18 сағат бұрын
18 сағат бұрын
18 сағат бұрын
Пікірлер
@kiranfaltankar8772 18 сағат бұрын
Very good information about how to counselling cancer patients
@Buy_YT_Views_51941 6 күн бұрын
Love your channel . It has become a part of my daily routine
@CountryStrong2309 6 күн бұрын
I knew this unfortunately
@dillydalie11 18 күн бұрын
Ok.. then maybe I have 2 years left to live, thats pretty damn good if you ask me..
@user-py1xw4iy4m 21 күн бұрын
Any updates on this?
@Noodles.FreeUkraine Ай бұрын
Still glacial improvements, but at least it's going in the right direction.
@YoungLungCancer Ай бұрын
This could be a great monitoring tool
@pattin2938 2 ай бұрын
What test did you use to detect ctDNA?
@miamiblunts 2 ай бұрын
Approved by FDA
@Shaneumerbrothers 2 ай бұрын
I lost my mom two months ago Lenvatinib is useless treatment This drug has very bad effect This medicine causes many diseases in the body Kidney failure Blisters on the body Pus in the body Constipation And there are many dangerous side effects
@Shaneumerbrothers 2 ай бұрын
This medicine kills the patient before the cancer
@user-ve1dw7nc7w 3 ай бұрын
Please make new video aoh1996 in 2024
@bretthong6137 Ай бұрын
I think in November we'll see any news
@user-ch5lw2ym6e 3 ай бұрын
So far the combination has worked for me. 8 treatments with the EV lowered from 1.7-.75 down to .50 now. At 1.7 experienced Gi toxicity and was prescribed bentyl 10mg. Definitely experiencing neuropathy in fingertips, rash, some mild depression, anxiety, fatigue, loss of appetite in the beginning along with no taste. Petscan clear tumors gone in lungs, liver, and abdomen after 8 treatments. Started as bladder cancer urothelial papillary carcinoma. Radical cystectomy was performed with neobladder. Last year 2023 October ended chemo treatments, cisplatin and genmar. Following up with a few more treatments of keytruda and padcev (EV) then Petscan in three months. 🙏
@MaverickXlive 4 ай бұрын
Thanks for the information
@BUY_YT_VIEWS_m060 4 ай бұрын
Your channel is a must-subscribe
@dicktracy762 4 ай бұрын
I would only hope that it is as effective as indicated, and that it is available like yesterday. While you might not want to hurry any drug along because of possible side effects, ineffectiveness, etc., for those who are terminal what is there to lose? I also hope that it is affordable. I think everybody should pay at least something, but put it basically into the public domain like the poliio vaccine. No big pharma gazillionaires from this breakthrough drug, thank you.
@cparora5960 4 ай бұрын
Expected period after it will be available in India
@3rdLife339 4 ай бұрын
he's my Attending Doctor One of my idol Physician❤❤❤
@josegonzalez-wi4uy 5 ай бұрын
thank you
@yusifsuleiman5502 5 ай бұрын
Please, how can I watch a prostate cancer (iCCaRe) live TV educational program. Thank you.
@gopalakrishnanmahadevan4135 5 ай бұрын
F63, Diagnosed with rectal cancer. Completed 25 days chemoradiotherapy. Post therapy MRI result shows favourable response to treatment with minimal residual disease MRTRG2. Can i opt for non surgical care?
@wilsimarteles5442 5 ай бұрын
I received an email from Cidade da Esperança informing me that phase 1 of the AOH1996 trial is suspended at this time. I understood why. The trial list is already full. They shared a link for testing, but for other medications. But from what I understand, phase 1 studies are continuing.
@wilsimarteles5442 5 ай бұрын
What is the expected date for the release of the AHO199 molecule tablet?
@bretthong6137 Ай бұрын
It's in phase 1 trail. I think in nover or so they will start phase 2 if all goes well
@amanda737h 5 ай бұрын
Will this work on Renal cell carcinoma? Aka kidney cancer.
