World’s Smallest Nerf Gun Shoots an Ant
Рет қаралды 49,741,585
7 ай бұрынCreating the World’s smallest Nerf gun 5 times in a row. Reserve your CrunchLabs Build Box for the holidays here- crunchlabs.com
I started a company called CrunchLabs, where we build a toy together, and then I teach you all the juicy physics for how it works. So if you want to learn to think like an engineer and have a really fun time doing it, check out the current promotion where you get 2 FREE boxes at crunchlabs.com
Thanks to these folks for providing some of the music in the video:
A Shell in the Pit - ashellinthepit.bandcamp.com/
Ponder - @pondermusic
Laura Shigihara - @supershigi
Andrew Applepie - / andrewapplepie
Blue Wednesday - / bluewednesday
Special thanks to my friends at BYU - Larry Howell, Brian Jensen, Spencer Magleby, Terri Bateman, Felipe Rivera, Jacob Sheffield, Grant Ogilvie, Bridget Kember, Bethany Parkinson, Aliya Bascom, James Wade, Hunter Pruett, Jared Hunter, Luke Gardner, Ivyann Running, Michael Linder, Brooklyn Peters, Jared Erickson, Austin Martel, Kyle Dahl, Julie Walker, Adam Sanders, Matt Michell and Barret Schoenrock.
Download files for compliant mechanisms that you can 3D print (including a compliant mechanism blaster): compliantmechanisms.byu.edu/m...
To learn more about the BYU Compliant Mechanisms Research Group (CMR), see compliantmechanisms.byu.edu/
Also, thanks to the very talented group of researchers from the Salk Institute, UC San Diego, and UC San Francisco: Lauren P. Takiguchi, Jocelyn G. Olvera, Amanda L. Wacker, Ryan J. Fantasia, Boyu Liu, and Pallav Kosuri, Wade Shipley of UC San Diego, and Konlin Shen, Roopal Rawani, Amy Cao, Mike Jeffs, and Victoria Johnson.
To read more about DNA Origami NanoNERF Blasters, please visit kosurilab.com/docs/Takiguchi-...
To learn more about Pallav Kosuri’s research and to support him in making DNA machines that improve human health, please visit www.salk.edu/kosuri. To support his work, click on the ‘give’ button and note ‘Kosuri Lab’ in the comments.
NO PURCHASE NECESSARY. Promotion starts on 1/1/2023 & ends on 12/31/23, subject to monthly entry deadlines. Open to legal residents of the 50 U.S. & D.C., 18+. 1 prize per month: each month is its own separate promotion. For the first 2-3 months, winner may be notified via phone call instead of winning game piece. If a monthly prize is unclaimed/forfeited, it will be awarded via 2nd chance drawing. See Official Rules at crunchlabs.com/sweepstakes for full details on eligibility requirements, how to enter, free method of entry, prize claim procedure, prize description and limitations. Void where prohibited.
@MarkRober 7 ай бұрын
Your move MrBeast. Get your CrunchLabs Build Box for the holidays!! crunchlabs.com
@Buzz0s 7 ай бұрын
okay!
@koekjemetmelk481 7 ай бұрын
mebeast?
@TheGrillSergeant 7 ай бұрын
Yes!
@rockyinspace492 7 ай бұрын
wait its been a minute hi mark
@shrekboy2324 7 ай бұрын
make the nerf gun atom size you wont
@gason1000 7 ай бұрын
it's amazing how Mark uses the nerf gun to hook u into watching and then secretly makes u learn all about scientists who actually deserve the exposure ❤
@pallavkosuri5606 7 ай бұрын
my students deserve a lot of credit! Lauren, Amanda, Jocelyn, Ryan and Barry were all amazing and helped make this happen! Mark was super down to earth and spent a lot of time talking to all of them - it was really a collaborative effort and so much fun to work together on this project!
@goldsharkau 7 ай бұрын
@@pallavkosuri5606 Incredible work you guys are doing!!
@Westwoodshadowgaming 7 ай бұрын
@@pallavkosuri5606 y'all's micro nerf guns were so cool! Absolutely blows my mind how y'all figured out how to make structures with DNA.
@gason1000 7 ай бұрын
@@pallavkosuri5606 It's truly heartwarming to hear that you appreciate the efforts of everyone involved. We're all thrilled by this project and are eagerly looking forward to your next endeavor.❤
@QUBIQUBED 7 ай бұрын
@@pallavkosuri5606 So is the plan to inject DNA bullets into cells using DNA structures? I love how passionate you are about your work, you have become a great inspiration for me. I can't believe things like this exist, people like you change the world. Thank you for what you do 👍
@Melone10001 7 ай бұрын
Im a physicist in Nanofabrication. This is impressive on another level. You made a video that children can watch that has more science inside than most lecture courses at university
@ThatCanadianMinecafter 7 ай бұрын
Cool
@schlafenKind 7 ай бұрын
Cool
@brentroundtree8310 7 ай бұрын
Great comment from the Nanophysicist guy! Exactly what I wish I could have said. And done so credibly and concisely. This video seemed a whole new level for Mr. Rober. It was technical enough that it allowed me to finally realize Mark Rober is currently one of the nearest this era can offer to Richard Feynman or Steven Hawking or the like. Or at least working at or near their level in his field of mechanical engineering.
