ and dementia are similar but not alike.
@manuelrojas6912
@manuelrojas6912 3 жыл бұрын
"At that time I said fuk that" 😆 🤣 😂
@guy1177
@guy1177 3 жыл бұрын
Hope this won't be a thing we will never hear of again
@legobrickabrac
@legobrickabrac 3 жыл бұрын
This must be really fruustrating for the victim and family to have this hope so nere but yet so far. In My opinion they should let people take the drug At there own risk, if it turns out they are one one the unlucky ones they would rather of tried then to of faced to worst affects of the desease.
@peace4myheart
@peace4myheart 3 жыл бұрын
Driven more by money than by efficacy it seems.
@sethp45001
@sethp45001 3 жыл бұрын
Use speakerphone instead of putting phone up to your head!!!
@loshneenaidoo8537
@loshneenaidoo8537 3 жыл бұрын
I wil be so happy because this treatment wil help many patients
@igor-yp1xv
@igor-yp1xv 3 жыл бұрын
There's a mismatch between the title and the actual video
@mykofreder1682
@mykofreder1682 3 жыл бұрын
It doesn't hurt, other than money, to get it to a lot of people and get data on thousands. You look at statistical length of life and cause of death before and after and you will get a better answer.
@karwinchau4684
@karwinchau4684 3 жыл бұрын
About dam time... better than nothing 💯🙏🏾
@hassansyed5661
@hassansyed5661 3 жыл бұрын
I have seen Vitamin-B is a bit helpful against Alzheimer . My mother is having tremor or shaking of the right hand which is symptom of it. When she regularly use vitamin-B in her diet and through suppliments, I have observed a significant drop-down in hand shaking symptom. Whenever there is a pause or reduction in vitamin-B the problem increases again.
@onenation8707
@onenation8707 3 жыл бұрын
Well done on this it’s an improvement 👏 👏 👏
@HayderAbdulilahAbdulrahman
@HayderAbdulilahAbdulrahman 3 жыл бұрын
IV shots of the medication needs to be given to the patient every four weeks. The coast of each shot is US$ 4k . For one year the coast is US$ 56K. Add to that the coasts of PET scans and MRI studies.
@public.public
@public.public 3 жыл бұрын
so ban the use of pesticides. Get to a root cause of all serious disease. i.e. prevention.
@Pinoy_Central_Official_Backup
@Pinoy_Central_Official_Backup 3 жыл бұрын
This is a huge win for humanity!
@MrShuttz
@MrShuttz 3 жыл бұрын
Why would you advise against it?
@jercan7716
@jercan7716 3 жыл бұрын
I wander how much it will cost around 70k ? Maybe ?
@suskechidori
@suskechidori 3 жыл бұрын
I’ve seen enough of the “judgement” game to honestly believe what’s being put on here rn 🤔, miss me with that 😂😉
@waitisendlesd2163
@waitisendlesd2163 3 жыл бұрын
Stay blessed medical team
@kumeraaderessa5917
@kumeraaderessa5917 3 жыл бұрын
With lots of love and respect/ ETEYE/
@kumeraaderessa5917
@kumeraaderessa5917 3 жыл бұрын
You are always in my heart ❤️ & mind ❤️❤️❤️❤️❤️
@IKNFLY666
@IKNFLY666 3 жыл бұрын
Alzheimer is a horrible disease, my grandpa died of late stage in 2017, not only his brain shrunk in size, the only functioning organs before he died was just the heart and lungs. He needed tubes insert all over him just to ingest and excrete, there’s no way for anyone to live like this.
@asiftahir
@asiftahir 6 ай бұрын
I searched Ginko Biloba and this video came up, does it mean this medicine includes this herb?
@venlafaxinedomperidone8377
@venlafaxinedomperidone8377 3 жыл бұрын
And NHS would beg the US for it
@ItsOnlyBlaze1
@ItsOnlyBlaze1 3 жыл бұрын
every Zombie apocalypse movie is based around scientist trying out Alzheimers Drugs
@SeeLasSee
@SeeLasSee 3 жыл бұрын
There have been SO MANY failed attempts at Alzheimer’s drugs. Some financial analysts will subtract the value of such Alzheimer’s drugs from stock prices of drug companies. Why? Simply because it seems better to afford failure.
@mohammedkamran5407
@mohammedkamran5407 3 жыл бұрын
Anyone know how fast the COVID vaccine was approved or was it?!!!
@peterpanino2436
@peterpanino2436 3 жыл бұрын
The best treatment against Alzheimer's disease: Stop watching television, especially BBC.
@parwanaferozy7914
@parwanaferozy7914 3 жыл бұрын
Right!
@jamaicacruzado4219
@jamaicacruzado4219 3 жыл бұрын
They don't allow it because big pharma companies will have a big loss on those oral meds which also have side effects. Same as using CBD to cure cancer and other debilitating diseases. 😞
@kimberlyperrotis8962
@kimberlyperrotis8962 3 жыл бұрын
Wonderful.
@justdogood7413
@justdogood7413 3 жыл бұрын
Sweet Kimberly, then be an advocate to eco-friendly living and save lives if you really care! It's shocking when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you have doubts on pollution, inhale some exhaust fumes for a few minutes and get back to us [Caution: Do seek medical experts advice before proceeding with this experiment]. Please share!
