What are SGLT2 inhibitors and how do they affect kidney disease?

  Рет қаралды 10,135

Plant Based Kidney Health

Plant Based Kidney Health

Жыл бұрын

⚡️Connect with us on Social Media:
Sean Hashmi, MD, MS, FASN
www.selfelements.com
www.SELFPrinciple.org
www.instragram.com/seanhashmimd
Michele Crosmer, RD CSR
plantbasedkidneys.com/
/ plantbased.kidneys
Disclaimer
The information provided on this channel is for educational purposes only, and does not substitute for professional medical advice. Please consult a medical professional or healthcare provider for medical advice, diagnoses, or treatment.

Пікірлер: 39
@ricka.6758
@ricka.6758 Жыл бұрын
Thanks for the advice regarding SGL2 Inhibitors. For a future broadcast can you discuss the drug called Spironolactone and when it should be prescribed and if it has any benefits for kidney patients? Much appreciated.
@ddutton4716
@ddutton4716 Жыл бұрын
Ricka, He very briefly discusses this drug at 14:16 in kzfaq.info/get/bejne/f9Onl8RyuLGXk4k.html . Dr. Hashmi, Please explain the advantages of the new selective nonsteroidal MRAs over the older class including less potassium retention, benefits to other organs and less side effects. Thanks for this video. The FDA recently approved the new selective NSMRA finerenone but it is expensive. Literature is sparse on its use in nonalbuminuria or nondiabetic individuals however and it is not labelled for these individuals.
@JoseChavez-fe2zb
@JoseChavez-fe2zb Жыл бұрын
Great information as always . Please keep doing it
@zonrey2781
@zonrey2781 Жыл бұрын
I don’t have a nephrologist. My endocrinologist prescribed Jardiance for my DM 2 and Stage 3 CKD, 55 GFR and microalbumin/creatinine,urine 858 up from 279. Hoping going on plant based kidney health diet & Jardiance since September 2022 will help lower albumin in urine.
@Health-And-Diabetes
@Health-And-Diabetes Жыл бұрын
Thanks Dr. I have been on jiyadiance for around 4 years.
@richt6353
@richt6353 Жыл бұрын
Thank You!
@HeyYall398
@HeyYall398 Жыл бұрын
I would be grateful if you could also create a video on the topic of Finerenone and its impact on kidney health for DKD (non-steroidal Mineralocorticoid Receptor Antagonist (MRA)).
@jorgeconj
@jorgeconj Жыл бұрын
I have been prescribed Farxiga by my nephrologist and even got a free botle with a cupon but Im not using it. Im not a diabetic or have proteinuria. Creatinin is about 1.5 the highest. Gfr not super high ( just don’t remember) is in the lower end. And Im heart transplant patient and I exercice 45 years old. I urinate a lot and always show signs of dehydration in my lab work. My concern is if I already show signs of dehydration doesn’t taking the med would make it worst. Ps. No prostate problem. Sometimes I can’t even have a good night sleep because of urinating so much. Thanks for the explanation. You have answered more questions in your channel without me having to look’em up that is amazing. ❤
@emmanuelaguilar1745
@emmanuelaguilar1745 10 күн бұрын
You are doctoring yourself!
@Motts9668
@Motts9668 11 ай бұрын
Hi, this was helpful. Can you guys also discuss GLP1 meds as well and compare to SGLT2 for CKD? thank you!
@maomama5980
@maomama5980 Жыл бұрын
Hi Dr Thank you again for another highly informative video. Is SGL2 inhibitors effective on none diabetics GN patient? Thank you again
@endysgarden
@endysgarden Жыл бұрын
Do you all know any studies linking kidney disease and properties of adaptogen mushrooms?
@tanyaalexander9387
@tanyaalexander9387 Жыл бұрын
dr Hashmi is it ok to take with a arb that has a diuretic? My bp meds has a diuretic so will that cause a problem?
@westfield90
@westfield90 11 ай бұрын
Hoping this will help my dad who has CHF and constant fluid buildup in the legs and lungs. Hopefully if sodium is excreted then logically less interstitial fluid build up.
@yeonheebuehler9140
@yeonheebuehler9140 Жыл бұрын
I take sglt 2 and linsinopril . Is this ok?
@robertrayder858
@robertrayder858 Жыл бұрын