@hamza-chaudhry 7 ай бұрын
Seriously more than a university lecture course?
@kaleinyo 7 ай бұрын
@@hamza-chaudhry University courses goes wide, not deep. Unless it's a course specifically designed around this subject/thematic, you don't get too much details about the content. For instance, I don't think you see how carbon nanotube are created (9:40) . Or how you can build stuff with DNA (not from DNA)
@Kathlanus Ай бұрын
What I love most about this video is 19:25. Give people like these a fun yet seemingley rediciulous project and you never know what kind of idea it sparks in their head.
@AVASdesertRACER 4 ай бұрын
i LOVED the detail of HOW a nerf gun works in the beginning. Mark Rober is the best KZfaqr out there, making science fun for kids, adults, dads, moms, everyone.
@MawaMaverick 7 ай бұрын
This guy pulls off something that is clearly extremely difficult to achieve and compresses it in a 20 minute video coupled with happy music. Well done.
@EEEEEEEE 7 ай бұрын
E
@just1m1s 7 ай бұрын
It's so amazing that they even make something like this
@aaroncampbell331 7 ай бұрын
His videos take months and months, some even years, and every time they’re worth it
@user-fm6jw2md3h 7 ай бұрын
No he didn't.. prove it
@user-fm6jw2md3h 7 ай бұрын
@@taap.on.my.pic790 hey.. I thought you were my friend! What are you doing talking to this guy??
@TimeBucks 7 ай бұрын
Love more detail on how the DNA was self building.
@pallavkosuri5606 7 ай бұрын
what do you want to know?
@zincerish 7 ай бұрын
@@pallavkosuri5606he replied!! You're a rockstar Pallav!!
@nancywake1051 7 ай бұрын
Probably build a couple strands then amplified each component via PCR - polymerase chain reaction, which uses a special DNA building molecule "taq polymerase" from a very heat resistant organism. Could be wrong though.
@gazvlogs7459 7 ай бұрын
Google this, "Enzymes Involved in DNA Replication"
@evitynaga9347 7 ай бұрын
👍
@annakalkman552 4 ай бұрын
I would LOVE if Mark created a second channel aimed at engineers themselves- I appreciate the explanations that everyone can understand, but so many of these videos bring me so many questions that are more in-depth that I would love to hear him explain more
@MaidenLoaf Ай бұрын
Thing is, such videos unfortunately take away from the time and resources needed to make these kinds of videos. I think he's wise to make things as accessibly explained as they are because it inspires people more generally. Having said that, as a fellow engineer, it would be nice, no question.
@squibbelsmcjohnson Ай бұрын
He is not a teacher lol
@athomesuperhero Ай бұрын
same
@grizzled1242 Ай бұрын
@@squibbelsmcjohnson he's effectively turned himself into one
@schwindsichtigaderechte5293 4 ай бұрын
This was nothing short of inspiring! And born from such a simple first idea! A true reminder of what creativity and brilliance the human spirit is capable of, and that - although some might stand out - it's usually not a single person's achievement, but a string of steps taken by a whole bunch of people that lead to mankinds' most amazing feats. Absolutely beautiful.
@th3milkman561 7 ай бұрын
I love how mark’s just like “this is so small, light cant even reflect off of it”. Just so casually as well.
@Jonny-wv2fc 7 ай бұрын
lol fr
@panda_314 7 ай бұрын
That's what she said
@jarrettshoup2709 7 ай бұрын
Technically only visible light can't reflect off it I believe.
@JWQweqOPDH 7 ай бұрын
It's not that visible light can't reflect off the object, it's that it won't carry the density of information we're looking for. The whole object would look like a single blur with no detail.
@konrad7592 6 ай бұрын
I wonder if there's a way of using some kind of micro shifting of the object to increase resolution - similar to some cameras or apps, that use device/sensor motion to increase the resolution, by multi exposure. @@JWQweqOPDH
@mleavitt787 7 ай бұрын
There are now more of the world’s smallest nerf guns in existence than there will ever be just regular nerf guns.
@RaethFennec 7 ай бұрын
Oh no. That's a great point!
@phasmos153 7 ай бұрын
legend
@logananderson9834 7 ай бұрын
Does that turn all the small ones regular size and the new ones now ‘giant’ size???
@tyjl3515 7 ай бұрын
@logananderson9834 I suppose technically, since the small ones are now closer to the average size of all nerf guns they would be considered normal.
@MarkRober 7 ай бұрын
🤯
@Decepticant 3 ай бұрын
In-freaking-sane! I can't express how important what you're doing is for the scientific community and the advancement of humanity. It's truly amazing.
