The first two lectures in this series are basics and more important than the entire series, however the latter are clinically very important. I so wish Prof Rondon could develop a series on potassium and calcium.
@Mystichomey4 ай бұрын
Underarted lecture
@ahmedsalim79886 ай бұрын
The best ever lectures I have come across Many thanks
@Olelatsa6 ай бұрын
Thank you, clearly explained
@user-vh8fu8xn5x9 ай бұрын
Hi, dear Helbert! 10:31 In many textboos of physiology sodium cations are said to be more impermeable than potassium (For eaxample if we talk about non-excitable cell in terms of Holdmann equation the conductance for potssium is greater than for sodium). This explains in a manner why ECF contains more sodium than ICF and opposite true for potassium. But how can it be that in conditions of hyponatremia potassium ions leaving cell more than usual? Does it necessarily mean that conductance for that ions also changes under the influence of abnormal extracellular sodium concentration? Cells are trying to save membrane potential rather than "electroneutrality" as you said, aren't they? Thank you!
@helbertrondon46229 ай бұрын
Thanks for your comment. This does not occur in hyponatremia per se unless there is also concurrent hypokalemia.
@user-vh8fu8xn5x9 ай бұрын
@@helbertrondon4622thank you! And one more question😅 Edelman and Rose in their works suggest the term "total exchangeable sodium (potassium) concentration". What does "exchangable" stays for? English is not my native,so the probably obvious word in such context lacking explanation for me
@gilfordmutwiri2840 Жыл бұрын
Excellent talk
@myspringatgate2007 Жыл бұрын
Thank you so much for putting together such a clinically relevant (but also physiologically intuitive) approach to hyponatremia.
@nathgoody5905 Жыл бұрын
Dr Rondon... Thanks a lot🇮🇳
@nathgoody5905 Жыл бұрын
Thanks a lot for the concepts🇮🇳
@drafzal57922 жыл бұрын
One of the best lecture explaining the concepts wonderfully well. Thanks a lot
@nicolasmossof.46373 жыл бұрын
1:15 When you put Dr. Rondon and John Bonham together you know that nothing can go wrong. Muchas gracias Dr., por favor siga compartiendo!
@niakhaleenkeita3 жыл бұрын
Master class 🤩
@rrrr67643 жыл бұрын
How about normal total body water but decrease total body sodium. Can it occurs?
@helbertrondon46223 жыл бұрын
chui柏維 No
@augrajuprety8191 Жыл бұрын
@@helbertrondon4622 sir, can it occur in the correctional phase of hypovolemic hypernatremia with free water or hypervolemic hyponatremia by diuretics?
@drabhijeetchopade3 жыл бұрын
Excellent brilliant. Being a endocrinology fellow i have read this topic multiple times. But your explanation and teaching was top notch. Thank you sir. Hope to get many more video lectures from you.
@sheenasantos-alipio82673 жыл бұрын
What is the difference doctor between total body sodium, plasma sodium, exchangeable sodium?
@rboorgu13 жыл бұрын
This one is great also. Thank you for posting these.
@rboorgu13 жыл бұрын
Dr Rondon I enjoyed your lecture very much. I was wondering how you got the formula for calculating total body sodium at 0.91 g per kilogram
@helbertrondon46223 жыл бұрын
It is not a formula. It is the total body sodium measured with radioactive isotopes published in the literature. The literature says approx. 40 mmol/kg of body weight. So 40 mmol = 40 mmol x (1 mol/1000 mmol) x (22.9 g/1 mol of Na) = 0.91 g
@rboorgu13 жыл бұрын
Thank you!
@pietndala73944 жыл бұрын
Somehow if low solutes intake implies low sodium intake, that will result in hypovolumiae by definition hence it must be placed in the second group but not the first!
@helbertrondon46224 жыл бұрын
piet ndala Not really. Low Na diet does not cause hypovolemia. Yanomami Indias in the Amazon jungle ingest less than 1 mEq/day of Na their diet and have no issues. The benefit of this low Na diet for them is the prevalence of HTN is extremely low.
@pietndala73944 жыл бұрын
Helbert Rondon . Thank you Dr Rondon. Please educate us WHY fixed urinary osmolality in SIADH. Great presentation, thoroughly enjoyed,cant wait for more electrolytes
@pietndala73944 жыл бұрын
Lecture 1 from 11,52 minutes-13,13...
@Gnokhi4 жыл бұрын
Nice... One doubt... How does "Pressure Natriuresis" fit in this...?
@helbertrondon46224 жыл бұрын
Pressure natriuresis is related to BP control. It is a mechanism to maintain normal BP when changes in ECF volume and arterial BP occur.
@mikumarjha90944 жыл бұрын
Great sir..pl sir..more and more videos
@kalijasin4 жыл бұрын
Thank You Dr. Rondon
@bobufc5 жыл бұрын
This lecture is gold, Dr. Rondon! Reminded of the good old days as your resident at the renal consult service.