What Do Vitamins Actually Do? (Vitamin Lore)

Рет қаралды 955,813

Күн бұрын

Thanks to Bespoke Post for sponsoring this video! New subscribers get 20% off their first box of awesome - go to bespokepost.com/thatchemist20 and enter code THATCHEMIST20 at checkout.
This is the Vitamin Tierlist - vitamins play many important roles in our bodies and the biochemistry that vitamins do is pretty neat!
Support the Channel on Patreon - / thatchemist
Join the Community Discord! - / discord
0:00 Intro
2:45 sponsor
4:43 A
11:34 B1
17:24 B2
19:56 B3
22:45 B5
24:30 B6
27:09 B7
28:24 B9
30:29 B12
31:47 C
35:48 D
38:09 E
41:38 K
Team
Writer/Producer - That Chemist (Joey)
Editor/Animator - ReformLabs
Research/Production Assistant - Exergonick
Technical Lead - Polygorg (Georg)
3D Systems Engineer - Robot Chicken
Acknowledgements
This video was made possible with help from several members of the TC Discord Community, especially Gocker (protein modelling expertise) & Ballerene (biochemistry expertise). Also ‪@ExplosionsAndFire‬ !
_________
References
Neurotoxin Tierlist • Which Neurotoxin is th...
Medicosis (corn tortillas) • Pellagra (Vitamin B3 D...
Vitamin B12 part 1 • R.B. Woodward Total Sy...
Vitamin B12 part 2 • R.B. Woodward Total Sy...
‪@MedicosisPerfectionalis‬ • Biochemistry (New)
General nutrient information www.ncbi.nlm.nih.gov/books/NB...
First vitamins doi.org/10.4066/AMJ.2013.1588.
Essential Nutrient an overview www.sciencedirect.com/topics/...
Early vitamin paper doi.org/10.1246/NIKKASHI1880.....
Fat Soluble Vitamins www.ncbi.nlm.nih.gov/books/NB...
Water Soluble Vitamins www.ncbi.nlm.nih.gov/books/NB...
Vitamin K ods.od.nih.gov/factsheets/Vit...
Vitamin A and Carotenoids ods.od.nih.gov/factsheets/Vit...
Vitamin A and retinoid signaling www.ncbi.nlm.nih.gov/pmc/arti...
Consequences of Vitamin A Deficiency doi.org/10.3390/IJMS21155570
Vitamin A Toxicity www.ncbi.nlm.nih.gov/books/NB...
The Golden Rice Project www.goldenrice.org/
Thiamine ods.od.nih.gov/factsheets/Thi...
Dry Beriberi in a Man doi.org/10.1186/1752-1947-4-409
Beriberi. doi.org/10.1016/0306-9877(95)...
Relevance of N-Heterocyclic Carbenes pubs.acs.org/doi/10.1021/jo30...
Thiamine Pyrophosphate an overview www.sciencedirect.com/topics/...
Riboflavin ods.od.nih.gov/factsheets/Rib...
Niacin ods.od.nih.gov/factsheets/Nia...
Nixtamalization www.sciencedirect.com/topics/...
Nicotinic Acid Deficiency an overview www.sciencedirect.com/topics/...
Pantothenic Acid ods.od.nih.gov/factsheets/Pan...
Vitamin B6 ods.od.nih.gov/factsheets/Vit...
Biotin ods.od.nih.gov/factsheets/Bio...
Folate ods.od.nih.gov/factsheets/Fol...
Vitamin B12 ods.od.nih.gov/factsheets/Vit...
Vitamin C ods.od.nih.gov/factsheets/Vit...
Vitamin D ods.od.nih.gov/factsheets/Vit...
Vitamin E ods.od.nih.gov/factsheets/Vit...
Vitamin K ods.od.nih.gov/factsheets/vit...
Vitamin digestion and absorption - www.kegg.jp/pathway/map04977
Biosynthesis of cofactors - www.kegg.jp/pathway/map0124
Pathway information:
Vitamin A Retinol www.kegg.jp/pathway/map00830
Vitamin B1 Thiamine www.kegg.jp/pathway/map00730
Vitamin B2 Riboflavin www.kegg.jp/pathway/map00740
Vitamin B3 Niacin www.kegg.jp/pathway/map00760+...
Vitamin B5 Pantothenic Acid Beta alanine metabolism www.kegg.jp/pathway/map00410
CoA synthesis www.kegg.jp/pathway/map00770
Vitamin B6 Pyridoxine www.kegg.jp/pathway/map00750
Vitamin B7 Biotin www.kegg.jp/pathway/map00780
Vitamin B9 Folate/folic acid www.kegg.jp/pathway/map00790
Vitamin B12 Cobalamin www.kegg.jp/pathway/map00860+...
Vitamin C Ascorbic acid www.kegg.jp/pathway/map0005
Glutathione www.kegg.jp/pathway/map00480
Vitamin D steroid biosynthesis www.kegg.jp/pathway/map0010
Vitamin E Tocopherol www.kegg.jp/pathway/map00130+...
www.kegg.jp/pathway/map01110+...
Vitamin K Phytonadione www.kegg.jp/pathway/map00130+...
Relevant human Proteins found in RCSB PDB RCSB.org 10.1093/nar/28.1.235
And predicted proteins found at www.uniprot.org/

Пікірлер: 1 400

@That_Chemist Жыл бұрын

New Bespoke Post subscribers get 20% off their first ”box of awesome” - go to bespokepost.com/thatchemist20 and enter code THATCHEMIST20 at checkout. Thanks to Bespoke Post for sponsoring!

