TWiV 1130: Clinical update with Dr. Daniel Griffin

Рет қаралды 7,121

Күн бұрын

In his weekly clinical update, Dr. Griffin discusses H5N1 influenza in the bird and cow communities of Colorado and Michigan and dengue in New York and the US before reviewing the recent statistics on SARS-CoV-2 infection, the absence of association with proton pump inhibitors and COVID-19 severity in children, where to find PEMGARDA, the effectiveness of molnupiravir and dexamethasone, convalescent plasma, what to do when healthcare workers succumb to SARS-CoV-2 infection, a resource of long COVID answers, how the WHO and CDC define long COVID and how it compares to ME/CSF.
Show notes at www.microbe.tv/twiv/twiv-1130/
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Пікірлер: 56

@lesfaby8997 26 күн бұрын

_KZfaq timestamps by Les_ 00:37 Bow Tie Fecal Pathogens 02:30 Quotation (E. Hemingway) 03:17 H5N1 influenza in the bird and cow communities of Colorado and Michigan 04:25 dengue in New York and the US 06:58 *CoViD* 05:52 Global warning helps disease vectors reviewing the recent statistics on SARS-CoV-2 infection 08:53 the absence of association with proton pump inhibitors and COVID-19 severity in children 11:10 where to find PEMGARDA 11:21 Early Viral phase the effectiveness of molnupiravir and dexamethasone convalescent plasma 11:57 Early inflammatory phase 12:12 Long CoViD what to do when healthcare workers succumb to SARS-CoV-2 infection 12:20 a resource of long COVID answers 18:00 Possible mechanisms driving long CoViD how the WHO and CDC define long COVID and how it compares to ME/CSF. 30:38 How to donate 31:05 *Your Qs answered by Dr D* see microbe.tv/twiv/twiv-1130-letters/ 31:11 Leah 32:27 Julie 34:25 Ian 38:48 Anonymous _Audio podcast timestamps by Jolene_

@tomkunich9401 25 күн бұрын

Other than the natural and rather slow change of the climate, which is cyclical, there is no climate change. If you pretend that there is, you are being led about by the nose.

@kerrycampbell3924 24 күн бұрын

Thanks for the timestamps.

@dacisky 25 күн бұрын

I had no idea there was so much about long covid,great episode!

@rbdesigner725 25 күн бұрын

My long haul started Dec 2020 no gap between acute and long Covid. It just morphed. Horrible year 1, bad year 2, management since. Quit work for 2 years, managing now. Thanks for keeping the word going.

@katiehettinger7857 24 күн бұрын

I also developed Long Covid early on, after contracting the wild strain of Covid -19 in February 2020. I felt lucky to survive the first year. My heathcare org. didn't recognize Long Covid until April 2020. They have a clinic that is useless, but other departments have been helpful. I've kept up following the science and been willing to try therapies that relate to my ongoing symptoms. I hope you are recovering. ❤

@rbdesigner725 18 күн бұрын

@@katiehettinger7857 Thanks Katie it’s been a rough ride. Keep up the good work. All the best.

@WillNewcomb 26 күн бұрын

Huge thank you. Great to hear about that body promoting evidence based understanding of Long Covid. And great to get a clear explanation of times of infectivity. I've copied the transcript for future reference.

@DudeFun-yi7nu 25 күн бұрын

great long covid info, thank you

@terrydoyle1141 25 күн бұрын

Exactly right! I look forward to more but what a daunting task after looking at the lists presented by Daniel. Such a complex disease to start with with its phases and symptoms and then more of that complexity in long COVID mechanisms and treatments.

@crohillhouse 21 күн бұрын

This is such exciting information on what is being done to address PASC. I am sharing this episode as much as possible!

@moniqueheubel8970 25 күн бұрын

Done worry if you repeat a quote- they deem repeating. What a creative and fun way to start a show that is so important to our well being!

@JimsPub-ds3qs 25 күн бұрын

Thank you.

@Rene-uz3eb 25 күн бұрын

Low serotonin in long covid: this again points to covid caused gastrointestinal damage preventing vitamin B12 absorption, since b12 is needed in synthesis of serotonin. Lack of b12 could also somewhat explain change in gut microbiome. Also anemia seems to be frequent in long covid.

