Sir aftr entering the ligand file name in the CMD, It is only showing the list of PDBQT files in the ligand.txt file. Vina is not running
@ofosuhemaajoyce94788 күн бұрын
If I may know why did you select a specific chain
@srutishreesarma487011 күн бұрын
sir, can you tell which scoring is used in this method, AutoDock 4 or Vian scoring function?
@Zhou-n6y12 күн бұрын
Hello, how does HEX do macro docking? I need your help.
@ayorindeakanbi197012 күн бұрын
Thank you Dr BB, for this video and taking time to share your expertise. You’re making a huge global impact. Best regards, Ayo (Nigeria)
@Zar.noushzadeh13 күн бұрын
Thanks for your precious information 🙏🏻♥️
@dharshudharbar23 күн бұрын
finally i got my output with your tutorial, thank you sir... but i haven't get any rmd table in dlg file and i have get no more hydrogen bonds are created in analyzing conformations, may i know the reason sir and please tell me how to rectify it
@zainabqureshi917823 күн бұрын
beautifully done
@avantikaachari474729 күн бұрын
Sir one request : plz suggest some list of good laptops for doing molecular docking project!!!🙏🏻🙏🏻🙏🏻
@prakashj7199Ай бұрын
If you are a long time Linux/*nix user, you may backport latest gromacs from Debian Sid repository and rebuild it from the sources.
@SURAALZUBAIDI-c5iАй бұрын
the music in the background of the video so annoying , id appracite to you is you make it without music so we can foucs on the explination well
@duafatima6283Ай бұрын
Hi, why did you predict the transmembrane region?what is it's importance?
@kshitijmohan6987Ай бұрын
If you don't have coding experience or a powerful computer, you can use QuandleLabs to use all of the above tools completely online
@purushottamnitwarangal9263Ай бұрын
Autogrid is not running and glg file is also not generated any solution. please help
@user-pw3ng2nu9u2 ай бұрын
Dear sir can you please teach me separately in Google meet for downloading the structure of protein protein interaction??
@tanveerhasan092 ай бұрын
Nice
@kelvinlu21112 ай бұрын
Excuse, i want to ask if i am not working on gene cloning; rather, I am conducting gene expression experiments. How can I avoid incomplete gene amplification when designing primers?
@sehrishkakakhel36432 ай бұрын
Can we run in Intel gpu
@Manohar.S.Naik.R-Biology.2 ай бұрын
Good morning sir, I am Manohar Naik your Junior in sku from Kadiri sir , I have a doubt how can I contact you sir I have no number sir
@wasifullahdawar69622 ай бұрын
Sir g You are the only one who not work for only to get views but to help someone
@Howling-wolf.2 ай бұрын
great sir thank you, the links in the description are more precious
@lifesciencedecoded3 ай бұрын
Sir which software is used to predict the anti-cancer compound ?
@MashiDani3 ай бұрын
3h42 and 3m0c are in complex. did you seprate them before?
@MashiDani3 ай бұрын
why did you use hex when it was non validated
@rosmintreesamathew38433 ай бұрын
Sir , what if the ligand is not inserted to the protein
@70pradeepyadav53 ай бұрын
After this step, how to get 2D interactions?
@Mahimaamrate20003 ай бұрын
I'm getting an error during running autogrid4, it's not running.
@Mahimaamrate20003 ай бұрын
From where autogrid4 comes, I'm confused
@karimbarakat36813 ай бұрын
Great video, Thanks alot and this the best lecture in docking that i have ever seen. but my question: What is the purpose of the step taken @9:10, changing the histidine hydrogens? why not +1? and why you didnt apply force field for the compounds?
@phdstudentsviews36673 ай бұрын
Can you please tell me how to run gromacs in could Google colab platform
@souvikmitra43573 ай бұрын
The best video on KZfaq... thank you very much sir
@user-fh4bw7kr8z3 ай бұрын
Please share videos on network pharmacology, QASR and DFT for drug discovery
@cristianpalacio80753 ай бұрын
Fucking hindu your video and social media is a bullshit, and your teaching is boring and deficint
@DanielLopez-uf7dw3 ай бұрын
You just saved my undergraduate thesis research. Thank you so much!!
@rohitchel56793 ай бұрын
Im performing docking on a known active site so i limited the gridbox around the active site only. Some of the conformations i got after docking were outside the grid box. Is that normal?
@camilla5324 ай бұрын
Thank you so much for this helpful tutorial! I am having an issue if I can ask. When I run the command, the cmd says that access is denied.
@manojsah65094 ай бұрын
Hi, sir , this video is very helpful to understand molecular docking with binding active site. My question is "How to know active binding site of any other protein for good result of molecular docking?????"
@labonihalder10034 ай бұрын
Thanks
@biomedicalscientistmuhammad4 ай бұрын
Exellent ❤
@nasirofficials4 ай бұрын
Thank you professor, I want linearized vector it has 7000 basepair. I tried restrictions enzyme, but I can't find valid enzyme.so I want to make primer. Please guide me. I also tried to make primers but I can't fullfil the condition of tm, gc and no of basepair. How can I do.
@marwanbahaj49744 ай бұрын
sir when i want to save the GPF then i get error and shows that you must select macromolecule before writing gpf
@MARIALUIZAPEREIRABALTAZAR4 ай бұрын
This was SO MUCH helpful!! Thank you for the amazing explanation!
@uselessminority60714 ай бұрын
this video is a waste of time, dont even bother with it. theres thousands of better options out there
@Manohar.S.Naik.R-Biology.4 ай бұрын
Sir Good evening sir I'm Manohar Naik from Kadiri ,your junior in SKU I have a doubt sir
@nguyenthaihoa32975 ай бұрын
When I read a paper about andrographolide as a potential inhibitor of SARS-CoV-2 main protease: an in silico approach. The andrographolide compound has a free energy of -3.09 Kcal/mol, but it shows great binding when compared to other compounds having more negative free energy values. I think about pressure, temperature, and pH in the body affecting the inhibitory process
@iJoseph9034 ай бұрын
Indeed, this variable influences the inhibitory process; it is advisable to do molecular dynamics calculations to complete the molecular docking calculations.
@sibtulhassanshah29905 ай бұрын
Make a clear cut video of cuda installation with gromacs why you skip that portion?
@SEEMAUNNIKRISHNAN-mw9rt5 ай бұрын
if its 430000 subcultures are there how to download it in sdf.
@saurabhmishra65815 ай бұрын
please tell me
@saurabhmishra65815 ай бұрын
hlo for link it showing does not exist where i get it
@chaserheinlander3565 ай бұрын
Why is my ligand so far away from the protein??? I know the active site of the protein
@iJoseph9034 ай бұрын
When docking, the ligand will automatically be located in the center of the box.