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Amino Acid Stereochemistry R and S vs D and L Configuration

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Leah4sci MCAT

Leah4sci MCAT

Күн бұрын

leah4sci.com/a... presents: Amino Acid Stereochemistry finding R and S or D and L on Fischer Projections and linear molecules.
📺Watch Next: Amino Acid Stereochemistry R&S vs D&L • Amino Acid Stereochemi...
Is your MCAT just around the corner? Grab a free copy of my ebook "MCAT Exam Strategy - A 6 Week Guide To Crushing The MCAT" at leah4sci.com/M...
This is video 4 in the MCAT amino acids tutorial video series. How to determine if amino acids are R/S or D/L from linear and Fischer forms and how to quickly convert between them.
Referenced in this video:
Chirality tutorial series: leah4sci.com/c...
Catch this entire video series along with my amino acid cheat sheet, tutorials and practice quiz on my website:
leah4sci.com/a...
Looking for guidance on how to tailor your MCAT Self-Study journey to fit your unique background, experience, and personal goals without feeling alone in the process?
That’s what my new MCAT program is all about, join me here:
leah4sci.com/s...
Need more help? I offer private online MCAT tutoring. Details leah4sci.com/m...
Have questions? Leave a comment below this video or hit me up on social media:
Let’s connect:▸Instagram: / leah4sci
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Пікірлер: 375
@vivekkrishna340
@vivekkrishna340 7 жыл бұрын
This video should be obligatory viewing in any organic chemistry/biochemistry class that teaches L vs D orientation. Amazing
@Leah4sciMCAT
@Leah4sciMCAT 7 жыл бұрын
Haha glad it helped
@aref6561
@aref6561 4 жыл бұрын
Definitely the best
@MrRonidu
@MrRonidu 8 жыл бұрын
I never comment on public place but you so much worth a complement. You are an amazing teacher.
@Leah4sciMCAT
@Leah4sciMCAT 8 жыл бұрын
Thank you!
@Leah4sciMCAT
@Leah4sciMCAT 8 жыл бұрын
Thank you!
@jacquelineleiman250
@jacquelineleiman250 6 жыл бұрын
Compliment*
@josphellihsilak4588
@josphellihsilak4588 5 жыл бұрын
@@Leah4sciMCAT and you're sexy. Just saying. 👍
@adrimodas375
@adrimodas375 11 ай бұрын
Oi
@maggiephillips3579
@maggiephillips3579 4 жыл бұрын
Four years later and this video is still helping students! Thank you for helping me with Fischer projections of amino acids, something I was really struggling with!
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
You're very welcome, glad it helped!
@persistentconsistency
@persistentconsistency 4 жыл бұрын
Paused my biochem reading for lecture to learn a bit more about L & D since I never saw this in O-chem. Appreciate the thorough lesson!
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
So glad I could help!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
My prof never went into this either, glad the video helped
@AlanPhasavath
@AlanPhasavath 3 жыл бұрын
I like the detail you went into they usually don’t teach this into depth, they just scratch the surface and move on. Thanks for the vid it helps even 5 years later 👍
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
Glad it was helpful!
@ACDBunnie
@ACDBunnie 2 жыл бұрын
6:32-7:43 Literally, in less than a minute and a half you taught me such an easy way to tell apart an L and D Fischer projection. I thought it would take forever for me to learn how to tell them apart! Thanks again!
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
Oh wow! So glad I helped you understand it so quickly!
@TheCelticBomb
@TheCelticBomb 7 жыл бұрын
I love you so much. You are so unbelievably helpful. Not only do you explain things super well, and make everything really clear, but you also maintain an animated voice which makes all the difference. The inflections and "enthusiasm" in your speech (whether feigned or genuine) really helps to pay attention and pick up the information. You are a godsend.
@Leah4sciMCAT
@Leah4sciMCAT 7 жыл бұрын
Thank you very much! My goal is to always make it as fun as possible :)
@rubenmoreno7065
@rubenmoreno7065 7 жыл бұрын
Of all science teaching videos I've ever seen, you make the best. Infinite thanks to you!
