I love Ursula Le Guin!!!!!!!

He lost me when he bashed Trump.

Great man👽👽👽🛸🛸🛸🇬🇷🇬🇷🇬🇷

Beat kuşağının en önemli şairi olduğu gibi Kerouac , Ginsberg, Ferlingetti ve Miller 'i tanımış ve o yıllarda yaşamış bir sanat insanı.. Bir Beat Zen yolcusu. Günümüzde pek tanınmasa da bilenler biliyor...

And today on 24 May 2024, the iron curtain around Gaza has not worked. A wall never worked never works never will work. King Canut comes to mind. Global Heating Climate Emergency can be stopped by a wall also? What a sad species sapiens is.....

Zionism began in the 1880s. In 2024 Zionism is finally and deservedly dying, but as Nazism and fascism are always with us, so will zionism remain. Sapiens are a species that contains the gamut of behavior from best behavior to worst. Evolution is slow but a failed species is soon extinct. Love life while we/you have it?

As a BA and UX designer with five years experience I find that you can't just have the business objectives in mind and neglect the value and experience that the users would get from any initiative, project or product. When you understand who you are building for it makes it easier to achieve the business objectives.

15 years later still a gold mine💯👏🏿

One of the best crystal clear lectures from Prof. Kane

هي جُمَلَةٌ إسميَّةٌ، لا فِعْلَ فيها أو لها: للبحر رائحةُ الأَسِرَّةِ بعد فِعْلِ الحُبِّ... عطرٌ مالحٌ أَو حامضٌ. هِيَ جملة إسميَّة: فرحي جريحٌ كالغروب على شبابيك الغريبِة. زهرتي خضراءُ كالعنقاء. قلبي فائضٌ عن حاجتي, متردِّدٌ ما بين بابَيْنَ : آلدخولُ هو الفُكَاهَةُ، والخروج هُوَ المَتَاهَةُ. أَين ظلِّي - مرشدي وسط الزحام على الطريق إلى القيامة؟ ليتني حَجَرٌ قديمٌ داكنُ اللونيْن في سور المدينة، كستنائيُّ وأَسودُ, طاعِنٌ في اللاشعور تجاه زوَّاري وتأويل الظلال. وليت للفعل المُضَارِع موطئاً للسير خلفي أو أمامي، حافيَ القدمين. أين طريقيَ الثاني إلى دَرَج المدى؟ أَين السُّدَى؟ أَين الطريقُ إلي الطريق؟ وأين نَحْنُ, السائرين علي خُطَى الفعل المضارع, أين نحن؟ كلامُنا خَبَرٌ ومُبْتَدأٌ أمام البحر, والزَّبدُ المراوغُ في الكلام هو النقاطُ علي الحروف, فليت للفعل المضارع موطئاً فوق الرصيف ... Above is its Lyrics. Below is its google translation It is a nominal sentence, not a verb In it or for it: The sea has the smell of beds After making love... a salty perfume or sour. It is a nominal phrase: my joy Wounded like the sunset on your strange windows. My flower is green like a phoenix. My heart is overflowing About my need, hesitating between two doors: Entry is humor, exit is the maze. Where is my shadow - my guide is in the middle Hustle on the road to resurrection? Wish An old, dark-coloured stone in the city wall, Maroon and black, stabbing into the unconscious Towards my visitors and the interpretation of shadows. I wish The present tense verb has a foothold to walk behind me Or in front of me, barefoot. where My second path to the range ladder? where The warp? Where is the way to the road? And where are we, walking in the footsteps of action? Present tense, where are we? Our words are news And a beginning in front of the sea, and the elusive foam In speech, it is the dots on the letters. Let the present tense verb have a foothold above Sidewalk ...

At 3:59 you say F maps x to a unique value. That is not correct. It maps it to a definite value; not a unique value, but a definite value.

Edward Said is a Protestant Christian. He stood against the evangelical myth that Palestine is the land of the Jews, and he defended the rights of his people in American universities. He was AIPAC’s nightmare.

In sharing his brother's resistance to "population policy", what his brother said to the official includes that "if you go xxx the children in Hong Kong, I will. . . " -- I think this part was missing from the translation.