@topcatcoast2coast579 Жыл бұрын

Loved watching you nerd out with Hamilton Morris on his channel. I love how visibly excited yous all get👍📌

@sebastianmaier5328 Жыл бұрын

Thanks alot

@theulfhednar3915 Жыл бұрын

You are Amazing, keep the amazing work

@That_Chemist Жыл бұрын

@@sebastianmaier5328 thanks! that's actually a decent idea - I will share it with the team :)

@delquandrecolter3477 Жыл бұрын

Pyruvate t9 goucatonatw 😊

@tristanlaurent5785 Жыл бұрын

I'm starting to like biology... and it scares me

@That_Chemist Жыл бұрын

same tbh

@testingtesting421 Жыл бұрын

Biochemistry is a wonderful middle ground. Enzymes catalyze some amazing reactions through interesting mechanisms. Biomolecules also have very interesting characteristics and structural motifs.

@CrustaceousB Жыл бұрын

Just wait until you find sacred geometry. Pretty patterns got me enjoying MATH 😂

@jtgd Жыл бұрын

What if I told you, biology is a great field parallel to computer science?

@szxnv Жыл бұрын

one of us.. one of us...

@Verinius Жыл бұрын

Dude I love how science content creators are using trendy KZfaq stuff to teach science. I am easily baited into science videos with titles like "Vitamin tier list" "Are giraffes OP?" "Scientific theory iceberg"

@rilmar2137 Жыл бұрын

I have no background in chemistry. I know very little about chemistry. However, your videos are a joy to watch

@That_Chemist Жыл бұрын

I hope you learn something useful from the videos :)

@othman3049 Жыл бұрын

@@That_Chemist good evening sir, can you recommend a chemistry fundamentals textbook? especially organic chemistry

@That_Chemist Жыл бұрын

@@othman3049 Clayden is pretty good, especially if you find mechanisms to be helpful - chemlibre texts is another free online resource

@Rileydog53 Жыл бұрын

you’re putting out some of the best chemistry content on youtube right now. thank you.

@That_Chemist Жыл бұрын

I will share your kind words with the team :)

@Exergonick Жыл бұрын

😳🥰

@sm00gzbear Жыл бұрын

The best of course being Nile green.

@ayo9057 Жыл бұрын

@@That_Chemist imagine if we could absorb vitimins.

@charismauniversity9626 Жыл бұрын

You are welcome 😊

@memaimu Жыл бұрын

Spoilers: Vitamin B1 Thiamine, Vitamin B3 Nicotinamide, Vitamin B6 Pyrodoxine, and Vitamin B12 Cyanocobalamin are the GOAT according to this guy.

@That_Chemist Жыл бұрын

Yes they are - very cool chemistry 😎

@freigeist777 3 ай бұрын

Cyanocobalamin is a kind of useless form of B12 for our body, the orther 3 isomeres work though

@estellagrace7276 Жыл бұрын

Fun fact about Vit K - it is given routinely to babies right after they are born (usually via IM injection or occasionally oral supplementation) because they are naturally low in it and don't yet have the gut bacteria that produce it which as explained in the video can affect blood clotting. It reduces the rate of intracranial haemorrhage which can cause brain damage - particularly important for babies who have had more traumatic births (i.e. vacuum or forceps assisted births).

@mauz791 Жыл бұрын

Interesting fact, thanks for sharing!

@roddydykes7053 11 ай бұрын

Oh yeah I got vacuumed out of my mom’s cnut. Hardly ever hear anyone bring that method up

@SoulDelSol 10 ай бұрын

@@roddydykes7053that's terrible. Sounds like they screwed that up. I don't think you're supposed to suck a baby's skull on a vacuum to point you can pull him around even when stuck! Or wrap bbq tongs or forceps or whatever around its face and yank him out. I bet it feels like being constipated except there are no farts to help push it out

@jopainting1668 10 ай бұрын

These comments are.. awful.