@vornamenachname1069
@vornamenachname1069 3 жыл бұрын
The problem is that removing those amaloid plaques is not preventing the neurodegeneration. Or in other words: this could be like all other Alzheimer's medicine: it might only slow down the progression of the disease or help momentarily, but the true cause (or causes) of Alzheimers are still far from beeing understood. But it could be that this stuff also has some other properties that do cure the real cause of the disease and thus help anyway. Well, I am glad that it got approved as for the patients suffering from Alzheimer's disease, it's better to try than doing nothing. There are various links that promote the theory of Alzheimer's beeing an autoimmune disease. Just like with some other autoimmune conditions, sometimes to treat the disease, it is enough to mitigate a certain immune response (here: the formation of antimicrobial amloid plaques). But it's more of a treatment than a healing. But autoimmunity and chronic inflamatory conditions are the pink elephant in the room no one likes to talk about because of how bad our understanding of them is. But I am sure that with things like next-generation sequenzing, microbiome research and artificial intelligence data analyzing, a lot will become clear in the next decade.
@tyler7937
@tyler7937 3 жыл бұрын
The side effects don’t outweigh the potential. If it causes cancer that’s ok as it usually takes 30 years to form from medication. This will seriously extend the quality, and quantity of life of millions of people
@linettelow
@linettelow 3 жыл бұрын
I agree with Dr Maria that people should have the right to access this treatment while there is still time, and they meet these criteria. If it is safe to administer and more importantly efficacious in targeting the root cause of AD, we should support the cause and not deny the opportunity of better health and improved quality of life to those in need. 💙
@faebalina7786
@faebalina7786 Жыл бұрын
What's confusing is how can people who don't have amyloid plaques in their scans still be said to have Alzheimer's dementia if that's seen as the key biomarker.If in fact it isn't amyloid then how would the limited but clearly real success of this treatment be explained as it works by reducing the plaques.
@theancientsancients1769
@theancientsancients1769 3 жыл бұрын
Alzheimer's is not caused by amyloid, that's is just an affect and is dismissed in large. Tau protein plays a more important role not in just Alzheimer's but other neuro disease like Parkinson's too
@thetruthstrangerthanfictio954
@thetruthstrangerthanfictio954 3 жыл бұрын
Actually, its not either protein. They are both part of the immune system, and are symptoms of the disease. The actual cause of the disease is an infection. This is just a victory for Big Pharma.
@sounsure9108
@sounsure9108 3 жыл бұрын
But the build up of amyloid cause the dementia and memory loss seems worth it to me my mom forgets who I am by the end of a 5 minute phone call and lives 3000 km away
@momentumstocks3493
@momentumstocks3493 3 жыл бұрын
Yes it is not a cure but a therapy....it does help but doe snot prevent or cure...understand?
@TheAsentra
@TheAsentra 7 ай бұрын
I can guarantee you that if that guy who’s against approving it was suddenly diagnosed with Alzheimers, he would be the first one reaching for it. It runs in my family and seeing it first hand I would rather die than have it.
@alimuhammad2358
@alimuhammad2358 2 жыл бұрын
My father suffer from this deases. What to do??
@Oblivion889
@Oblivion889 3 жыл бұрын
It has been 20 years since covid ? Was I in coma ? Just kidding.
@simplicitas5113
@simplicitas5113 3 жыл бұрын
I would have liked a counter argument based on... Anything. Side effects maybe? Idk why the committee is against it if pilot data is good
@justdogood7413
@justdogood7413 3 жыл бұрын
Then be an advocate to eco-friendly living and save lives if you really care! It's shocking when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you have doubts on pollution, inhale some exhaust fumes for a few minutes and get back to us [Caution: Do seek medical experts advice before proceeding with this experiment]. Please share!
@thetruthstrangerthanfictio954
@thetruthstrangerthanfictio954 3 жыл бұрын
That's just it, the original pilot data wasn't good, and there is no new data, just a "reinterpretation" of it. The company that developed the drug invested lots of money in that type of research over the years, so if you ask me, it has big pharma written all over it.
@paulgillespie9855
@paulgillespie9855 3 жыл бұрын
How do you spell it ?
@lancetan2263
@lancetan2263 3 жыл бұрын
This is currently the last ditch effort available for anyone that have the disease, people that are dying a slow, painful (physical, mental, & emotional) death, families that have to witness the whole process, watching their loves one slowly drifting way. As long there is no serious side effect that make people even more sick/die quicker, let people use it. Any success case is a win for humanity. Government only need to make sure it's priced reasonably so no party can take advantage profiting excessively.
@Greenpoloboy3
@Greenpoloboy3 3 жыл бұрын
Approve it here FAST
@justdogood7413
@justdogood7413 3 жыл бұрын
Then be an advocate to eco-friendly living and save lives if you really care! It's shocking when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you have doubts on pollution, inhale some exhaust fumes for a few minutes and get back to us [Caution: Do seek medical experts advice before proceeding with this experiment]. Please share!
@gsynth1731
@gsynth1731 3 жыл бұрын
This is a big step forward.
@justdogood7413
@justdogood7413 3 жыл бұрын
Then be an advocate to eco-friendly living and save lives if you really care! It's shocking when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you have doubts on pollution, inhale some exhaust fumes for a few minutes and get back to us [Caution: Do seek medical experts advice before proceeding with this experiment]. Please share!
@mrcool599
@mrcool599 3 жыл бұрын
This antibody treatment will cost 45k per year. Well, shit when the government will not pay for you.
@justdogood7413
@justdogood7413 3 жыл бұрын
It's even more shocking is when governments by permitting cigarettes, are knowingly endangering our lives through 2nd & 3rd-hand smoking as well as fossil fuel emissions. Breathing toxic air is akin to drinking sewage water! Even more people die daily as a result of pollution. Where's the outrage? Where's my right to clean air? If you doubt, inhale some exhaust fumes for a few minutes and get back to us.
@parwanaferozy7914
@parwanaferozy7914 3 жыл бұрын
Excellent!
@saddabsuhel2758
@saddabsuhel2758 3 жыл бұрын
Great job
@christianang1293
@christianang1293 3 жыл бұрын
I hope it can do what its promise and improve the drug more.
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