What are BETA BLOCKERS? How do they work? | Bisoprolol, Atenolol, Carvedilol, Metoprolol

Рет қаралды 8,853

Күн бұрын

How do beta blockers work and what do they do to your body? Well, this video is for you! Here's the explainer with the what, how, why, side effects, history and pharmacology (two advanced sections in the 2nd half).
There are lots of beta-blockers out there and they're really good for heart conditions and high blood pressure. They can also be used for glaucoma.
Common ones include bisoprolol, atenolol, labetalol, carvedilol, metoprolol, propranolol, sotalol. You might also know them by their brand names: Tenormin, Cardicor, Emcor, Betaloc, Lopressor, Nebilet, Angilol and Inderal.
As always we go through things in simple terms and then for the hardcore nerds we're into the complex stuff.
You'll learn about how these drugs act on the beta adrenoreceptors in your body - that's where adrenaline, noradrenaline (or epinephrine and norepinephrine) bind.
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#betablockers #medicine #drugs #empowerment
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CHAPTERS:
00:00 - What is a Beta Blocker?
01:05 - Why take it?
01:45 - How does it work?
03:50 - Side effects
04:56 - The history of beta blockers
09:31 - Pharmacology
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Light reading to find out more...
Whalen, Karen., Rajan. Radhakrishnan, and Carinda. Feild. Pharmacology / Karen Whalen ; Collaborating Editors, Rajan Radhakrishnan, Carinda Feild. 7th ed. Philadelphia: Woltrs Kluwer, 2015. Print.
Page, Catrin et al. Pharmacology / Catrin Page ; Series Editors, Philip Xiu, Shreelata Datta ; Faculty Advisor, Clive Page. Ed. Philip Xiu, Shreelata Datta, and C. P. Page. 5th edition. Edinburgh: Elsevier, 2019. Print.
Waller, Derek., and Derek. Waller. Medical Pharmacology & Therapeutics / Derek G. Waller ... [et Al.]. 4th ed. Edinburgh: Saunders/Elsevier, 2014. Print.
Baker JG, Hill SJ, Summers RJ. Evolution of β-blockers: from anti-anginal drugs to ligand-directed signalling. Trends Pharmacol Sci. 2011 Apr;32(4):227-34. doi: 10.1016/j.tips.2011.02.010. Epub 2011 Mar 21. PMID: 21429598; PMCID: PMC3081074.
Srinivasan AV. Propranolol: A 50-Year Historical Perspective. Ann Indian Acad Neurol. 2019 Jan-Mar;22(1):21-26. doi: 10.4103/aian.AIAN_201_18. PMID: 30692755; PMCID: PMC6327687.
Frishman, W.H. (2007), A Historical Perspective on the Development of β-Adrenergic Blockers. The Journal of Clinical Hypertension, 9: 19-27. doi.org/10.1111/j.1524-6175.2....
Information on this video is up to date as of June 2023.
If you have any questions or clarifications please contact me through the Stealth Doctor channels in the About section.

Пікірлер: 32

@ncediledlamini4667 10 күн бұрын

I came here clueless. You just explained this in a more simpler way . Thank you

@harryandnatalia Жыл бұрын

Another really useful video. I get asked these questions every day from patients, and explaining in a simplified way is so much easier 😊

@TheStealthDoctor Жыл бұрын

Thanks again Harry! Glad it's useful!!

@harryandnatalia Жыл бұрын

@Stealth Health all your videos are so helpful and very well put together. Looking forward to more content 😁👍🏻

@mehreenkaur1162 5 ай бұрын

Exactly, thanks @Stealth Health for such a great content and explanation. Looking forward to more videos :)

@paulinegrant1067 Жыл бұрын

Very informative. And also fun!

@geordiebedlington587 Жыл бұрын

Truly, another most excellent piece of work. It makes it very easy to understand!

@divinelightms 3 ай бұрын

Excellent video!!! Thank you. ❤

@g7eit 4 ай бұрын

I’ve been on beta blockers for 11 years and I’ve been wondering why I never get the fight or flight thing. I just thought my brain was wonky but this explains it. Thank you

@TheStealthDoctor 4 ай бұрын

You're welcome!!

@nenadcubric2663 Ай бұрын

Which 1 you take??