@Alexis84DE 4 ай бұрын
I just want to say hats off and thank you to all the amazing students, researchers and professors ❤ what an inspiration for the future
@CincyKid1990 7 ай бұрын
Mark Rober is a storytelling genius. His ability to trick my kids into loving science, math and engineering is nothing short of a miracle.
@2OP4Scrubz 7 ай бұрын
Bruh he makes me love that, and Im 26 LMAO. Its so interesting!
@SSGoatanks 7 ай бұрын
We need new generations of scientists, math geniuses, and engineers; otherwise AI will just control everything!
@steeveedeee 7 ай бұрын
And salesman.. cough cough crunch labs
@joeychristensen1113 7 ай бұрын
Jokes on him. I was already interested before the channel started.
@Neros_Videos_2023 7 ай бұрын
Mark is the best!!!!! 👍👍👍👍
@TaiwanisMoving 7 ай бұрын
I think this is probably his best video yet. Every time I was amazed, he went even further. Each step was beyond what I thought was possible. That's a rare feeling to get as an adult, and it makes you feel young again. Thanks Mark
@necessaryduk360 7 ай бұрын
Mark liked ur comment
@ThatCanadianMinecafter 7 ай бұрын
I know, he made it so small.
@logananderson9834 7 ай бұрын
I completely agree!! I am passionate about learning and science so I tend to try and keep up on what ever is happening but there are industries where I don’t even know where to start! I was learning more about Crispr the other day and this was so fun to come across! Who knew you could form DNA into actual shapes! And I loved learning about the tiny useful machines! It was astonishing to me that he covered so much information in such little time all while making it impossibly easy to understand.
@user-sc3wt9pj2i 3 ай бұрын
こういうワクワクする実験が未来のエンジニアを生み出すんですよね！是非未来の為に活動を続けて下さい！. 1:40I absolutely love the edit/cinematography here. It's so seamless!.
@Annnabannanna 2 ай бұрын
Mark is actually incredible. Never thought I'd get so hooked into physics.
@fishdripfn 7 ай бұрын
Mark is the definition of quality over quantity
@thedictationofallah 7 ай бұрын
Hindu fascism is definition of quantity and mass hoarding over quality or rational logic
@Asher50 7 ай бұрын
@@thedictationofallah Bro HUMBLED him
@OQ0_2random 7 ай бұрын
so true
@thedictationofallah 7 ай бұрын
@@Asher50 who humbled me and i didnt humble anyone. i'm just sharing my thought what i think this comment relates to
@authorinthedark 7 ай бұрын
I dunno, he just made 3 trillion nerf guns that don't even work, definitely feels like quantity over quality to me
@ct5625 7 ай бұрын
This might be one of the best explanations of DNA manipulation I have ever seen. Well done just for that. Using the Nerf project as a vehicle to explain such complex science in a way that people can understand is extremely clever. Gives me hope for the future knowing there are absolute geniuses like Pallav and all his colleagues out there doing this kind of work.
@heejae2010 Ай бұрын
hello Mr. Mark Rober I am a second-year middle school student who is doing a homework activity for my ethics class. Thanks to Mark Rober's wonderful science videos, I have come to love science even more. Please make more great videos in the future! 😊😊😊
@tnfire614 Ай бұрын
I dont think Mark gets enough Credit for what he does. His work and dedication is close to Nobel worthiness.
@blissfullyignorant2852 Ай бұрын
He has millions of comments giving him credit for what he does. I'm not sure what you're talking about.
@blissfullyignorant2852 Ай бұрын
He actually gets more than is deserved, he takes credit for everyone else's work in the video.
@squibbelsmcjohnson Ай бұрын
Yahhhhh he gets his credit 😂
@MemeGod201 7 ай бұрын
Mark is the guy that will literally remake all of his childhood toys into something insane.
@thewhyguy069 7 ай бұрын
ture
@carrotnonumbershere 7 ай бұрын
lol true
@user-ff7mw2eq1d 7 ай бұрын
ur dum
@sameerislam1328 7 ай бұрын
I love it
@MonkeMan74 7 ай бұрын
mark be like " I enjoyed this a while ago, time to make it ridiculous"
@iikpsyt4619 7 ай бұрын
It’s crazy how a project like this could potentially change medicine in the future. I’m so excited to see what this DNA technology could bring.
@pallavkosuri5606 7 ай бұрын
We’re working on it!
@ThatCanadianMinecafter 7 ай бұрын
He hearted your comment
@Bubblewrap9YT 7 ай бұрын
Here before it blows up
@huiberthubertusi2561 7 ай бұрын
Same
@Caliginosi7y 7 ай бұрын
@@pallavkosuri5606I look forward to seeing Kosuri's and Rober’s names on the paper!
@anoichi4840 Ай бұрын
im not even into like mechanics and science and everything but all of a sudden im learning so much from this guy
@user-fu8nw1ur7r 4 ай бұрын
Sir your knowledge is amazing
@micahyang5614 7 ай бұрын
Absolute joy seeing Pallav Kosuri on this channel. We had the pleasure of hearing him give a talk at our university, his enthusiasm is contagious.