@dmonburner8791 9 ай бұрын

on the 8th day the baby begins producing its own, hence why jewish people wait until the 8th day for circumcision

@deliriouscookie3107 Жыл бұрын

Now we need a sequel by Ex&F on how to make explosive vitamins :D

@ExplosionsAndFire Жыл бұрын

"what's the healthiest explosive"

@Sniperboy5551 Жыл бұрын

@Explosions&Fire I love you, Tom. No homo. Nice collab with Cold Ones, it reminded me just how much I miss new uploads from you.

@danielhonetschlager8508 Жыл бұрын

@@ExplosionsAndFirewe need an answer

@MandrakeFernflower Жыл бұрын

@@ExplosionsAndFire nitroglycerin is used as a medicine so maybe its that one

@benjaminmiller3620 Жыл бұрын

*Ascorbic acid* is actually used to make a rocketry propellant! It's called crimson powder and I believe it's primarily used in ejection charges as a more potent, cooler burning, alternative to black powder.

@jackal7905 Жыл бұрын

Speak more biochemistry, please. This video is so satisfying.

@ArkonArchive Жыл бұрын

So basically: Eggs have everything you need.

@ananthropomorphictalkinggo6641 Жыл бұрын

Of course they do, that's literally their sole reason for existing.

@xenoblad 8 ай бұрын

They have a lot of stuff, but no fiber or vitamin c. Depending on if you think excess cholesterol is bad, eggs can be an issue in that area.

@illegal.anglo88 8 ай бұрын

@@xenobladfiber is not a nutrient and is bullshit. Cut out fiber and you actually poop better. In terms of vitamin C it’s actually only necessary if you eat carbs. It’s too complicated to explain why through text but you can google why. In terms of cholesterol our liver produces more cholesterol than we can possibly consume so why is it bad for us? So really eggs do have everything we need.

@anthonysoprano7066 7 ай бұрын

@@xenobladthe cholesterol worries with regards to eggs is bullshit.

@epitaph8704 7 ай бұрын

@@xenobladIf you need Vitamin C, it comes in cans

@hydrogenbond7303 Жыл бұрын

There's funny way to memorize the vitamins soluble in fats in Czech language - the word for butt (which contains fat) is "ZADEK" and If you take out the "Z" you get the vitamins soluble in fat - "ADEK" :D

@jenda386 Жыл бұрын

The really important thing is to remember that the fat-soluble vitamins are not R, D, E and L.

@timkurz6086 Жыл бұрын

In German too we memorize them by EDEKA a common grocery store here

@awli8861 Жыл бұрын

"Zadek" is also a word for butt in Polish language

@viktordelac5294 Жыл бұрын

In croatian DEKA means blanket so it works

@Nov1cegg Жыл бұрын

In Brazilian Portuguese, "keda" sounds exactly like "queda", which means falling. So I memorized it as "if you slip on it (cause fat is slipper), KEDA"

@jreelite7149 Жыл бұрын

The colored functional group atoms makes my brain feel good. You did an amazing job with this. Excited for the one.

@That_Chemist Жыл бұрын

I can't take all the credit - it is only possible thanks to the whole team!

@peggedyourdad9560 Жыл бұрын

@@That_Chemist Then you have an amazing team.

@inhisname8395 10 ай бұрын

Carnivore diet is the best

@MedicosisPerfectionalis Жыл бұрын

🤩 Thank you so much for mentioning my video! I appreciate you!

@That_Chemist Жыл бұрын

I appreciate your videos a lot - keep up the incredible work!

@MedicosisPerfectionalis Жыл бұрын

@@That_Chemist Thank you 🙏

@TehLiquid Жыл бұрын

You can also get Vitamin-E from Eggs, just like Vitamin-B1, B2, B5, B6, B12, Biotin, Choline, Folate, Vitamin-A, D, E and K2. Along with (And I know these aren't Vitamins, but still..) Iodine, Iron, Phosphoprus, Selenium, Sodium and Zinc. They're literally a perfect food.

@perad1895 Жыл бұрын

from a organic, actual free range, good diet having chicken you may yes. not from just any eggs.

@ssgoko88 Жыл бұрын

@@perad1895 could you explain how an egg could even be made without these essential materials I'm pretty sure it's any egg.

@perad1895 Жыл бұрын

@@ssgoko88 quality of and egg....depends on the quality of the chicken....the quality of the chicken depends on the quality of its lifestyle. simple borskie....not sure what you asked me to be honest.

@HousemaidMomoSakura Жыл бұрын

@Pera 'D i think they were confused about "not just any eggs" and might have assumed you implied eggs from other animals lacked some of the qualities of chicken eggs, since you specified "chicken eggs" earlier in the comment, so they asked you to elaborate on that. I might be wrong tho.

@perad1895 Жыл бұрын

@@HousemaidMomoSakura gotcha..talking about chicken only here....but regardless my point of the animal and its living condition = quality of the egg. don't change. but thats the same for any good food tbh.

@maxr1104 Жыл бұрын

As someone who’s just getting off of accutane myself, I think understanding the chemical processes behind why my skin excessively dried out and my dozens of nose bleeds would be interesting to see! As always thank you for the effort you put into these videos!