@g7eit Ай бұрын

@@nenadcubric2663 bisoprolol plus a bunch of others. Not exactly sure what they do

@robingrant832 Жыл бұрын

An excellent video!!

@alanalaa1381 3 ай бұрын

Nice.I like this information. Thanks

@Slagstripes Ай бұрын

Me and everyone I know personally who's on bisoprolol have all started with tinnitus

@IAmDaniSoares Жыл бұрын

Thank you, getting closer to understanding this 😂 Please keep doing videos 🎉

@TheStealthDoctor Жыл бұрын

Will do!

@gracekeartland-hough1049 Жыл бұрын

So cool!

@TheStealthDoctor Жыл бұрын

Thanks so much!

@toddmoore9138 Ай бұрын

I was on a large dose of Beta Blockers for 2 months, and I couldn't take it. I had to get off of them. I tapered in half and then in half again over the last month, and when I finally stopped them, I had 2 weeks of feeling like I was having a heart-attack. It was terrible. I hope they help some people, but the way I felt while taking them didn't work for me......

@brendaayuma3489 3 күн бұрын

So when you finally stopped them were you okay?

@mariarytchenko679 Ай бұрын

🔥

@christineellengalbraith2215 4 ай бұрын

So can a beta blocker for b1 receptors trigger high potassium levels?

@nenadcubric2663 Ай бұрын

I feel calm and good on Propranolol or Atenolol but bad on Bisoprolol??

@masala09 Ай бұрын

I’ve been put on beta blockers, fine so far in dealing with the palpitations after the Covid jabs but finding they give me very loose bowels.

@BlaxJakx 9 ай бұрын

Have been in hospital for my crohns and colitis the past 8 weeks and my blood pressure along with heart rate over the past few months has been getting worse and worse and I’ve just been put on this drug today due to the results of the past 3 days of ECG results. I’m only 31 (literally turned 31 last week). I’m not overweight and it’s come as a bit of a shock as like when you get anything wrong with your heart you assume it’s really really bad? My parents and family are visiting tomorrow and I know they will be asking what’s what and I don’t know if I want to tell them as they will worry and I don’t want them worrying.

@TheStealthDoctor 9 ай бұрын

Sorry to hear this. Look, high blood pressure can cause your heart to be irregular, so treating with beta blockers can both improve your blood pressure and calm fast heart rates. A lot of people have this issue so you needn't be worried as long as your doctor is looking after you, you carry on learning about your condition and stick with the plan. At your age it sounds like there's a genetic component to all this. Hope this helps, I'm afraid I don't give any personalised advice here, but it might make sense to ask your doctor to explain things in a bit more detail for you. Take care!

@BlaxJakx 9 ай бұрын

@@TheStealthDoctor do you have a email we could have conversation via, unbiased opinion would be amazing.

@BlaxJakx 9 ай бұрын

@@TheStealthDoctor yes very true in regards to genetic. I found out last night in conversation with my fathers side of the family that my dad, his grandad and their brother and sister all had heart related issues or had to have by passes before the age of 35 and 42 years old. I’m still in hospital in Salisbury uk at the moment waiting for a new immune suppressant therapy (biologics) which I’m having on Monday and then hopefully I will be allowed to go home. Then come back a week later for a colonoscopy to look at a new area of damage further up from a previous terminal illium resection I had 6 years ago but now it is spreading outward on that join and large bowel is very inflamed but I am hoping the new biologic therapy treatment will be better than the last 2 which have failed and then that in turn could have a positive effect on stress, heart and blood pressure. I have asked the nurse in charge this evening for more info into why and what the ECG really showed and why and how long I am on the beta blocker for but I was told I would need to have a conversation with my gp or that sort of person tomorrow morning when they do the rounds on the ward I’m on. Sorry for the long rant, any advice is obviously taken lightly and I just want an unbiased opinion which then I can relay the information tomorrow to whoever I speak to just so I atleast know a bit more before I have to sit and listen trying to take it in from then tomorrow in a quick 2 min chat as they have a very busy hospital here in Salisbury so you get very little 1:1 time with the docs/specialists.

@BlaxJakx 9 ай бұрын

@@TheStealthDoctor at its worst the past week it’s been 168 over 107 but 24 hrs on the beta blocker and it’s gone to 154 over 102 and then this evening it was 141 over 98. So it is slowly working I assume?