oh my god, I couldn't understand this for weeks,I couldn't find any good explanatory videos and you just answered all my questions. I have my biochemistry exam on Monday. thank you

You are truly gifted when it comes to explaining MCAT content. Thank you!

Thank you so much Lea! I was struggling with this and got a 503 MCAT, now I ended up getting at 517 and will make a video about how I did it! Thank you so much!

I can't express how greatfull I am. I've been trying to understand those concepts for weeks with my regular teacher and failed miserably. This explanation was so clear, i finally understood!! Thank you so much!!

Just brilliant. Will be sharing with my past BioChem professor (she loves solid educational videos - knows students all have different learning styles) along with my Pre-Med base. Regret not thoroughly watching through these years ago.

This concept help me to crack jee advanced 2020 question in seconds ❤❤ 👍 thanks 😊

You are just so amazing Leah! You have assisted with turning the cogs in my brains just that little bit more every time!

I'm Really thankful to u for making this tutorial.. finally understood the concept 👍

Excellent job! I totally understand it now. Thank you so much.

Your voice is like ASMR, It's relaxing and soothing. I like it a lot, ever think about doing deep sleep mix tapes? 🌝

I think you may have just saved me from a meltdown. Thanks ;)

You explain everything thoroughly! Very good videos. I've recommended this to other students

Thanks a ton, this concept was troubling me from past 2 days 😇😇😇😇thank you thank you thank you for making it crystal clear.

Don't understand everything yet but very clear explanation and presentation. Thank You.

Just found this channel of yours right now! Keep up the good work Leah!!

OMG THIS IS AWSOME , I was so confused, you broke it down so so so well!!!!

THANK YOU OMG THANK YOU!!! YOU SAVED ME! IM SO GRATEFUL FOR THIS CHANNEL!!!!

It finally made sense to me while looking at Le Chatelier's principle! Thanks!!!

What an AWESOME explanation!! you have just lightened my road 😃thank you very much .

you're the best, thanks a lot.

Saved me once again ❤ thanks for doing what you do!

thank you so much i struggled so much with this topic

Thanks to this wonderful video! But I still don't understand that why -COOH is still -COOH after protonation and also why CH3NH3+ is still CH3NH3+ after protonation?

@ time 13:15, you wrote glycine as having only one H on the Nitrogen, when it actually has 2 H's. This really confused when you started to count charges...

You are a tremendous teacher.

Clear and simple as always, thank you.

For the last example how does HN got to H3N

Very clear and concise. Thank you so much!

Wow you are amazing. I love it!

Very good explaination

this helped me on a biochem question, thank you

Can someone answer this for me? I thought a molecule that has more H+ ions is BASIC and molecules that don't have that many H+ is acidic? Right or wrong?? for example which is the base and which is the acid of these 2......NaH2PH4 and NaHPO4 and why?

Thank you.You made it so simple

This is such a good explanation thank you!

U just saved my life,Thank u

Thx u so much! ❤

This is a very good explanation, thank you.

Really helpful. Thank you!

LET HER COOK!!! wow, you just earned a subsciber!

I love your explanation, it-s simply made and just enough :=)

god bless you for this amazing video

Hi, thanks for the video. But why at pH13, amino group did not deprotonate?

For pH of 13 for glycine, shouldnt the amino group be deprotonated and not protonated?

just wanted to clarify, at ph=13, the ph is greater than pka 9.6 of amino group, so amino group should be deprotonated to NH2 from NH3+ right? and thats why you get the charge on the amino group as 0?

It's so helpful! Thank you!!!

omg this makes a ton of sense

Shouldn't the amine on GLY be de-porotonated at pH 13 because pH>pKa? To go from neutral NH2 to NH??

very, very helpful! Thank you so much!

So you said that the neutral form cannot exist, but that the zwitterion is the neutral form and then you claimed that it is the most common form, please elaborate I'm confused

THANK YOUUU!! I finally understood what to do if pKa is equal to pH! God bless you (//>^

great explanation !! thank you ..

Thank you!!! You are a blessing 😍

i love this! Thank you very helpful

Why is the amino acid Glycine represented with an NH group instead of an NH2 group, and the COOH group as the COO group?

This was great! Thank you!

Omg you are a godsend god bless you

what if you are working with basic amino acid that is already carrying +1 charge?

Bless you. I understand this well now :)

at 12:47, would it be NH2 instead of NH? and O- instead of O? I'm just a bit confused on what the starting molecule of glycine looks like.

I'm confused. Ka is a constant for any given acid, right? So how can it be proportional to the hydrogen concentration? Constants aren't proportional to things! Ahh!

Just to clarify, does the pH look at the solution, while the pKa looks at the molecule?

i was confident until you did the example with glycine and misdrew it... it got me so confused during the entire example and now I'm just really anxious and confused :( ... please fix this....

You are so great! TY!

Thankyou very much mam...❤❤💖💖💖

thanks for a great video!

THANKU CUTIE

I really love you, thanks !!!

Thank you so much !

bless this video

Thank you so much

Would you recommend memorizing the pKa values for all amino acids?

I have exams in 1hr, wish i saw this much before

Am confused, at 15:22, when you deprotonate NH2, shouldn't the charge become -1 instead of neutral?

Thatssss really helpfullll thanks

GOD BLESS YOU

Can't thank you enough!

Fantastic

Leah, do we need to memorize the pka of the R groups for the Acid Base A Acids for the MCAT? In those the range is +2- -2 correct?

thank you so much

why is carboxylic is charge zero when pH is 1?

Great video

Do you give tutorials about other chapters of Biochemistry?

at ph 13 why did the amine group get protanated ... is should be deprotonated ryt ? bcoz the surrounding has got less H+ ion they y did the NH was protonated ....im confused ..

Brilliant

Why do you have the Amine Group as "H2N" at the beginning of the video, but as "HN" at the end of the video?

Excellent job Leah, thanks a lot! Just one question, regarding the quiz on your website: In part 3, we are asked to find the charge of Cys at PH = 4. Pka values for Cys are as follows: (Pka(COOH):1,71, Pka (NH2): 10,78, Pka(R): 8,33 ). The solution suggests change 0 for the side chain. Could you please explain this to me? I would expect to see +1 for the side chain and not zero, as PH is much less than the Pka for side chain, which means that the side chain should get protonated (conveting to S2H+ from SH). Am I missing something? All help would be appreciated.

It's not log, it's lg.

I don’t know but why you are so concerned about acetic acid !!! Where is the amino acid in this whole lecture!!!!