我听到三十多分钟处阎连科分享哥哥是最值得最尊敬的人。我也这么觉得。👍

Competition????? Oh boy......................... different interviewer please!!🙄

Little Knowledge in English, little knowledge in Japnanese, and low IQ create big mistakes, and high misunderstanding

THIS OLD WOMAN IS THE WORST translator I have ever listened. . Firstly, she is too idiot to understand what Miyazaki was saying . Every of his words has meanings BUT THIS old woman did not have enough knowledge to know what he tried to express. And she said in the quite different things . She said what he did not say .

THIS　OLD　WOMAN　MADE　 LOTS OF MISTAKESSSSSSSS。　　IDIOTSSSSSSSS OLD　WOMAN

このおばさんの翻訳はほぼ真t違ってます　最低

"There are millions of them" wow!

A great American. Thank you, Dr. Fauci.

it sounds like they dont know what they doing

But, does this "firing after failure" not lead to sticking to textbook solutions and not to trying something new and possibly better?

Gary: The Father of the Back to the Land ecology movement of the 60’s and 70’s and the major reason that kids then and even now wear backpacks. The Rucksack Revolution come to fruition.

Oh gosh. This blew my mind.

13:37 ... the CIA's original "charter" in 1948 had nothing to do with committing crimes against gov'ts in other parts of the world. so he has that wrong right out of the gate. it evolved into that over time but it was not Truman's original intention. Truman denounced the CIA and what it had become after JFK was murdered. Allen Dulles went to see Truman after Truman had written his article and tried to get him to recant what he had written but he would not.

I respect your mom!

Tony Blair is clearly a man of many talents...

1:53:53

1:07:44

it's paternal age

The bird on the chest could more so be an ancient long tail or a Scott Reid Auf

He tried to put evolution in a neat way to reconcile science and the Bible. But he doesn’t need too. Evolution theory says about the leaps in the process that he mentioned as “ the gap”. This gives room to God. As long as evolutionists can’t explain what happened in the Leaps, please stop trying to put God in your evolution box. He is so arrogant thinking that his genetics knowledge can explain God. I wish we can explain God that way but we can’t. Dr Collins should be repent.

Tell me why TM is only taught in exchange for money. Why isn't it free, if it's so amazing for human beings and the betterment of humanity?

21:42 sus

Fantastic lecture, thank you!

16 years and nothing has changed. The crimes of Israel have only gotten more grotesque. Part of me is glad Said is no longer with us to see the current carnage in Gaza.