@bretthong6137 Ай бұрын
They said on like 70cancers I'd say so
@old-n-gettinolder 6 ай бұрын
Why are so many unaware of the cost of medication and treatment research and development??? Ongoing medical research, especially for the endless types of cancer, is focused on finding safe and effective treatments, which in the U.S. cost to make it to patient care. Many never make it to human trials. Does the public expect private companies to simply absorb the loss?? That will clearly inhibit and reduce further research and development. The government allocates a limited amount of funding.
@old-n-gettinolder 6 ай бұрын
Dr. Malkas, (please fwd this comment) I am very impressed with your work, and enjoyed your visit with NGT on StarTalk. As a physician not in the field of cancer research or treatment, I applaud your transparency and candid communication related to cancer formation and treatment. May your work be productive and help many.
@Luciano-IL 6 ай бұрын
The first thing, even if the drug will be approved, only the rich people can receive this treatment. and will past another 5-7 years until will be on the market. For my very sick wife it will be too late....... 😪😮💨
@old-n-gettinolder 6 ай бұрын
There may be resources to help pay for treatments not covered by health insurance. Check with your cancer physician for options. Also the American Cancer Society. Typically no assistance will be offered unless you pursue it. Best of luck
@Luciano-IL 6 ай бұрын
@@old-n-gettinolder Thank you for your advice but we are living in Israel and the medical system did everything for her. Even if there is no hope they are still take care of her....
@RollinMyOwn 6 ай бұрын
What about it's effect on pheo/paraganglioma patients...will it work for them
@zainsheikh796 6 ай бұрын
My intro : I have metastatic breast cancer, Liver and bones, Er+, PR+ Her2-. I am a 55-year-old mother of 4 kids and post-menopause. Condition: No physical pains, Feeling normal but weak. Eating normally. I've been on a regimen of Palbociclib and Letrozole for the past 19 days, and recently, I received my CA153 test results. Last month, before starting the Palbociclib and Letrozole treatment, my CA153 level was recorded at 137. However, today, my most recent test indicates an elevation of CA153 =267. Platelets low to 159 WBC 2.9 HB 10. Before that, I had 15 weekly Taxol (paclitaxel) sessions. Until 12 sessions, CA153 decreased to 83 but again started rising to 137, so the Doctor prescribed Palbo + Letrozol. Started pacli from 142 CA 153. So can you please provide your experience? Does Palbociclib and Letrozole take longer to work? Should I give more time to see its result ?
@moradmun 7 ай бұрын
I apologise for my diminishing grasp of biochemistry, as it has been quite a while since I studied the subject at university. However, I would observe that AOH1996 looks somewhat like an aminated analog of acetic acid. For info, amination is formation of a carbon-nitrogen (C-N) bond in an organic molecule (typically achieved with ammonia, amines, or other nitrogen-containing nucleophiles to organic compounds). Perhaps other KZfaq follower with better background in biochemistry (or organic chemistry) could offer a more useful view? If my guess is correct, it should be relatively easy to synthesise this molecule by nitrating vinegar for example, assuming that the trials will continue to show promise - but not before all tests are concluded. Whatever our reservations, science is our best ally. Best wishes.
@hstrinzel 7 ай бұрын
I guess the main problem is the American Money Association (also known as AMA). IF it CURES, that's bad, no profit. IF it's not EXTREMELY expensive, there is no profit. Sad, but the AMA is probably the biggest cancer going on.
@blblawhoo4338 7 ай бұрын
i disagree, I think they sell it for a price, and cure people.
@hstrinzel 7 ай бұрын
Well, Cancer IS one of biggest profit centers in the industry. It's a bit like Co**id. Every ventilator-dead person resulted in a cost/profit of $1Million+ Multiple times as many /100000 as in Germany. There IS a $ystem going on. We had the highest hospital deads. I hope that OAH1996 can SHINE in some other countries, and it will be made known where, and then patients can flock there and get cured.
@delongbear 7 ай бұрын
What you have to understand is that the medical industrial complex will lose incalculable amounts of money. The Germans cured cancer in 1944 and the medical community has been killing us for decades.
