Action Potential in the Neuron

Рет қаралды 2,554,297

6 жыл бұрын

This animation demonstrates the behavior of a typical neuron at its resting membrane potential, and when it reaches an action potential and fires, transmitting an electrochemical signal along the axon. It shows how the various components work in concert: Dendrites, cell body, axon, sodium and potassium ions, voltage-gated ion channels, the sodium-potassium pump, and myelin sheaths. It also shows the stages of an action potential: Polarization, depolarization, and hyperpolarization.
The animation was co-developed by Harvard Extension School's Office of Digital Teaching and Learning, and instructors for the courses in neurobiology and human anatomy.
Learn more about Harvard Extension School: www.extension.harvard.edu/?ut...

Пікірлер: 780

@bluehourcore 3 жыл бұрын

you literally just explained what takes up more than 10 pages of my textbook in a video that's shorter than 15 minutes. tysm!

@niahda8687 3 жыл бұрын

Bnerbatt 😭

@rodney9886 3 жыл бұрын

facts!!!

@HarryPotter-rl9np 2 жыл бұрын

Yaa it's too short,but it is good for revision

@elperro746 2 жыл бұрын

This is one paragraph on my text book and she made It look like 10 pages. Shitty explanation

@yourfavouritescepticx8969 2 жыл бұрын

That’s what I’m saying. These textbooks just confuse ppl 😂. I always come to KZfaq with these textbook topics

@GGG965 4 жыл бұрын

Every sentence is literally a ¨punchline¨. I wish schools around the world had the ability to convey the material that way, instead of confusing their students. well done harvard.

@naglaakhaled5259 3 жыл бұрын

Honestly yes school books just throw in a bunch of unorganized data and they only give half of the information so they can confuse you even more

@tinyr101 2 жыл бұрын

@@naglaakhaled5259 I’m currently in grad school and I feel that this statement is 100% correct. During courses, the professor/ textbook throws a bunch of information at you but you really only need the main points to succeed on tests/work outside of the classroom. Universities just need an excuse to keep students in the classroom longer and make them feel as if they ‘need’ all this information and need to pay for ridiculous tuition in order to be successful…

@Addison0526 2 жыл бұрын

@@tinyr101 yet we’re learning the same stuff, arguably in a better format, on KZfaq for free 🥴

@tinyr101 2 жыл бұрын

@@Addison0526 YEP, and I still have to waste my time in a lecture room where I wont benefit from what the prof says 🐔

@Lydianon 8 ай бұрын

@@tinyr101 It would be wonderful if they turned that around - learned the main points- the bare bones first and THEN fill in all the details. It not only could save time but lets you organize information in a more logical manner. You'd retain alot more. Because throwing it all at you at once... It defeats the whole purpose. Memorizing words and phrases without understanding them is why kids forget half the stuff they needed just to pass a test.

@travisk5589 4 жыл бұрын

Can I say that I went to Harvard after watching this video

@sanabatol204 3 жыл бұрын

Travis k yes! 👏 Be proud of yourself but remain humble - UofH Student :)

@krrishkai 3 жыл бұрын

I think you should be allowed to

@uzi6839 3 жыл бұрын

@Albert Darian you bitch stfu

@uzi6839 3 жыл бұрын

@Howard Bishop it’s a scam m8 they steal all your information

@angelusvastator1297 2 жыл бұрын

Lmaoo

@rachelthellammaa3923 5 жыл бұрын

I wish everyone well for the upcoming test! You got this! *Update: I'm now in college and I found myself coming back to this video since I have an exam tomorrow. Still extremely helpful!

@periwinkle1812 3 жыл бұрын

Thank you very much🐼🐼 🌺🌺

@denissemedina4619 3 жыл бұрын

Thank you! 🥺🙏🏻

@lauragarcia6959 3 жыл бұрын

Did you pass? :/

@ogechiobinka2031 3 жыл бұрын

Thank you.

@NathanHarrison7 2 жыл бұрын

KZfaq University!

@_Understand_it Жыл бұрын

This is by far the best explanation of action potentials I've ever come across. Thanks!

@user-nn4qw6ix4b Жыл бұрын

this 14 minute video should have been maybe 3 minutes. much better vids out there

@simranc7690 5 жыл бұрын

It took me an hour to get through the whole video because I kept pausing it to get almost two pages of notes out of it. Thank you so much!