@zachsuarez1830 Жыл бұрын

Same

@dinglesplat3281 Жыл бұрын

Same

@davidhagersten8447 Жыл бұрын

@Max R Read any of Grant Genereux's three free ebooks on vitamin A. Grant Genereux has been on a low vitamin A diet for +8 years. Too bad you have been damaged by a high dose retinoic acid in accutane.

@pabloescobar4029 Жыл бұрын

Don’t take that shi

@Gairith Жыл бұрын

Whoa they still make accutane? I thought it was lawsuit'd out of existence Fun story: out of shameful habit, I went to pop a zit while on my first month of accutane. The dry skin under my fingertips just slid off instead

@balazsbelavari7556 Жыл бұрын

so in hungary (where I live) there is a big thing about vitamin c, because one hungarian scientist got the idea of extracting it from peppers and he did so succesfully. So apart from citrus fruits, peppers (as in paprika) should be good too. (go look it up if you want it’s Albert Szentgyörgyi and it’s a whole thing, there aren’t a lot of hungarian contributions to science so the ones we did make are super hyped up in every school)

@Yarmox Жыл бұрын

There are MANY Hungarian scientific contributions. Ignaz Semmelweis is the reason many many babies have survived being born. Just one significant example. Szeresed magad, koszonom.

@jamham69 Жыл бұрын

"this is the more complicated part" is THE funniest shit. you lost me immeditaly the moment you started talking and, 5 minutes into an endless string of chemical names, you say "now it gets complicated" Perfect. i love this channel so much

@sealpiercing8476 Жыл бұрын

I'm starting to wonder if part of the historical success of wheat-based diets might have been due to growing yeast in it. Not just a little bit to raise the bread, but a lot of it so the yeast can synthesize some vitamins.

@That_Chemist Жыл бұрын

Honestly I’ve thought about this as well

@JotaC Жыл бұрын

Beer and wine were literally more drunk than water back in ancient civilizations, not only because it was safer, since it was less likely to get infectious disease from alcoholic beverages than it was to get from contaminated water, but also because those beverages were found to have an effect on reducing the amount of "diseases" (aka deficiencies) that people had.

@That_Chemist Жыл бұрын

most wines in ancient times tended to be drugged wines too - The Immortality Key discusses this at greater length

@Yuhyuhmuhmuh Жыл бұрын

@@JotaC sorry Jota, but that's a myth. People have always drank more water than anything else until recently when canned beverages became cheap than bottled water

@sashboo1370 Жыл бұрын

I have said before how your videos are really improving, but this one is like none other before. The visual support is clean, the memes are funny and the information is easy to comprehend. Amazing job!

@barefootalien Жыл бұрын

Regarding finding local edible plants with needed vitamins... I would assume that in most places humans have lived for an appreciable length of time, people have pretty much figured out what plants are edible pretty effectively. Finding an edible plant that's also palatable and cultivatable and fills a gap in human needs in an area, that nobody knows about should be exceedingly rare.

@madboycal7859 Жыл бұрын

Your production in videos has gotten a lot better over time (not saying your prior videos are bad). This is S tier content.

@alexd4102 Жыл бұрын

Poggers

@KittenRaptor 8 ай бұрын

I've been dealing with nutrition in a macro sense for many years, and until today I had no idea Vitamin B12 was a Cobalt complex.

@chayaropsrirattanawong203 Жыл бұрын

This some of the best-summarized versions of biochemistry that we (basic medical science ie. doctors, dentists, medical science, etc.) have to learn in my country for this particular topic. We just basically remember all the B vitamins as (1-PPP, 2-FAD, 3-NAD, 5-CoA, 6-transaminase, 7-CO2 transporter, 9-nucleotide synt, 12-Cobalt version of heme). Usually, we only got the text with some pictures but not the whole pathway (only the significant one) to study not to mention that every vitamin plays a role in understanding how our body works (you need to understand the basic pathway of metabolism first + heme synthesis). It is a fascinating topic and I admire how you presented it in an easy-understandable way for a topic that is mostly oversimplified to good-bad benefit.

@That_Chemist Жыл бұрын

Thank you! It really helps when people share it so that it can reach as many people who would benefit as possible :)

@da3m0nic_79 Жыл бұрын

Amazing production on this one. Your team is amazing

@That_Chemist Жыл бұрын

They are indeed :)

@nolanhanson5743 Жыл бұрын

@@That_Chemist What program is used to make the structures (and can I also make color coded letters with it?)

@medman4309 Жыл бұрын

@@That_Chemist yes! Whoever makes your graphics is doing an incredible job. Loved the TCA cycle one

@squeezter Жыл бұрын

Maybe even his best vid so far

@Exergonick Жыл бұрын

@@nolanhanson5743 it's a mix of blender, wavefronts from RCSB pdb's, and chemdraw. Those usually are consistent but honest we would use anything as long as it shows what we would like to show effectively.

