Thank you for the knowledge shearing! You look great!

Informative as always! My go-to for skincare education. Thanks Dr Sam!!

Really helpful as always.. thank you! Off to buy Nightly.

Such a great video Dr Sam 💕💕. I’ve been on your Flawless system for almost 3 years now. Not really sure how to go about increasing the Flawless Nightly, it does wonders for my skin. I’ve never had any skin irritations since day one usage. I am kindof thinking 🤔 why change what’s working. But I am not sure 🤔 if the skin adapts to this percentage, which is why we need to increase. Thanks 🙏 again for all you help.

So far I have tried retinal, granactive retinoid, retinol 0.3%, and now I am trying adapelene... With each of them, I followed ALL the tricks and tips, introduced it very gradually for months, sandwiched, removed other actives, used a lot of supportive skincare...and after some months, my skin would just get so irritated and inflamed (and it is not the typical purging of flakiness, but red inflamed bumps with small pustules). It feels like the more I go, the worse it is :( I think I might need to give up altogether 😭

I use the Granactive Retinoid, and my oh my... it reacts fast with less to no irritation on my face. Got skin purging in my first 3 days, but now, just in a week, all the effects subside. Most of my skin parts are smoother and the pores seem to shrink.

Adapalene (beginning with epiduo then switching to straight adapalene) has truly been a game changer for my extremely oily and acne prone skin. I had horrible acne as a teen even once having a cyst/nodule so big that my Curology derm told me to go to urgent care. The past few years my skin has started to look much more normal, i definitely still have acne but I finally feel like a NORMAL PERSON with occasional acne rather than a dirty freak with tumors all over his face. And it’s like 20 bucks per tube and a tube lasts me more than 4 months

Hi Dr Bunting could you make a video about high frequency devices please?

What do you think of Medik8 crystal retinaldehyde 2%? Great video!

Hello Thank you for this interesting vidéo. I am 65 and I am using the Ordinary 0.5 retinol every Night, no irritation. My concern : wrinkles. Should I use the Granactive retinol 2 % émulsion instead? Thank you in advance for your answer. Ariane

Thanks for your clear & concise explanation of the different forms of retinoids. I’ve watched many videos on this topic over the years, but this was the best IMO. I don’t know that I knew about the packaging aspect prior to this (I know vitamin C should be in light protective packaging). Thanks again.

Wish your consultations were affordable

I wish you had included the bar graph of efficacy & irritation for retinaldehyde

I think my dehydrogenase enzymes are set to "turbo" because the main difference I notice on my skin between retinol, retinaldehyde, and tretinoin is speed: each gets me to the same result, but tretinoin just works faster. I can get an acute erythema the day after using tretinoin that basically looks like a sunburn, so I keep retinaldehyde on hand in case I'm going anywhere I need to look professional the day after a retinoid night. I recently learned the hard way, however, that the rate-limiting effect of retinoic acid entering the skin that using metabolic precursors like retinaldehyde produces has a slight downside: I tried a 0.1% retinaldehyde, which, in hindsight, was too strong for my skin, and got "time-released" irritation for the next 5 or 6 days. By contrast, using too strong or large of an applied quantity of tretinoin will give me irritation out to about day 3, albeit much more intensely. So even with the OTC retinoids, it's important to exercise caution: 0.06 % seems to be my skin's limit for retinaldehyde, and I discovered years ago that 0.3 % was the sweet spot for my skin with retinol 😁

How can you build the strenght of retinol or retinal if you are using only products over the counter which have fixed quantities of ingredients?

Would u recommend tranexamic acid topically to fade red acne scars, and would the use of tranexamic acid cause more acne?

Hey! I wanna know if phone light and tv (artificial lights) affect the tretinoin?? !

Would you be able to cover and talk about adapalene and how it is different from the OTC retinoids talked about in this video? I have heard that adapalene is best for people with acne and not for anti aging. Is this true?

Granactive retinoid 2% in squalane is useful for milia?and lactic acid

Thank you for this wonderful video !!! I use your night serum ‘Nightly’ and use it every day without issues. What would I have to do if I wanted to increase the potency ? Will you make more potent serums if the kind ? Or should I move to another retinoid? Thank you ❤

Ohboy. So, I went to the dematologist. I used to have a dry skin, and a sensitive one, so I asked for non-perfumed products. I asked for a retinol or better because of my age (fine lines, big pores, uneven skin, acne and dark spots, uneven skintone). Never used a retinoid/retinol before. She suggested Avene cleanance women night smoothing cream (0.1 % retinaldehyde). I asked her about starting out and not applying it every 3 days at first, and she just said nono, use it every day (???!!??) just increase the amount bit by bit. She also said to use Avene hydra (think it's a barier repair one) as a day cream. She said cerave balm was too thick to use on face (although the pot says face and body?). Hmmmm, think I'll start out with a granactive and build my way up really. Her approach seems wild and too harsh for me. Heard people sandwiching retinols even between 2 layers of cerave. Derm also said not to use it on my neck, after I asked, but think I'll try the granactive on my neck since i have painful horonal acne there. And those won't go away for ages. Also after stopping to use cerave on my face, my eyelids are rough, raw and have started to use it again, because applying cream stung even. Rest face seems ok. She says I have oily skin, but, no? :p

before this video I ordered the Ordinary 0.2 in squalane. as entering in my mid 2os hope it works for the years demange. Thank you so much youre a such gem , learning so much from you. ♥️🥺

Hello,I have some allergies, and I have pigmentation, how to treat, I have tried to book a appointment with yourself , but no answer from email or phone call,

Thanks for a great video! Why is tretinoin actually on prescription in most countries? We only talk about how good it is, so one could argue that everyone should be able to enjoy it! :) Could it somehow be dangerous to use (long term)?

please create a niacinamide free nightly retinol serum, dr sam! :(

I have been using tretinoin but now i think it is giving me dry eyes. Should i shift to granactive retinoid. Would it be better for my dry eyes.

I was put on Retin-A when I was 12 for acne. I used it for about a decade and then stopped. When I hit 30 I thought I needed anti-aging help so I started on a 1% retinol serum. I have used that for the last decade +. Not sure if I should switch back to a prescription or just continue to bathe in the 1% serum.

What kind should I be using for Melasma/pigmentation? Thanks in advance.

How to use tret 0.025 after using adapalene 0.1? I used once a week and used the sandwich method at first, do i still need to start like this with tret?

ive been at 0.025% tret for 2 years. is the goal to move up to 1%? i thought all versions of tret were comparably efficacious after a certain period of time?

I've been using adapalene (Differin) for about six months and still can't use it every day from irritation. I know it's the best thing for my skin so I use three times a week. Still the best stuff I use for the occasion break out.

My wife has always wondered why she can get all your products in the ROI but can't get the serums???

❤️❤️❤️

Wayne Goss did a video on ‘contact therapy’ using Tretinoin. I have been doing this and am up to one hour nightly. Dr. Sam, what are your thoughts on this? Thanks!

Still don't understand