AUSTRALIANS DONT WANT NUCLEAR POWERED AUKUS SUBMARINES THIS IS JUST A WAY ISRAELI ROTHSCHILDS CAN PUT AUSTRALIANS FURTHER IN DEBT AND SNEAK IN NUCLEAR POWER VIA THE IDIOT OPPOSITION LIBERAL PARTY LEADER PETER DUTTON WHO WORKS FOR ISRAELI LOBBY GROUPS SENATOR CYNTHIA MCKINNEY TALKED ABOUT. KENNEDY STARTED TO WITHDRAW USA TROUPS FROM INDO CHINA IN 1963 AND THEB KENNEDY WAS ASSASINATED 1963 PRESUMABLY BY CIA PRESIDENT H W BUSH SKULL AND BONES WHO PUT IN PRESIDENT LBJ WHO CONTINUED VIETNAM WAR FOR ANOTHER 10 YEARS BOMBING VIETNAM LAOS CAMBODIA INTO KILLING FIELDS AND COMMUNIST STATES WHICH THE CIA THEN CONTROLED BY POST WW2 GOLDEN TRIANGLE VIETNAM THAILAND BURMA CHINESE OPIUM WARLORDS WHO INHABIT HIMALAYAN MOUNTAINS FROM AFGANISTAN TO BURMA LAOS THAI HILLTRIBES WHO GROW OPIUM TRADITIONALY FOR LOCAL USE AS A SMOKED NOT INJECTED RAW OPIUM SOCIAL LUBRICANT AND CASH CROP WHICH PROF PETER DALE SCOTT SAID SHOULD BE LEGAL. THE SAME ARGUENTS APPLY TO CANABIS EXCEPT CANABIS USE ALSO HAS HINDU AND JAMACAN RASTA SPIRITUAL PATH ASPECTS AND LINGUISTIC SIGNIFICANCE S AS RASTA USE A SEED SYLABLE OF MANTRA = PROTO INDO EUROPEAN SANSKRIT FORMALISED CREOL OF PALI=LOTUS PEOPLES LANGUAGE SHAKYA MUNI SPOKE 500BC THAT PERVADS MOST OF THE WORLDS WESTERN STYLE DEMOCRACIES ANCESTORAL ROOTS. IN THIS CREOL RA ASTA MEANS SUN STAR BEING , SVA=SU=MILK ASTI=BEING KA=EMBODIMENT SVASTIKA THE NAZI SYMBOL IS A HINDU BUDDHISIT PHILOSOPHICAL KOEN MEANING MILK BEING EMBODIMENT OR BODHI=ENLIGHTENING CITTA=MIND AND REPRESENTS A STAR NEBULA GIVING RISE TO CELESTIAL BODIES VIA BIRKLAND COIL OF THE ELECTRIC UNIVERS "THUNDERBOLTS OF THE GODS" MOVIES EXPLIAN WELL. SO THE DEPTH OF MIND CONTRO BY ACADEMIA HOLLEYWOOD AND SKY FOX NEWS ISRAELI MOSSAD MEDIA IS PHENOMENAL EINSTIEN CLOWNS ASSERT THIS IS A SINGLE MASS UNIVERSE IN WHICH GRAVITY IS THEREFORE NOT A MEASURABLE FORCE. I DONT KNOW WHAT FORCE ACADEMIC EINSTIEN CLOWNS THINK STRECHES THE SPRING ON A SCALE WIEGHING UP FRIUT AT THE SUPERMARKET BUT EINTIEN CLOWNS ASSERT THIS IS AN EFFECT OF A BLACK HOLES INFINITE MASS IN A SINGLE MASS UNIVERSE BENDING THE FABRIC OF TIME AND SPACE. CLEARLY ISREALI ROTHSCHILDS ZIONIST ACADEMICS SPEAK A LOT OF GOBELDY GOOK. 