@mbalensiefer 4 жыл бұрын

Do "Open Transcript" next time, and copy->Paste. :))

@elamathielam9084 4 жыл бұрын

@@mbalensiefer wre s the transcript?

@prerna3058 4 жыл бұрын

Me too

@Noor-mu1bl 4 жыл бұрын

Lol I thought it was just me!

@dannichols6261 3 жыл бұрын

@@mbalensiefer "open transcript" is good, but it is sometimes *better* to write your own notes from what you're hearing, as doing so likely 'sets' the info into your brain better, I think.

@maheen97 3 жыл бұрын

this 13 min video covered this content way better than my professor's 40 minute video

@davidthomaschwclmt5925 2 ай бұрын

I wish my A and P teacher would just show this video. its so helpful

@mikeish6640 Жыл бұрын

If anyone is wondering, there are things called leaky K+ gates that always allow a little bit of K+ ion movement across the membrane. This is how the resting potential is restored after hyperpolarisation (when it goes to negative). Because it's so negative inside the cell (below the resting potential of -70mV) K+ ions will move into the cell because of the electrical gradient, sodium ions can't their gates are shut. This movement of K+ ions into the cell makes it more positive and restores the resting potential. The sodium potassium ion pumps do help a little to maintain the electrical gradient, but mostly they keep the chemical gradient (Na+ in high concentration outside, K+ high conc. inside) with the leaky K+ (how many / how leaky they are) determining the electrical gradient and therefore the resting potential.

@booyah9402 9 ай бұрын

Sorry, can you explain this better? I am not understanding how the potential is restored again after hyperpolarization. If 3 sodiums and 2 potassiums pass through, wouldn't the cell be losing 1 negative ion all the time, making it even more negative?

@mikeish6640 9 ай бұрын

@@booyah9402 losing a net of one positive ion and making it more negative yes. The K+ gates "leak" a little bit. These gates are not the ion channels pumping the 3Na+ / 2K+, they are gates not channels. They stop most the K+ ions moving when shut, but a few still get past even when shut. When the cell becomes very negative on the inside the electrical difference (the potential difference across the cell membrane) is large enough so K+ ions are forced back into the cell through the K+ ion channels. This is moving from low conc. of K+ ions on the outside to high on the inside, so is moving against the concentration gradient and how diffusion would work, but the electrical difference is so big it pushes positive K+ ions into the cell to restore the electrical gradient. NA+ ions can not be pushed into the cell as their gates do not "leak". Did that help?

@Kak570 7 ай бұрын

@@booyah9402actually 3 factors contribute to RMP: 1.Na+/k+ pumps. 2.leaky k+ channels 3.leaky Na+ channels U must know permeability of k+ is much more than Na+ because of the presence of large amount of k+ channels than Na+ channels on membrane (approx. In the ratio of 100:1) As a result the cell membranes is significantly more permeable to k+ than to Na+.

@pratyaydatta4678 7 ай бұрын

In that case you can consider, more sodium ion enter the cell during depolarization than potassium ions that goes out during repolarization. @@booyah9402

@sahandsabahi4991 6 ай бұрын

Thank you. I was confused by the last part of the video where it says pumping 3 sodium out and 2 potassium in restores the cell from hyperpolarized state to resting potential. I think that last part is a bit misleading since the pump always makes the cell more negative.

@Alex-dp1bk 2 жыл бұрын

My professor couldn't make this make sense for the entire two semesters I had him. This one video explained it all to me in just 13:11. Thank you.

@aishasingh8433 3 жыл бұрын

Literally my teacher explained this concept in the worst way possible 😐 thanks to this video

@chrism5213 5 жыл бұрын

Thank you so much! This video is just what I need, it’s clear and to the point.

@teresagaines5087 3 жыл бұрын

I’m on page 4 of notes! I can’t believe how much this video is helping me understand what I believe is going to be a large topic on my midterm for an SFSU psychology course titled “Perception.” I’ve been struggling to conceptualize brain structures and brain activity that is now included in my courses. I’ve never seen any of it before and have had to slowly teach myself through videos like this when, even after re-reading the dense textbook, I still struggle to keep it all clear. As a very passionate psych undergrad who has never had to take chemistry or any class past intermediate biology, this video made me feel like I really missed out on appreciating science classes more because now that it was explained in a way I can understand, it blew my freakin mind. God I love learning.

