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2. Vascular events of Acute Inflammation ( Animation )
During acute inflammation, several vascular events occur to facilitate the immune response and tissue healing. These events include vasodilation, increased vascular permeability, and leukocyte recruitment. Vasodilation occurs due to the release of inflammatory mediators like histamine and bradykinin, leading to the widening of blood vessels and increased blood flow to the affected area. Increased vascular permeability allows plasma proteins and immune cells to exit the bloodstream and enter the tissue spaces, aiding in the defense against pathogens. This process is mediated by the contraction of endothelial cells and the formation of gaps between them. Leukocyte recruitment involves the adhesion and migration of white blood cells, particularly neutrophils, to the site of inflammation. This is facilitated by the expression of adhesion molecules on endothelial cells and chemotactic signals released by damaged tissues. Overall, these vascular events play a crucial role in initiating and orchestrating the acute inflammatory response. #AcuteInflammation #VascularEvents #Vasodilation #VascularPermeability #LeukocyteRecruitment #ImmuneResponse
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