Excellent insights clearly explained...particularly the paradoxical aspects of calcium burden and exercise , and many other topics.

Very useful👍

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You need to listen to the people you interview!

I think it's a multi-variable calculus problem that will someday be simulated by computers when the adaptation process is better understood.

Tim Noakes would disagree about the need for carbs for exercise. He has done a 180 degree turn from his earlier view.

I remember watching a presentation by Jeff Galloway. People certainly did get injured during the 70s running boom. That’s why he came up with run walk. But it’s not like run walk was anything new because scout pace was around before that. Scout pace was almost certainly copied from somewhere else. There’s nothing new under the sun as the saying goes.

Very informative. Great guest👍🏼💪🏼😊

Are there potential signs of pre afib in otherwise healthy long distance runners? Bradycardia with escape beats? Chronic mild elevations of AST?

I really appreciate what you are doing with this channel. It is good to hear from those that actually do research.

22:03 I could relate perfectly to this point, switching to a more cushioned shoe from one with little to no cushion. Last Sunday I got a new shoe, and it happened to be my long run day, so I took it out for a spin. Completed it fine, but ended up with a nagging ache in my medial arch of the right foot (which still persists as I am typing 🤣). So, consider this lesson learned for me.

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Excellent - will listen to this again (and Episode 69 which is what led me here). 0ne big message was that hearts like vigorous exercise. Dr Levine is not only clear, thoughtful and authoritative but wise enough to caution about specific (rare) circumstances where exercise can be risky. Big thanks for valuable insights, and for letting him talk mostly uninterrupted.

RIP David. 😢😢

We need a summary. Confused the heck out of me. When Insulin is higher and longer than others people then it is diabetes. When the pancreas is not secreting Insulin for glucose presence meaning there is a deficiency of Insulin, it is diabetes. Which one is really diabetes, or is it both conditions?

I have had afib but it wasn't due endurance exercise but rather mitral valve regurgitation which changed the shape of the atria. The changed shape or remodeling is believed to have set off the afib, which was quite severe. Severe means experiencing bpm from 60 to 200 within seconds and back down again. It was way more than uncomfortable but downright hazardous in terms of stroke risk. I have always been an amateur cyclist and that gave me the reserve to survive open heart surgery to fix the mitral valve and afib.

Interesting and helpful information. My least favourite part of listening to researchers is them very casually describing animal studies that cause suffering in these unnatural imposed conditions. Hard to hear.

What is the minimum protein we need when we are not trying to gain more muscle mass? I know we can go all day with zero protein but do we have to eat twice as much to make up for deficient days? How long can we go on say 1/2 of the recommended average minimum. What would happen if I had only 60g of protein a day for 15 days and my lean body mass was around 150 lbs and/or my healthy BMI of 20 was 152 lbs

Good stuff 👏 👍

Thanks.Thanks.🇨🇦

Fascinating. Love the data based approach Dr Levine takes

Great episode with two outstanding scientists with training from the Dave Costill Human Performance Laboratory!

Interesting facts about Jim Fix’s death

I like how you bring different opinions on the podcast to give us a nuanced picture of the current science.

The questions in this podcast were poor and came from a lack of understanding about what the constrained model of energy expenditure hypothesis is actually saying.

Dan Buettner, the Blue Zones guy, has been trying a systems approach in the US.

I've just read Johan Hari's Magic Pill. My comment is the same as him in his final chapter, Japan! A wealthy democracy with far less problem with obesity than the anglophone countries.

Interesting but the one thing he doesn't marry with exercise is nutrition, which is equally important. That would be an incredible video, to see how these issues interact.

Two smart guys trying to understand the overcomplicated world of physical activities. Seems they forgot about sleeping habits, massage, stress-free life .... I enjoyed listening!

Steroids

Fantastic

I wonder if he considered the Stryd foot pod and their RSS (Running Stress Score) as a means of measuring ones load.

A bit murky and vague in parts but, overall, a useful discussion with honest, common-sense opinions and some very pertinent truths to be considered by regular, committed and too often over-enthusiastic runners. ......What the heart often wants, the body can not deliver! Cheers.

Thank you Dr Barnes. Thank you Dr McConnel. Another great discussion.