'THE AMERICAN WAR MACHINE" PROFESSOR PETER DALE SCOTT SAYS IS RELATED TO DRUG FINANCE CIA TERRORISM SIMILAR TO NAZI RIECHSTAG BOMBING PRIOR TO WW2, THE DEEP STATE CIA MI6 MOSSAD ASIO DO ACTS OF FALSE FLAG TERROR SPUN BY SKY FOX MURDOCH ISRAELI MOSSAD MEDIA WHICH CAN CAUSE WW3 IRAN IREALI NUCLEAR WAR, IN 1885 QUEEN VICTORIA ELEVATED NATHAN DE ROTHSCHILD TO THE HOUSE OF LORDS WHILST ROTHSCHILDS ZIONIST AGENT DISRAELI ,A SEMITE PRETENDING TO BE ANGLICAN CHRISTIAN WAS PRIME MINISTER, THESE ARE UK LORD PALMERSTONS ZOO BEAST FREEMASONIC LODGES CRATED 1843 LIKE BNAI BRITH YOUNG ISRAEL WHO VIA LORD PALMERSTON WERE ALSO CHINESE OPIUM WARLORDS BACKERS AND VIA UK LORD BALFOUR DECLARATION TO LORD ROTHSCHILD THESE UK LORD PALMERSTON ZOO BEAST FREEMASONS CREATED ASKA-NAZI YIDDISH GERMAN POLISH SLAVIC COMMUNISTIC AND CORPORATE FASCIST BASICALY NA-ZI SETTLENTS IN PALESTINE 1917 WHICH POST WW2 EXPANDED TO BECOME THE STATE OF ISRAEL WHICH HAVE GONE ON TO BANKRUPT THE SECULAR WESTERN STYLE DEMOCRATIC WORLD VIA ISRAELI LOBBY GROUPS WHO CONTROL BOTH SIDES OF PARLIAMENT LEFT AND RIGHT. USA SENATOR CYNTHIA MCKINNEY EXPOSED THIS ISRAELI LOBBY AFFECTS ALL WESTERN SYTLE DEMOCRACY. USA IS VOTING TO SEND ANOTHER 95 BILLION TO WASTE IN UKRIAN WAR AGAINST RUSSIA HOW MANY 100S OF BILLIONS OF DOLLARS DO USA TAXPAYERS WASTE ON ISRAEL WAR ON PALESTINE SYRIA LEBANON AND IRAN/IRAQ PERSIA WHILST USA AND ITS ALLIES IN AUKUS COMMONWEALTH CIVIL SOCIETY FALLS APART. MURDOCH SKY FOX NEWS AND CNN IS ISRAEI ROTHSCHILDS NAZI/ZIONIST PROPAGANDA AS IS NEW YORK TIMES.THEY ARE ALL1843 CREATED UK LORD PALMERSTONS ZOO BEAST VENETIAN PARTY BLACK NOBILITY FREEMASONIC LODGES WHO MOVED NORTH INTO EUROPE FROM VENICE DURING CRUSADES TO JERUSALEM LODGES LIKE BNAI BRITH YOUNG ISRAEL, YOUNG TURKS, YOUNG AMERICAN KU KLUX KLAN & MORE RECENT WEF YOUNG GLOBAL LEADERSHIP SCHOOL ARE POST WW2 NAZI ZIONISTS WHOS SYMBOLS ARE AT DENVER AIRPORT. CERN IS AN EMP DEW AND IS CONTINUING WW2 NAZI BELL PROJECT PROBABLY INTENDING TO SHIFT NORTH POLAR AXIS AROUND 30 KILOMETERS A YEAR TO UPSET WEATHER OR ALTER EARTHS MAGNETASPHERE IN SOME WAY. AI IS OFTEN JUST A BUNCH OF INDIANS PRETENDING TO BE ARTIFICAL INELLIGENCE THAT IS ALSO USED TO KILL PALESTINIANS IN GAZA STRIP. AND AMAZON AI 'JUST WALK OUT" IS AN EXAMPLE OF NAZI/INDIAN AUTOMATON AI.. GOTTHARD BASE TUNNEL OPENING CEREMONY LOOKS LIKE HEBREW 1933 GERMAN NATIONALIST HITLERS GROUPS AND ROTHSCHILDS