@Leah4sciMCAT
@Leah4sciMCAT 8 ай бұрын
You're very welcome!
@fujoshipeanut5074
@fujoshipeanut5074 7 жыл бұрын
This is perfect, thank you! This is the only resource I've found that explains how to determine L and D
@Leah4sciMCAT
@Leah4sciMCAT 8 ай бұрын
Happy to help!
@angelaliu4837
@angelaliu4837 8 жыл бұрын
Thank you so much! I was panicking over having to learn this, but you made it really easy :)
@Leah4sciMCAT
@Leah4sciMCAT 8 ай бұрын
You're welcome, hopefully no more panicking!
@simplyyjhez
@simplyyjhez 4 жыл бұрын
good luck to all of those studying for the MCAT
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
Yes!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
💯
@serineprotease0105
@serineprotease0105 6 ай бұрын
This woman got me a 95% in organic chemistry 2 , and now she's carrying me in biochemistry
@Leah4sciMCAT
@Leah4sciMCAT 6 ай бұрын
Awesome! Glad to help!
@hesamb9135
@hesamb9135 2 жыл бұрын
Cannot even describe in words how amazing this video is. Thank you!
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
You're very welcome!
@amandasegura2483
@amandasegura2483 4 жыл бұрын
This was AMAZING!!! I finally get it! Thank you!!! I always thought this was difficult to understand but you made it SUPER simple! Thank you!
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
I'm so glad to hear that you understand!
@kyle4409
@kyle4409 Жыл бұрын
This is the greatest trick in organic chemistry THANK YOU
@Leah4sciMCAT
@Leah4sciMCAT Жыл бұрын
You're welcome! :)
@Frejarosaludwigfrost
@Frejarosaludwigfrost 7 жыл бұрын
This was so good! It really helped explaining what my professors or book could't, right before my exam. I quite enjoy the amount of examples.
@Leah4sciMCAT
@Leah4sciMCAT 7 жыл бұрын
I'm glad that it helped!
@sumitchand3447
@sumitchand3447 5 жыл бұрын
I am from india and i really loved and actually just grasped everything u said in minutes rather then spending hours with books and then the books made sense thanks ma'am it was really very helpful
@Leah4sciMCAT
@Leah4sciMCAT 5 жыл бұрын
Glad to help! :)
@aleensanskreetipalai9404
@aleensanskreetipalai9404 2 жыл бұрын
Just one watch and got the whole concept clear!!!!!!! Absolutely amaaaazzinngggg!😭✌️
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
YAY!!! So happy this helped you get a clear grasp on it!
@m.t1446
@m.t1446 5 жыл бұрын
Leah I love you 💕 got an A on my orgo 1 and B on orgo 2 with the help of your videos and advice. You should be on the top recommended for the MCAT exam study sources.
@Leah4sciMCAT
@Leah4sciMCAT 5 жыл бұрын
oh wow! good to know that! Congratulations! Thank you for the nice feedback. Always glad to help :).
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Oh wow congrats on acing orgo! Hope you aced your MCAT as well
@davidtomczak8035
@davidtomczak8035 7 жыл бұрын
This is fantastically well shown, explained, and produced. Great job.
@Leah4sciMCAT
@Leah4sciMCAT 7 жыл бұрын
Thank you very much. Glad you enjoyed it
@Micro-life
@Micro-life 4 жыл бұрын
Whenever i feel complications in understanding chemistry concept i refer MCAT. You are great ma'am❤ I love the way you crack the hardest topics in the most simplest manner💐 Kudos to you ma'am🙏
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
Aww, thanks for that! I'm glad my resources help you to understand!
@marrgarc6109
@marrgarc6109 Жыл бұрын
b go g
@gimyear
@gimyear 4 ай бұрын
Thank you for the great video. I really appreciate it. I can't guess how much effort this video put into it.