@qwertydavid8070 7 ай бұрын
Honestly I could listen to him ramble on for hours. Are there any videos out there of any lectures he's given?
@poluefemus 7 ай бұрын
you know you’re screwed when you’re fighting against a guy with not only the biggest nerf gun, but also the smallest nerf gun
@supersonic5024 7 ай бұрын
Nah you know youre screwed when he knows a guy that can build nerf guns with dna 😂
@poluefemus 7 ай бұрын
@@supersonic5024 you know you’re screwed when the guy can build over a trillion nerf guns out of you
@Lazy-Lizard 7 ай бұрын
@@poluefemusa trillion nerf guns out of a single drop of your blood*
@S.E.C-R 5 ай бұрын
How do you continue to keep blowing my mind even more than the last time?! 🤯🤯🤯
@AlbertoMavic3 2 ай бұрын
Me Exploto la cabeza con este documental. FELICIDADES, por hacer realidad una simple idea. Eres y sois los científicos un ejemplo para el mundo. Un saludo desde España.
@voicekey 7 ай бұрын
Ant was having the time of his life
@theinkblobcrown1889 7 ай бұрын
Do I know you from somewhere?
@huiberthubertusi2561 7 ай бұрын
Yes
@unkown3840 7 ай бұрын
no
@SportzSwag 7 ай бұрын
Here before this comment blows up
@ethanslife7851 7 ай бұрын
Indeed, ant force
@taylorguitar13 7 ай бұрын
So unreal... If there were videos like this being made when I was little, it would have probably inspired me to pursue engineering. I'm happy it's here for today's kids to see. Doubt you'll see this Mark, but if you do, just know I'm glad there are people like you out there. You're doing great work.
@spartanbeast3575 7 ай бұрын
I'm currently studying master's of science in mechanical engineering and Mark Rober as blown my mind away with this video.
@lindaatteo409 22 күн бұрын
Mind blowing to the next level. I’m so impressed with your knowledge and dedication to your craft it gives hope to solving problems
@dubbletrubble1549 3 күн бұрын
18:10 as someone who only took one year of Biotechnology in High School, THAT'S LITERALLY THE FIRST THING THEY TEACH YOU!
@Knarfy 6 ай бұрын
Wasn't expecting to learn how cool DNA is during a video about Nerf guns but I am so incredibly here for it.
@Wabee014 6 ай бұрын
What are you doing here ????
@blanekaboom 6 ай бұрын
i was surprised to see knarfy ngl
@Bfa10i 6 ай бұрын
HOW ARE YOU HERE! GET OVER HERE!
@finnedgaming9965 6 ай бұрын
get back to crashing minecraft 😤
@dna9838 6 ай бұрын
Thank you. I do my best.
@xtreme443 7 ай бұрын
As a recent graduate in the engineering field and 3D printing experience now working with semiconductors, this video has been one of the most interesting videos Mark has ever put out. I would love to work on something like this with Mark one day.
@empanadas2887 7 ай бұрын
.
@matthewb9981 7 ай бұрын
Bring that enthusiasm to your work and be the person that others want to work with!
@Noxuren1 Ай бұрын
I love how mark uses something to get us hooked in just to secretly make us smarter
@TheRealSavageMaestro 5 ай бұрын
Living science LEGEND. I love this guy!
@TheoHiggins 7 ай бұрын
In amongst all this incredible science and learning tools I'm beyond glad that Mark still uses Plants Vs. Zombies music lol
@quattuorvigintupletritrigi8357 7 ай бұрын
It’s epic music
@sterthebird1593 7 ай бұрын
bro I was about to say that exact same thing XD
@snoopy1915 7 ай бұрын
Same
@konrad7592 6 ай бұрын
what part?
@ChopSensei 6 ай бұрын
@@konrad75923:00
@poazon7 Ай бұрын
日本語の音声ありがとうございます！こんな素敵な動画が無料で楽しめることに感謝。
@DungTran_vietnam Ай бұрын
SSSniperWolf @SSSniperWolf 34,3 Tr người đăng kýSSSniperWolf @SSSniperWolf 34,3 Tr người đăng kýSSSniperWolf @SSSniperWolf 34,3 Tr người đăng kýSSSniperWolf @SSSniperWolf 34,3 Tr người đăng ký
@08C6PaceCar Ай бұрын
The collective mind and spirit of human beings together knows no bounds
@bobthemagicmoose 7 ай бұрын
I had the dorm room literally across the hall from that one a few years after you and we went through every rooms’ access panels! We actually did find an instruction manual on how to break into the rooms, I wonder if it was yours!!! I think we replaced the items that were interesting and trashed the rest (of course adding our own treasures for the next generation)!
@Necrozatus 7 ай бұрын
I see
@venusrhodes7475 7 ай бұрын
Cool
@Mkitty888 7 ай бұрын
Whoa! That’s epic!