NATIONALIST-ZIONIS=NAZI ALLIED GOVT , NAZI DENVER AIRPORT END TIMES ZIONIST OCCULT. OTHER POST WW2 NAZIES IN UKRAIN HAVE A ROOT RACE THEORY THAT IS DEFINITLY EVIDENT IN UKRIAN ASOV BRIGADE "RIECH OF THE BLACK SUN" "WOLFANGEL" AND "SWASTIKA" SYMBOL USING NEO NAZI WHITE SUPREMACIST SEMITE OCCULT BACKED BY SPLINTER GROUPS FROM THEOSOPHY IN USA LIKE ANNIE BASANT AND STIENER , VENETIAN PRINTING PRESSES OF JESUITS PRINTED LUTHERS PROTESTANT BOOKS BUT ALSO INSPIRED ANNABAPTISTS SIEGE AT MUNSTER GERMANY THESE SAME BAPISTS KU KLUX KLAN SKULL AND BONES ARE CONFEDEREATE SLAVERS AND NAZI COLLABORATING FAMILIES OF WW2. THESE NAZI OCCULT THEORY OF ROOT RACES USES ROSECRUTION SYMBOL THE DOUBLE TRIANGLE ISRAELI FLAG NAZI DOUBLE TRIANGLE SYMBOL WITHIN AN ORB WITH A CHRISTIAN CROSS ABOVE IT. "THE VIDEO THAT LED TO THE ARREST OF BRENDON OCONNELL BY AUSTRALIAN ZOG" SAYS IT ALL ,ISRAELI ZIONISTS HAVE TAKEN OVER AUSTRALAI AND JAILED OCONNELL FOR SPEAKING OUT. THE CURE FOR WHAT RICHARD DAWKINS CALLED "THE GOD DELUSION" IS DARWINISM ISRAEL WILL VIA TRUMPS "SPACE FORCE" WEAPONISE SPACE AND USA MAY BECOME A VICTUM OF ISRAELI EMP DEW POWERED BY NUKES WHICH WILL TAKE DOWN USA VIA EMP DEW DESTROYING USA POWER GRIDS (SEE DENIS QUAID, GRID DOWN MOVIE) AND POWER GRIDS IN AUSTRALIA CANADA AND UK COMMONWEALTH NATIONS ARE THREATENED BY ISREALI NUCLEAR POWERED EMP DEW ATOMIC EXPLOSIONS IN SPACE. I AM CONVINCED THAT NAZI/ISRAEL AND PAPERCLIP & TALPIOT PROGRAM DID 911 WITH EMP DEW SEE DR JUDY WOODS 'WHERE DID THE TOWERS GO" I SUSPECT PINE GAP OR TESLA TECH AT HAARP CAN ALSO CAUSE VOLCANIC ERUPTIONS AND EARTHQUAKES THAT CAUSE TSUNAMI AT WILL AND THIS WAS BEHIND 1992 ACHE TSUNAMI INDONESIA TO BRING IN ISLAMIST SHARIA LAW AND CHUMBUK WHIPPING FOR CANABIS USE WHICH MUSLIMS ARE NAMED AFTER BECAUSE OF THEIR MAUSLIM HEMP/CANABIS TEXTILE CLOTHING. ITS A GIVEN THAT IN 2011 FUKUSHIMA NUCLEAR DISASTER WAS ALSO CAUSED BY SIMILAR EMP DEW CAUSED TSUNAMI OR BY AN ILLEGALLY MADE ISRAELI NUKE EMBEDED IN THE SEA FLOOR OFF JAPAN. ONE CAN SEE AT AUSTRALIAN EXMOUTH HAARP EMP DEW ARE SHAPED LIKE THE ISRAELI FLAG. THIS ISRAELI FLAG IS THE SHAPE OF THE ANTENI ARRAY TO HELP CLOUD SEEDING GEO ENGINEERING WEATHER WARFARE IN AUSTRALIA. I AM SURROGATE GRANDSON OF WW2 ANZAC ROYAL ENGINEER GENERAL SIR CLIVE STEEL I HAVE NO OFFICIAL POSSITION