@Leah4sciMCAT
@Leah4sciMCAT 4 ай бұрын
You're very welcome and thank you for your kind words. A lot of work goes into this, but I love doing it!
@fabianorocha190
@fabianorocha190 7 жыл бұрын
Awesome! you've helped a brazilian medicine student! Thanks a lot. :)
@MrMegaOrestesNaruto
@MrMegaOrestesNaruto 6 жыл бұрын
like me.
@Leah4sciMCAT
@Leah4sciMCAT 8 ай бұрын
Awesome, so glad my resources helped you!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
So glad to help
@stellaquach9408
@stellaquach9408 4 жыл бұрын
literally never took organic chem and this video helped me understand the concept almost entirely omg i love u :((
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
Glad I could help!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
oh wow, that's amazing! so glad to help
@YamahaYEP321S
@YamahaYEP321S 5 жыл бұрын
THANK YOU SO MUCH!!! I was so lost looking absolutely everywhere and you had the easiest to understand lesson about this. I'm still a little confused but better than I was, initially when my teacher was showing it, it all flew over my head and I was so overwhelmed. Thank you!! I sent your link to my classmates as well!!
@Leah4sciMCAT
@Leah4sciMCAT 5 жыл бұрын
You are very much welcome! Glad to have helped and thanks for sharing the video :)
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome! Hope watching it a second time helped it all click
@Mati-wj5qo
@Mati-wj5qo 3 жыл бұрын
i'm from Argentina and i couldn't find this exactly explication in spanish, i'm so glad to have found your video thank you very much
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
You're very welcome!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Glad you were able to understand in english
@tori-mariepalmer7959
@tori-mariepalmer7959 11 ай бұрын
wow the configuration part! thanks for sharing! i totally get it now!
@Leah4sciMCAT
@Leah4sciMCAT 11 ай бұрын
You're welcome! So glad this helped you clear things up!
@mohandforstudying1886
@mohandforstudying1886 3 жыл бұрын
Not only great but is actually the best thank you for the explanation 🙏🙏🙏
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
You're welcome 😊
@mihacervek6958
@mihacervek6958 8 жыл бұрын
Awesome video, excellent and simple explanation, just what I needed. Thanks a lot. :)
@Leah4sciMCAT
@Leah4sciMCAT 8 жыл бұрын
You're very welcome
@gyedublay
@gyedublay 7 жыл бұрын
you are such a genius
@Leah4sciMCAT
@Leah4sciMCAT 8 ай бұрын
Thanks!
@kavyakothalanka5242
@kavyakothalanka5242 4 жыл бұрын
awesome!!!! i just lost my stress on covering this part of aminoacids. thankuuu soo muchhh!!!
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
Yay! I'm so happy to hear that, and you are very welcome!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
so glad this video helped reduce your stress
@mohitha17
@mohitha17 7 жыл бұрын
Its crystal clear... It helped me a lot to go further with this .... Thanq so much......
@Leah4sciMCAT
@Leah4sciMCAT 8 ай бұрын
You are so welcome!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome
@rohamhadidchi1196
@rohamhadidchi1196 7 ай бұрын
Simply incredible, thank you
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome
@keeyandatshipamba7080
@keeyandatshipamba7080 3 жыл бұрын
Thank you so much for making this video! You have helped me understand this topic more than 3 years of university could🥴
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
You're welcome! Glad it was helpful!:)
@taniartiste
@taniartiste Жыл бұрын
Thank you! Great explanation and in a simply way. I understood in minutes. Thank you for your work 😊
@Leah4sciMCAT
@Leah4sciMCAT Жыл бұрын
You are very welcome; so glad it was helpful!
@user-cl2rq5ck1s
@user-cl2rq5ck1s 7 ай бұрын
Your video is amazing! Thanks for everything😊
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You are so welcome!
@tranlenamphuong6192
@tranlenamphuong6192 Жыл бұрын
W content. Saved me from so much grief where had you been all my life
@Leah4sciMCAT
@Leah4sciMCAT Жыл бұрын
Always glad to help!
