Captopril Stimulation Test (ACE inhibitor stimulation test) is a laboratory test used to tell that the patient's high blood pressure (hypertension) is caused by renal artery stenosis (RAS) and not by any other cause.How do we know that the renal artery stenosis is the cause of hypertension in this specific patient?
Captopril is an angiotensin-converting enzyme (ACE) inhibitor. ACE enzyme converts angiotensin I to angiotensin II. Angiotensin II can raise blood pressure by 2 methods: vasoconstriction, and increased aldosterone release from the zona glomerulosa of the cortex of the adrenal (suprarenal) gland.
There are two types of hyperaldosteronism (excessive aldosterone secretion by the): Primary hyperaldosteronism (Conn syndrome) vs Secondary hyperaldosteronism.
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