Why do Nondepolarizing muscle relaxants cause Fade with TOF monitoring?
Пікірлер: 53
@lbowlesrn7 жыл бұрын
i NEEDED someone to break this down for me simply and with moving pictures, THANK YOU SO MUCH!!! I ACTUALLY UNDERSTAND THIS NOW!!!
@WooPoo200710 жыл бұрын
Thanks for the breakdown and thorough explanation. It truly helped. And while I'm no longer in the Army, hearing "let me orient you" made me crack a smile.
@dancingwater15824 ай бұрын
Clear presentation. Just the right pace. Learning has occurred! Talented, capable and knowledgeable instructor. Great teachers are few and far between. Thank you, Michael Bentley, PhD!
@xDomglmao3 жыл бұрын
Guy deserves an award for teaching. Would you be so kind to explain the pattern visible after using depol agents?
@kirkgiles413611 жыл бұрын
An awesome video that was even better when view in sequence w/ the video explaining twitch.
@manuelloera59954 ай бұрын
Love the explanation, thank you sir!
@emilymoore789710 жыл бұрын
Great video, I'm a nurse in the Army Reserves attending Anesthesia school in Pennsylvania! Thanks so much
@mariotorres29936 жыл бұрын
This video really helps a lot to visualize the depletion of Ach. But @ 7:27 the doctor says that Ach has to stay away from pseudo cholinesterase. He should have said that Ach should stay away from True Cholinesterase which is the one that metabolizes Ach.
@AhsanKhan19983 жыл бұрын
He says "acetylcholinesterase" Edit: now that I hear it again, it does sound like he says "pseudo"
@Devilishsuki5 жыл бұрын
Thank you very helpful. Currently studying for the ICU part 1 examination in Australia :)
@xDomglmao3 жыл бұрын
so...did you pass :D?
@Devilishsuki3 жыл бұрын
xDomglmao yes! Thanks for asking! Though this topic did not come up for me, it was the subject of one of my practice vivas
@xDomglmao3 жыл бұрын
@@Devilishsuki Glad to hear that! :D Grats!
@jephh8 ай бұрын
Sukey I almost stopped watching this video 20 seconds in but because of your comment I watched the whole thing. It is good.
@sandysara84232 жыл бұрын
Very helpful, thank you very much 🙏
@MohamedKandilMD9 жыл бұрын
That was really helpful Dr. Bentley thank you very much but why do we also see fading pattern in phase II of depolarizing blockers?
@xDomglmao3 жыл бұрын
same question here!
@adeelkazmi969111 ай бұрын
Wow…simply amazing or amazingly simple u made it
@MambaCool205 ай бұрын
Thank you Sir 🙏🏾
@sonjaherzog57228 жыл бұрын
So helpful! Thank you so much!
@priyalhingrajiya2292 жыл бұрын
Thank you so much , so much understanding and enjoyable video 👍🏻👍🏻
@drnykterstein_2 жыл бұрын
This video was a godsend! But I dont understand the same thing for the phase 2 of Depolarizing blockers.
@seanbernard60005 жыл бұрын
Makes me wish I went to USAGPAN
@leetabgolden4 жыл бұрын
Thanks for this great brief!
@brwnbaldie2 жыл бұрын
Thank you!
@abeltsehay85335 жыл бұрын
very helpful, thank you!!
@dennerdovandojr.88784 жыл бұрын
Great video. Thanks!
@zipfish12310 ай бұрын
Great video. I want to draw a parallel to succinylcholine: Is phase 2 block caused by desensitization of the presynaptic nicotinic receptors (rather than direct antagonism as seen with non-depolarizing agents)? I'm having a hard time understanding why this would only occur at high doses.
@radhika12182 жыл бұрын
Thank you 🙏
@broganthomas22595 жыл бұрын
Thank you !!
@pankhuridhawan43934 жыл бұрын
Thankyou so much
@drmohobaidullah92288 жыл бұрын
thank you so much it really helped
@Jagadeesh_Gade394 жыл бұрын
So helpful. Tq
@soulmatesr6410 жыл бұрын
Very useful
@tubakhalid90013 жыл бұрын
Magical✨
@mastakeaton10 жыл бұрын
awesome!
@paryjameel8684 жыл бұрын
Thank u I’m pary from iraq
@alexanderbrigantty30689 жыл бұрын
best video ever
@ElenaRox19948 жыл бұрын
why is he wearing army clothes teaching medicine? extremely helpful and clear though! Wonderful simple diagrams~ easy to understand! Thank you!! :)
@chrisopaas49878 жыл бұрын
+ElenaRox1994 Because the army also deal with medicine. Actually the wars up trough the years has improved the surgical knowledge and skills that no hospital could ever experience. The military medical branch is a very important branch of the military.
@ElenaRox19948 жыл бұрын
Jorge Arizpe wow i see.. thank you!
@ryanbrunner56228 жыл бұрын
what does the presynaptic nicotinic receptor do? you explain the blocker is competing there but what does it NORMALLY do... I feel like thats essential in understanding this, and you dont explain it. for that reason.. thumbs down you just say positive feedback mechanism.. what are you talking about specifically? -First Year medical student
@martinyowa8 жыл бұрын
+Ryan Brunner....... presynaptic it has acetylcholine a neuron transmitter which attach to post synaptic. the below one in the diagram to open a channel called na/k channel which lead to influx of sodium from out side to inside n efflux of potassium from inside to outside which lead to depolarization
@ane288294 жыл бұрын
PREsynaptic receptors move the next set Ach filled vesicles to the “front line” (the edge of nicotinic nerve for preparation) and when another action potential comes and stimulates Ca2+ influx (which destabilizes the proteins that hold the vesicles in place) the “front line” is ready for release into the synaptic cleft. I know this is 4yrs old but I thought this reply may be helpful for others in the future -SRNA
@ane288294 жыл бұрын
Ryan Brunner the other response is true for POSTsynaptic nicotinic muscle receptors NOT PRE-. When Ach is released not all diffuses time the motor end plate, a fraction bind to PRE (Pos Feedback Mech).
@xDomglmao3 жыл бұрын
@@ane28829 Thank you very much!
@pesmobile-progamer13273 жыл бұрын
@@ane28829 i think u also need to open a youtube channel U explain superbly
@khebhh8 жыл бұрын
Takes a decade to get to the point. Could have been concise and to the point. Anyway thanks for making the basic clear.
@sunilbishnoi13646 жыл бұрын
You take so much time to explain a single point but ok