Рет қаралды 48,111
Cancer is a spooky demon. It's the inevitable accumulation of mutations within our genome yet... why does it happen at all?
Big thanks to William Norberg for making the custom intro, thumbnail, and some assets for me! Check out his art here: blenderfoto
Acknowledgements:
-Brady Johnson's method for DNA model - kzfaq.info/get/bejne/o52Sh6hyp9WlqqM.html
-CVallance Cell model I used - skfb.ly/JnBC
Sources/Further Reading:
Carcinogens and DNA damage - dx.doi.org/10.1042%2FBST20180519
TP53: a key gene in human cancer - doi.org/10.1016/S0300-9084(01)01356-6
Somatic Mutations - doi.org/10.13070/mm.en.8.2673
Tumor-Suppressor Functions of the TP53 Pathway - dx.doi.org/10.1101%2Fcshperspect.a026062
DNA Replication and Causes of Mutation - www.nature.com/scitable/topicpage/dna-replication-and-causes-of-mutation-409/
Human Chromosome Translocations and Cancer - www.nature.com/scitable/topicpage/human-chromosome-translocations-and-cancer-23487/ -