@HeatherOrdover-CraftLit 25 күн бұрын

8:23 is it possible that the Winter Peak and Summer Surge are driven by the increased amount of people indoors to escape extreme cold/heat? I know you mentioned that not nearly enough of the funds to improve HVAC filtration were used to purpose. 🤷‍♀️ if COVID isn’t seasonal -the way the flu is-then could peak/surge be caused by a ‘tipping point’ of % of time a higher % of bodies spend in enclosed spaces?

@robinirons541 25 күн бұрын

Are any respiratory viruses seasonal? I’ve had colds in spring and summer months long before Covid reared its ugly head. I blamed my kids at the time as being the lurg spreaders as their immune systems had not met any of usual suspect viruses until they started school. Stay safe😊

@christopherrobinson7541 25 күн бұрын

@HeatherOrdover-CraftLit I agree the key factor is the degree of close contact and that depends on people's behaviour. The US is a large country and has different climates, that tend to blur the picture. The UK is smaller and the pattern is much clearer. There are two peaks, one in late Summer/early Autumn and another early in January.

@TinaLee 22 күн бұрын

Yes, Yes. It's so good to see my own thoughts written by someone else. Summer increases could also be caused by the large number of people who travel in summer, similar to holiday surges after each family gathering, but less concentrated in time. One person arriving home from a vacation in Puerto Rico could spark an uptick in several communities (not just their own) if they are shedding virus while traveling.

@TinaLee 22 күн бұрын

I only meant to add another cause on top of the indoor transmission due to heat and AC, not to discount your thoughts. I agree with you as to the biggest cause of summer uptick. And that "tipping point" is crucial to understanding how surges work.

@christopherrobinson7541 21 күн бұрын

@@robinirons541 Both RSV and the Flu are seasonal.

@srr9281 25 күн бұрын

At 11:10 in the “Link” where to get Pemgarda, the link merely takes you to an old link that is basically an old press release by the FDA. No actual contact information is provided! As this is the second time this has happened I thought I would let you folks know. Vincent and Daniel still love you guys though. ❤

@stormwalker321 20 күн бұрын

Excellent program, thanks Vincent and Daniel

@trixiegirl9401 25 күн бұрын

Great show! Thank you.

@towsifhossain2010 24 күн бұрын

Great listen from the doctors.

@alijawad2042 25 күн бұрын

Thank you very much

@donnah9089 24 күн бұрын

Thanks for the overview Of long Covid. Very helpful

@TatianaBoshenka 24 күн бұрын

Fantastic information. Thanks!

@SB1975P 25 күн бұрын

Would like to hear more on NAC

@sueyoung2115 19 күн бұрын

NAC is a sulfur- like supplement. I used it with bromelain, ( pineapple enzyme) it was supposed to break down the spike. A couple of weeks use did seem to help.

@traianliviudanciu8665 8 күн бұрын

Theoretically,NAC decrease blood viscousity

@Idahomie 25 күн бұрын

long covid, did he mention 'grinding of the teeth'? bruxism?

@riok6234 25 күн бұрын

What period in the history of the earth did the climate of earth not change? I'm not denying change is happening.. just acknowledging change has been and will continue to happen.

@robinirons541 25 күн бұрын

The climate has always changed and long before man started having a fire to keep warm.

@katiehettinger7857 24 күн бұрын

True, but the rate of change is unprecedented. Look up all other periods of changes. Even those marked as fast are nothing compared to the rising temperatures we are facing today. Consider the fact in a short time, the plant will not support the present human population.

@tomsteinberg8106 22 күн бұрын

Extremely rapid anthropogenic global warming, overwhelming evidence, virulently denied by reactionary elements & fossil fuel interests -- now the argument is a rather lame, well, the climate always changes, still denial, still missing the point

@petervanderwaart1138 25 күн бұрын

I discussed Pemgarda with my oncologist yesterday. Our hospital is not yet set up for it. She said it is not yet known how long the immunity will last. We are thinking of getting in November to have the protection during the winter peak.

@katherinecroll 23 күн бұрын

If you were to get it now, you would be eligible again in November (every 90 days). If you are at higher risk or immunocompromised, it certainly couldn't hurt as we are tending to see summer surges still!