@cal-fitness641
@cal-fitness641 3 жыл бұрын
this video has made my day thanks to the uloader
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
You're very welcome!
@teacherm8647
@teacherm8647 7 жыл бұрын
really, excellent teacher, and u r using very good methods of explanation, thanks... 🌹
@Leah4sciMCAT
@Leah4sciMCAT 8 ай бұрын
you're very welcome!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
thank you
@petrabanjarnahor229
@petrabanjarnahor229 7 жыл бұрын
I love whoever made this channel
@Leah4sciMCAT
@Leah4sciMCAT 6 жыл бұрын
Thank you for your kind words!
@TheACLP
@TheACLP Жыл бұрын
for the S-Aspartate question at 21:15 if we used the guess and check method, even if we place the +NH3 on the right side for D configuration it would still be an S, so no matter the L or D conformation it will both be S, so how can you use this method if you're trying to compare the S configuration of the line and wedge to both the L and D conformation if both are S?
@Leah4sciMCAT
@Leah4sciMCAT Жыл бұрын
I'm confused by your question. If we swapped the NH3 group with the Hydrogen and had the NH3 on the right side of the Fischer, we would have an R configuration to the stereocenter. Making a swap like this changes the configuration of the chiral center. For help with questions like this and more, I recommend joining the MCAT Study Hall. For more details, visit join.mcatstudyhall.com/ or contact me through my website leah4sci.com/contact/
@hinaz6657
@hinaz6657 4 жыл бұрын
Good video for quick exam prep but not very much for learning chemistry tbh. The principle and logic behind this chemistry are not explained (which is not required if you just want to pass exams especially for premeds). But I appreciated the effort. Thanks.
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
You're welcome
@kanaitaasad7793
@kanaitaasad7793 4 жыл бұрын
Thanks a lot ,you explained it so clearly that I am finally going to complete my assignment , otherwise I was so worried.
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
Glad I could help!
@hookem3768
@hookem3768 Жыл бұрын
Why did you skip the two hydrogens of the CH2-SH group? Wouldn't the Carboxyl group have higher priority due to the amount of bonds to oxygen?
@Leah4sciMCAT
@Leah4sciMCAT Жыл бұрын
Both Sulfur and Oxygen are directly bonded to a carbon on the chiral center. If Sulfur outranks Oxygen with its atomic number, the number of bonds to Oxygen are irrelevant. Sulfur is the winner and would be higher priority.
@susieyu5665
@susieyu5665 4 жыл бұрын
I wish i found u years ago , thank you for this video, it really clarifies this confusing concept
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
So glad it helps!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Better late than never? glad it helped
@shallysharma6389
@shallysharma6389 3 жыл бұрын
Miss, I just love ❤️ to watch ur videos and do study from your lessons thanks for being my fav educator 😊
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
Thank you! 😃
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
awww thanks
@yatharthsingh5351
@yatharthsingh5351 Жыл бұрын
but we should draw perfect fischer by placing most oxidised carbon on top and maximum carbon vertically right ?
@Leah4sciMCAT
@Leah4sciMCAT Жыл бұрын
Yes, correct. For more detailed help on drawing Fischer projections, make sure to see my series at Leah4sci.com/Fischer
@Jedizorakmantis
@Jedizorakmantis 4 жыл бұрын
This was so helpful, thank you so much for sharing your knowledge.
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
You are so welcome!
@nicolasbaroni9053
@nicolasbaroni9053 8 жыл бұрын
Can you reiterate how exactly you know when to change the direction of our loop when connecting 1,2&3? Is It only when the hydrogen is coming out of the paper?
@Leah4sciMCAT
@Leah4sciMCAT 8 жыл бұрын
Go back to this series: leah4sci.com/chirality/
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
I cover this extensively here: leah4sci.com/chirality
@MrMegaOrestesNaruto
@MrMegaOrestesNaruto 6 жыл бұрын
best voice EVER
@Leah4sciMCAT
@Leah4sciMCAT 6 жыл бұрын
Thank you for your kind words!