@PitBullSerbian Жыл бұрын

Vitamin D deserves S tier, you undersold it's effects so hard. Maybe it's boring from a chemical standpoint, but from biochemical and endocrine it's not.

@quinnlintott406 Жыл бұрын

Hands down the best chemistry content on youtube. I really like that you touch on adjacent topics like psychopharmacology as well. Thanks for all your hard work!

@hevis6638 Жыл бұрын

One cool thing about biotin is its interaction with avidin. More specifically, the binding affinity of avidin to biotin is among the strongest non-covalent bonds. It's pretty much non-reversible without denaturing the avidin.

@randompillow5146 Жыл бұрын

Just wanted to say these videos are amazing to watch for me as an undergraduate chemistry student. It introduces me to aspects of chemistry I haven’t learned about yet and helps me be somewhat familiar with some things before I even learn about them in classes.

@That_Chemist Жыл бұрын

Great to hear!

@diablominero Жыл бұрын

Vitamin K2 supplementation has been found to be effective in preventing osteoporosis and some heart problems.

@VinsCool Жыл бұрын

I really like that new style of presentation going with the classic That Chemist voiceover

@Goldthecat 9 ай бұрын

I stg I learn more from KZfaq than I ever did in high school + college combined

@ekinyetkin Жыл бұрын

Damn i watched one of the best chemistry video on KZfaq. Great video bro

@That_Chemist Жыл бұрын

Thank you!

@ShockedCaucasian Жыл бұрын

Ooo Im excited! I love the production quality on these and ive been super curious about vitamins, Perfect combo!

@vitamincds735 Жыл бұрын

I like how you've updated your visual presentation! Your slides are colorful and fun to look at.

@drowzy_rick2718 Жыл бұрын

Please please please please make a detailed video on Acutane! I've read countless articles and research about how to works on a cellular level and I still can not connect all the pieces, however from what i did understand the drug is genuinely miraculous! I just got off two cycles and the symptoms were extremely wacky but I was left with perfectly clear skin at the end and my acne has not returned since. I had extreme dryness in my eyes, lips, skin, hair as well as joint pain in my knees and hips, tightness in my hips and pain in my lower back. I noticed i was far more injury prone and I even took longer to heal from injuries while I was on it. Really hope you take this suggestion into consideration as I think its near impossible detailed information on the drug even though its so widely used and talked about amongst teenagers struggling with acne. Love the videos and thank you so much!

@dhawthorne1634 Жыл бұрын

Nixtamalization of corn was also explained in Tasting History: Unwrapping Aztec Tamales as well as SciShow: Corn Shouldn't Be Food, But It Is. A walk-through of the full process can be found on Rose Red Homestead: How to Nixtamalize Dent Corn.

@GerinoMorn Жыл бұрын

Also, wasn't Golden Rice also better yielding in other nutrients? And I think it was thwarted by anti-GMO scare-tactics in developing countries...

@peggedyourdad9560 Жыл бұрын

I think is was also super hardy and able to grow in a variety of conditions, including during periods of less water.

@RepChris Жыл бұрын

Absolutely, greenpeace destroyed a lot of crops due to their purist views that put "not GMOs" over stopping preventable loss of human life

@josephkanowitz6875 Жыл бұрын

ב''ה, the full story is that apparently business reasons killed it

@akramisalah8189 Жыл бұрын

@@josephkanowitz6875 ב"ה?

@Exergonick Жыл бұрын

Its definitely not thwarted its still supported by private investment, but it does stand that nutritionally it wasn't better than normal rice it was evaluated twice by the FDA. But new generations of it will likely be introduced eventually and reevaluated. But at the time it was brand new and didn't deliver on promises at least in America. In Asia it was political resistance maybe somewhat anti GMO but more anti western influence.

@TigasCraft42 Жыл бұрын

This is amazing. Would love to see more biochemistry content here!

@applechocolate4U Жыл бұрын

Man I'm liking all the chemistry details in the editing. I'm a huge fan, and someone who really likes the videos you put out

@That_Chemist Жыл бұрын

I appreciate the kind words!

@sunbear2340 Жыл бұрын

I really appreciate the conciseness and precision of the script, some of the best ive seen in youtube educational content.

@That_Chemist Жыл бұрын

thank you!

@Demoralized88 Жыл бұрын

And he speaks so clearly and quickly. Tons of information in an interesting format even if I'm only able to comprehend some of it.

@afeathereddinosaur Жыл бұрын

Hrngh. These biologists, misnomering chemicals ánd these nutritionists claiming that food is good or bad. Did you see how the egg went from being healthy to being unhealthy to being healthy again to being unhealthy to being healthy now in a span of 40 years? Crazy stuff.

