Just an engineer here. I knew she had ldl pattern B in about 4 seconds looking at her standard panel. Her triglycerides were 3 times her HDL. She also is carb powered (low saturated fat). Her glucose is ok but $50 says her fasting insulin is high. None of this is genetic. Lifestyle. Lipoprotein (a) is not found in lesser blood panel. Largely genetic. Predictably statins made her insulin resistance worse. Notice her HDL decreased.

I noticed from that patient’s standard lipid panel that she has a Tg:HDL ratio of 2.9. Without doing the advanced lipid panel, wouldn’t that already predict a Pattern B of lipoproteins? Also, going back to the 1997 paper by Gaziano et al, that ratio has a much greater CVD predictive power than LDL, a fact confirmed by Da Luz (2008). Why not counsel the woman to increase her saturated fat consumption at the same time as lowering carbohydrate, an intervention that indeed improves the ratio?

Omg thank you so much for helping develop this test! Showed my doctor today

Her advanced lipid panel looks an awful lot like mine except for the Lp(a). My level is only 11. I have big problem with small lipid particles just like she does. My HDL-C is higher than hers even though I'm male. (The last test had me at 58. I removed soft drinks, fruit juice, bread, crackers, breakfast cereal and bread from my diet a long time ago. I still eat carbs, including rice, barley, wild rice, and quinoa, and a few low glycemic fruits.

I eat low carb(80grams) per day. But my small dense ldl is 49mg/dl(cut off is 21mg/dl)

I have HDL 88 trigs 36 LDL 220. High LDL particle count but all large pattern A. I don't hear this talked about a lot. High LDL, high particle count, but all large particle s. Strange?

Gonna ask my doctor about this. Thanks.

I've read somewhere that lp(a) had a benefit of reduced cancer risk and that a French group of octogenarian had a common factor of elevated lp(a). What was the survival benefit of high lp(a), I don't believe it is a bad mutation as it is too prevalent... so what are we doing wronged?

Any news on statin side effects? I tried twice and i get joint pain... although my MD says that does not make sense. Is this a rare but reported side effect?

Not once did they talk about inflammation! Unbelievable! 75% of all Heart Attacks, are low/normal cholesterol! 50%, what's called the sweet spot, between 50-70 mg/dl...

Great interviewee but bad interviewer