@taluaigaluega905 7 ай бұрын
How can I get into this trial? Let me know where. I lived in Portland Oregon.
@ecancerorg 7 ай бұрын
Trial info can be found here: classic.clinicaltrials.gov/ct2/show/NCT05227326
@blblawhoo4338 7 ай бұрын
I hope you guys will give some great news for the next looks like in September in 2024 , hopefully going to phase 2 data comning out@@ecancerorg. I would think if the data is great, then phase 3 it will be mass produced
@bretthong6137 Ай бұрын
Did you get on it?
@charlottehayward5943 8 ай бұрын
If big pharma gets it it will be too expensive to help anyone.
@Enigma0071 4 ай бұрын
And they will get it. Big Pharma will either buy the patent or won't allow this drug to reach the market for years. They have FDA at their disposal.
@kisslena 8 ай бұрын
Important findings! Thank you.
@susansweetser4963 8 ай бұрын
I have a dog I need to try it on hes like my child , I want to save him , he has a large tumor way down the base of his toung they cant operate on it they said it will eventually cut off his food and water in take😭 does any know of anything I can try😭
@Schnellanie 6 ай бұрын
Look into Artemisinin and if you have a vet nearby who uses it, I've taken the liposomal form and got good results. All the best for your pooch!
@maryruiz6814 8 ай бұрын
I have couple of people that would like to join human trials in Turkey. How can we contact to join to the clinical trials?
@Schnellanie 6 ай бұрын
This is currently only offered in the US...
@VernCrisler 8 ай бұрын
I believe Dr. Malkas is deliberately playing down or lowering expectations for AOH1996 (calling it an "olive" for instance). However, if it works on humans as well as it does on animals, it's going to be a game changer just like GLP-1 and GIP agonists are for diabetes and obesity. We are living in exciting times in the field of medicine.
@73maxoneit 8 ай бұрын
If you search online, many sources say it started the human trial on the first patient in 2022. Now they say august 2023. I hope I am wrong but I do not like it.
@VernCrisler 8 ай бұрын
@@73maxoneit My understanding is that they are testing the drug for safety at this point. That usually involves testing it on healthy people. IOW, they are following the FDA's procedures for testing and approval of medications.
@73maxoneit 8 ай бұрын
@@VernCrisler cancer drugs are a class on their own
@73maxoneit 8 ай бұрын
@@VernCrisler You would think that way…but no. As cancer patient I can tell you no, the normal way in these cases, given the enormous risks of adverse events (90% of trails fail phase 1) it is given to late stage patients. But you can check online, it does not let me paste a link to one of the many official sites. One of the paradox is in fact that from time to time they discover that a last line drug would work better as first line drug.
@73maxoneit 8 ай бұрын
@@VernCrisler and from time to time, as for arx517 molecule, the results are so promising that FDA can fast track the testing process
@JamesBond-td7li 8 ай бұрын
What is PCNA ?
@wjckc79 6 ай бұрын
PCNA stands for Proliferating Cell Nuclear Antigen 1. It is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication 12. PCNA is a homotrimer and achieves its processivity by encircling the DNA, where it acts as a scaffold to recruit proteins involved in DNA replication, DNA repair, chromatin remodeling, and cell cycle regulation
@ekitt7629 8 ай бұрын
Why trials? Have a patient sign a waiver and get cured.
@dicktracy762 4 ай бұрын
Exactly. Thing is, it makes too much sense.
@vishnu11d11a0535 9 ай бұрын
My wife cured for breast cancer, now it spread to bones, how to deal with it, is it curable? Please advise
@BrandiXo 9 ай бұрын
Cancer survivorship care in us not so great
@DistractedAlly 9 ай бұрын
So how many individuals were tested total and how many had new cancer detected? I am welcome to new information though. Please present links to these followings, so I may keep up.
@DistractedAlly 9 ай бұрын
This has provided no new information.