@lenahalberstadt2587
@lenahalberstadt2587 2 жыл бұрын
Thank you! Finally it sunk in!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Glad it finally clicked :)
@ayleenc.205
@ayleenc.205 Жыл бұрын
Can somebody explain why she does the second swap (during 10:32) ? I know she said to "maintain the chirality," but can somebody explain that please! Thank you:)
@Leah4sciMCAT
@Leah4sciMCAT Жыл бұрын
At this point in the video, we are trying to transform the Fischer projection of R-alanine into proper form where all carbons would be along the vertical backbone of the molecule. That means we need to swap our carboxyl group to the top-most position, so that it falls along the vertical. When we make that swap, we also need to swap two other groups in order to maintain an R configuration at the chiral center. If we didn't make a second swap, we would then have the S configuration of alanine. Which is a different stereoisomer of our original molecule.
@shenchifeng
@shenchifeng Жыл бұрын
Amazing lecture!!
@Leah4sciMCAT
@Leah4sciMCAT Жыл бұрын
Thank you!
@2909ft
@2909ft 7 жыл бұрын
THANK YOU! YOU JUST SAVED ME!
@Leah4sciMCAT
@Leah4sciMCAT 8 ай бұрын
Oh wow, glad to help!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome
@andytan9917
@andytan9917 2 жыл бұрын
Very well explained! Save me so much time!
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
Glad it helped!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome!
@hitensingh6629
@hitensingh6629 3 жыл бұрын
I came looking for non coded Amino Acids. But I don’t think this is about that. But u could help me. So the line is - amino acids having D-Configuration or which aren’t alpha amino acids are Non coded. What does this D configuration mean ?
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
To be non-coded simply means that the amino acid was not coded for by the DNA sequence. It must have been synthesized by some other process, outside of the body. All of the amino acids derived from natural (human-made) proteins are of the L configuration. D-amino acids are found in nature.
@95kmusic
@95kmusic 2 ай бұрын
Why is the carbonyl and H in the wrong place at 10:30? Why are you swapping?
@Leah4sciMCAT
@Leah4sciMCAT 2 ай бұрын
Correct form for a Fischer projection is to have the main carbon chain along the vertical backbone of the structure. That means, by convention, the carbonyl carbon should be on the vertical line and not the horizontal. One swap of the carbonyl and hydrogen changes this to follow convention, but then we have to do the second swap to maintain the R configuration of alanine.
@95kmusic
@95kmusic 2 ай бұрын
@@Leah4sciMCAT thank you for taking the time to explain :)
@jessicaly152
@jessicaly152 4 жыл бұрын
saved my life. not to be dramatic but would die for u omg
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
Wow, thanks for the offer, but I'd rather you not have to do that :)
@sabrynamccrea4675
@sabrynamccrea4675 2 жыл бұрын
I'm wondering how you know if the H group is forward or not in the simple diagram rather than with the wedges and dashes?
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
I believe you're asking how to tell the configuration when presented with a Fischer projection. For more on these drawings, visit Leah4sci.com/Fischer
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Do you mean in Fischer? see Mr Organic Chemistry in this video or here: leah4sci.com/fischer
@Badri8877
@Badri8877 5 жыл бұрын
It was too easy to understand. Amazing, thank you.
@Leah4sciMCAT
@Leah4sciMCAT 5 жыл бұрын
You're welcome! Glad you got it :)
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Too easy is hopefully a good thing
@Luna-oq8cy
@Luna-oq8cy 2 жыл бұрын
But why is O 2 and N 1 . In your table the prioraty was for O so O is the highest and higher the N?
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
The reason is that the chiral carbon is not directly bonded to the oxygen atom. It is bonded to the carbon of that carboxyl group. Carbon is lower in priority (atomic ranking) than nitrogen. In summary, the -NH3 group receives a 1, the carbonyl group (being a carbon bonded to two oxygens) receives a 2, and the -CH3 group (being a carbon bonded to only hydrogens) receives a 3.