@mr.explosife3958 7 ай бұрын
lmao
@felixhenson9926 7 ай бұрын
Haha that's so funny!
@trissebude2184 7 ай бұрын
"We found a dead ant outside"... Minutes before that: "The ant was not intimidated at all! It even took our gun!" We see what you did there, Mark!
@MischiefL0ki 7 ай бұрын
lol
@meredithbutikofer5658 4 ай бұрын
8:15 “it was the smell more than anything that really brought back the nostalgia” This has a reason. That reason is, the processing center for smells in the brain lives extremely close to the memory center of the brain. This makes it so that the electrical signals to trigger remembering can take a shortcut from the smell processing center to the memory center.
@tarikhulmahfudz7829 2 ай бұрын
That 100nm was insanely small, i can't imagine how tiny 5nm processor is.
@District4Studios 7 ай бұрын
These videos are the highlight of the month whenever Mark releases them. They're entertaining, educating, and so exciting to watch. Thank you Mark, for these wonderful videos
@ThatCanadianMinecafter 7 ай бұрын
I know!
@carla.n.5078 7 ай бұрын
As an engineer, watching this is like seeing art being created.
@Some1NamedPlays 7 ай бұрын
As a regular person who isn't an engineer, I too, can confirm that watching this was like seeing art being created.
@user-ep7lm5sr8r 2 ай бұрын
DNAを使った形の設計すげえ！！！ タンパク質設計の前段階みたいでワクワクする
@TIOLIOfficial Ай бұрын
8:28 - Questionable Mark Rober lore.
@BobTheLegoMan511 Ай бұрын
Ye lol
@sevenayashinedown1283 7 ай бұрын
If they are considered nerf guns, I believe that Mark is now the owner of the largest collection of nerf guns, assuming he got to keep the little ones.
@bobbobert9379 6 ай бұрын
The size of a collection, for world record purposes, is typically determined by the number of *unique* items. Many copies of the same item wouldn't contribute to the size of the collection.
@9BallBory 6 ай бұрын
@@bobbobert9379collecting the same item is still a collection
@bobbobert9379 6 ай бұрын
@@9BallBory not by official world records standards it isn't.
@thegreatesthitman 6 ай бұрын
@@bobbobert9379but not every one is the exact same some have different shapes if you look closely so he does have the largest collection of nerf guns
@9BallBory 6 ай бұрын
@@bobbobert9379 mind showing me these standards? i dont care at all but where would you even find them lmao
@adarshjoseph3 7 ай бұрын
Thank you Mark! You filled us with hope about the future. It's really inspiring that so many great scientists around the world are working tirelessly for a better future. Thank you so much for showing us that!
@handlingitwell 7 ай бұрын
u sure that this video relates to a better future?
@user-nb7df 7 ай бұрын
He is literally proving to you that nanoweapons exist lol
@scrubdaddy654 7 ай бұрын
you didnt even watch the video its only been out 1 hour you comments 54 mins ago lol
@ThatCanadianMinecafter 7 ай бұрын
Yes
@tormint5294 7 ай бұрын
@@handlingitwellmedically maybe
@thebl4z3r66 5 ай бұрын
Bro literally took 'world record' and 'competition' to whole other level.
@CandyLover-sv8br 2 ай бұрын
Hey Mark Rober I know you probably won't see this but if you do I just wanna say thank you your the reason why I wake up in the morning so I can become a great engineer like you and help millions around the world like you as i said before thank you because any time I'm sad I watch one of your videos and it just cheers me up so thank you again.
@anwarulbashirshuaib5673 7 ай бұрын
1:53 What a heartwarming display of affection between student and teacher! Mark hugging his professor so enthusiastically really shows the wonderful bond they share!
@astro7484 7 ай бұрын
One lockdown 3AM night couple years ago I stumbled across a video of a dude playing with squirrels in his backyard I enjoyed it so much and decided to watch more, since then I have bookmarked and saved each and every one of these, they went from being just entertainment to fully immersive learning experiences. This is the kind of thing I want to do with my life. Currently a junior engineering students and these videos are really fuel for the work. One day ...🙏🏽🙏🏽
@solokom 6 ай бұрын
Same brother, same!. ... well, the squirrel video part, not the becoming an engineer part. 😁
@ilturcocinque1003 2 ай бұрын
One of the best video ever❤ i can see a little bit of hope in the world now, thank you all ❤
@ankhels 4 ай бұрын
I absolutely love this. Mark's a teacher, and a great one. We're actually getting a course in physics and engineering, not watching a random entertaining build video. THAT SAID... If we're going to be specific, everything past the 2nd shrink can't technically be called a nerf (or any) gun, because as he specifically says at 12:21, those and all of the ones after it are just outlines/molds in the shape of a gun. They don't have any of the actual parts, mechanics, mechanisms, etc, and are 100% inoperable. That's no longer a world record-breaking item. The first and then second shrinks did make the records, yes, but all the ones that came after (i.e. the two hair ones and the DNA one) are not, because they're not nerf guns. I'm sure they're the world record for SOMETHING, just not this. Still, amazing video either way. The accomplishments here are incredible nonetheless. And most importantly, every one of us has now learned something (or really a lot of things) new & were exposed to some brilliant scientists many of us had not heard of before. I absolutely love the vid though and the idea. Watching that tiny, tiiiny gun be fired under a dang microscope because it was that small was soooo cool! It's hard to believe things can even function at such a small scale!