@alpinecenter 10 ай бұрын
I can't listen to this. How many, many times have we heard exciting news about a new cancer "cure" and then never heard about it again? Something is going on here. I don't know if the drug fails clinical trials, and then is withdrawn from FDA review, or the drug actually works and for some reason is not FDA approved. There may also be big Pharma dollars or even political considerations involved in all this. Whatever the reason, the American people are deliberately kept in the dark. Why?
@73maxoneit 10 ай бұрын
first patient was given this pill in 2022 (there are various articles about this online), now you are saying that phase 1 just started and recruiting (for 8 subjects) is still ongoing....this is quite confusing...
@blblawhoo4338 9 ай бұрын
ill second this
@Schnellanie 6 ай бұрын
When you look at the current study it shows that patients are giving doses for 28 days and start the cycle again if disease doesn't progress or there isn't unacceptable toxicity. Phase 1 started in 2022 and it looks as if study ends next year.
@73maxoneit 6 ай бұрын
@@Schnellanie correct, trust me being an (ex) researcher and a cancer patient myself I know how to read studies. But this conflicts with the statement that the first patient has been dosed in August 2023 then.
@Schnellanie 6 ай бұрын
@@73maxoneit agreed. Nice to meet another patient. Also, there are too many of us...
@73maxoneit 6 ай бұрын
@@Schnellanieway too many! Hugs to you
@jimb5246 10 ай бұрын
Are the trials still open? My daughter has synovial sarcoma and this looks like a better treatment
@blblawhoo4338 9 ай бұрын
id email the city of hope cancer place, might be able to do in phase 1 or 2 but i dont know
@VernCrisler 8 ай бұрын
I think the first trial is using healthy people, so they can find the right up-dosing schedule -- toxicity, side-effects, etc. I guess it's the FDA's do-no-harm requirement.
@73maxoneit 8 ай бұрын
@@VernCrisleryou never use healthy people for such experiments but mainly people at last resort as it’s on them that such cures are going to be used.
@Enigma0071 6 ай бұрын
@@VernCrisler if FDA's has "do-no-harm requirement" then tehir wont be any Chemo drugs out there...FDA will delay this as long as possible because this can impact Chemo drugs sales
@waqarali-mi1ph 10 ай бұрын
Is there anyone who can tell me How i can get this drug from abroad as my mother is at last stage of cervical cancer
@Schnellanie 6 ай бұрын
It still is in trial phase and doesn't seem to be offered in other countries. Depending on where you're at have a look if you can get Mistletoe therapy for your mom, it helped me a lot recently and without it I wouldn't be here anymore. Wishing you all the best!
@Hhhhaaattt 10 ай бұрын
And it will cost a fortune
@evald80 10 ай бұрын
Why not making it public so other researchers can put efforts on it? Other clinical trials can be done in parallel. Most important, whoever in the pharma industry or related cannot stop it. They "buy" everything and shutup everybody. The economical impact worldwide is huge. You cannot just keep it in one hospital and research center. Make it free and spread the knowledge.
@VernCrisler 8 ай бұрын
They have to go through several trials before the FDA will approve it. They're doing the safety trial right now.
@entropy2002 8 ай бұрын
@@VernCrisler Too bad they skipped all those pesky requirements with the v @ x
@psmith7781 6 ай бұрын
@@VernCrisler My wife has grade 4 Glioblastoma. W would gladly take any risk to save her. If the FDA "expedited" any of these promising trials like they did the COVID vaccine, they could possibly save or add several years to patients around the globe that have little or no hope.
@Enigma0071 4 ай бұрын
@@VernCrisler They are just killing time. It has been known since 2022 that AOH1996 is non-toxic. They probably are cracking a deal with big pharma to either sell patent or delay the trials so that their is no impact on sales of patented drugs for next 5 years
@edwardduda4222 Ай бұрын
That’s not how science works. You test, and then publish for other people to review it. Also suspending progress on other treatments would cause more harm than good. There are hundreds of forms of cancer and this doesn’t treat all of them.
@narcisachiqui5901 10 ай бұрын
Saludos, Como acceder a este tratamiento?