@yourfriendlyneighborhoodqu3859
@yourfriendlyneighborhoodqu3859 2 жыл бұрын
Another important thing levorotary and dextrorotary are not directly related to either of these
@Leah4sciMCAT
@Leah4sciMCAT Жыл бұрын
That's correct. :)
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
right? why do scientists make everything SO complicated?
@AbhishekPatel-xz2ck
@AbhishekPatel-xz2ck 4 жыл бұрын
This video is really amazing! And excellent explanation..
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
Glad you liked it!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Thank you
@jihane9065
@jihane9065 5 жыл бұрын
Thank you so much! you explain sooo well
@Leah4sciMCAT
@Leah4sciMCAT 5 жыл бұрын
You're welcome! Glad I could help
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome and thank you :)
@Gabi-op8lt
@Gabi-op8lt 4 жыл бұрын
I don't understand why you have to swap the atoms for Fischer projections..
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
A Fischer projection is the preferable model for drawing biological molecules, like amino acids. They also make it easier to determine the configuration at chiral centers. Is there a specific point in the video where you have a question about Fischer projections?
@ajinkyajadhav3424
@ajinkyajadhav3424 5 жыл бұрын
Maam my question is, in last ex.of aspartate you have shown that hydrogen atom in front to the observer but as the (Fisher projection formula) but a/c to Fisher projection rule it should be at left side of horizontal bond as it is back side of the plane, how it is possible
@Leah4sciMCAT
@Leah4sciMCAT 5 жыл бұрын
I'm sorry, but I don't offer tutoring through KZfaq comments. For help with this and more I recommend joining the MCAT study hall. Full details: join.mcatstudyhall.com
@mihaly1027
@mihaly1027 4 жыл бұрын
Leah4sciMCAT i wonder who would pay hundreds of dollars just for that question to be answered when they can simply go on a forum to ask for free
@benphung4315
@benphung4315 3 жыл бұрын
Love this video! I love how you encourage understanding, not just memorization. I struggled with this topic a lot but you made it understandable! Thank you!
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
You're so welcome! I'm glad it was helpful!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Thank you! and absolutely YES to understanding before you attempt to memorize. If you memorize you forget, and then what? If you understand you can reason your way through it because of what you truly GET
@zachp2120
@zachp2120 4 жыл бұрын
at 12:01 you said the H has to be on the bottom but when you look at the structure next to it is on the bottom? I'm a bit confused there.
@zachp2120
@zachp2120 4 жыл бұрын
Oh wait does it have to do with the bow tie ochem guy? I think i see what i did wrong now.
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
Glad you figured it out!
@faithomosor1744
@faithomosor1744 5 жыл бұрын
I think you meant to say that oxygen has more priority than nitrogen since we are going by atomic numbers not the other way around. So the carboxylic group will be number 1 and the ammonia will be number 2.
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
The carboxylic group has a carbon (not an oxygen) directly attached to the chiral center, and carbon is lower in priority than the nitrogen in the amine.
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Oxygen outranks Nitrogen, however in a carbonyl group it's the Carbon we're comparing to Nitrogen and so the amine outranks the carboxylic acid
@Obamnaz
@Obamnaz 2 жыл бұрын
Thanks for the video, I just don't get when R and S is reversed, like in 12:00. If the lowest ranking group (normally hydrogen) is to the right of the Fischer projection you reverse it, but if it's at the top (like at 9:50) or bottom then we don't reverse it?