BUT AFTER I WAS TOLD IN 2015 BY BALI INTERPOL POLICE THAT NAZIES RUN INTERPOL I HAVE FOR NEARLY 10 YEARS BEEN SPEAKING OUT USA SENATOR CYNTHIA MCKINNEY EXPOSED THIS ISRAELI LOBBY AFFECTS ALL WESTERN SYTLE DEMOCRACY. THE CURE FOR WHAT RICHARD DAWKINS CALLED "THE GOD DELUSION" IS DARWINISM IN 1999 I WORKED FOR WW2 NAZI COLLABORATING PAPISTS AT GENERAL ELECTRIC ATM MACHINES MELBOURNE GE CAPITAL IT SERVICES AS A UNIX/ORAGLE DATABASE SYSTEMS ADMINISTRATOR. VICTORIAN LIBERAL PREMIER JEFF KENNETT USED COG , CONTINUATION OF GOVERMENT, MONEY USA PROFESSOR PETER DALE SCOTT TALKS ABOUT AS A SCAM ALSO INVOLVED IN 911 AND IN AUSTRALIA COG WAS USED AS A SLUSH FUND TO Y2K PROOF VICTORIA AUSTRALIA ESSENTIAL SERVICES AND OUTSOURCE THEIR IT DEPARTMENTS TO GE CAPITAL ATM MACHINES IT DIVISION, GE ALSO RUNS FUKUSHIMA NUCLEAR POWER PLANT SO I SUSPECT COG PROMOTES DISASTER CAPITALISM IN AUSTRALIAN AND USE OF NUCLEAR POWERED EMP DEW WEAPONS TO BE USED ON OTHER NATIONS ESSENTIAL SERVICES IS ISRAELS PLAN TO RULE EARTH. AND IN 1997 I WAS OUTSOURCED FROM STATE REVENUE OFFICE VICTORIA IT DEPARTMENT TO GENERAL ELETRIC CAPITAL IT SERVICES. AND IN 1999 I UPGRADED A FEW VICTORIAN ESSENTIAL SERVICES LIKE SRO AND POWERCOR AND GE CAPITAL ATM MACHINES ASIA PACIFIC REGIONAL SYSTEMS TO ORACLE FINANCIALS ON UNIX COMPUTERS TO Y2K BUG PROOF THEM . PRETTY SOON AFTER GE CAPITAL IT GAINED CONTROL OF WEST VICTORIAN POWER SUPPLY VIA GE CAPITAL IT SERVICES THAT ALSO DISTRIBUTES SNOWY MOUNTAINS HYDRO ELECTRIC POWER TO SOUTH AUSTRALIA , "ENRON" STYLE SOUTH AUSTRALIAN POWER OUTAGES STARTED REGULARLY OCCURING SO I SUSPECT ALL STATES ELECTRIC AND TELE COMMUNICATIONS SYSTEMS ARE BEING RACKETEERED BY ISRAELI ROTHSCHILDS ZIONIST POST WW2 NAZI WHO TYPICALLY DO ACTS OF FALSE FLAG TERRORISM AND TREASON. I AM SURROGATE GRANDSON OF WW2 ANZAC ROYAL ENGINEER GENERAL SIR CLIVE STEEL I HAVE NO OFFICIAL POSSITION BUT AFTER I WAS TOLD IN 2015 BY BALI INTERPOL POLICE THAT NAZIES RUN INTERPOL MICHEAL SHRATT TALKS ABOUT THIS IN "THIS IS THE CLASSIFIED SPACE PROGRAM" THAT NAZI ZIONIST DEEP STATE ALSO DOES UFO HOAX FALSE FLAG TERROR EVENTS SUCH AS WESTALL UFO EVENT MELBOURNE 1968 FIVE YEARS AFTER JFK ASSASINATION.. ZIONISM IS THE PROBLEM THAT LED TO AUSTRALIA CHRISTIAN ZIONIST PM SCOTT MORRISON LEASING OUT DARWIN HARBOUR TO COMMUNISTS.