@That_Chemist Жыл бұрын

imo it's because most people don't understand the complexity of biology - hopefully they will after some more of these biochem videos 😎

@jamersbazuka8055 7 ай бұрын

BuT cHoLeStErOl

@ken198100 10 ай бұрын

Niacin was originally called nicotinic acid because it can be created by the oxidation of nicotine with nitric acid. However, people knew nicotine as the addictive chemical in tobacco, so the name niacin was used instead. Niacin comes from the words NIcotinic ACid vitamIN.

@iskander07 10 ай бұрын

Thank you

@maximusnickila4440 Жыл бұрын

This was my favorite tier list video, thank you Mr. That. Cordially, Maximus.

@cheloooxalfa6632 7 ай бұрын

amazing, clear, to the point, usefull ty

@totallynotagecko3866 Жыл бұрын

Hey, I know I’m a little late to the video but if you see this by any chance could you start adding the IUPAC names under the graphics of molecules? Especially the hydrocarbons. I’m in grade 12 chemistry right now on the organic chemistry unit and it would be a massive help in reinforcing what I’m learning

@diablominero Жыл бұрын

There've been some exciting results in aging reversal in lab mice using niacin derivatives.

@JOJO-yd7qs 9 ай бұрын

i really appreciate this. I think it’s interesting to hear about vitamins with out a huge health hype and miss information.

@guilhermmmendes3766 11 ай бұрын

nice video bro. Helped so much

@jeremiquirus1958 Жыл бұрын

Something that fascinates me is how essential amino acids like phenylalanine and tryptophan have cyclic carbon rings that arent formed in animals bodies. We are reliant on plants and microorganisms for the building blocks of our bodies.

@deltalima6703 Жыл бұрын

??? No they dont.

@user-jr3zr2mp9c 8 ай бұрын

Yes thats how omnivores work

@amentrison2794 Жыл бұрын

As someone in a biochem program, your stock exchange analogy actually confused me for a brief moment lol. I had to use my knowledge of coenzymes to understand the analogy rather than the other way around. This was a fun video. More bio stuff please!

@deltalima6703 Жыл бұрын

Lol

@kalebjacobs111 7 ай бұрын

wow I just love watching such long, in depth videos and finishing the video- forgetting every last detail learned

@GerinoMorn Жыл бұрын

This is my favourite type of videos: chemistry in biomedical context

@trulyinfamous Жыл бұрын

I haven't watched this channel in a while and so far I'm liking the changes to the format. The glow effect on some of the text makes it look like my vision is blurry though.

@MRgun202 Жыл бұрын

Adding one thing, Umetaro Suzuki was working on vitamins but originally term "vita-aminy" was created by Casimir Funk in 1912 who created concept of vitamins

@icycrusader1947 Жыл бұрын

And then Funk was credited with the discovery of B1...despite likely discovering B2.

@blackout6179 Жыл бұрын

Recommendation: Tier list of amino acids / supplements, like: Citicoline, GDP, NAND, NAN+, N-Acetyl-L-Tyrosine etc..

@catoverlords9560 3 ай бұрын

I have a lot of health anxiety and thus, have a hard time appreciating my body. This video helped me change my attitude - if my body can do all these crazy biochemical reactions and conversions, it deserves some respect. Thank you for your content. I appreciate it and the team a lot.

@aleksandrskidan9262 Жыл бұрын

This is definitely the best video about vitamins I have ever seen, it was really detailed and I loved every second of it, have you thought about doing similar video about minerals?

@That_Chemist Жыл бұрын

I haven't thought a ton about minerals (rocks), but in terms of biominerals we could definitely do something like this in the future

@PaulSteMarie Жыл бұрын

@@That_Chemist Geology Hub frequently refers to the chemical composition of lava, typically silica vs alkali metals, but geologists in general have their own rather odd way of categorizing minerals (felsic vs mafic). Toss in the the weirdness of clay minerals and you've got lots to talk about.

@MikeIsCannonFodder Жыл бұрын

Based on what you said about B12 maybe this changed, but folic acid was usually recommended to pregnant women in part to help prevent neural tube defects.

@Exergonick Жыл бұрын

Its both, folic acid has been known for a while, but "recently" b12 was also shown to independently reduce the risk. Nature Reviews Endocrinology volume 5, page 354 (2009)

@MySuperhappyfuntime Жыл бұрын

I really love the colour scheme and the editing on this video. Well done.

@TsukaiKugatsuGA 7 ай бұрын

This is so f-ing nerdy I love it Thanks for the awesome video!

@Ophiuchus97 11 ай бұрын

Mineral tier list?

@carolinewhite9678 Жыл бұрын

I would really appreciate the video on Vit A, specifically accutane. As I think about starting a course but I'm terrified of nose bleeds more than anything else.

@siemkamsteeg4536 6 ай бұрын

I like how you describe everything in such details it helps me understand and remember it way better, is there an Accutane video also?