@solokom 6 ай бұрын
He didn't only build the world's smallest Nerf gun, but he also built more Nerf guns than Nerf ever produced or will ever produce. 😱
@kitkat47chrysalis95 6 ай бұрын
i dont often literally laugh out loud but this comment got me
@dion4037 6 ай бұрын
Oh wow dude that's an awesome point lol
@alexcole8930 6 ай бұрын
Bro has 2000iq
@IndigoIndustrial 6 ай бұрын
He loaded and cocked all the DNA nerf guns with a flash of blue light. A slight tap of the test tube on the lab bench discharged them all - and leveled the Salk Insitute.
@gabrielshreds 6 ай бұрын
until Mr Beast builds one out of quarks
@914Rocky 7 ай бұрын
Mind blown. Most amazing thing you’ve done too date. I’d love more detail on how the DNA was self building.
@ESOInTeNsE 7 ай бұрын
A lot of work with DNA is done using chance. Notice how they had to use electrophoresis to separate out the bits of DNA that didn’t form nerf guns. It’s because they knew that if they put in the proper structures and let the DNA bind to itself as they knew it would, that chances of it creating nerf guns was pretty high, but chances are there were a LOT more of the failed pieces that didn’t bind correctly, which they separated out.
@volmyk6196 7 ай бұрын
DNA is a polymer and each single strand of DNA is a sequence of monomers called nucleotides that come in 4 major types: A, T, C, G. When two DNA strands come together to form a double-stranded form, they normally must follow the rule of complementary: A must be opposite to T, and C to G. In DNA origami, each staple DNA sequence is typically long enough to be close to a unique sequence inside the test tube, therefore it is designed to be complementary to specific counterparts in the scaffold DNA. If two complementary DNA strands are placed in solution, they spontaneously would bind into the double-stranded form, reasons for that arise from the laws of thermodynamics. Here, given enough time and preferably a temperature ramp, the staples will eventually "find" their complementary places in the scaffold. The whole process is governed by DNA self-assembly properties, there are CAD tools that can generate the sequences for staples based on your scaffold sequence and the design of DNA origami nanostructure you make. Then its just mixing scaffold and staples
@914Rocky 7 ай бұрын
@@volmyk6196 Thanks! How do they keep all of the strands near enough to their complementary strands to bind? With so many in use, wouldn’t they get jumbled up? Is it that each piece in each gun is unique so that they will each find their unique compliment? How do they make each strand?
@Infamous159 7 ай бұрын
from one scientist to another, thanks for explaining in simple terms. @@volmyk6196
@benjaminerickson9732 7 ай бұрын
That part is helped by the temperature they are incubated at in the little "oven". The pairing up of those nucleotide sequences have different energy requirements, heating up paired up DNA is how we normally unzip the strands and get single stranded DNA. You start off at this high temp where nothing can pair up, then you cool it down and hold it at ideal temps that favor particular sequence pairings. In this way you can help direct the assembly of the finale product. As annealing temperatures are easily calculated and used all the time in DNA amplification.
@Crazyproaoe Ай бұрын
-ну что потомки, как вы там в 2024? Покоряете космос, вышли в 4ое измерение, летаете со скоростью света? -сегодня мы собрали микроскопический пистолет из которого застрелили муравья.
@SpectrumSwordtails 5 ай бұрын
Mark Rober ladies and gents. He not only got the record for the worlds smallest Nerf Gun, he may have also given some dna engineers some new ideas. Love it.
@OfficiallySnek 7 ай бұрын
Bro actually made a DNA gun 💀
@patford9943 7 ай бұрын
Mark, you and your team outdid yourselves! Thanks for mentioning the names of the students and staff not just dept heads. It’s great to see the credit get spread around
@Nickskeeee Ай бұрын
This was so amazing! I have so much hope for science to bring a better future, especially in the medical world. My mother and I are Multiple Sclerosis patients and I've already seen some news about new technologies on how to treat it better... But by seeing this video, by seeing how some of these techniques can be used in the medical field. I have even more hope for science! Science is amazing!
@voltmaster5005 11 сағат бұрын
Ok so not only did you make the smallest nerf gun you actually made the smallest functioning gun in history
@inigoaraluce8493 7 ай бұрын
I'm pretty sure Mark's channel is the only channel that produces such incredibly interesting content for every single age. Incredible video!