Excellent presentation. I am on Sglt2 inhibitor and recently was increased to 25mg as my HgbA1C went into diabetic range, I have been on the medication 3 months. Should I be concerned that my GFR went lower from 51 to 49 on medication and when would the medication increase or stabilize the GFR?
@ashleysolomon691
@ashleysolomon691 4 ай бұрын
In my case the eGFR went down but climbed back up in about 3 odd momths
@deusvlad2.083
@deusvlad2.083 Жыл бұрын
Maybe using activated charcoal capsules before eating anything will be able to help by absorbing the toxins from the bad foods and helping reduce kidney use thus helping kidney recovery?
@philipcyhowski1846
@philipcyhowski1846 Жыл бұрын
I’m curious to know would you prescribe this for Someone with microscopic hematuria and proteinuria? Over an ACE/ARB? and If they are already being controlled with an ARB?
@ivory8844
@ivory8844 Жыл бұрын
I did try the medication it raised my sugar level over 150 , I did not like the medication. I will stick with lisinopril
@HeyYall398
@HeyYall398 Жыл бұрын
The assertion made in the preceding statement regarding a 14% reduction in all-cause mortality requires clarification, as it inaccurately conflates the concept with relative risk reduction (RRR). It is important to note that the reported figure of 14% pertains specifically to the RRR, rather than the reduction in all-cause mortality. In truth, the reduction in all-cause mortality associated with the intervention in question amounts to a modest 1.6%. Drawing upon evidence from the JARDIANCE trials, it is indeed accurate to state that JARDIANCE demonstrated a relative risk reduction of 14% (hazard ratio [HR] = 0.86, 95% confidence interval [CI]: 0.74-0.99, P = 0.04). However, it is essential to distinguish between RRR and absolute risk reduction (ARR) when considering the implications of these findings. In the context of the composite endpoint, the ARR observed was merely 1.6%. By emphasizing the distinction between RRR and ARR, it becomes evident that the reduction in all-cause mortality attributable to the intervention is considerably more modest than the initially stated 14%. The nuanced interpretation of the JARDIANCE trials underscores the need for accuracy and precision when discussing the effects of medical interventions, particularly with regard to outcomes as critical as all-cause mortality.
@emmanuelaguilar1745
@emmanuelaguilar1745 10 күн бұрын
This is a nonsense answer. Research more.
@bobcocampo
@bobcocampo Жыл бұрын
Can SGLT2 INH Help reach autophagy faster?
@Roberto-cg2gr
@Roberto-cg2gr Ай бұрын
Any research with zero carb combined with SGLT2 INHIBITOR or fasting and SGLT2 INHIBITOR?
@chazlon5061
@chazlon5061 Жыл бұрын
I heard apple peel powder is a natural sglt2 inhinitor...I wonder 🤔
@carmenlombere2529
@carmenlombere2529 5 ай бұрын
What about GLP-1-R
@fraseredk7433
@fraseredk7433 11 ай бұрын
Stage 3 ckd and high-ish bp. Do you prefer losartan or verapamil ?? Please advise. Thanks.
@emmanuelaguilar1745
@emmanuelaguilar1745 10 күн бұрын
See your doctor!!!!!
@jamiew7306
@jamiew7306 Жыл бұрын
Hi, did you say all cause mortality dropped by 40% or 14%? Thanks
@paulabrown5243
@paulabrown5243 10 ай бұрын
14%
@nicm3155
@nicm3155 Жыл бұрын
Is Metformin safe for patient ckd
@PlantBasedKidneyHealth
@PlantBasedKidneyHealth Жыл бұрын
We have an episode coming out on that soon! Stay tuned.
@nicm3155
@nicm3155 Жыл бұрын
@@PlantBasedKidneyHealth thx to miss Michelle and dr Hashmi, I appreciate your answer in the podcast about metformin
@Roberto-cg2gr
@Roberto-cg2gr Ай бұрын
Zero carb improve my HBA1C from 10.2 to 5.2 in 3 months with fasting
@kevinwellwrought2024
@kevinwellwrought2024 20 күн бұрын
Farxiga increases ketones which are bad for kidneys, also UTI is very bad for kidneys and prostate!
@emmanuelaguilar1745
@emmanuelaguilar1745 10 күн бұрын
Are you ignorant? You just have to drink more water!!!!!!!!
@kevinwellwrought2024
@kevinwellwrought2024 10 күн бұрын
@@emmanuelaguilar1745 you seem to have no knowledge of medicine and most probably no schooling! You want to destroy ketones and glucose with water??😂😂😂😂😂
@00dfm00
@00dfm00 Жыл бұрын
Finerenone ?
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