The mouse, as a smaller animal, has a higher metabolism. This higher metabolism may increase senescence, and improper senescence increases inflammation if the script drops off. We know that senescence and cell division-imperfect in some cases - play a role in creating cancer in the body (mice have a higher risk for cancer than elephants).

The cart wouldn't have fallen apart if it was regularly checked and regularly maintained. I am all in with Bryan Johnson.

If diabetes is considered a disease of aging, then investigate why it is experienced by people of all ages.