@milok780
@milok780 2 жыл бұрын
Yes that’s right because the H is already in the back in contrary to when it is on the side and facing to the front. Hopefully that was helpful :)
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
Since we want the lowest ranking group to be at the back of the molecule when assigning configuration, we must reverse the designation if that hydrogen falls on the left or right of a Fischer projection. Because, by convention, the left and right groups are moving up and out of the page. If the hydrogen falls along the vertical spine of the Fischer projection, then it is already pointing behind the page, or to the back of the molecule. Therefore, no reversal of the R/S configuration must be made. To learn more, watch my Chirality and Stereochemistry series (especially the Swap method video) at Leah4sci.com/chirality
@Obamnaz
@Obamnaz 2 жыл бұрын
@@Leah4sciMCAT @Milo K thank you both !!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
I cover stereo of Fischer extensively here: leah4sci.com/fischer
@BattleHaven1185
@BattleHaven1185 4 жыл бұрын
Here I am studying for my 2nd biochem test and this is the first time I'm learning R & S aren't the same as D & L? my professor literally told us that they were - that L was R and D was S. Gotta love paying thousands of dollars to be given wrong infomation D:
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
Ouch! Sorry to hear that!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Oh wow, yeah my biochem professor also tripped up on R/S basics, we had to correct him
@eusebiu-petruristea4461
@eusebiu-petruristea4461 6 жыл бұрын
Great explanation, great explainer.
@Leah4sciMCAT
@Leah4sciMCAT 5 жыл бұрын
Thank you :)
@ahmedmusaomer2787
@ahmedmusaomer2787 2 жыл бұрын
Thank you so much for helping me with this video, ❤ 💕 💗
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
You are so welcome!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome
@garthswaney5439
@garthswaney5439 3 жыл бұрын
Well done explanation!
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
Glad it was helpful!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
thank you
@Yankee4ever2
@Yankee4ever2 Жыл бұрын
Leah4sci is bae af
@Leah4sciMCAT
@Leah4sciMCAT Жыл бұрын
Thanks! I'll take the compliment. :)
@marcoslofiego5584
@marcoslofiego5584 2 ай бұрын
A very useful video!
@Leah4sciMCAT
@Leah4sciMCAT Ай бұрын
Glad you liked it!
@1man1sam
@1man1sam 7 жыл бұрын
Thank you so so much for your insight! So helpful
@Leah4sciMCAT
@Leah4sciMCAT 7 жыл бұрын
You're very welcome!
@ahmedrshad7205
@ahmedrshad7205 7 жыл бұрын
thank you very much, you are really talented
@Leah4sciMCAT
@Leah4sciMCAT 8 ай бұрын
Aww thanks so much!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Thank you :)
@rajithadhanu4181
@rajithadhanu4181 7 жыл бұрын
Thank you for your videos. You are a best teacher ever.I have followed your materials to improve my knowledge. I have a question in Stereochemistry. There are some few videos in youtube that they mention III ry amine have a chiral center. There is a problem because when I do the ACS questions they not accepting it as a correct answer. please give me an answer If you have a free time to attend with this matter. Thank you
@Leah4sciMCAT
@Leah4sciMCAT 7 жыл бұрын
I'm sorry, but I don't offer tutoring through KZfaq comments. For help with questions like this and more, I recommend joining the MCAT Study Hall. For more details visit join.mcatstudyhall.com/ or contact me through my website leah4sci.com/contact/
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
This is a tricky question, Tertiary amines are technically chiral due to their shape, but the 4th group is a lone pair which is constantly inverting and so you won't ever have just R or S. Quaternary amines on the other hand can have 4 unique subs for a proper chiral center
@sayanidas170
@sayanidas170 4 жыл бұрын
Very clear explanation..thank you!
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
You are welcome!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome
@zahralahjouji5808
@zahralahjouji5808 4 жыл бұрын
you're an amazing teacher!!!
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
Thank you! 😃
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Thank you
@aref6561
@aref6561 4 жыл бұрын
Thank you so much this was great Leah
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
yvw
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome
@faithomosor1744
@faithomosor1744 5 жыл бұрын
nevermind I understand. Nitrogen is greater than carbon so the ammonia will be number one and the carboxylate will be number two
@Leah4sciMCAT
@Leah4sciMCAT 5 жыл бұрын
Glad you figured it out! Let me know if you have other questions :)
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
EXACTLY!! you got this :)
@ka6091
@ka6091 4 жыл бұрын
this is so helpful, wish I had found the video earlier
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
Glad it was helpful!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome! Better late than never, right?
