Study this Alteplase (tPA) NCLEX mnemonic and other mnemonics with Pixorize.
Tissue plasminogen activator, or tPA for short, is a thrombolytic or clot busting protein that is also formulated as drug names ending in “-teplase”, like alteplase. tPA works to dissolve clots, which is used to treat medical emergencies caused by clots that block blood flow, such as a heart attack, stroke, pulmonary embolism, and even deep vein thrombosis. Clinically, tPA is often given in the setting of ischemic stroke, and in this context, it is important to administer the drug within 4 and a half hours from the start of the stroke symptoms. Beyond this time point, the dangers of giving tPA outweigh the potential benefits. One dangerous side effect to note is an increased risk for bleeding.
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