@jercos Жыл бұрын

Your animation and overlay work is getting amazing, really adding the the draw of the content. The visible complexity of the spinning enzymes involved in the Krebs cycle drives home how amazing that machinery is as a whole without saying a word. When looking at inputs and outputs it seems all too simple, but it's a ladder of the same complexity as the mitochondrial electron transport chain.

@That_Chemist Жыл бұрын

Thanks! We have some more cool changes coming in the next tierlist we will be posting (hopefully in the next few days, definitely before the end of May)!

@That_Chemist Жыл бұрын

I don’t make these by myself anymore, but rather we have a team of people who are dedicated to working on it :)

@kyuofcosmic Жыл бұрын

B12 is so cool, it’s also an antidote for cyanide poisoning!

@Zoominguy007 8 ай бұрын

Putting them all in a tier list really helped me differentiate and remember them and their roles in the body. Absolutely genius video formatting thank you!!

@martensamulowitz347 Жыл бұрын

man the production quality of this is crazy

@Jackieception 7 ай бұрын

love that touch of humor. "i just wanna express myself bro" .. A vitamin: "NO" . these kinds of teachers is what the world needs

@emyyyxx Жыл бұрын

i’m on accutane and there’s so much misinformation out there but it still kinda scares me. would love a video on it (:

@yahia9481 Жыл бұрын

What s that ?

@Vacced Жыл бұрын

@@yahia9481 gets ride of acne, has many side effects

@feelinghealingfrequences7179 10 ай бұрын

or consider not being on a poison moreplatesmoredates and leo and longevity covers accutane

@bellenesatan 9 ай бұрын

@@feelinghealingfrequences7179 your name is "feeling healing frequencies" you probably think 5G is deadly sit the poison talk out

@GerinoMorn Жыл бұрын

Oh, and I'm so up for a video about various retinoids, especially how newer generations like adapalene are causing less/none photosensitivity in skin!

@zachsuarez1830 Жыл бұрын

I would love one about all the skin stuff like even comparing the different chemicals and stuff or whatever in each retinitoid also that’s cool they don’t cause photosensitivity is there a way maybe to make acutane do that? I though photosensitivity was becasuw it made skin cycle faster so it was new skin which is easy to burn

@manniemintea9098 7 ай бұрын

Thank you! I love Bio and chem and everything in between, Definitely going to watch again!

@EpicDeception Жыл бұрын

This is amazing. It's all I've ever wanted. Thank you.

@Ksweetpea Жыл бұрын

My winter depression was largely a crippling vitamin D deficiency spiced up with ADHD and general anxiety disorder 😂

@qybe6330 Жыл бұрын

Same

@tremarley9648 8 ай бұрын

Most people are deficient in vitamin D today

@AcousticTelevisions 7 ай бұрын

Eyyy SAD-ADHD-anxiety gang

@NeutronMicrowave 7 ай бұрын

les goooo

@rubyblindheim4572 11 ай бұрын

I would absolutely love a video on carotenoids, beta carotenes, acutane, etc. Thank you for such educational and informative content!😊❤

@johns1625 10 ай бұрын

Very curious about acutane. I took that when I was a teenager and although it was the only thing that actually cured my acne it had some marvelously horrible effects on my skin, like a desiccated piece of flaky jerky covered in cold sores. Like my entire lips were just one big cold sore. Never had one after that nor before.

@hhvhhvcz Жыл бұрын

i loved every second of this video, could you pretty please do also follow up with periodic elements and include simple compounds e.g. Li, Fe, Mg, NaCl etc

@CharChar2121 Жыл бұрын

I've been needing this my entire life.

@jarnodavidson3432 Жыл бұрын

I really like the new new format like a bit of info and I also like the new colours

@MohammadChughtaiH 10 ай бұрын

This is so complicated for a tier list man... I feel like I need to be a biologist to understand. Wish you had simplified to make this more accessible.

@hanabe Жыл бұрын

yes please do make a video on Accutane so I can know what exactly it did to my body during and post treatment

@markparker5585 11 ай бұрын

Apologies if someone has already pointed this out, but there is a graphics error at 37:05, where it should show D2 for the plant based form, not D3.

@MrTimebomb12 Жыл бұрын

Even though I don't understand half of this stuff I do generally get the idea. I just love these kinds of videos because I get to appreciate how beautifully complex nature is.

@ikosaheadrom 10 ай бұрын

I have to put the video in x0.75

@6alecapristrudel Жыл бұрын

Biotin/B7 is S tier! Not because of sulf*r, but because Shiny! I use B7 as brightener in my "buy it at the pharmacy" shiny copper plating bath formula. Vitamin C is S tier because it's the reducing agent of choice for my electroless/chemical Silver bath. Niacin seems interesting for silver too but I haven't played around with it yet.

@user-er6ey2kz4e 8 ай бұрын

What an awesome overview! Gonna watch it right over again

@Dave2713 8 ай бұрын

I like your channel, good blend of humor sprinkled into very digestible information.