@katjorbar 3 жыл бұрын

It all finally makes sense! This video is brilliant in its simplicity and cuts out all the fluff that made it complicated!

@melissahumphrey4331 5 жыл бұрын

Excellent Video! Thank you for speaking slowly and clearly. Very helpful!

@kristinafernando1072 Жыл бұрын

this is THE BEST action potential video out there!!! I've been struggling for ages and this video coverseverything in such a comprehensive and easy to understand manner. THANK YOU!

@nicholasbeck1558 2 жыл бұрын

Thank you for making your work available to all. I really enjoy your excellent presentations.

@DantheSWAMPY 2 жыл бұрын

As a first year neuroscience student, my lectures on the introduction to this topic was covered over 3 hours and was very confusing to understand. This managed to keep the level of detail needed whilst keeping it simple and also under 15 mins... Thank you so much, this really helped.

@nrubab8222 2 жыл бұрын

Are you an undergrad student?

@DantheSWAMPY 2 жыл бұрын

@@nrubab8222 yes

@leilacx1088 4 жыл бұрын

great video, i understand why Harvard students are so smart, if your explanations are this good online, I cannot imagine how great the lecture are in person.

@sarahdadswell3817 2 жыл бұрын

Such a brilliant, clear explanation with great animation. Huge help. Thank you

@aakashsaha8400 5 жыл бұрын

I was so baffled by the Neuroscience introductory class. This video made me understand the process so easily. More videos on topics like this are appreciated. Thank you...

@michelleplanton1873 2 жыл бұрын

Thank you! I have been reading all my material supplied and my textbooks but have been struggling to get my head around this. Now I get it! Such a brilliant and clear video.

@tenzinwangmu1757 4 жыл бұрын

So helpful ,this is my second time watching and revising AP

@julicookful 2 жыл бұрын

Ridiculously clear and helpful! I'm using it to develop content for "neurobiology and addiction" presentations. Thank you!!

@veroniquelevesque3998 2 жыл бұрын

I can't thank you enough for this video. I am a big visual learner and this should be presented in all physiology classes. Wow!

@theorionnebula9746 2 жыл бұрын

as a homeschooled kid making my own cutriculum, thank you for this resource. i learned about ion channels the other day and was like “wtf those things do” then was looking into the specific cell functions of neurons and thwy came up bigtime. everything is connected

@Rockerfeller26 Жыл бұрын

Okay...this was just about the best narration I needed to understand the concept. Just on point.

@marisolceja Жыл бұрын

This explanation with the graphics is super good. It definitely helped me learned my class material better. Thank you Harvard.

@davivvd1994980 4 жыл бұрын

this 13 min video covers four of my lectures...

@yunkegu8460 4 жыл бұрын

lmao

@mrkrieg1963 4 жыл бұрын

It covers 2 minutes of mine! That’s why I needed this

@jaffaesque 3 жыл бұрын

It's about 1/4 of my first lecture for the course...

@travisk5589 3 жыл бұрын

Sam, check out the crash course video. Each sentence is packed with info

@rawanghanem1607 3 жыл бұрын

same

@rubybhatia618 4 жыл бұрын

This is simplest vedio on Action potential....very helpful in clearing my physiology exam

@leonardocardoso1627 3 ай бұрын

This is by far the best explanation on KZfaq for the Hodkin-Huxley model. After watching it one, I understand everything about it. Amazing work, whoever made this. I'm sending you a virtual hug of appreciation ahaha

@hypnosisbyalex9459 4 жыл бұрын

omg this is the best easiest way to understand this process, I got so much confused from the book and from my teacher!!! but here you are explaining so simple !!!! thank you so much, I finally got it on time for my exams, are in 2 days!! THANK YOU

@alirazamughal9606 5 жыл бұрын

Best video. That Video helped me to understand the process much easily

@tane1038 2 жыл бұрын

This is a fantasic video. Very thorough, so well explained!

@geoffreychawesimfukwe8486 3 жыл бұрын

Well explained in a simplicitic way, best video so far covering the very topic, Thanks.

@ulu_al_albab 2 жыл бұрын

thanks so much. I think Harvard is the best channel that can explained resting membrane potential process clearly with good animation. I have been searching video like this since yesterday. I get the AHA moment!

@amsa2462 2 жыл бұрын

Such a well explained video! Thank you so much for uploading this!