Dr McConell. Excellent discussion. I want to recommend someone on youtube I know you will like. His name is Mario Kratz. He holds a PhD and specializes in diabetes, I think. His channel is Nourished by Science. He's a carb guy. He discusses how to eat carbs and how to use and avoid using CGMs, and much more. BTW, I hope you are running now! I just saw your chat with Dr Davis. She is amazing! I wish she were my coach 15 years ago. I also have a chronically sore left calf. And a weak right hip. So many mistakes. So much I didn't know. So much I will never know. She had it right: keep young people out of the cushy high-heeled running shoes.

Dr McConnel. I swear I wrote my first entry right after your intro. Anyway. I am only now discovering you bought the Xeros. I am glad to see you have hope.

Dr Davis knows how to promote lasting behavior-pattern change.

Thanks!

Interval running.

Tulip poplar bark or cork inner soles, flat, and a decent canvas upper, thin natural rubber outer soles. My dream shoes.

Really important show. The Xero shoes are good. Midsole strike. It requires lots practice for good form for soft landings. I didn't take it seriously enough anyway: bad diet. I had spill on a kickbike a few years back and pretty sure I got a concussion, back of head. So it's walking and cycling now. Oh, and I got super pair of shoes way back around 2012 by Brooks called Green Silence. What turned me toward all of it was someone who promoted Huraches: Christopher McDougal, on NPR, website, etc, around 2009. Thanks again Dr McConell.

Training with power turned me into a much better cyclist at 42 than I was at 24. Andy's insights were instrumental in my embracing of Sweet Spot training, which is doable for someone with a full-time job.

The online interviews with Inigo San Milan explain everything! The top exercise scientist, who has spearheaded zone two.

Gregoire is very knowledgeable and passionate about the topic. You can tell he has certainly done his research and experiments.

53:07 Again this lady goes on about glycaemic impact of fruit is smaller then if you eat starchy carbs. This is false and misleading information because CGM/glucose monitors can not pick up fructose and therefore can not inform on the damage to your liver of fruit. Since the unscientific nonsense of 5 a day NAFLD has increased, 5 a day is marketing gimmick in order sell more fruit and veg not based on any science and the liver needs time away from fruit and sugar to deplete the stored fructose in the liver. Carbs had a season once and our bodies are not use to eating them all year around.

I'm type one the only way to control my blood sugars is low carb/mostly carnivore. But I cringe when people who don't know what it like to have the problems of someone who been type one for 28 years and tries to say you are depriving yourself, like the lady says 'cutting out all the foods you like'. Well I would like to correct her and re-frame that as 'all the food you are addicted to' around 44:50. For me the bottom line is you either limit your diet or limit your life by going blind or having your feet cut off. There is no way to having your cake and eating it as far as I can see, and being able to see is more rewarding then pigging out on processed crap. By our very nature eating carbs inspires gluttony, and trust me it not a good look either and can lead to mental illness especially if you avoid animal fat.

looking forward to watching this one!!

As a 52yo runner, today's technology has allowed me to run more mileage, race faster and remain injury free. The over 50 runner that can wear minimalist shoes without injury is very rare.

I just re-listened to this. It's fine, and Coggan and McConnell are real experts. And I learned things from it, no doubt. But the whole hour and half discussion doesn't have a point unless it argues with a vague, ridiculous straw man argument like "is it true that rigid adherence to zone 2 is the only way to train regardless of your goals?" For instance, listen to the section on "what is Zone 2", Andy just rambles for a while. It's good stuff but he doesn't answer the question. Then he wanders off into a discussion about performance metrics, which is very insightful and helpful, but off topic. And that continues for the entire episode. You could listen to the Ben Levine podcast where Dr. Levine recommends a two to three workouts a week in Zone 2 in his "exercise prescription for life.". His definition of the recommended effort for those workouts is the same as San Millan's definition of Zone 2.

Just finished listening. Going to listen again. I barefoot walk indoors on a wood floor, 6-8 k steps per day. It's too uncomfortable to walk outdoors in shoes, even in minimalist shoes. I don't know why. Maybe something to do with being 70, ankle issues, and shoes.