Depending on the situation, and this works best when having a dialogue between characters that are familiar with each other in my opinion, but having dry humor responses can add a little humor to the story. It's not gut busting, usually, but it can be used to deescalate a tense situation, sometimes. It can also work if a protagonist and antagonist are in conversation with either of them using it, either the protagonist, for example, using dry humor to show they aren't threatened by the antagonist, or the antagonist, let's say, belittling the protagonist's ideas. Here's an example. Let's say a hero is trying to get a villain to change their ways by telling them that there is good in them and the villain responds with something like, "So, I give up on all I worked for so I can join your little kumbaya therapy session to make me feel better? Give me a break!"