Dr. David Sinclair, a Harvard Medical School professor and New York Times bestselling author, was the guest of honor for the Institute for Systems Biology - Town Hall Science Series. He joined genomics pioneer and ISB Co-founder Dr. Lee Hood for a conversation that covered the very latest in aging research.
Learn More About Healthy Aging
isbscience.org/research/healthy-aging/
Publications
Wilmanski, T., Diener, C., Rappaport, N. et al. Gut microbiome pattern reflects healthy ageing and predicts survival in humans. Nat Metab 3, 274-286 (2021). doi.org/10.1038/s42255-021-00348-0
Baloni, Priyanka, Cory C. Funk, Jingwen Yan, James T. Yurkovich, Alexandra Kueider-Paisley, Kwangsik Nho, Almut Heinken, et al. 2020. “Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer’s Disease.” Cell Reports Medicine 1 (8). doi.org/10.1016/j.xcrm.2020.100138.
Wainberg, Michael, Andrew T. Magis, John C. Earls, Jennifer C. Lovejoy, Nasa Sinnott-Armstrong, Gilbert S. Omenn, Leroy Hood, and Nathan D. Price. 2020. “Multiomic Blood Correlates of Genetic Risk Identify Presymptomatic Disease Alterations.” Proceedings of the National Academy of Sciences of the United States of America 117 (35): 21813-20. doi.org/10.1073/pnas.2001429117.
Earls, John C., Noa Rappaport, Laura Heath, Tomasz Wilmanski, Andrew T. Magis, Nicholas J. Schork, Gilbert S. Omenn, Jennifer Lovejoy, Leroy Hood, and Nathan D. Price. 2019. “Multi-Omic Biological Age Estimation and Its Correlation With Wellness and Disease Phenotypes: A Longitudinal Study of 3,558 Individuals.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 74 (Supplement_1): S52-60. doi.org/10.1093/gerona/glz220.
Wilmanski, Tomasz, Noa Rappaport, John C. Earls, Andrew T. Magis, Ohad Manor, Jennifer Lovejoy, Gilbert S. Omenn, Leroy Hood, Sean M. Gibbons, and Nathan D. Price. 2019. “Blood Metabolome Predicts Gut Microbiome α-Diversity in Humans.” Nature Biotechnology. doi.org/10.1038/s41587-019-0233-9.