@alessandromattoli298 4 ай бұрын

Absolutely clear, each sentence is an important aspect, amazing job harvard

@jagannatha.hirave6601 4 ай бұрын

Magnificent, it can't get better than this. Thank you Harvard.

@monaoconnell5650 Жыл бұрын

Excellent! I have the idea but will have to listen several more times. Thank you so much.

@vitoria96634 Жыл бұрын

Simple video! Perfect for you to have an idea about the subject before diving into it! Thank you!

@expectopatronum5038 3 жыл бұрын

this literally covered the whole unit . tysm!!

@ailajiezelperez9454 3 жыл бұрын

Love the video, totally understandable in such a short time. ❤️

@emmakaleck34 5 жыл бұрын

thank you so much. my teacher doesn't tell me shit and i was lost...then I found this video and all of my hope was restored. I love you even though i really hate action potential ur awesome of this i could cry I'm so happy. and I'm not even exaggerating

@NikkiJohnsonFreeThinker 3 жыл бұрын

This is a FANTASTIC EXPLANATION! It includes so many helpful details that are simply not covered in other videos about this subject. Thank you so much!

@ahmedelfaki2526 2 жыл бұрын

Can I conmect with you plazzz

@channelofbd5404 4 жыл бұрын

This video removed my complexities simply. Loved the way it made me understand the whole fact.

@F8LDragon2 2 жыл бұрын

Still amazes me that this universe developed such a complex organization of matter

@user-ll4gv5sg9u 2 жыл бұрын

Universe > super power > creator >✨ God ✨ 🥰 That's the one and only Truth to explain these amazing super complex operations .

@F8LDragon2 2 жыл бұрын

@@user-ll4gv5sg9u why does the universe have to be created? If it was created what created the creator? If the creator could be deemed eternal, why couldn’t this universe simply be eternal?

@Geminish15 2 ай бұрын

Alien overlords 👽👑

@F8LDragon2 2 ай бұрын

@@Geminish15 if that’s so, how did they develop? Must be just as fascinating

@britanieblackhurst9093 4 жыл бұрын

This video is amazing! It finally makes sense!

@razaaan4299 3 жыл бұрын

Thank you so much ! I've been struggling with this for a whole month and I finally got it. Thanks again.

@angelapritchard7737 4 жыл бұрын

Easy to follow explanation. Thanks so much!!!

@midlifekris6517 3 жыл бұрын

Wonderful video! Thank you for helping me to better understand Action Potential in the Neuron.

@arghyadas2836 Ай бұрын

I always come to this video whenever I need to revise my concepts. This video is packed with valuable information!

@user-eb4hc4gx5y 3 жыл бұрын

This video is just BRILLIANT. Thank you SO much!!

@veronicanoordzee6440 5 жыл бұрын

Finally a video with some content! Extension School? For an extended career? Of for extended knowledge? Watch the playlists and you know.

@mercychepi 3 жыл бұрын

My professor confused the heck out of me. This video was very easy to understand and grasp. I never thought I would say this, but Harvard is saving my grade

@sharonedigitale 2 жыл бұрын

This was a pleasure to watch. I’m not in school, just here for curiosity and I thoroughly enjoyed learning it because it was slow, simply explained, and illustrated so well. Thank you.

@Lydianon 8 ай бұрын

I'm not in school now either. Interesting how much more i enjoy learning when i do it just for fun.

@fitnesswithmaria3701 Ай бұрын

Excellent explanation which included plenty of detail. Thank you.

@miriammuller40 4 жыл бұрын

This video was a life-saver. Thank u.

@sheetalmahajan4150 3 жыл бұрын

It was the best explanation I could ever find. Thank you

@MukeshKumar-xl8tp 3 жыл бұрын

i was astonished by the way they presented this video.Hats off!!!!!!!

@KitambaraMakwani 13 күн бұрын

Your briefly explanation have cleared my mind satisfactorily

@lauramanyeruke 5 жыл бұрын

This video was very helpful. Thank you!

@sunrose6372 2 жыл бұрын

Thank you! This helped me understand action potentials a lot better.