@jwhite1016aol 7 ай бұрын
Not 1 year olds
@S_29 7 ай бұрын
Not 2 year olds
@starmanofspacetime9825 7 ай бұрын
Not 3 year olds
@Recklessneo 7 ай бұрын
Not the sperm that just gotten to the egg
@JPmax4ever 7 ай бұрын
Maybe 4 year-olds
@ThePropzman 7 ай бұрын
"Brush off the unused Uranium"💀 8:48
@AGamingDemon5810 Ай бұрын
I don't know why but this video is probably my favorite video on KZfaq now.
@ismaelcarvalho4449 4 ай бұрын
Mano, esse canal é muito bom! parabéns
@sagerobot 7 ай бұрын
Mark you're a treasure to humanity. Seriously, thank you for doing what you do. Ive been feeling dejected lately over the online discourse talking about how the public school teachers are reporting their students being very behind and lacking motivation to want to engage at all. But your content I truly believe is the spark that absolutely will be the start of so many kids today becoming adults in the future who pursue STEM for the betterment of mankind. Your content is the exact kind of content that we should be celebrating as a society. You can tell that you truly care for this world and you want to do what you can to encourage and inspire people around you. I hope you continue to keep doing what you are doing, it is truly a great service to the world.
@YouTube 7 ай бұрын
wow heading back to your alma mater for this video must have been such a wholesome feeling 🥲 you've come so far!
@Colonel__Mustard 7 ай бұрын
Could you fix the language settings on this video? I know you're the media person, but I can't get it to be in english while casting in on my TV. It's not a user problem, trust me. Also, any way to force the app to play video in their ORIGINAL language?
@Pear341 7 ай бұрын
youtube do you realize that if someone post a coment and like their own comment and reply the coment 3 times the comment will be tecnicaly more important than your comment?
@Pear341 7 ай бұрын
Welp not anymore
@empanadas2887 7 ай бұрын
hi yt 👾
@Iveraxi 7 ай бұрын
what youtube
@brianbarnes4243 4 ай бұрын
amazing i truly enjoy everything you do your literally the millennial version of bill nye! your videos should be in every classroom thanks for shedding light on the amazing scientist who have done amazing things for the world! Scientist are our only hope for the future
@suneettembare9681 Ай бұрын
Oh! Awesome! I wish I had access to such content at my school days!!!
@alexfray6519 7 ай бұрын
As an engineering student at BYU, this was so fun to watch. Definitely an inspiration when the classes are hard!
@OkGamez313 7 ай бұрын
BYUI IS BETTER!!!
@jacquesca 7 ай бұрын
Is the engineering school there just for mormons? And/or is it a leading uni for engineering?
@Kavaitsu 7 ай бұрын
@@jacquesca 💀
@ryanpmcguire 7 ай бұрын
@@jacquescatechnically no but you’d better be prepared!
@jdawggy8761 7 ай бұрын
@@jacquescait’s definitely not just for lds people, most people there are but everyone is welcome
@veerbakhalakiya4410 7 ай бұрын
I used to be a fan of Mark Rober, but after watching this incredible video, I am a whole air conditioner.
@consuelorodriguez2695 7 ай бұрын
😂
@GoldenAwe228 7 ай бұрын
lmao
@Hiddenreader 7 ай бұрын
I had to read that twice to get it 😂
@_littleRock_ 7 ай бұрын
😆
@Warrior_Cats_Spottedleaf 7 ай бұрын
😂😂😂😂😂😂😂😂😂😂😂😂😂
@user-jx1he6he7v 2 ай бұрын
This is one of the coolest videos I've seen all day.
@randomhistorystuff165 5 ай бұрын
He went here a month before my little brother went on a field trip to BYU! We love that you love our city of Provo!
@thomassullivan4679 7 ай бұрын
Mark, Lately as an engineer and a teacher I feel kind of low about what we are doing and where we are going as a people. Then I watched this video and I have come away feeling hopeful. Thank you! This was very cool.
@jenkins5265 7 ай бұрын
Same! Whenever I'm feeling pessimistic about the world, I come to watch Mark's videos to remind myself that heroes don't always have the loudest microphones. There are people like Mark doing incredible work everyday.
@DanTr90 7 ай бұрын
It's because of 76 million people, in the USA at least, that are trying to roll us back to the stone age.
@sherilynl4038 7 ай бұрын
@@jenkins5265 yep, ...those denouncing science and such gets depressing then i see this
@JustinSugita 7 ай бұрын
I love how Mark helps share what is the bleeding edge of the new science, but putting them together in a fun format and interesting projects. When you think its an impossible idea, there is someone out there that is able to help with this.
@N1Alf 3 күн бұрын
Felicidades por tu trabajo. No solo entretiene, sino que transmite enseñanza y hacen divertida a la ciencia. Estoy seguro de que más de una persona ahora está más motivada a investigar un poco más.
@nateschale189 4 ай бұрын
I actually watched this channel for scientific stuff that I don't learn in school and it's Christmas break. So I have to watch many Mark Rover videos I want
@mpoindex1 7 ай бұрын
As someone who has worked in a DNA origami lab and sat at a computer for countless hours designing staples (just to build a rectangle mind you), thanks for highlighting this technology. It’s pretty cool stuff!