what a woman Eagleton is ! promotes marxism and then complains about censorhsip. like Marx, hes all head , no heart, no humanity

Love Cole!

Summary 00:16 The Smc5/6 complex is targeted for degradation by the hepatitis B virus. 00:23 The work is a collaboration between academic groups and HPV care. 00:32 Research on HB X protein targeting Smc5/6 complex began at University of Geneva. 00:43 HB X identified as targeting Snick 5:6 complex. 00:50 Collaboration formed between Gilead Sciences and research groups to confirm findings. 01:11 Chronic hepatitis B virus infection remains a global health issue. 01:40 Antiviral therapies available for chronic hepatitis B virus infection. 01:54 No curative options currently available for chronic hepatitis B virus infection. 02:06 Complications from chronic hepatitis B virus infection include liver cirrhosis and hepatocellular carcinoma. 02:10 HPV replication cycle involves viral DNA genome deposition and transcription of viral RNAs. 03:26 X protein is essential for viral transcription from CC cDNA in vitro and in vivo. 03:49 HB x combined into a cellular ubiquitin ligase complex called the DDD1. 03:56 The substrate of this complex was not identified. 04:01 Many viruses are known to degrade the host Smc5/6 complex. 04:08 Exploiting the host ubiquitin proteasome system to degrade antiviral factors. 04:22 Viruses like HIV-2 protein VPX target antiviral factors for degradation. 04:25 Other viruses, such as papilloma viruses, promote cell growth by targeting restrictive factors. 04:38 Paramyxovirus MeV encodes a protein V to degrade immune factors. 04:43 Proteins like X and V bind to complexes to degrade intrinsic immune factors. 04:49 The target of the X protein complex was a subject of study to identify. 07:58 During infection, the Hepatitis B Virus X protein hijacks the cellular machinery to degrade the Smc5/6 complex, allowing for viral RNA transcription. 08:23 Overexpression of wild-type or mutant forms of the HBx protein in cells showed differential effects on the levels of the Smc5/6 protein, indicating the impact of HBx on the complex. 09:20 Researchers continued studying HBV infection in human hepatocytes in vitro. 10:03 Confocal microscopy was used to observe HPV infection in primary human hepatocytes. 10:50 Smith sex degradation was observed at both single-cell and population levels. 11:03 In uninfected hepatocytes, 98% of cells were positive for smick sex. 11:16 Around 12% of infected cells remained smick six positive. 11:41 A humanized mouse liver model was analyzed for HBV infection. 12:11 Humanized mice were infected with wild-type virus, showing 90% infection in pata sites. 12:32 Liver tissues were analyzed for smick 6 levels and viral markers. 12:57 In infected mice, smick 6 depletion and viral antigen presence were observed. 13:33 The study demonstrated smick 6 degradation both in vivo and in vitro. 13:43 Investigating the impact on wild-type HPV infection with depleted ubiquitin ligase machinery. 14:11 Observing the effect of depleting ligase DD b1 on viral RNA detection during infection. 14:36 Noticing robust levels of viral RNAs in Delta X-infected PHH with SI RNA control. 14:51 Highlighting the essential role of the X protein in viral transcription from CC cDNA. 14:58 Revealing the presence of the Smith v 6 complex despite DD b1 knockdown and its impact on viral transcription repression. 15:09 Demonstrating rescue of transcription from CC cDNA upon snick 6 depletion and antigen production levels. 15:59 Depletion of Smc5/6 led to increased HPV core antigen production. 16:42 Knocking down Smc5/6 complex resulted in antigen production during HPV infection. 17:24 The Smc5/6 complex may repress transcription by binding to CC DNA. 19:35 HBx protein redirects the ubiquitin ligase to degrade the Smc5/6 complex, affecting transcription. 19:57 The Smc5/6 complex associates directly with CC DNA, suggesting a mechanism of transcriptional inhibition. 20:06 Further investigation is needed to understand how the Smc5/6 complex represses transcription. 20:17 The study raises the possibility of developing therapeutic agents for chronic hepatitis B virus infection. 21:16 Discussion on the potential link between Smc5/6 degradation and hepatocellular carcinoma pathogenesis. 21:47 The Smc5/6 complex may play a role in repressing transcription from other viral DNA templates. 22:05 Ongoing studies aim to understand the differences between CCC DNA and plasmids in transcriptional regulation. 24:21 Discussion on protein degradation and complex formation 24:38 Focus on protein degradation and detection methods 24:50 Inhibitor use to preserve stability of Smc5/6 complex 25:05 Implications of degradation mechanism 25:24 Investigation on the localization of Smc5/6 complex 25:44 Detection of Smc6 in nuclear foci 25:59 Research ongoing on viral genome localization 26:12 Appreciation for the discussion

Altogether too unfortunate that a group of "Christians" with far-right ideologies are loud enough that the rest of us who value Judeo-Christian values (as mentioned in the lecture) are lumped in with them. Our faith is much more diverse than the socially confused pro-War on Drugs types would have you believe. Just a lil fyi.

Terrific series of lectures, which have contributed immeasurably to my understanding of early Chinese paintings.

The higs particle was discovered two years after this video by cern

ผมหลงใหลสิ่งที่คุณทําจริงๆ...มันทําให้ผมมองเห็นชีวิต ..come..to..thailand

when he said even Hu Jintiao and Xi Jinping lived without dignity, it was realized almost 10 years later when Hu was forced out of the meeting that re-elected Xi lol.

7:40

Thank you For this

#🇷🇺#🇷🇺#🇮🇳#🇮🇳#🇮🇳#🇮🇳🙏🙏🙏🙏🙏🙏

Did they fly the Flag at half staff at Berkeley?