@reyesgarcia1856 3 жыл бұрын

The best video of this theme. Thanks for saving my life

@sibusisomathibela1451 11 ай бұрын

mind blown i've been struggling with this concept all semester and it was explained in less than 15 minutes

@spacemaster8831 2 жыл бұрын

I am 14 and obsessed with a level psychology: This video was very useful, particularly for clarification and being clear and concise! For anybody confused: Basically the dendrites are decorated with synapses, which don't quite touch the next axel, but have literally less than 1 millionth of an inch between them. The dendrites decide whether to pass the stimulation on, and if yes, then the process begins. The stimulation is passed through the cell membrane (soma), through the axel (which is often covered in a layer of protective fat called the myelin sheath) where the action potential then reaches the axel terminal, and the action potential "jumps" across the synaptic gap and into there receptor sites (like a key fitting into a lock).

@jem3706 2 жыл бұрын

so smart for a 14 year old! keep it up!

@satoshinakamoto7253 2 жыл бұрын

@@jem3706 he reads, american teenagers don't read

@theundeadvolke9574 4 жыл бұрын

You have really made me understand what this topic entails..... Im totally speechless after listening to the video

@andreakurotova 4 жыл бұрын

I am having and exam in about 20 minutes. I was really worried, because I didn't understand the lecture but I found this video and it really helped me. English is not my first language so I was checking my notes as I was watching this and I understood everything. Great video. Thanks 😀

@user-wg3ym5pg7c 5 ай бұрын

This literally help me than those videos I have seen for action potentials and resting potential also the axon myelinated thing...... it's literally telling you all the basics which is why it's more understandable....very greatful for this video💯

@Sureshsadanandan 5 жыл бұрын

Fabulous extraordinary perfect !!!!!!! thanks a bunch 😄😄😄😄

@user-sq7il5dv6k Ай бұрын

I enjoyed that was this was explained. Straight to the actual details of what and how this happens. Great job!

@connollysoviet2359 4 жыл бұрын

Fantastic presentation. Well done. Very well done indeed.

@hazelpetrick8340 3 жыл бұрын

this vid gave me potential to do some serious note-taking action

@user-ei8et1fy8e 3 жыл бұрын

Haha

@meghabohra0111 2 ай бұрын

Thank you so much for this wonderful explanation!

@prschuster 2 жыл бұрын

Very complete and concise. Excellent graphics.

@samiesamie7619 4 жыл бұрын

Thank you so much for making such a great tutorial video

@yanitzadelgadotresord4779 5 жыл бұрын

Very helpful video, thank you!

@95Jamecia 5 жыл бұрын

YOU ARE A FANTASTIC PERSON. THANK YOU FOR THIS VIDEO!!!!!!!!!!!!!!!!!!!!!!!!!!!

@zahranakhostin9101 4 жыл бұрын

perfect . full of information.thanks

@pawankumarmaddhesiya9272 5 ай бұрын

Thank you for this animation based knowledge.

@abanoubmaged2101 2 жыл бұрын

this video well explanied everything i did study on cell biology and i wasnot sure about certain points i really wish you all best harvard

@custom_1233 2 жыл бұрын

Appreciable work please provide more such material to help us study Thanks a lot

@half-soul8393 Жыл бұрын

This was such a great explanation! Thank you!

@chitrabalakrishnan2725 2 жыл бұрын

Thank you so much!!! Wonderful clarity!

@kokusaibio4796 2 жыл бұрын

This is an excellent video. Best I have seen on this topic so far. I have sat through so many quirky, fun, mnemonic filled cartoon videos; so flashy and bright they are seizure inducing. Sometimes you need to just slow it down and tell 'em how it is. Subscribed!!!

@oykubozalioglu1465 2 жыл бұрын

The best video on this subject! Thank you

@ericpalmateer806 3 жыл бұрын

Big thank you to Ethan Contini-Field, Dr. Jennifer Carr, and Michael Davis for putting together such a wonderfully helpful video. Good job!

@Geminish15 2 ай бұрын

When did we start listing names alphabetically by FIRST NAME instead of last name? 🤨

@muthuveljothi4619 4 ай бұрын

Very well articulated. Thank you

@RajveerSingh-fx2bd 5 жыл бұрын

Love the visuals!

@kinjoya4926 Жыл бұрын

This was the most helpful video is my high school week, the details are perfectly explained and opened my eyes to how beautiful the science world is. This helped me way more than my teacher could ever. Her explanation are so low and pea brained compared to this whole of art. Thank you so much -santanPwopa

@thenightdances21 3 жыл бұрын

THIS IS THE BEST EXPLAINATION ON HERE!! even better than Khan academy if you are studying for the MCAT or classes! It covered every detail in my 2019 -2020 Kaplan MCAT books! Thank you!