@Hobby_Technology 6 ай бұрын
This video had me wondering, and I'm hoping that you might be able to provide some insight here, how are the staples actually made? Design aside (I would still love to learn about the design) but physically, once you know which bases belong in the staple, what tools are used to actually construct the staple?
@WillyOrca 5 ай бұрын
Every single time they made it smaller I was like "well this is it they can't possibly get any smaller than that." and by the end I was just totally in awe.
@user-ez2tq4vi8f Ай бұрын
normally such a scenario would make you progressively more disappointed
@R4ndomUser567 3 ай бұрын
I got a DNA test. Turns out I'm 0.02% nerf
@enderbrine_7778 3 ай бұрын
WOW!!! This is amazing!
@kristine146 7 ай бұрын
Jocelyn, you are the real MVP. Spoken like a true scientist "although there is no label on it." Put a label on your stuff. When in doubt, throw it out. That is the motto of my lab. 18:09
@tycowpie 7 ай бұрын
@18:48 da REAL MVP
@Jark6 7 ай бұрын
@@tycowpie only time i paused the vid.. GYATT
@Daedricsoulslayer 7 ай бұрын
@@tycowpiesame mate same! 🥵
@Fajowski50 7 ай бұрын
Jocelyn has the entire bakery.
@mangotreebs7749 7 ай бұрын
2:25 That looks like a mugshot💀💀💀💀💀💀
@williamhulse6370 7 ай бұрын
So true 😭
@ProcentNinja 6 ай бұрын
Mark rober jail card 💀
@R4ndomUser567 3 ай бұрын
Especially with the orange shirt 💀
@AlexsaysBruh 17 күн бұрын
He looks like an angry bird
@cyberbreakers.esports Ай бұрын
Eu vejo os videos desse cara, mais pela forma que ele explica do que pelo conteúdo, faz deixar tudo interessante
@roxroblox9269 2 ай бұрын
this guy is crazy, keep up the work :)
@briansmobile1 7 ай бұрын
14:23 "Would you patent the Sun?" Dr. Jonas Salk... one of my idols too!
@luis38265 7 ай бұрын
🗿
@aditip6695 7 ай бұрын
@@luis38265🗿
@matthewboire6843 6 ай бұрын
@@aditip6695🗿
@shark9488 7 ай бұрын
its crazy how far mark has come. 8 years ago, he was showing us how to make a watermelon smoothie and now he is breaking 4 records in one video!
@kongsunlyheng4186 7 ай бұрын
I think it's even more amazing that an idea of a toy unexpectedly can be a potential solution to a complicated problem at the end.
@user-ft1qo7yq6w Ай бұрын
This’s the passion of science, this is what science all about.
@Hectorxpi 3 ай бұрын
19:20 Mrbeast: today I'm going to make a nerf gun with atoms
@VicJang 7 ай бұрын
Another incredibly well made video. Thank you so much Mark for being an absolute inspiration for millions of people. I’ve had so much fun watching your videos in the last several years, and now my 9yo son is following the steps and is developing a more and more engineering mindset everyday. Thank you truly.
@isthatatesla7191 7 ай бұрын
Thanks for putting your two cents in on our behalf. I mean, two dollars. Almost.
@KraZSK 6 ай бұрын
It's always just so marvelous to see people like Mark still geek out like a kid with conviction in an incredibly complex adult field...
@Planetmango48 6 ай бұрын
Yeah.
@Koilith 6 ай бұрын
“Umm guys I think I’m better than mark Rober” -🤓
@Pspoyun. 6 ай бұрын
Selam
@user-ve7ji8zb8v 6 ай бұрын
He’s so hot! Smart, enthusiastic, optimistic, passionate, fun-loving, and so down to earth.
@Khanhblack07 6 ай бұрын
Yeah Mark thanks very much ❤❤❤❤
@RollTide24-7 Ай бұрын
Respect to BYU!
@williamroberts364 4 ай бұрын
😦... i can't belive this channel exist, this video inspire me in a several moments, and its all productive and usefull and beautiful!!
@WaterjetChannel 7 ай бұрын
This was like those 3D rendering videos that show scale of how big/small things are but it was 3D printing. This technology is mind boggling. Also I live in Provo lol
@ikocheratcr 7 ай бұрын
Just imagine a water jet cut one :)
@somebody3271 7 ай бұрын
If only the DNA gun would work lol
@davidandrews5262 7 ай бұрын
@somebody3271 what are they really doing at that lab with DNA? Lol probably medicine. But the anime nerd in me imagines they are creating new lifeforms lol
@Iuckycigarette 7 ай бұрын
You gotta make a video of a waterjet cut one
@ThisGuyDannyyy 7 ай бұрын
First
@Cereal_Fish 7 ай бұрын
13:04 found a dead ant "outside"
@cringekiddo 6 ай бұрын
“Found”
@hexboxx735 27 күн бұрын
This is my favorite mark rober video by far.
@kattozilla2277 Ай бұрын
this video fills me with joy
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