@DrobisPR Жыл бұрын

A year out from my BS in biochem , and I'm glad you brought up how yellow flavins are! Was the first quality my professor mentioned in intermediary metabolism and I was thinking, "wonder if E&F knows". Thank you for the great content!

@nirodper Жыл бұрын

It gives a nice color to your pee after eating liver :D

@evanixiast Жыл бұрын

"Fat soluble vitamins are less likely to cause deficiency" me having a severe vitamin D deficiency last year and having to take a lot daily because I'm allergic to sunlight ☺

@stanlevox2291 Жыл бұрын

Would totally like a video on astaxanthin been reading all the NIH and pubmed studies. Trying even to ask chatgpt3 how to achieve that orange colored skin that can happen with astaxanthin as well. I did 100mg daily for a few months from 2 different brands and didn't achieve that orange result. My eyesight improved along with taking Sulbutiamine and Astaxanthin from negative 1.25 to 0.75 (fR sighted) along with (convuluted with rather) eye exercises daily. Over the course of 1 year, going to try and add NMN to get back to not needing to wear contact lenses. Also added bacopa and lions mane extract to the mix, 2 grams and 5-10 grams respectively. (Also increased potassium (Kiwi, greens) and magnesium glycibate due to sulbutiamine utilizing more uptake).

@hummusslurp_8335 7 ай бұрын

As soon as I read the words "vitamin lore" I knew this was gonna be good, maybe I would've actually chosen that biology course if it was taught like this

@creamydistortion Жыл бұрын

Your channel is amazing. Even for amateur viewers who will probably never be in a lab (like myself), it's still just so interesting to learn about this stuff.

@That_Chemist Жыл бұрын

Thank you :)

@sydhenderson6753 Жыл бұрын

Riboflavin has given me quite a scare because if you consume an excess it come out in your urine and Riboflavin is astrobright yellow. (I don't think it's underrated in the tier list). I think he was entirely too clever with vitamin C and think he may have been influenced to put it into C tier because it was Vitamin C. It obviously is S tier given its important role in history.

@dirtpounder 7 ай бұрын

Vit c is tasty, should be up top on that alone.

@cloin9620 8 ай бұрын

This is such a good thumbnail. Nice one fr

@leafykille 11 ай бұрын

Wow this is awesome! So much chemistry:) I would love you to slightly extend the informative flash graphics so it's easier to pause on them to examine them in more detail.

@FreakySteph Жыл бұрын

As an undergraduate biologist I can say that Vitamin B7 is actually useful for detection experimental procedures in biology, since it forms complexes with avidin and maybe for that reason it should have been higher on the list (maybe D tier). But sulfur does suck and it does stink indeed. Anyway, I love how far your channel has come and the quality of your content has improved dramatically. Your videos are always extensively detailed and I thoroughly enjoy them. Even though I chose biology as my major, I do love chemistry and your videos remind me of how fun chemistry is while also enhancing my current knowledge.

@That_Chemist Жыл бұрын

Thank you for your kind words :)

@Jonas_Fox Жыл бұрын

I read an entire book on Vitamin K2 and the surrounding studies. Something about it as a coenzyme for proteins that transport calcium from and to tissues in the body, apparently really important in preventing atherosclerosis and reshaping bone during pregnancy and childhood growth. Book is called Vitamin K2 and the Calcium Paradox. They also cover some interactions between all the fat soluble vitamins. I'd love to see you tackle the chemistry behind these studies. Thanks for all you're doing here. 🤜🤛

@npi57 7 ай бұрын

Damn. Your content is getting sharper and sharper

@user-dg3ug7ny5d Жыл бұрын

I wish I had waltzed upon this video before submitting my multi-vitamins literature review! Trying to academically put that there is no standardised, regulated definition was a task and a half. This video definitely cemented how much I enjoy biochemistry, but the stress of studying higher-level chem past the required foundational level has me hesitating on it. It also means I need to study a level 200 chem unit before I reach the level 300 biochem units, so I at least have a year and a half, two years max before then if I want to get serious about it. Thanks again to you and your wonderful team! My brain has been most satisfied! :)

@Limuzins 11 ай бұрын

WTF is that food pyramid? How is sunflower oil healthy and red meat + butter unhealthy and compared to sweets???

@illegal.anglo88 8 ай бұрын

Because these people are brainwashed. Unnatural processed highly oxidized polyunsaturated fats = healthy and natural saturated fat that your body immediately recognizes = unhealthy. You can thank Ancel Keys for the destruction of our health. Even though nobody was having heart attacks over 100 years ago when people were eating mainly saturated fat.

@multiarray2320 Жыл бұрын

i dont actively watch your videos because i dont have to do a lot with chemistry, but this video was really enjoyable. was the quality of your videos always that good? i remember it a bit different (not meant to be insulting).