@matthewmcdaniel1160
@matthewmcdaniel1160 Жыл бұрын
Does this also mean that all D amino acids are R except cysteine?
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
exactly, yes
@xxuexx
@xxuexx 8 жыл бұрын
you are very talented! great job. subscribed.
@Leah4sciMCAT
@Leah4sciMCAT 8 жыл бұрын
Thank you
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Thank you for the kind words and for subscribing
@Hyumifu
@Hyumifu 3 жыл бұрын
Thank you SO much!
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
You're very welcome!
@Hyumifu
@Hyumifu 3 жыл бұрын
@@Leah4sciMCAT ❤️❤️❤️ This has been the most helpful I can't even stress that enough 😭
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome
@riyapopat9934
@riyapopat9934 3 жыл бұрын
Thank you for your help
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
You're welcome!
@carlosekram9961
@carlosekram9961 2 жыл бұрын
That was just WOW
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
Thanks!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
Thank you :)
@soumyodeepbhattacharya6095
@soumyodeepbhattacharya6095 3 жыл бұрын
I am stunned
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
Thanks!
@Monica-qd4co
@Monica-qd4co 4 жыл бұрын
This was an amazing video! Thank you so much!!
@Leah4sciMCAT
@Leah4sciMCAT 4 жыл бұрын
You're so welcome!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome
@tu2026
@tu2026 6 жыл бұрын
Ur videos are amazing.. really its helps me a lott👍
@Leah4sciMCAT
@Leah4sciMCAT 6 жыл бұрын
Thank you for your kind words!
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome
@winsenken
@winsenken 6 жыл бұрын
So if I change the stereochemistry of specific amino acid from R to S or S to R, the the L and D configuration will also swap automatically right??
@Leah4sciMCAT
@Leah4sciMCAT 6 жыл бұрын
I'm sorry, but I don't offer tutoring through KZfaq comments. For help with this and more, I recommend joining the MCAT study hall. Full details: join.mcatstudyhall.com/
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
exactly, yes
@user-xv6us3bm5e
@user-xv6us3bm5e 3 жыл бұрын
Thanks
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
You're welcome!
@samuel-iq1sh
@samuel-iq1sh Жыл бұрын
Are D and R amino acids the same ??
@Leah4sciMCAT
@Leah4sciMCAT Жыл бұрын
L/D and S/R are two different systems for identifying stereocenters. The first gives us relative configuration, while the second is absolute configuration. It's tricky to begin to relate these two systems to each other. Rather, we treat them separately.
@sanderheyndrickx
@sanderheyndrickx 2 жыл бұрын
Thank you So much!
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
You're welcome!
@GreenOnionBrother
@GreenOnionBrother 7 жыл бұрын
Thanks, you are a life saver! Now I have to move on and deal with E/Z, though. -.-
@Leah4sciMCAT
@Leah4sciMCAT 7 жыл бұрын
Glad I could help! Is this what you are referring to? leah4sci.com/cis-trans-and-e-z-geometric-isomers/
@GreenOnionBrother
@GreenOnionBrother 7 жыл бұрын
Ah, yeah, exactly! Thank you :D
@Leah4sciMCAT
@Leah4sciMCAT 7 ай бұрын
You're very welcome! I cover that in detail as well
@Bohnr
@Bohnr 2 жыл бұрын
a little redundant... but I actually get it now. thx
@Leah4sciMCAT
@Leah4sciMCAT 2 жыл бұрын
you're welcome
@jacquelineleiman250
@jacquelineleiman250 6 жыл бұрын
Splendid video!
@Leah4sciMCAT
@Leah4sciMCAT 5 жыл бұрын
Glad you enjoyed it!
@Farhan-co9he
@Farhan-co9he 3 жыл бұрын
you are great..thanks
@Leah4sciMCAT
@Leah4sciMCAT 3 жыл бұрын
Thanks, and you're welcome!
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